JP2006036796A5 - - Google Patents

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Publication number
JP2006036796A5
JP2006036796A5 JP2005305080A JP2005305080A JP2006036796A5 JP 2006036796 A5 JP2006036796 A5 JP 2006036796A5 JP 2005305080 A JP2005305080 A JP 2005305080A JP 2005305080 A JP2005305080 A JP 2005305080A JP 2006036796 A5 JP2006036796 A5 JP 2006036796A5
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JP
Japan
Prior art keywords
alkyl
hydrogen
substituted
cancer
composition
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JP2005305080A
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English (en)
Japanese (ja)
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JP4699171B2 (ja
JP2006036796A (ja
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Priority claimed from US10/224,979 external-priority patent/US6800655B2/en
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Publication of JP2006036796A publication Critical patent/JP2006036796A/ja
Publication of JP2006036796A5 publication Critical patent/JP2006036796A5/ja
Application granted granted Critical
Publication of JP4699171B2 publication Critical patent/JP4699171B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2005305080A 2002-08-20 2005-10-19 化学療法薬および化学防御薬としてのインドール−３−カルビノール代謝物の類似物 Expired - Fee Related JP4699171B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/224,979 2002-08-20
US10/224,979 US6800655B2 (en) 2002-08-20 2002-08-20 Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2004531045A Division JP4764629B2 (ja) 2002-08-20 2003-08-15 化学療法薬および化学防御薬としてのインドール−３−カルビノール代謝物の類似物

Publications (3)

Publication Number Publication Date
JP2006036796A JP2006036796A (ja) 2006-02-09
JP2006036796A5 true JP2006036796A5 (enExample) 2006-08-10
JP4699171B2 JP4699171B2 (ja) 2011-06-08

Family

ID=31946289

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2004531045A Expired - Fee Related JP4764629B2 (ja) 2002-08-20 2003-08-15 化学療法薬および化学防御薬としてのインドール−３−カルビノール代謝物の類似物
JP2005305080A Expired - Fee Related JP4699171B2 (ja) 2002-08-20 2005-10-19 化学療法薬および化学防御薬としてのインドール−３−カルビノール代謝物の類似物
JP2010139927A Expired - Fee Related JP5599236B2 (ja) 2002-08-20 2010-06-18 化学療法薬および化学防御薬としてのインドール−３−カルビノール代謝物の類似物

Family Applications Before (1)

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JP2004531045A Expired - Fee Related JP4764629B2 (ja) 2002-08-20 2003-08-15 化学療法薬および化学防御薬としてのインドール−３−カルビノール代謝物の類似物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010139927A Expired - Fee Related JP5599236B2 (ja) 2002-08-20 2010-06-18 化学療法薬および化学防御薬としてのインドール−３−カルビノール代謝物の類似物

Country Status (8)

Country Link
US (4) US6800655B2 (enExample)
EP (2) EP1530572B1 (enExample)
JP (3) JP4764629B2 (enExample)
AT (1) ATE411317T1 (enExample)
AU (1) AU2003263878A1 (enExample)
CA (1) CA2496203C (enExample)
DE (1) DE60324155D1 (enExample)
WO (1) WO2004018475A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800655B2 (en) * 2002-08-20 2004-10-05 Sri International Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents
CA2565721C (en) * 2004-05-06 2015-10-06 Bioresponse, L.L.C. Diindolymethane formulations for the treatment of leiomyomas
US20060100264A1 (en) * 2004-11-06 2006-05-11 Bjeldanes Leonard F 3,3'-Diindolylmethane immune activating compositions
US7989486B2 (en) * 2004-12-30 2011-08-02 Bioresponse, L.L.C. Use of diindolylmethane-related indoles for the treatment and prevention of respiratory syncytial virus associated conditions
EP1845974A1 (en) 2005-01-21 2007-10-24 Astex Therapeutics Limited Pharmaceutical compounds
JP2008545663A (ja) * 2005-05-27 2008-12-18 クイーンズ ユニバーシティ アット キングストン タンパク質フォールディング障害の治療
CN1807413B (zh) * 2005-09-28 2010-05-05 中国医学科学院医药生物技术研究所 咔唑磺酰胺衍生物及其制备方法
EP2014652B1 (en) 2006-04-18 2014-08-06 Nippon Chemiphar Co., Ltd. Activating agent for peroxisome proliferator activated receptor
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
WO2008057253A2 (en) 2006-10-27 2008-05-15 Bioresponse, L.L.C. Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
US7807705B2 (en) * 2007-05-18 2010-10-05 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
US20100292316A1 (en) * 2007-07-18 2010-11-18 Research Development Foundation Improved therapeutic methods and compositions comprising chroman ring compounds
MX2010011252A (es) * 2008-04-15 2010-11-30 Nippon Chemiphar Co Activador para el receptor activado por el proliferador de peroxisoma.
EP2326327B1 (en) * 2008-09-17 2016-03-23 SRI International Analogs of indole-3-carbinol and their use as agents against infection
KR101477613B1 (ko) * 2009-03-31 2014-12-30 롬엔드하스전자재료코리아유한회사 신규한 유기 전자재료용 화합물 및 이를 포함하는 유기 전자 소자
WO2010118339A2 (en) * 2009-04-09 2010-10-14 University Of Kansas Formulations of indole-3-carbinol derived antitumor agents with increased oral bioavailability
US20110092517A1 (en) * 2009-08-14 2011-04-21 Cerenis Therapeutics S.A. & Nippon Chemiphar Co., Ltd. Use of PPAR Delta Ligands for the Treatment or Prevention of Inflammation or Energy Metabolism/Production Related Diseases
US8153680B2 (en) * 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents
DE102009052428A1 (de) * 2009-11-10 2011-05-12 Merck Patent Gmbh Verbindung für elektronische Vorrichtungen
WO2011140164A1 (en) * 2010-05-06 2011-11-10 Merck Sharp & Dohme Corp. Aza-indole derivatives useful as modulators of faah
EP2694057B1 (en) * 2011-04-01 2019-06-05 SRI International Lipoxygenase inhibitors
WO2015042170A1 (en) 2013-09-17 2015-03-26 Wayne State University Compositions and uses of combinations of dim-related indoles and selected anti-androgen compounds
CN104030964B (zh) * 2014-06-05 2016-06-29 天津科技大学 双吲哚类化合物及合成方法
US9969686B2 (en) * 2014-08-05 2018-05-15 Wisconsin Alumni Research Foundation Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them
WO2016164770A1 (en) 2015-04-10 2016-10-13 Bioresponse, L.L.C. Self-emulsifying formulations of dim-related indoles
WO2017011920A1 (en) * 2015-07-22 2017-01-26 The Royal Institution For The Advancement Of Learning/Mcgill University Compounds and uses thereof in the treatment of cancers and other medical conditions
CN105218552B (zh) * 2015-09-30 2018-02-27 中国人民解放军军事医学科学院野战输血研究所 一种取代苯基二氢吲哚咔唑衍生物及其制备方法与应用
CN110698654B (zh) * 2018-07-10 2021-04-02 中国科学院长春应用化学研究所 基于三聚吲哚的超支化共轭聚电解质及其制备方法和用途
WO2026010962A1 (en) 2024-07-01 2026-01-08 Otsuka America Pharmaceutical, Inc. 3-pyrrolidine-indole derivative compounds useful for the treatment of disorders and methods related thereto

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US5206377A (en) * 1991-12-05 1993-04-27 Whitby Research, Inc. Compounds useful as antiproliferative agents
US5407102A (en) * 1994-02-15 1995-04-18 Freudinger; Mark J. Apparatus for dispensing a quantity of flowable material
US5948808A (en) * 1997-03-07 1999-09-07 The Texas A&M University System Indole-3-carbinol, diindolylmethane and substituted analogs as antiestrogens
US5843607A (en) * 1997-10-02 1998-12-01 Xerox Corporation Indolocarbazole photoconductors
US5942340A (en) * 1997-10-02 1999-08-24 Xerox Corporation Indolocarbazole electroluminescent devices
SK16352000A3 (sk) * 1998-05-04 2002-07-02 Zentaris Ag Indolové deriváty, spôsob ich výroby, ich použitie na liečivá obsahujúce tieto zlúčeniny
JP2002520315A (ja) * 1998-07-08 2002-07-09 ハーバー ブランチ オーシャノグラフィック インスティテューション インク． ビスインドール誘導体および抗炎症剤としてのそれらの使用
IT1317926B1 (it) 2000-11-03 2003-07-15 Sigma Tau Ind Farmaceuti Derivati triciclici dell'indolo ad attivita' antiangiogenica.
IT1317925B1 (it) 2000-11-03 2003-07-15 Sigma Tau Ind Farmaceuti Bis-eterocicli ad attivita' antitumorale e chemosensibilizzante.
JP2003346530A (ja) 2002-05-23 2003-12-05 Nippon Sheet Glass Co Ltd 面状光源装置および画像読み取り装置
US6800655B2 (en) * 2002-08-20 2004-10-05 Sri International Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents

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