ATE473745T1 - Verwendung von endoperoxiden zur behandlungvon infektionen durch flaviviridae, einschliesslich hepatitis c, viral rinder-diarrhöeund klassischer schweinefieber-virus - Google Patents

Verwendung von endoperoxiden zur behandlungvon infektionen durch flaviviridae, einschliesslich hepatitis c, viral rinder-diarrhöeund klassischer schweinefieber-virus

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Publication number
ATE473745T1
ATE473745T1 AT03781492T AT03781492T ATE473745T1 AT E473745 T1 ATE473745 T1 AT E473745T1 AT 03781492 T AT03781492 T AT 03781492T AT 03781492 T AT03781492 T AT 03781492T AT E473745 T1 ATE473745 T1 AT E473745T1
Authority
AT
Austria
Prior art keywords
endoperoxides
artemisinin
treatment
hepatitis
flaviviridae
Prior art date
Application number
AT03781492T
Other languages
German (de)
English (en)
Inventor
Jan Vandenkerckhove
Benedikt Sas
Eric Peys
Hemel Johan Van
Johan Neyts
Original Assignee
Kemin Foods Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kemin Foods Lc filed Critical Kemin Foods Lc
Application granted granted Critical
Publication of ATE473745T1 publication Critical patent/ATE473745T1/de

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03781492T 2002-10-31 2003-10-29 Verwendung von endoperoxiden zur behandlungvon infektionen durch flaviviridae, einschliesslich hepatitis c, viral rinder-diarrhöeund klassischer schweinefieber-virus ATE473745T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42268302P 2002-10-31 2002-10-31
PCT/US2003/034431 WO2004041176A2 (en) 2002-10-31 2003-10-29 The use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis c, bovine viral diarrhea and classical swine fever virus

Publications (1)

Publication Number Publication Date
ATE473745T1 true ATE473745T1 (de) 2010-07-15

Family

ID=32312544

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03781492T ATE473745T1 (de) 2002-10-31 2003-10-29 Verwendung von endoperoxiden zur behandlungvon infektionen durch flaviviridae, einschliesslich hepatitis c, viral rinder-diarrhöeund klassischer schweinefieber-virus

Country Status (11)

Country Link
US (1) US7842719B2 (https=)
EP (1) EP1585524B1 (https=)
JP (1) JP4594734B2 (https=)
CN (1) CN100430061C (https=)
AT (1) ATE473745T1 (https=)
AU (1) AU2003287259A1 (https=)
CA (1) CA2501584C (https=)
DE (1) DE60333392D1 (https=)
ES (1) ES2348536T3 (https=)
PT (1) PT1585524E (https=)
WO (1) WO2004041176A2 (https=)

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* Cited by examiner, † Cited by third party
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EP3257509A1 (en) 2003-02-12 2017-12-20 Georgetown University Use of artemisinin and related compounds for treating anorectal squamous cell cancer induced by human papilloma virus
ES2245248B1 (es) * 2004-06-09 2007-02-16 Universidad De Salamanca Uso de la artemisinina y sus derivados en la fabricacion de medicamentos utiles como agentes antiviricos.
KR100824106B1 (ko) * 2006-05-30 2008-04-21 주식회사 씨티씨바이오 흰반점바이러스를 치료 또는 예방하기 위한 조성물 및 방법
WO2008010620A1 (en) * 2006-07-21 2008-01-24 Ben's Lab Co., Ltd. Composition comprising the crude drug extracts for improving liver function
BRPI0715714A2 (pt) * 2006-08-25 2014-03-11 Wyeth Corp Métodos para diminuir a frequência de emergência de uma infecção viral de hepatite c resistente ao tratamento, para atrasar a emergência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir o nível de resistência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir a emergência de uma infecção viral de hepatite c resistente a hcv-796, para identificar um indivíduo com uma probabilidade diminuída de responder a uma terapia viral anti-hepatite c, para monitorar, diagnosticar ou prognosticar a infecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar o curso de tratamento de uma infecção viral de hepatite c em um paciente, para prognosticar o desenvolvimento de um ainfecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar a infecção viral de hepatite c em um paciente e para diagnosticar o desenvolvimento de uma infecção viral de hepatite ao tratamento em um paciente
EP2310393A4 (en) * 2008-06-17 2011-06-22 Hhv 6 Foundation ARTEMISININE AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS
CN102731464B (zh) * 2011-04-12 2014-07-23 沈阳药科大学 一个倍半萜内酯化合物、制备方法及其应用
US20130012470A1 (en) * 2011-07-07 2013-01-10 Humanitas Technology, LLC Antiviral compositions and methods of their use
US20130028882A1 (en) 2011-07-07 2013-01-31 Humanitas Technology, LLC Antiviral compositions and methods of their use
BR112014026158A2 (pt) * 2012-04-18 2017-06-27 Hadasit Med Res Service métodos e composições para o tratamento de infecções virais
FR2989588A1 (fr) * 2012-04-19 2013-10-25 Centre Nat Rech Scient Composes pour la prevention ou le traitement des infections par des virus de la famille des flaviviridae
CN102755316A (zh) * 2012-07-16 2012-10-31 中国科学院武汉病毒研究所 青蒿素及其衍生物在制备治疗丙型肝炎病毒药物中的应用
CN110139655A (zh) * 2016-10-07 2019-08-16 纳维迪亚生物制药有限公司 诊断和治疗病毒性感染的化合物和方法
GB201805665D0 (en) * 2018-04-05 2018-05-23 Univ Nottingham Antiviral Compounds And Methods
WO2019232129A1 (en) * 2018-05-30 2019-12-05 The Board Of Regents Of The University Of Texas System Treatment of viral infections and virally associated lesions with sequiterpene lactones
WO2021216385A1 (en) * 2020-04-20 2021-10-28 Tran Lloyd Hung Loi Methods for the prophylaxis and treatment of covid and covid-19
CN112245424B (zh) * 2020-10-19 2021-09-21 中国医学科学院医药生物技术研究所 一种没药烷倍半萜结构类似物在制备抗冠状病毒药物中的用途
CN112294795B (zh) * 2020-11-17 2022-03-29 北京化工大学 蒿甲醚在治疗和预防柯萨奇病毒感染中的应用

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TW198722B (https=) 1990-05-07 1993-01-21 Hoechst Ag
CN1058717A (zh) * 1990-08-08 1992-02-19 中国人民解放军军事医学科学院微生物流行病研究所 抗疟新药—复方蒿甲醚及其制备方法
CN1035767C (zh) * 1992-11-10 1997-09-03 罗宣德 新的青蒿素衍生物及其用途
CN1105238A (zh) * 1992-11-10 1995-07-19 中国预防医学科学院病毒学研究所 抗aids病毒的药物组合物
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Also Published As

Publication number Publication date
AU2003287259A8 (en) 2004-06-07
CN100430061C (zh) 2008-11-05
WO2004041176A2 (en) 2004-05-21
US20050059647A1 (en) 2005-03-17
DE60333392D1 (de) 2010-08-26
CA2501584A1 (en) 2004-05-21
WO2004041176A3 (en) 2004-10-07
JP2006504787A (ja) 2006-02-09
CA2501584C (en) 2009-03-10
JP4594734B2 (ja) 2010-12-08
PT1585524E (pt) 2010-10-19
US7842719B2 (en) 2010-11-30
AU2003287259A1 (en) 2004-06-07
EP1585524A4 (en) 2007-10-10
CN1711091A (zh) 2005-12-21
ES2348536T3 (es) 2010-12-09
EP1585524B1 (en) 2010-07-14
EP1585524A2 (en) 2005-10-19

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