IL166385A0 - Tetrapropylammonium terathiomolybodate and relatedcompounds for anti-angiogenic therapies - Google Patents
Tetrapropylammonium terathiomolybodate and relatedcompounds for anti-angiogenic therapiesInfo
- Publication number
- IL166385A0 IL166385A0 IL16638505A IL16638505A IL166385A0 IL 166385 A0 IL166385 A0 IL 166385A0 IL 16638505 A IL16638505 A IL 16638505A IL 16638505 A IL16638505 A IL 16638505A IL 166385 A0 IL166385 A0 IL 166385A0
- Authority
- IL
- Israel
- Prior art keywords
- terathiomolybodate
- relatedcompounds
- tetrapropylammonium
- angiogenic therapies
- angiogenic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39780402P | 2002-07-23 | 2002-07-23 | |
| PCT/US2003/022914 WO2004009072A2 (en) | 2002-07-23 | 2003-07-23 | Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL166385A0 true IL166385A0 (en) | 2006-01-16 |
Family
ID=30771119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16638505A IL166385A0 (en) | 2002-07-23 | 2005-01-20 | Tetrapropylammonium terathiomolybodate and relatedcompounds for anti-angiogenic therapies |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7888389B2 (enExample) |
| EP (1) | EP1539131A4 (enExample) |
| JP (1) | JP2005538093A (enExample) |
| KR (1) | KR20050025976A (enExample) |
| CN (1) | CN1688303A (enExample) |
| AU (1) | AU2003261222B2 (enExample) |
| BR (1) | BR0312845A (enExample) |
| CA (1) | CA2493341A1 (enExample) |
| EA (1) | EA008683B1 (enExample) |
| GE (1) | GEP20074270B (enExample) |
| IL (1) | IL166385A0 (enExample) |
| MX (1) | MXPA05000875A (enExample) |
| NO (1) | NO20050902L (enExample) |
| NZ (1) | NZ537896A (enExample) |
| WO (1) | WO2004009072A2 (enExample) |
| ZA (1) | ZA200501162B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6703050B1 (en) | 1998-09-04 | 2004-03-09 | The Regents Of The University Of Michigan | Methods and compositions for the prevention or treatment of cancer |
| WO2000018392A1 (en) * | 1998-09-25 | 2000-04-06 | Glycox Corporation Limited | Fructosamine oxidase: antagonists and inhibitors |
| EP1487431B1 (en) * | 2002-03-08 | 2012-05-02 | PhilERA New Zealand Limited | Preventing and/or treating cardiovascular disease and/or associated heart failure |
| US20070292533A1 (en) * | 2002-05-24 | 2007-12-20 | Regents Of The University Of Michigan | Copper lowering treatment of autoimmune diseases |
| US20070248689A1 (en) * | 2002-05-24 | 2007-10-25 | Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
| US7189865B2 (en) * | 2002-07-23 | 2007-03-13 | Attenuon, Llc | Thiomolybdate analogues and uses thereof |
| MXPA05000875A (es) | 2002-07-23 | 2005-09-30 | Univ Michigan | Tetratiomolibdato de tetrapropilamonio y compuestos relacionados para terapias anti-angiogenicas. |
| US20060100278A1 (en) | 2002-08-20 | 2006-05-11 | Cooper Garth J S | Dosage forms and related therapies |
| RU2002128364A (ru) * | 2002-10-23 | 2004-04-27 | Институт нефтехимического синтеза РАН им. А.В. Топчиева | Способ получения присадки к смазочным материалам (варианты) |
| EP1633310A4 (en) * | 2003-05-27 | 2006-10-18 | Attenuon Llc | THIOWOLFRAM ANALOGUE AND ITS USES |
| EP1729784A1 (en) * | 2004-02-23 | 2006-12-13 | Attenuon, LLC | Formulations of thiomolybdate or thiotungstate compounds and uses thereof |
| WO2005083107A2 (en) * | 2004-02-24 | 2005-09-09 | Attenuon Llp | Inhibition of superoxide dismutase by tetrathiomolybdate: identification of new anti-angiogenic and antitumor agents |
| WO2006027705A2 (en) | 2004-07-19 | 2006-03-16 | Protemix Corporation Limited | Synthesis of triethylenetetramines |
| US20060134708A1 (en) * | 2004-10-14 | 2006-06-22 | Northwestern University | Detection and treatment of renal cancer |
| EP2117315A1 (en) * | 2007-02-21 | 2009-11-18 | SSV Therapeutics, Inc. | Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids |
| WO2009009622A2 (en) * | 2007-07-09 | 2009-01-15 | Pipex Pharmaceuticals, Inc. | Pharmaceutical compositions, including attm, and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases |
| US20100312139A1 (en) * | 2009-06-04 | 2010-12-09 | Board Of Regents Of The University Of Texas System | Method for Identifying Mammals at Risk for Elevated intracranial Pressure |
| WO2011071995A2 (en) | 2009-12-08 | 2011-06-16 | Case Western Reserve University | Compounds and methods of treating ocular disorders |
| US20160220500A1 (en) * | 2014-11-14 | 2016-08-04 | Kent State University | Targeting Intracellular Copper Ions for Inhibiting Angiogenesis Using Nanoparticles of Ternary Inorganic Metal Sulfide M1M2S4 (M1, independently, is Mg, Ca, Mn, Fe, or Zn; M2 = Mo or W) Compounds to Treat Metastatic Cancer |
| US10874624B2 (en) | 2015-02-03 | 2020-12-29 | Kadmon Pharmaceuticals, Llc | Stable trientine formulations |
| AU2018379255B2 (en) * | 2017-12-04 | 2024-10-17 | Alexion Pharma International Operations Unlimited Company | Bis-choline tetrathiomolybdate for treating Wilson Disease |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| JP2023549037A (ja) | 2020-10-07 | 2023-11-22 | シーティーアイ バスキュラー アーゲー | 生物活性型に変換可能なデバイスおよび関連する方法 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909541A (en) | 1955-01-07 | 1959-10-20 | Inst Francais Du Petrole | Nitrogenous thiomolybdates |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4343746A (en) | 1980-12-10 | 1982-08-10 | Gulf Research & Development Company | Quaternary ammonium thiomolybdates |
| US4762705A (en) | 1981-11-10 | 1988-08-09 | Adolf W. Schwimmer | Cancer therapy with interferon |
| US4952607A (en) | 1982-05-27 | 1990-08-28 | International Copper Research Association, Inc. | Copper complex for treating cancer |
| US4430443A (en) | 1982-07-20 | 1984-02-07 | Exxon Research And Engineering Co. | Supported carbon-containing molybdenum and tungsten sulfide catalysts, their preparation and use |
| US4766226A (en) | 1984-02-01 | 1988-08-23 | Smithkline Beckman Corporation | Antitumor pharmaceutical compositions and methods for treating tumors employing α,ω-bis(disubstitutedphosphino)hydrocarbon derivatives or [α, ω-bis(disubstitutedphosphino)hydrocarbon] di |
| WO1986003677A1 (en) | 1984-12-18 | 1986-07-03 | David Rubin | Anti-tumor compositions containing the reaction product of a cytotoxic aldehyde with penicillamine and method of use thereof |
| GB8504253D0 (en) | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
| US4604278A (en) * | 1985-05-17 | 1986-08-05 | Gte Products Corporation | Production of ammonium tetrathiomolybdate |
| US4678667A (en) | 1985-07-02 | 1987-07-07 | 501 Regents of the University of California | Macrocyclic bifunctional chelating agents |
| US5776093A (en) | 1985-07-05 | 1998-07-07 | Immunomedics, Inc. | Method for imaging and treating organs and tissues |
| US5162231A (en) | 1989-10-25 | 1992-11-10 | Cole Dean A | Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung |
| US5057302A (en) | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
| DE3815221C2 (de) | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| US5385933A (en) | 1989-02-27 | 1995-01-31 | The United States Of America As Represented By The Department Of Health And Human Services | Method for the treatment of cancer by use of the copper complex of S-(methylthio)-DL-homocysteine or the L-enantiomorph thereof |
| US5100885A (en) | 1989-08-01 | 1992-03-31 | Johnson Matthey, Inc. | Copper radiosensitizers |
| US5443816A (en) | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
| MX172248B (es) | 1989-12-20 | 1993-12-09 | Univ Mexico | Procedimiento para la obtencion de nuevos complejos aminoacidatos de cobre mixtos a base de fenantrolinas feniladas como agentes anticancerigenos |
| US5972922A (en) | 1990-06-11 | 1999-10-26 | Alcon Laboratories, Inc. | Steroids which inhibit angiogenesis |
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| CA2138538A1 (en) | 1992-06-19 | 1994-01-06 | Dimitris Skalkos | Production and use of imines of porphyrins |
| US5629327A (en) | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
| US5565491A (en) | 1994-01-31 | 1996-10-15 | Bristol-Myers Squibb Company | Use of phosphotyrosine phospatase inhibitors for controlling cellular proliferation |
| US5753230A (en) | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| US5639725A (en) | 1994-04-26 | 1997-06-17 | Children's Hospital Medical Center Corp. | Angiostatin protein |
| US5563132A (en) | 1994-06-21 | 1996-10-08 | Bodaness; Richard S. | Two-step cancer treatment method |
| US5583153A (en) | 1994-10-06 | 1996-12-10 | Regents Of The University Of California | Use of taxol in the treatment of rheumatoid arthritis |
| US5527533A (en) | 1994-10-27 | 1996-06-18 | Board Of Trustees Of The University Of Illinois | Method of retarding and ameliorating central nervous system and eye damage |
| ATE186222T1 (de) | 1995-03-14 | 1999-11-15 | Siemens Ag | Ultraschallzerstäuber mit abnehmbarer präzisionsdosiereinheit |
| ES2177771T3 (es) | 1995-03-14 | 2002-12-16 | Siemens Ag | Dispositivo atomizador ultrasonico con unidad desmontable de dosificacion de precision. |
| US5639757A (en) | 1995-05-23 | 1997-06-17 | Pfizer Inc. | 4-aminopyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors |
| US5954047A (en) | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
| IL141550A0 (en) | 1998-09-04 | 2002-03-10 | Univ Michigan | Methods and compositions for the prevention or treatment of cancer |
| US6703050B1 (en) | 1998-09-04 | 2004-03-09 | The Regents Of The University Of Michigan | Methods and compositions for the prevention or treatment of cancer |
| SI1107795T1 (en) | 1998-09-04 | 2003-06-30 | The Regents Of The University Of Michigan | Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis |
| JP2005504060A (ja) * | 2001-08-24 | 2005-02-10 | メイン・メデイカル・センター・リサーチ・インステイテユート | 銅依存性の非伝統的前炎症性サイトカイン輸送およびそれに関連する方法、組成物およびキット |
| US6855340B2 (en) | 2002-05-24 | 2005-02-15 | Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
| MXPA05000875A (es) | 2002-07-23 | 2005-09-30 | Univ Michigan | Tetratiomolibdato de tetrapropilamonio y compuestos relacionados para terapias anti-angiogenicas. |
| US7189865B2 (en) * | 2002-07-23 | 2007-03-13 | Attenuon, Llc | Thiomolybdate analogues and uses thereof |
-
2003
- 2003-07-23 MX MXPA05000875A patent/MXPA05000875A/es unknown
- 2003-07-23 AU AU2003261222A patent/AU2003261222B2/en not_active Expired - Fee Related
- 2003-07-23 BR BR0312845-8A patent/BR0312845A/pt not_active Application Discontinuation
- 2003-07-23 CN CNA03820746XA patent/CN1688303A/zh active Pending
- 2003-07-23 EP EP03765921A patent/EP1539131A4/en not_active Withdrawn
- 2003-07-23 GE GEAP20038654A patent/GEP20074270B/en unknown
- 2003-07-23 KR KR1020057001226A patent/KR20050025976A/ko not_active Ceased
- 2003-07-23 JP JP2004523295A patent/JP2005538093A/ja active Pending
- 2003-07-23 WO PCT/US2003/022914 patent/WO2004009072A2/en not_active Ceased
- 2003-07-23 US US10/625,839 patent/US7888389B2/en not_active Expired - Lifetime
- 2003-07-23 EA EA200500244A patent/EA008683B1/ru not_active IP Right Cessation
- 2003-07-23 CA CA002493341A patent/CA2493341A1/en not_active Abandoned
- 2003-07-23 NZ NZ537896A patent/NZ537896A/en unknown
-
2005
- 2005-01-20 IL IL16638505A patent/IL166385A0/xx unknown
- 2005-02-09 ZA ZA200501162A patent/ZA200501162B/xx unknown
- 2005-02-18 NO NO20050902A patent/NO20050902L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20040259945A1 (en) | 2004-12-23 |
| EA008683B1 (ru) | 2007-06-29 |
| EP1539131A2 (en) | 2005-06-15 |
| BR0312845A (pt) | 2005-06-07 |
| EA200500244A1 (ru) | 2005-12-29 |
| KR20050025976A (ko) | 2005-03-14 |
| CN1688303A (zh) | 2005-10-26 |
| GEP20074270B (en) | 2007-12-25 |
| JP2005538093A (ja) | 2005-12-15 |
| NZ537896A (en) | 2007-12-21 |
| EP1539131A4 (en) | 2009-07-08 |
| MXPA05000875A (es) | 2005-09-30 |
| AU2003261222B2 (en) | 2009-07-09 |
| US7888389B2 (en) | 2011-02-15 |
| WO2004009072A3 (en) | 2004-04-08 |
| ZA200501162B (en) | 2005-09-05 |
| CA2493341A1 (en) | 2004-01-29 |
| WO2004009072B1 (en) | 2004-07-08 |
| NO20050902L (no) | 2005-04-19 |
| WO2004009072A2 (en) | 2004-01-29 |
| AU2003261222A1 (en) | 2004-02-09 |
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