JP2006510650A5 - - Google Patents

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Publication number
JP2006510650A5
JP2006510650A5 JP2004558065A JP2004558065A JP2006510650A5 JP 2006510650 A5 JP2006510650 A5 JP 2006510650A5 JP 2004558065 A JP2004558065 A JP 2004558065A JP 2004558065 A JP2004558065 A JP 2004558065A JP 2006510650 A5 JP2006510650 A5 JP 2006510650A5
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Japan
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unsubstituted
mono
hydroxy
carbon atom
compound according
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JP2004558065A
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JP2006510650A (ja
JP4490285B2 (ja
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Priority claimed from PCT/EP2003/014055 external-priority patent/WO2004052869A1/en
Publication of JP2006510650A publication Critical patent/JP2006510650A/ja
Publication of JP2006510650A5 publication Critical patent/JP2006510650A5/ja
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Publication of JP4490285B2 publication Critical patent/JP4490285B2/ja
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Claims (2)

  1. Ｒ8がヒドロキシ又はジメチルアミンである、請求項３７記載の化合物。
  2. Ｒ4が、
    環炭素原子により結合している非置換の５員又は６員芳香族複素環（前記５員又は６員芳香族複素環は、硫黄、酸素又は窒素から選択される１個のヘテロ原子を含有している）；又は
    環炭素原子により結合している非置換又は一置換の６員アリール環（前記一置換アリール環は、前記結合炭素原子以外の環炭素原子の位置において、クロロ、ブロモ、ニトロ、アミノ、メチル、メトキシ又はヒドロキシからなる群より選択される置換基で一置換されている）
    から選択される、請求項１記載の化合物。
JP2004558065A 2002-12-12 2003-12-11 ５置換ピラジン又はピリジングルコキナーゼ活性化物質 Expired - Fee Related JP4490285B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43280602P 2002-12-12 2002-12-12
US52453103P 2003-11-24 2003-11-24
PCT/EP2003/014055 WO2004052869A1 (en) 2002-12-12 2003-12-11 5-substituted-pyrazine or pyridine glucokinase activators

Publications (3)

Publication Number Publication Date
JP2006510650A JP2006510650A (ja) 2006-03-30
JP2006510650A5 true JP2006510650A5 (ja) 2010-04-08
JP4490285B2 JP4490285B2 (ja) 2010-06-23

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JP2004558065A Expired - Fee Related JP4490285B2 (ja) 2002-12-12 2003-12-11 ５置換ピラジン又はピリジングルコキナーゼ活性化物質

Country Status (27)

Country Link
US (1) US7132425B2 (ja)
EP (1) EP1572670B1 (ja)
JP (1) JP4490285B2 (ja)
KR (1) KR100743890B1 (ja)
AR (1) AR046244A1 (ja)
AT (1) ATE370936T1 (ja)
AU (1) AU2003292229B2 (ja)
BR (1) BR0317268A (ja)
CA (1) CA2506441C (ja)
CY (1) CY1106989T1 (ja)
DE (1) DE60315886T2 (ja)
DK (1) DK1572670T3 (ja)
ES (1) ES2291697T3 (ja)
HK (1) HK1085481A1 (ja)
HR (1) HRP20050512A2 (ja)
MX (1) MXPA05006250A (ja)
MY (1) MY141521A (ja)
NO (1) NO330139B1 (ja)
NZ (1) NZ540298A (ja)
PA (1) PA8592001A1 (ja)
PE (1) PE20040801A1 (ja)
PL (1) PL377551A1 (ja)
PT (1) PT1572670E (ja)
RU (1) RU2310648C2 (ja)
TW (1) TW200426139A (ja)
UY (1) UY28121A1 (ja)
WO (1) WO2004052869A1 (ja)

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