JP2006104212A - 腫瘍の診断と治療のための組成物と方法 - Google Patents

腫瘍の診断と治療のための組成物と方法 Download PDF

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Publication number
JP2006104212A
JP2006104212A JP2005363921A JP2005363921A JP2006104212A JP 2006104212 A JP2006104212 A JP 2006104212A JP 2005363921 A JP2005363921 A JP 2005363921A JP 2005363921 A JP2005363921 A JP 2005363921A JP 2006104212 A JP2006104212 A JP 2006104212A
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seq
antibody
tat
polypeptide
amino acid
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Pending
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JP2005363921A
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Japanese (ja)
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JP2006104212A5 (enExample
Inventor
Avi J Ashkenazi
アシュケナジ,アヴィ,ジェー.
Audrey Goddard
ゴッダード,オードリー
Paul J Godowski
ゴドフスキー,ポール,ジェイ.
Austin L Gurney
ガーニー,オースティン,エル.
Paul Polakis
ポラキス,ポール
P Mickey Williams
ウィリアムス,ピー.ミッキー
William I Wood
ウッド,ウィリアム,アイ.
Thomas D Wu
ディー. ウー,トーマス
Zemin Zhang
チャン,ツオーミン
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Genentech Inc
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Genentech Inc
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Priority claimed from PCT/US2000/023328 external-priority patent/WO2001016318A2/en
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Priority claimed from PCT/US2001/006520 external-priority patent/WO2001068848A2/en
Priority claimed from PCT/US2001/017800 external-priority patent/WO2001093983A1/en
Priority claimed from PCT/US2001/019692 external-priority patent/WO2002000690A2/en
Priority claimed from PCT/US2001/021066 external-priority patent/WO2002008288A2/en
Priority claimed from PCT/US2001/021735 external-priority patent/WO2002008284A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2006104212A publication Critical patent/JP2006104212A/ja
Publication of JP2006104212A5 publication Critical patent/JP2006104212A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • C12N2310/12Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/15Nucleic acids forming more than 2 strands, e.g. TFOs

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  • Bioinformatics & Cheminformatics (AREA)
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  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
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  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2005363921A 2000-08-24 2005-12-16 腫瘍の診断と治療のための組成物と方法 Pending JP2006104212A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
PCT/US2000/023328 WO2001016318A2 (en) 1999-09-01 2000-08-24 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/006520 WO2001068848A2 (en) 2000-03-01 2001-02-28 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/017800 WO2001093983A1 (en) 2000-06-02 2001-06-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/019692 WO2002000690A2 (en) 2000-06-23 2001-06-20 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
PCT/US2001/021066 WO2002008288A2 (en) 2000-07-20 2001-06-29 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/021735 WO2002008284A2 (en) 2000-07-20 2001-07-09 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2002522275A Division JP2004520810A (ja) 2000-08-24 2001-08-23 腫瘍の診断と治療のための組成物と方法

Publications (2)

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JP2006104212A true JP2006104212A (ja) 2006-04-20
JP2006104212A5 JP2006104212A5 (enExample) 2008-09-18

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2005363921A Pending JP2006104212A (ja) 2000-08-24 2005-12-16 腫瘍の診断と治療のための組成物と方法
JP2006242365A Expired - Lifetime JP4602954B2 (ja) 2000-08-24 2006-09-07 インターロイキン−22ポリペプチド及びそれに結合する抗体の使用
JP2006252159A Pending JP2007077155A (ja) 2000-08-24 2006-09-19 腫瘍の診断と治療のための組成物と方法
JP2010177460A Pending JP2011019519A (ja) 2000-08-24 2010-08-06 インターロイキン−22ポリペプチド、それをコードする核酸並びに膵臓疾患の治療方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2006242365A Expired - Lifetime JP4602954B2 (ja) 2000-08-24 2006-09-07 インターロイキン−22ポリペプチド及びそれに結合する抗体の使用
JP2006252159A Pending JP2007077155A (ja) 2000-08-24 2006-09-19 腫瘍の診断と治療のための組成物と方法
JP2010177460A Pending JP2011019519A (ja) 2000-08-24 2010-08-06 インターロイキン−22ポリペプチド、それをコードする核酸並びに膵臓疾患の治療方法

Country Status (6)

Country Link
EP (2) EP2014298A3 (enExample)
JP (4) JP2006104212A (enExample)
AT (1) ATE412009T1 (enExample)
AU (1) AU2006230703A1 (enExample)
DE (1) DE60136281D1 (enExample)
ZA (2) ZA200301205B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
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KR101579218B1 (ko) 2007-12-26 2015-12-21 바이오테스트 아게 Cd138 발현성 종양 세포에 대한 표적화를 개선시키기 위한 방법 및 물질
CN101952315B (zh) 2007-12-26 2015-04-01 生物测试股份公司 靶向cd138的试剂及其应用
HRP20150143T1 (hr) 2007-12-26 2015-04-10 Biotest Ag Imunokonjugati koji ciljaju na cd138 i njihova upotreba
JP2020513574A (ja) * 2016-11-24 2020-05-14 ヒュベット バイオ, インコーポレイテッドHuvet Bio, Inc. 疾患の診断用組成物
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
EP4083058A3 (en) * 2018-11-07 2023-01-11 Applied Molecular Transport Inc. Delivery constructs for transcytosis and related methods

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