JP2006504787A5 - - Google Patents
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- Publication number
- JP2006504787A5 JP2006504787A5 JP2004550230A JP2004550230A JP2006504787A5 JP 2006504787 A5 JP2006504787 A5 JP 2006504787A5 JP 2004550230 A JP2004550230 A JP 2004550230A JP 2004550230 A JP2004550230 A JP 2004550230A JP 2006504787 A5 JP2006504787 A5 JP 2006504787A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- group
- artemisinin
- endoperoxide
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 11
- 208000015181 infectious disease Diseases 0.000 claims 7
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 claims 6
- 229960004191 artemisinin Drugs 0.000 claims 6
- 229930101531 artemisinin Natural products 0.000 claims 6
- 102000014150 Interferons Human genes 0.000 claims 4
- 108010050904 Interferons Proteins 0.000 claims 4
- 229940079322 interferon Drugs 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 208000035473 Communicable disease Diseases 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 229910052711 selenium Inorganic materials 0.000 claims 3
- 229910052717 sulfur Inorganic materials 0.000 claims 3
- 241000710781 Flaviviridae Species 0.000 claims 2
- 208000005176 Hepatitis C Diseases 0.000 claims 2
- 241001493065 dsRNA viruses Species 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 229930004725 sesquiterpene Natural products 0.000 claims 2
- 150000004354 sesquiterpene derivatives Chemical class 0.000 claims 2
- 241000283690 Bos taurus Species 0.000 claims 1
- 206010008631 Cholera Diseases 0.000 claims 1
- 241000282898 Sus scrofa Species 0.000 claims 1
- 206010051511 Viral diarrhoea Diseases 0.000 claims 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42268302P | 2002-10-31 | 2002-10-31 | |
| PCT/US2003/034431 WO2004041176A2 (en) | 2002-10-31 | 2003-10-29 | The use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis c, bovine viral diarrhea and classical swine fever virus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006504787A JP2006504787A (ja) | 2006-02-09 |
| JP2006504787A5 true JP2006504787A5 (https=) | 2006-09-14 |
| JP4594734B2 JP4594734B2 (ja) | 2010-12-08 |
Family
ID=32312544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004550230A Expired - Fee Related JP4594734B2 (ja) | 2002-10-31 | 2003-10-29 | Ｃ型肝炎、牛ウイルス性下痢症及び豚コレラウイルスを含むフラビウイルス科ウイルスにより生起される感染症の治療のためのエンドペルオキシド類の使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7842719B2 (https=) |
| EP (1) | EP1585524B1 (https=) |
| JP (1) | JP4594734B2 (https=) |
| CN (1) | CN100430061C (https=) |
| AT (1) | ATE473745T1 (https=) |
| AU (1) | AU2003287259A1 (https=) |
| CA (1) | CA2501584C (https=) |
| DE (1) | DE60333392D1 (https=) |
| ES (1) | ES2348536T3 (https=) |
| PT (1) | PT1585524E (https=) |
| WO (1) | WO2004041176A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3257509A1 (en) | 2003-02-12 | 2017-12-20 | Georgetown University | Use of artemisinin and related compounds for treating anorectal squamous cell cancer induced by human papilloma virus |
| ES2245248B1 (es) * | 2004-06-09 | 2007-02-16 | Universidad De Salamanca | Uso de la artemisinina y sus derivados en la fabricacion de medicamentos utiles como agentes antiviricos. |
| KR100824106B1 (ko) * | 2006-05-30 | 2008-04-21 | 주식회사 씨티씨바이오 | 흰반점바이러스를 치료 또는 예방하기 위한 조성물 및 방법 |
| WO2008010620A1 (en) * | 2006-07-21 | 2008-01-24 | Ben's Lab Co., Ltd. | Composition comprising the crude drug extracts for improving liver function |
| BRPI0715714A2 (pt) * | 2006-08-25 | 2014-03-11 | Wyeth Corp | Métodos para diminuir a frequência de emergência de uma infecção viral de hepatite c resistente ao tratamento, para atrasar a emergência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir o nível de resistência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir a emergência de uma infecção viral de hepatite c resistente a hcv-796, para identificar um indivíduo com uma probabilidade diminuída de responder a uma terapia viral anti-hepatite c, para monitorar, diagnosticar ou prognosticar a infecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar o curso de tratamento de uma infecção viral de hepatite c em um paciente, para prognosticar o desenvolvimento de um ainfecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar a infecção viral de hepatite c em um paciente e para diagnosticar o desenvolvimento de uma infecção viral de hepatite ao tratamento em um paciente |
| EP2310393A4 (en) * | 2008-06-17 | 2011-06-22 | Hhv 6 Foundation | ARTEMISININE AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS |
| CN102731464B (zh) * | 2011-04-12 | 2014-07-23 | 沈阳药科大学 | 一个倍半萜内酯化合物、制备方法及其应用 |
| US20130012470A1 (en) * | 2011-07-07 | 2013-01-10 | Humanitas Technology, LLC | Antiviral compositions and methods of their use |
| US20130028882A1 (en) | 2011-07-07 | 2013-01-31 | Humanitas Technology, LLC | Antiviral compositions and methods of their use |
| BR112014026158A2 (pt) * | 2012-04-18 | 2017-06-27 | Hadasit Med Res Service | métodos e composições para o tratamento de infecções virais |
| FR2989588A1 (fr) * | 2012-04-19 | 2013-10-25 | Centre Nat Rech Scient | Composes pour la prevention ou le traitement des infections par des virus de la famille des flaviviridae |
| CN102755316A (zh) * | 2012-07-16 | 2012-10-31 | 中国科学院武汉病毒研究所 | 青蒿素及其衍生物在制备治疗丙型肝炎病毒药物中的应用 |
| CN110139655A (zh) * | 2016-10-07 | 2019-08-16 | 纳维迪亚生物制药有限公司 | 诊断和治疗病毒性感染的化合物和方法 |
| GB201805665D0 (en) * | 2018-04-05 | 2018-05-23 | Univ Nottingham | Antiviral Compounds And Methods |
| WO2019232129A1 (en) * | 2018-05-30 | 2019-12-05 | The Board Of Regents Of The University Of Texas System | Treatment of viral infections and virally associated lesions with sequiterpene lactones |
| WO2021216385A1 (en) * | 2020-04-20 | 2021-10-28 | Tran Lloyd Hung Loi | Methods for the prophylaxis and treatment of covid and covid-19 |
| CN112245424B (zh) * | 2020-10-19 | 2021-09-21 | 中国医学科学院医药生物技术研究所 | 一种没药烷倍半萜结构类似物在制备抗冠状病毒药物中的用途 |
| CN112294795B (zh) * | 2020-11-17 | 2022-03-29 | 北京化工大学 | 蒿甲醚在治疗和预防柯萨奇病毒感染中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW198722B (https=) | 1990-05-07 | 1993-01-21 | Hoechst Ag | |
| CN1058717A (zh) * | 1990-08-08 | 1992-02-19 | 中国人民解放军军事医学科学院微生物流行病研究所 | 抗疟新药—复方蒿甲醚及其制备方法 |
| CN1035767C (zh) * | 1992-11-10 | 1997-09-03 | 罗宣德 | 新的青蒿素衍生物及其用途 |
| CN1105238A (zh) * | 1992-11-10 | 1995-07-19 | 中国预防医学科学院病毒学研究所 | 抗aids病毒的药物组合物 |
| US5726203A (en) * | 1993-07-19 | 1998-03-10 | Li; Zelin | Qinghaosu derivatives against AIDS |
| DE4415539C2 (de) * | 1994-05-03 | 1996-08-01 | Osama Dr Dr Med Omer | Pflanzen mit virustatischer und antiviraler Wirkung |
| CN1049435C (zh) * | 1994-11-09 | 2000-02-16 | 中国科学院上海药物研究所 | 含苯基和杂环基的青蒿素衍生物及其制备方法 |
| DE19902924A1 (de) | 1999-01-26 | 2000-08-03 | Hassan Jomaa | Verwendung von phosphororganischen Verbindungen zur prophylaktischen und therapeutischen Behandlung von Infektionen |
| CN1135974C (zh) | 2000-08-23 | 2004-01-28 | 重庆健桥医药开发有限公司 | 抗疟药新药复方双氢青蒿素 |
| AU2001295979A1 (en) | 2000-10-20 | 2002-04-29 | Ajinomoto Co., Inc. | Medicinal compositions, dose and method for treating malaria |
| EP3257509A1 (en) * | 2003-02-12 | 2017-12-20 | Georgetown University | Use of artemisinin and related compounds for treating anorectal squamous cell cancer induced by human papilloma virus |
-
2003
- 2003-09-16 US US10/664,008 patent/US7842719B2/en not_active Expired - Fee Related
- 2003-10-29 AU AU2003287259A patent/AU2003287259A1/en not_active Abandoned
- 2003-10-29 PT PT03781492T patent/PT1585524E/pt unknown
- 2003-10-29 JP JP2004550230A patent/JP4594734B2/ja not_active Expired - Fee Related
- 2003-10-29 CA CA002501584A patent/CA2501584C/en not_active Expired - Fee Related
- 2003-10-29 EP EP03781492A patent/EP1585524B1/en not_active Expired - Lifetime
- 2003-10-29 AT AT03781492T patent/ATE473745T1/de active
- 2003-10-29 WO PCT/US2003/034431 patent/WO2004041176A2/en not_active Ceased
- 2003-10-29 DE DE60333392T patent/DE60333392D1/de not_active Expired - Lifetime
- 2003-10-29 ES ES03781492T patent/ES2348536T3/es not_active Expired - Lifetime
- 2003-10-29 CN CNB2003801026935A patent/CN100430061C/zh not_active Expired - Fee Related