JP2005538045A5 - - Google Patents
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- Publication number
- JP2005538045A5 JP2005538045A5 JP2003584115A JP2003584115A JP2005538045A5 JP 2005538045 A5 JP2005538045 A5 JP 2005538045A5 JP 2003584115 A JP2003584115 A JP 2003584115A JP 2003584115 A JP2003584115 A JP 2003584115A JP 2005538045 A5 JP2005538045 A5 JP 2005538045A5
- Authority
- JP
- Japan
- Prior art keywords
- fibrinogen
- lmw
- hmw
- vivo
- variant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000008946 Fibrinogen Human genes 0.000 claims 5
- 108010049003 Fibrinogen Proteins 0.000 claims 5
- 229940012952 fibrinogen Drugs 0.000 claims 4
- 239000002323 fibrinogen variant Substances 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 206010048591 Post thrombotic syndrome Diseases 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1020426A NL1020426C2 (nl) | 2002-04-18 | 2002-04-18 | Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen. |
| NL1020426 | 2002-04-18 | ||
| PCT/NL2003/000293 WO2003087160A1 (en) | 2002-04-18 | 2003-04-07 | Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010088946A Division JP5395726B2 (ja) | 2002-04-18 | 2010-04-07 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005538045A JP2005538045A (ja) | 2005-12-15 |
| JP2005538045A5 true JP2005538045A5 (enExample) | 2006-06-01 |
| JP5083928B2 JP5083928B2 (ja) | 2012-11-28 |
Family
ID=29244993
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003584115A Expired - Lifetime JP5083928B2 (ja) | 2002-04-18 | 2003-04-07 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
| JP2010088946A Expired - Lifetime JP5395726B2 (ja) | 2002-04-18 | 2010-04-07 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
| JP2010106630A Expired - Lifetime JP5248547B2 (ja) | 2002-04-18 | 2010-05-06 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010088946A Expired - Lifetime JP5395726B2 (ja) | 2002-04-18 | 2010-04-07 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
| JP2010106630A Expired - Lifetime JP5248547B2 (ja) | 2002-04-18 | 2010-05-06 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7867519B2 (enExample) |
| EP (1) | EP1495051B1 (enExample) |
| JP (3) | JP5083928B2 (enExample) |
| AT (1) | ATE403679T1 (enExample) |
| AU (1) | AU2003230455A1 (enExample) |
| CA (1) | CA2482893C (enExample) |
| DE (1) | DE60322687D1 (enExample) |
| DK (1) | DK1495051T3 (enExample) |
| NL (1) | NL1020426C2 (enExample) |
| WO (1) | WO2003087160A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004067704A2 (en) | 2003-01-30 | 2004-08-12 | Prochon Biotech Ltd. | Freeze-dried fibrin matrices and methods for preparation thereof |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US7335508B2 (en) | 2004-07-22 | 2008-02-26 | Prochon Biotech Ltd. | Porous plasma protein matrices and methods for preparation thereof |
| US20090319045A1 (en) | 2004-10-12 | 2009-12-24 | Truncale Katherine G | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| US8921109B2 (en) | 2005-09-19 | 2014-12-30 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| EP2106263B1 (en) | 2007-01-04 | 2016-12-21 | Hepacore Ltd. | Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| MX2011000281A (es) | 2008-07-09 | 2011-04-26 | Profibrix Bv | Fibrinogeno recombinante. |
| ES2524886T3 (es) * | 2010-01-08 | 2014-12-15 | Profibrix Bv | Preparados de fibrinógeno enriquecidos en fibrinógeno con una cadena alfa extendida |
| WO2011083154A1 (en) * | 2010-01-08 | 2011-07-14 | Profibrix Bv | Dry powder fibrin sealant |
| WO2012140650A2 (en) | 2011-04-12 | 2012-10-18 | Hepacore Ltd. | Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof |
| US8999376B2 (en) | 2012-02-03 | 2015-04-07 | Xcede Technologies, Inc. | Tissue patch |
| KR101567053B1 (ko) | 2013-09-30 | 2015-11-09 | 한국원자력의학원 | 방사선 피폭에 의한 간 손상 예측용 바이오마커 및 그 예측방법 |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| WO2017027378A1 (en) | 2015-08-07 | 2017-02-16 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
| US9540548B1 (en) | 2015-08-07 | 2017-01-10 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
| US9833538B2 (en) | 2015-08-07 | 2017-12-05 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69132918T2 (de) * | 1990-11-27 | 2002-10-31 | American National Red Cross, Washington | Gewebeabdeckung und wachstumsfaktor enthaltende verbindungen zur förderung beschleunigter wundheilung |
| AU709134B2 (en) * | 1994-05-02 | 1999-08-19 | E.R. Squibb & Sons, Inc. | Recombinant fibrin chains, fibrin and fibrin-homologs |
| CA2207992A1 (en) * | 1995-01-16 | 1996-07-25 | Genevieve Krack | Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions |
| US6037457A (en) * | 1997-01-31 | 2000-03-14 | The University Of North Carolina At Chapel Hill | Method for recombinant fibrinogen production |
| WO1998055140A1 (en) * | 1997-06-05 | 1998-12-10 | Omrix Biopharmaceuticals S.A. | Fibrinogen concentrate from human plasma |
| US6946140B1 (en) * | 1999-02-09 | 2005-09-20 | The Research Foundation Of State University Of New York | Methods and compositions for enhancing fibroblast migration |
| AU4351000A (en) * | 1999-04-15 | 2000-11-02 | Research Foundation Of State University Of New York, The | Cellular matrix system and use thereof |
| AU771557B2 (en) * | 1999-06-01 | 2004-03-25 | Vivolution A/S | Prevention of post surgical adhesions using a fibrin monomer sealant |
-
2002
- 2002-04-18 NL NL1020426A patent/NL1020426C2/nl not_active IP Right Cessation
-
2003
- 2003-04-07 US US10/511,700 patent/US7867519B2/en not_active Expired - Lifetime
- 2003-04-07 AT AT03723513T patent/ATE403679T1/de active
- 2003-04-07 DE DE60322687T patent/DE60322687D1/de not_active Expired - Lifetime
- 2003-04-07 CA CA2482893A patent/CA2482893C/en not_active Expired - Lifetime
- 2003-04-07 AU AU2003230455A patent/AU2003230455A1/en not_active Abandoned
- 2003-04-07 EP EP03723513A patent/EP1495051B1/en not_active Expired - Lifetime
- 2003-04-07 WO PCT/NL2003/000293 patent/WO2003087160A1/en not_active Ceased
- 2003-04-07 JP JP2003584115A patent/JP5083928B2/ja not_active Expired - Lifetime
- 2003-04-07 DK DK03723513T patent/DK1495051T3/da active
-
2010
- 2010-04-07 JP JP2010088946A patent/JP5395726B2/ja not_active Expired - Lifetime
- 2010-05-06 JP JP2010106630A patent/JP5248547B2/ja not_active Expired - Lifetime
- 2010-11-24 US US12/953,941 patent/US20110071083A1/en not_active Abandoned
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