JP2006104212A5 - - Google Patents
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- Publication number
- JP2006104212A5 JP2006104212A5 JP2005363921A JP2005363921A JP2006104212A5 JP 2006104212 A5 JP2006104212 A5 JP 2006104212A5 JP 2005363921 A JP2005363921 A JP 2005363921A JP 2005363921 A JP2005363921 A JP 2005363921A JP 2006104212 A5 JP2006104212 A5 JP 2006104212A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- amino acid
- antibody
- kit
- bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 24
- 102000004196 processed proteins & peptides Human genes 0.000 claims 24
- 108090000765 processed proteins & peptides Proteins 0.000 claims 24
- 208000018084 Bone neoplasm Diseases 0.000 claims 16
- 206010006187 Breast cancer Diseases 0.000 claims 15
- 208000026310 Breast neoplasm Diseases 0.000 claims 15
- 125000003275 alpha amino acid group Chemical group 0.000 claims 15
- 108090000623 proteins and genes Proteins 0.000 claims 13
- 206010005949 Bone cancer Diseases 0.000 claims 9
- 241000124008 Mammalia Species 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 8
- 230000014509 gene expression Effects 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 6
- 238000007792 addition Methods 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 5
- 238000012217 deletion Methods 0.000 claims 5
- 230000037430 deletion Effects 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 238000006467 substitution reaction Methods 0.000 claims 5
- 210000000481 breast Anatomy 0.000 claims 4
- 229940127089 cytotoxic agent Drugs 0.000 claims 4
- 210000001519 tissue Anatomy 0.000 claims 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 238000010240 RT-PCR analysis Methods 0.000 claims 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 239000013068 control sample Substances 0.000 claims 2
- 239000002254 cytotoxic agent Substances 0.000 claims 2
- 231100000599 cytotoxic agent Toxicity 0.000 claims 2
- 238000002991 immunohistochemical analysis Methods 0.000 claims 2
- 238000007901 in situ hybridization Methods 0.000 claims 2
- 230000002018 overexpression Effects 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/023328 WO2001016318A2 (en) | 1999-09-01 | 2000-08-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2000/032678 WO2001040466A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/006520 WO2001068848A2 (en) | 2000-03-01 | 2001-02-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/017800 WO2001093983A1 (en) | 2000-06-02 | 2001-06-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/019692 WO2002000690A2 (en) | 2000-06-23 | 2001-06-20 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| PCT/US2001/021066 WO2002008288A2 (en) | 2000-07-20 | 2001-06-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/021735 WO2002008284A2 (en) | 2000-07-20 | 2001-07-09 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002522275A Division JP2004520810A (ja) | 2000-08-24 | 2001-08-23 | 腫瘍の診断と治療のための組成物と方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006104212A JP2006104212A (ja) | 2006-04-20 |
| JP2006104212A5 true JP2006104212A5 (enExample) | 2008-09-18 |
Family
ID=21741709
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005363921A Pending JP2006104212A (ja) | 2000-08-24 | 2005-12-16 | 腫瘍の診断と治療のための組成物と方法 |
| JP2006242365A Expired - Lifetime JP4602954B2 (ja) | 2000-08-24 | 2006-09-07 | インターロイキン−２２ポリペプチド及びそれに結合する抗体の使用 |
| JP2006252159A Pending JP2007077155A (ja) | 2000-08-24 | 2006-09-19 | 腫瘍の診断と治療のための組成物と方法 |
| JP2010177460A Pending JP2011019519A (ja) | 2000-08-24 | 2010-08-06 | インターロイキン−２２ポリペプチド、それをコードする核酸並びに膵臓疾患の治療方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006242365A Expired - Lifetime JP4602954B2 (ja) | 2000-08-24 | 2006-09-07 | インターロイキン−２２ポリペプチド及びそれに結合する抗体の使用 |
| JP2006252159A Pending JP2007077155A (ja) | 2000-08-24 | 2006-09-19 | 腫瘍の診断と治療のための組成物と方法 |
| JP2010177460A Pending JP2011019519A (ja) | 2000-08-24 | 2010-08-06 | インターロイキン−２２ポリペプチド、それをコードする核酸並びに膵臓疾患の治療方法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP2014298A3 (enExample) |
| JP (4) | JP2006104212A (enExample) |
| AT (1) | ATE412009T1 (enExample) |
| AU (1) | AU2006230703A1 (enExample) |
| DE (1) | DE60136281D1 (enExample) |
| ZA (2) | ZA200301205B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0821417A2 (pt) | 2007-12-26 | 2015-06-16 | Biotest Ag | Método para diminuir a adesão de células de estroma a células tumorais que expressam cd138 em células tumorais de um indivíduo em necessidade do mesmo |
| US9221914B2 (en) | 2007-12-26 | 2015-12-29 | Biotest Ag | Agents targeting CD138 and uses thereof |
| SI2242772T1 (sl) | 2007-12-26 | 2015-03-31 | Biotest Ag | Imunokonjugati, ki ciljajo v CD138, in njihova uporaba |
| US20190317098A1 (en) * | 2016-11-24 | 2019-10-17 | Huvet Bio, Inc. | Composition for diagnosis of diseases |
| KR102536314B1 (ko) * | 2018-05-23 | 2023-05-25 | 주식회사 휴벳바이오 | 질환의 진단용 조성물 |
| DK3650037T3 (da) * | 2018-11-07 | 2022-05-02 | Applied Molecular Transport Inc | Indgivelseskonstrukter til transcytose og tilhørende fremgangsmåder |
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-
2001
- 2001-05-30 EP EP08011329A patent/EP2014298A3/en not_active Withdrawn
- 2001-05-30 AT AT01946010T patent/ATE412009T1/de active
- 2001-05-30 DE DE60136281T patent/DE60136281D1/de not_active Expired - Lifetime
- 2001-08-23 EP EP01966255A patent/EP1311668A2/en not_active Withdrawn
-
2003
- 2003-02-13 ZA ZA200301205A patent/ZA200301205B/en unknown
- 2003-02-13 ZA ZA200301202A patent/ZA200301202B/en unknown
-
2005
- 2005-12-16 JP JP2005363921A patent/JP2006104212A/ja active Pending
-
2006
- 2006-09-07 JP JP2006242365A patent/JP4602954B2/ja not_active Expired - Lifetime
- 2006-09-19 JP JP2006252159A patent/JP2007077155A/ja active Pending
- 2006-10-18 AU AU2006230703A patent/AU2006230703A1/en not_active Abandoned
-
2010
- 2010-08-06 JP JP2010177460A patent/JP2011019519A/ja active Pending
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