JP2006503017A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006503017A5 JP2006503017A5 JP2004532284A JP2004532284A JP2006503017A5 JP 2006503017 A5 JP2006503017 A5 JP 2006503017A5 JP 2004532284 A JP2004532284 A JP 2004532284A JP 2004532284 A JP2004532284 A JP 2004532284A JP 2006503017 A5 JP2006503017 A5 JP 2006503017A5
- Authority
- JP
- Japan
- Prior art keywords
- human
- sequence
- immunogen
- immunogenic composition
- substitutions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002163 immunogen Effects 0.000 claims 51
- 102000003816 Interleukin-13 Human genes 0.000 claims 29
- 108090000176 Interleukin-13 Proteins 0.000 claims 29
- 238000006467 substitution reaction Methods 0.000 claims 22
- 101001076430 Homo sapiens Interleukin-13 Proteins 0.000 claims 17
- 102000019207 human interleukin-13 Human genes 0.000 claims 17
- 150000001413 amino acids Chemical class 0.000 claims 13
- 230000035772 mutation Effects 0.000 claims 11
- 210000001744 T-lymphocyte Anatomy 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 7
- 241000894007 species Species 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 102000014914 Carrier Proteins Human genes 0.000 claims 3
- 108010078791 Carrier Proteins Proteins 0.000 claims 3
- 241000282412 Homo Species 0.000 claims 3
- 230000005847 immunogenicity Effects 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 2
- 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 claims 1
- 241000606768 Haemophilus influenzae Species 0.000 claims 1
- 108091007491 NSP3 Papain-like protease domains Proteins 0.000 claims 1
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 claims 1
- 101710188053 Protein D Proteins 0.000 claims 1
- 101710132893 Resolvase Proteins 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 229940047650 haemophilus influenzae Drugs 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000018711 interleukin-13 production Effects 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229960000814 tetanus toxoid Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0220212A GB0220212D0 (en) | 2002-08-30 | 2002-08-30 | Vaccine |
| GB0304672A GB0304672D0 (en) | 2003-02-28 | 2003-02-28 | Vaccines |
| PCT/GB2003/003703 WO2004019974A2 (en) | 2002-08-30 | 2003-08-28 | Immunogenic composition comprising an il-13 element and t cell epitopes, and its therapeutic use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006503017A JP2006503017A (ja) | 2006-01-26 |
| JP2006503017A5 true JP2006503017A5 (enExample) | 2006-06-15 |
Family
ID=31980003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004532284A Pending JP2006503017A (ja) | 2002-08-30 | 2003-08-28 | Ｉｌ−１３要素及びｔ細胞エピトープを含む免疫原組成物並びにその治療上の使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060147417A1 (enExample) |
| EP (1) | EP1532172A2 (enExample) |
| JP (1) | JP2006503017A (enExample) |
| AR (1) | AR041086A1 (enExample) |
| AU (1) | AU2003259358A1 (enExample) |
| CA (1) | CA2496409A1 (enExample) |
| TW (1) | TW200407162A (enExample) |
| WO (1) | WO2004019974A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006503018A (ja) * | 2002-08-30 | 2006-01-26 | グラクソ グループ リミテッド | ワクチン |
| PL1711528T3 (pl) | 2003-12-23 | 2012-11-30 | Genentech Inc | Leczenie nowotworu nowymi przeciwciałami monoklonalnymi anty-IL13 |
| DE102004003572A1 (de) * | 2004-01-23 | 2005-08-18 | Bavarian Nordic A/S | Monoparamunitätsinducer basierend auf attenuierten Myxomaviren des Kaninchens |
| KR100639397B1 (ko) * | 2004-03-18 | 2006-10-26 | (주)에스제이바이오메드 | 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물 |
| MX2007005866A (es) | 2004-11-17 | 2007-11-12 | Amgen Inc | Anticuerpos monoclonales totalmente humanos para il-13. |
| GB0615881D0 (en) * | 2006-08-10 | 2006-09-20 | Univ Southampton | Novel peptide for treatment of asthma |
| US20110002955A1 (en) * | 2006-09-25 | 2011-01-06 | Sj Biomed Inc. | Anti-obese immunogenic hybrid polypeptides and anti-obese vaccine composition comprising the same |
| WO2011003138A1 (en) * | 2009-07-06 | 2011-01-13 | The Australian National University | Immunomodulating compositions comprising interleukin 13 inhibitors and uses therefor |
| US20160166637A1 (en) * | 2013-08-02 | 2016-06-16 | Virginia Tech Intellectual Properties, Inc. | Methods of treating a cancer through targeted disruption of alpha connexin 43-zonula occludens-1 (zo-1) interaction |
| BR112016004437A2 (pt) | 2013-09-13 | 2017-10-17 | Genentech Inc | métodos de imunoteste e de seleção de linhagem de células, anticorpos e kit |
| CN105722532A (zh) | 2013-09-13 | 2016-06-29 | 豪夫迈·罗氏有限公司 | 包含纯化的重组多肽的方法和组合物 |
| WO2019061297A1 (zh) * | 2017-09-29 | 2019-04-04 | 苏州工业园区唯可达生物科技有限公司 | 一种cd4辅助性t细胞表位融合肽及其疫苗 |
| EP3574915A1 (en) | 2018-05-29 | 2019-12-04 | Neovacs | Immunogenic product comprising il-4 and/or il-13 for treating disorders associated with aberrant il-4 and/or il 13 expression or activity |
| KR20210110842A (ko) | 2018-12-28 | 2021-09-09 | 유나이티드 바이오메디칼 인크. | 인터루킨 6(il-6)을 표적화하는 펩타이드 면역원 및 il-6 조절장애에 의해 영향을 받는 질환의 면역요법을 위한 이의 제형 |
| AU2022212600A1 (en) * | 2021-01-29 | 2023-08-17 | Bayer Animal Health Gmbh | Vaccine composition for breaking self-tolerance |
| JP2024531390A (ja) * | 2021-08-20 | 2024-08-29 | ネオヴァクス | ＩＬ－４および／またはＩＬ－１３ＲＮＡを含むｍＲＮＡワクチンおよびその使用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9717953D0 (en) * | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| US6296843B1 (en) * | 1998-04-03 | 2001-10-02 | The Penn State Research Foundation | Mutagenized IL 13-based chimeric molecules |
| WO2000065058A1 (en) * | 1999-04-23 | 2000-11-02 | Pharmexa A/S | Method for down-regulating il5 activity |
| AU1599301A (en) * | 1999-11-11 | 2001-06-06 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Modulating IL-13 activity using mutated IL-13 molecules that are antagonists or agonists of IL-13 |
| US6846486B1 (en) * | 2000-02-24 | 2005-01-25 | Advanced Biotherapy Concepts, Inc. | Method of treating allergy by administering an anti-histamine antibody |
| GB0105360D0 (en) * | 2001-03-03 | 2001-04-18 | Glaxo Group Ltd | Chimaeric immunogens |
-
2003
- 2003-08-28 CA CA002496409A patent/CA2496409A1/en not_active Abandoned
- 2003-08-28 TW TW092123745A patent/TW200407162A/zh unknown
- 2003-08-28 EP EP03791019A patent/EP1532172A2/en not_active Withdrawn
- 2003-08-28 AU AU2003259358A patent/AU2003259358A1/en not_active Abandoned
- 2003-08-28 AR ARP030103127A patent/AR041086A1/es not_active Application Discontinuation
- 2003-08-28 WO PCT/GB2003/003703 patent/WO2004019974A2/en not_active Ceased
- 2003-08-28 US US10/526,060 patent/US20060147417A1/en not_active Abandoned
- 2003-08-28 JP JP2004532284A patent/JP2006503017A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006503017A5 (enExample) | ||
| CA1340472C (en) | Universal t-cell epitope derived from p. faciparum circumsporosoite protein | |
| EP1092774B1 (en) | Borrelia burgdorferi OspA polypeptide for immunization against Lyme disease | |
| AU637049B2 (en) | Recombinant flagellin vaccines | |
| JP2002525060A5 (enExample) | ||
| WO1992000055A1 (en) | Compositions and methods for the prevention and diagnosis of lyme disease | |
| JP2005502314A5 (enExample) | ||
| CA2565925C (en) | Vaccine for periodontal disease | |
| JPS6251994A (ja) | クロ−ン化抗原 | |
| JPH08509371A (ja) | ライム病の予防及び治療のためのＯｓｐＣ抗原ワクチンの免疫原性製剤及びかかる抗原の調製のための組換え方法 | |
| EP3029073B1 (en) | Polyvalent chimeric ospc vaccinogen and diagnostic antigen | |
| JP2006501249A5 (enExample) | ||
| WO1993022341A1 (en) | Synthetic peptide vaccines for dental caries | |
| JPH02291271A (ja) | 発現伝播体を有する組成物 | |
| US20190117756A1 (en) | Immunogenic Compositions and Vaccines Derived From Bacterial Surface Receptor Proteins | |
| JP3135060B2 (ja) | ヘモフィルスインフルエンザｂ型菌の外皮膜タンパク質Ｐ２の部分断片を用いた接合体 | |
| US12220453B2 (en) | Compositions and treatments for Haemophilus influenzae | |
| CN101880328A (zh) | 微小隐孢子虫Th多表位基因和融合蛋白及其应用 | |
| JPH02223594A (ja) | ヒトライノウイルスペプチド | |
| AU2001271124B2 (en) | Peptides for the preparation of vaccines against bordetella pertussis and bordetella parapertussis | |
| CN1187372C (zh) | 人绒毛膜促性腺激素基因工程合成嵌合肽及其制备方法 | |
| AU2001271124A1 (en) | Peptides for the preparation of vaccines against bordetella pertussis and bordetella parapertussis | |
| CN1378560A (zh) | 治疗感染性疾病和免疫系统疾病的化合物及其使用方法 | |
| JPS63503197A (ja) | マラリアに対する保護免疫を与えるポリペプチド類 | |
| WO2002017960A1 (fr) | Vaccins contre $m(f)i$m(g)toxoplasma gondii$m(f)/i$m(g) |