JP2005538093A - 抗血管形成療法のための、テトラポリアンモニウムテトラチオモリブデートおよび関連化合物 - Google Patents

抗血管形成療法のための、テトラポリアンモニウムテトラチオモリブデートおよび関連化合物 Download PDF

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Publication number
JP2005538093A
JP2005538093A JP2004523295A JP2004523295A JP2005538093A JP 2005538093 A JP2005538093 A JP 2005538093A JP 2004523295 A JP2004523295 A JP 2004523295A JP 2004523295 A JP2004523295 A JP 2004523295A JP 2005538093 A JP2005538093 A JP 2005538093A
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JP
Japan
Prior art keywords
copper
tetrathiomolybdate
compound
composition
animal
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JP2004523295A
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Japanese (ja)
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JP2005538093A5 (enExample
Inventor
ジョージ ジェイ． ブレワー，
ソフィア ディー． マラジバー，
ディミトリ コウコウバニス，
Original Assignee
ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン
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Publication of JP2005538093A publication Critical patent/JP2005538093A/ja
Publication of JP2005538093A5 publication Critical patent/JP2005538093A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2004523295A 2002-07-23 2003-07-23 抗血管形成療法のための、テトラポリアンモニウムテトラチオモリブデートおよび関連化合物 Pending JP2005538093A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39780402P 2002-07-23 2002-07-23
PCT/US2003/022914 WO2004009072A2 (en) 2002-07-23 2003-07-23 Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies

Publications (2)

Publication Number Publication Date
JP2005538093A true JP2005538093A (ja) 2005-12-15
JP2005538093A5 JP2005538093A5 (enExample) 2006-09-07

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ID=30771119

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JP2004523295A Pending JP2005538093A (ja) 2002-07-23 2003-07-23 抗血管形成療法のための、テトラポリアンモニウムテトラチオモリブデートおよび関連化合物

Country Status (16)

Country Link
US (1) US7888389B2 (enExample)
EP (1) EP1539131A4 (enExample)
JP (1) JP2005538093A (enExample)
KR (1) KR20050025976A (enExample)
CN (1) CN1688303A (enExample)
AU (1) AU2003261222B2 (enExample)
BR (1) BR0312845A (enExample)
CA (1) CA2493341A1 (enExample)
EA (1) EA008683B1 (enExample)
GE (1) GEP20074270B (enExample)
IL (1) IL166385A0 (enExample)
MX (1) MXPA05000875A (enExample)
NO (1) NO20050902L (enExample)
NZ (1) NZ537896A (enExample)
WO (1) WO2004009072A2 (enExample)
ZA (1) ZA200501162B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007516234A (ja) * 2003-05-27 2007-06-21 アテニュオン，リミティド ライアビリティー カンパニー チオタングステン酸（塩）アナログ及びその使用
JP2021505655A (ja) * 2017-12-04 2021-02-18 アレクシオン・ファーマ・インターナショナル・オペレーションズ・アンリミテッド・カンパニー ウィルソン病を治療するためのビスコリンテトラチオモリブデート

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EP1487431B1 (en) * 2002-03-08 2012-05-02 PhilERA New Zealand Limited Preventing and/or treating cardiovascular disease and/or associated heart failure
US20070292533A1 (en) * 2002-05-24 2007-12-20 Regents Of The University Of Michigan Copper lowering treatment of autoimmune diseases
US20070248689A1 (en) * 2002-05-24 2007-10-25 Regents Of The University Of Michigan Copper lowering treatment of inflammatory and fibrotic diseases
US7189865B2 (en) * 2002-07-23 2007-03-13 Attenuon, Llc Thiomolybdate analogues and uses thereof
MXPA05000875A (es) 2002-07-23 2005-09-30 Univ Michigan Tetratiomolibdato de tetrapropilamonio y compuestos relacionados para terapias anti-angiogenicas.
US20060100278A1 (en) 2002-08-20 2006-05-11 Cooper Garth J S Dosage forms and related therapies
RU2002128364A (ru) * 2002-10-23 2004-04-27 Институт нефтехимического синтеза РАН им. А.В. Топчиева Способ получения присадки к смазочным материалам (варианты)
EP1729784A1 (en) * 2004-02-23 2006-12-13 Attenuon, LLC Formulations of thiomolybdate or thiotungstate compounds and uses thereof
WO2005083107A2 (en) * 2004-02-24 2005-09-09 Attenuon Llp Inhibition of superoxide dismutase by tetrathiomolybdate: identification of new anti-angiogenic and antitumor agents
WO2006027705A2 (en) 2004-07-19 2006-03-16 Protemix Corporation Limited Synthesis of triethylenetetramines
US20060134708A1 (en) * 2004-10-14 2006-06-22 Northwestern University Detection and treatment of renal cancer
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WO2009009622A2 (en) * 2007-07-09 2009-01-15 Pipex Pharmaceuticals, Inc. Pharmaceutical compositions, including attm, and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases
US20100312139A1 (en) * 2009-06-04 2010-12-09 Board Of Regents Of The University Of Texas System Method for Identifying Mammals at Risk for Elevated intracranial Pressure
WO2011071995A2 (en) 2009-12-08 2011-06-16 Case Western Reserve University Compounds and methods of treating ocular disorders
US20160220500A1 (en) * 2014-11-14 2016-08-04 Kent State University Targeting Intracellular Copper Ions for Inhibiting Angiogenesis Using Nanoparticles of Ternary Inorganic Metal Sulfide M1M2S4 (M1, independently, is Mg, Ca, Mn, Fe, or Zn; M2 = Mo or W) Compounds to Treat Metastatic Cancer
US10874624B2 (en) 2015-02-03 2020-12-29 Kadmon Pharmaceuticals, Llc Stable trientine formulations
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
JP2023549037A (ja) 2020-10-07 2023-11-22 シーティーアイ バスキュラー アーゲー 生物活性型に変換可能なデバイスおよび関連する方法

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MXPA05000875A (es) 2002-07-23 2005-09-30 Univ Michigan Tetratiomolibdato de tetrapropilamonio y compuestos relacionados para terapias anti-angiogenicas.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007516234A (ja) * 2003-05-27 2007-06-21 アテニュオン，リミティド ライアビリティー カンパニー チオタングステン酸（塩）アナログ及びその使用
JP2021505655A (ja) * 2017-12-04 2021-02-18 アレクシオン・ファーマ・インターナショナル・オペレーションズ・アンリミテッド・カンパニー ウィルソン病を治療するためのビスコリンテトラチオモリブデート
JP2023075247A (ja) * 2017-12-04 2023-05-30 アレクシオン・ファーマ・インターナショナル・オペレーションズ・アンリミテッド・カンパニー ウィルソン病を治療するためのビスコリンテトラチオモリブデート

Also Published As

Publication number Publication date
US20040259945A1 (en) 2004-12-23
EA008683B1 (ru) 2007-06-29
EP1539131A2 (en) 2005-06-15
BR0312845A (pt) 2005-06-07
EA200500244A1 (ru) 2005-12-29
IL166385A0 (en) 2006-01-16
KR20050025976A (ko) 2005-03-14
CN1688303A (zh) 2005-10-26
GEP20074270B (en) 2007-12-25
NZ537896A (en) 2007-12-21
EP1539131A4 (en) 2009-07-08
MXPA05000875A (es) 2005-09-30
AU2003261222B2 (en) 2009-07-09
US7888389B2 (en) 2011-02-15
WO2004009072A3 (en) 2004-04-08
ZA200501162B (en) 2005-09-05
CA2493341A1 (en) 2004-01-29
WO2004009072B1 (en) 2004-07-08
NO20050902L (no) 2005-04-19
WO2004009072A2 (en) 2004-01-29
AU2003261222A1 (en) 2004-02-09

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