JP2006104212A - 腫瘍の診断と治療のための組成物と方法 - Google Patents

腫瘍の診断と治療のための組成物と方法 Download PDF

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Publication number
JP2006104212A
JP2006104212A JP2005363921A JP2005363921A JP2006104212A JP 2006104212 A JP2006104212 A JP 2006104212A JP 2005363921 A JP2005363921 A JP 2005363921A JP 2005363921 A JP2005363921 A JP 2005363921A JP 2006104212 A JP2006104212 A JP 2006104212A
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Prior art keywords
seq
antibody
tat
polypeptide
amino acid
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Pending
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JP2005363921A
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Japanese (ja)
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JP2006104212A5 (enExample
Inventor
Avi J Ashkenazi
アシュケナジ,アヴィ,ジェー.
Audrey Goddard
ゴッダード,オードリー
Paul J Godowski
ゴドフスキー,ポール,ジェイ.
Austin L Gurney
ガーニー,オースティン,エル.
Paul Polakis
ポラキス,ポール
P Mickey Williams
ウィリアムス,ピー.ミッキー
William I Wood
ウッド,ウィリアム,アイ.
Thomas D Wu
ディー. ウー,トーマス
Zemin Zhang
チャン,ツオーミン
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Genentech Inc
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Genentech Inc
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Priority claimed from PCT/US2000/023328 external-priority patent/WO2001016318A2/en
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Priority claimed from PCT/US2001/006520 external-priority patent/WO2001068848A2/en
Priority claimed from PCT/US2001/017800 external-priority patent/WO2001093983A1/en
Priority claimed from PCT/US2001/019692 external-priority patent/WO2002000690A2/en
Priority claimed from PCT/US2001/021066 external-priority patent/WO2002008288A2/en
Priority claimed from PCT/US2001/021735 external-priority patent/WO2002008284A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2006104212A publication Critical patent/JP2006104212A/ja
Publication of JP2006104212A5 publication Critical patent/JP2006104212A5/ja
Pending legal-status Critical Current

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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs

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  • Animal Behavior & Ethology (AREA)
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  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2005363921A 2000-08-24 2005-12-16 腫瘍の診断と治療のための組成物と方法 Pending JP2006104212A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
PCT/US2000/023328 WO2001016318A2 (en) 1999-09-01 2000-08-24 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/006520 WO2001068848A2 (en) 2000-03-01 2001-02-28 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/017800 WO2001093983A1 (en) 2000-06-02 2001-06-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/019692 WO2002000690A2 (en) 2000-06-23 2001-06-20 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
PCT/US2001/021066 WO2002008288A2 (en) 2000-07-20 2001-06-29 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/021735 WO2002008284A2 (en) 2000-07-20 2001-07-09 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2002522275A Division JP2004520810A (ja) 2000-08-24 2001-08-23 腫瘍の診断と治療のための組成物と方法

Publications (2)

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JP2006104212A true JP2006104212A (ja) 2006-04-20
JP2006104212A5 JP2006104212A5 (enExample) 2008-09-18

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2005363921A Pending JP2006104212A (ja) 2000-08-24 2005-12-16 腫瘍の診断と治療のための組成物と方法
JP2006242365A Expired - Lifetime JP4602954B2 (ja) 2000-08-24 2006-09-07 インターロイキン−22ポリペプチド及びそれに結合する抗体の使用
JP2006252159A Pending JP2007077155A (ja) 2000-08-24 2006-09-19 腫瘍の診断と治療のための組成物と方法
JP2010177460A Pending JP2011019519A (ja) 2000-08-24 2010-08-06 インターロイキン−22ポリペプチド、それをコードする核酸並びに膵臓疾患の治療方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2006242365A Expired - Lifetime JP4602954B2 (ja) 2000-08-24 2006-09-07 インターロイキン−22ポリペプチド及びそれに結合する抗体の使用
JP2006252159A Pending JP2007077155A (ja) 2000-08-24 2006-09-19 腫瘍の診断と治療のための組成物と方法
JP2010177460A Pending JP2011019519A (ja) 2000-08-24 2010-08-06 インターロイキン−22ポリペプチド、それをコードする核酸並びに膵臓疾患の治療方法

Country Status (6)

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EP (2) EP2014298A3 (enExample)
JP (4) JP2006104212A (enExample)
AT (1) ATE412009T1 (enExample)
AU (1) AU2006230703A1 (enExample)
DE (1) DE60136281D1 (enExample)
ZA (2) ZA200301202B (enExample)

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US9446146B2 (en) 2007-12-26 2016-09-20 Biotest Ag Methods and agents for improving targeting of CD138 expressing tumor cells
PL2242772T3 (pl) * 2007-12-26 2015-05-29 Biotest Ag Immunokonjugaty nakierowane na CD138 i ich zastosowanie
ES2475201T3 (es) 2007-12-26 2014-07-10 Biotest Ag Agentes dirigidos contra CD138 y usos de los mismos
EP3546943A4 (en) * 2016-11-24 2020-09-16 Huvet Bio, Inc. DIAGNOSIS OF DISEASES
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
ES2911075T3 (es) * 2018-11-07 2022-05-17 Applied Molecular Transport Inc Constructos de administración para transcitosis y métodos relacionados

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