NL1020426C2 - Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen. - Google Patents
Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen. Download PDFInfo
- Publication number
- NL1020426C2 NL1020426C2 NL1020426A NL1020426A NL1020426C2 NL 1020426 C2 NL1020426 C2 NL 1020426C2 NL 1020426 A NL1020426 A NL 1020426A NL 1020426 A NL1020426 A NL 1020426A NL 1020426 C2 NL1020426 C2 NL 1020426C2
- Authority
- NL
- Netherlands
- Prior art keywords
- fibrinogen
- lmw
- hmw
- fibrin
- fibrin matrix
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/046—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1020426A NL1020426C2 (nl) | 2002-04-18 | 2002-04-18 | Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen. |
| JP2003584115A JP5083928B2 (ja) | 2002-04-18 | 2003-04-07 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
| AT03723513T ATE403679T1 (de) | 2002-04-18 | 2003-04-07 | Veränderung von eigenschaften einer fibrinmatrix in bezug auf das zellwachstum |
| DK03723513T DK1495051T3 (da) | 2002-04-18 | 2003-04-07 | Modifikation af egenskaberne af en fibrinmatrix med hensyn til vækst og indvækst af celler |
| DE60322687T DE60322687D1 (de) | 2002-04-18 | 2003-04-07 | Veränderung von eigenschaften einer fibrinmatrix in bezug auf das zellwachstum |
| US10/511,700 US7867519B2 (en) | 2002-04-18 | 2003-04-07 | Method for the acceleration or deceleration of angiogenesis using fibrin matrix formed from increased or decreased HMW/LMW fibrinogen ratio |
| EP03723513A EP1495051B1 (en) | 2002-04-18 | 2003-04-07 | Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells |
| PCT/NL2003/000293 WO2003087160A1 (en) | 2002-04-18 | 2003-04-07 | Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells |
| CA2482893A CA2482893C (en) | 2002-04-18 | 2003-04-07 | Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells |
| AU2003230455A AU2003230455A1 (en) | 2002-04-18 | 2003-04-07 | Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells |
| JP2010088946A JP5395726B2 (ja) | 2002-04-18 | 2010-04-07 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
| JP2010106630A JP5248547B2 (ja) | 2002-04-18 | 2010-05-06 | 細胞の成長及び内方成長に関してフィブリンマトリックスの特性の修飾 |
| US12/953,941 US20110071083A1 (en) | 2002-04-18 | 2010-11-24 | Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells |
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| NL1020426 | 2002-04-18 | ||
| NL1020426A NL1020426C2 (nl) | 2002-04-18 | 2002-04-18 | Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen. |
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| NL1020426C2 true NL1020426C2 (nl) | 2003-10-21 |
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| NL (1) | NL1020426C2 (enExample) |
| WO (1) | WO2003087160A1 (enExample) |
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| CA2514474C (en) | 2003-01-30 | 2014-05-06 | Avner Yayon | Freeze-dried fibrin matrices and methods for preparation thereof |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US7335508B2 (en) | 2004-07-22 | 2008-02-26 | Prochon Biotech Ltd. | Porous plasma protein matrices and methods for preparation thereof |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| EP1926459B1 (en) | 2005-09-19 | 2015-01-07 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| EP2106263B1 (en) | 2007-01-04 | 2016-12-21 | Hepacore Ltd. | Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| WO2009111069A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| JP5819725B2 (ja) | 2008-07-09 | 2015-11-24 | プロフィブリックス ビーブイ | 組換えフィブリノゲン |
| CN102724968A (zh) * | 2010-01-08 | 2012-10-10 | 普罗菲布瑞克斯公司 | 干粉血纤蛋白密封剂 |
| AU2011204557B2 (en) * | 2010-01-08 | 2014-08-28 | Mallinckrodt Pharma Ip Trading D.A.C. | Fibrinogen preparations enriched in fibrinogen with an extended alpha chain |
| WO2012140650A2 (en) | 2011-04-12 | 2012-10-18 | Hepacore Ltd. | Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof |
| US20130202656A1 (en) | 2012-02-03 | 2013-08-08 | Dynasil Biomedical Corporation | Systems and kits for the fabrication of tissue patches |
| KR101567053B1 (ko) | 2013-09-30 | 2015-11-09 | 한국원자력의학원 | 방사선 피폭에 의한 간 손상 예측용 바이오마커 및 그 예측방법 |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| US9540548B1 (en) | 2015-08-07 | 2017-01-10 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
| US9833538B2 (en) | 2015-08-07 | 2017-12-05 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
| CA2994959A1 (en) | 2015-08-07 | 2017-02-16 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
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| WO1998055140A1 (en) * | 1997-06-05 | 1998-12-10 | Omrix Biopharmaceuticals S.A. | Fibrinogen concentrate from human plasma |
| WO2000072852A1 (en) * | 1999-06-01 | 2000-12-07 | Bristol-Myers Squibb Company | Prevention of post surgical adhesions using a fibrin monomer sealant |
| EP1142581A2 (en) * | 1990-11-27 | 2001-10-10 | American National Red Cross | Tissue sealant and growth factor containing compositions that promote accelerated wound healing |
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| WO1995029686A1 (en) * | 1994-05-02 | 1995-11-09 | E.R. Squibb & Sons, Inc. | Recombinant fibrin chains, fibrin and fibrin-homologs |
| ATE244584T1 (de) * | 1995-01-16 | 2003-07-15 | Baxter Int | Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen |
| US6037457A (en) * | 1997-01-31 | 2000-03-14 | The University Of North Carolina At Chapel Hill | Method for recombinant fibrinogen production |
| US6946140B1 (en) * | 1999-02-09 | 2005-09-20 | The Research Foundation Of State University Of New York | Methods and compositions for enhancing fibroblast migration |
| AU4351000A (en) * | 1999-04-15 | 2000-11-02 | Research Foundation Of State University Of New York, The | Cellular matrix system and use thereof |
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- 2003-04-07 JP JP2003584115A patent/JP5083928B2/ja not_active Expired - Lifetime
- 2003-04-07 EP EP03723513A patent/EP1495051B1/en not_active Expired - Lifetime
- 2003-04-07 AU AU2003230455A patent/AU2003230455A1/en not_active Abandoned
- 2003-04-07 WO PCT/NL2003/000293 patent/WO2003087160A1/en not_active Ceased
- 2003-04-07 US US10/511,700 patent/US7867519B2/en not_active Expired - Lifetime
- 2003-04-07 CA CA2482893A patent/CA2482893C/en not_active Expired - Lifetime
- 2003-04-07 DK DK03723513T patent/DK1495051T3/da active
- 2003-04-07 DE DE60322687T patent/DE60322687D1/de not_active Expired - Lifetime
- 2003-04-07 AT AT03723513T patent/ATE403679T1/de active
-
2010
- 2010-04-07 JP JP2010088946A patent/JP5395726B2/ja not_active Expired - Lifetime
- 2010-05-06 JP JP2010106630A patent/JP5248547B2/ja not_active Expired - Lifetime
- 2010-11-24 US US12/953,941 patent/US20110071083A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2003230455A1 (en) | 2003-10-27 |
| JP5083928B2 (ja) | 2012-11-28 |
| DE60322687D1 (de) | 2008-09-18 |
| EP1495051A1 (en) | 2005-01-12 |
| JP5248547B2 (ja) | 2013-07-31 |
| US20110071083A1 (en) | 2011-03-24 |
| JP5395726B2 (ja) | 2014-01-22 |
| DK1495051T3 (da) | 2008-11-10 |
| JP2005538045A (ja) | 2005-12-15 |
| EP1495051B1 (en) | 2008-08-06 |
| JP2010246543A (ja) | 2010-11-04 |
| ATE403679T1 (de) | 2008-08-15 |
| US7867519B2 (en) | 2011-01-11 |
| CA2482893A1 (en) | 2003-10-23 |
| JP2010195805A (ja) | 2010-09-09 |
| US20050181972A1 (en) | 2005-08-18 |
| CA2482893C (en) | 2014-08-12 |
| WO2003087160A1 (en) | 2003-10-23 |
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