DE60322687D1 - Veränderung von eigenschaften einer fibrinmatrix in bezug auf das zellwachstum - Google Patents

Veränderung von eigenschaften einer fibrinmatrix in bezug auf das zellwachstum

Info

Publication number
DE60322687D1
DE60322687D1 DE60322687T DE60322687T DE60322687D1 DE 60322687 D1 DE60322687 D1 DE 60322687D1 DE 60322687 T DE60322687 T DE 60322687T DE 60322687 T DE60322687 T DE 60322687T DE 60322687 D1 DE60322687 D1 DE 60322687D1
Authority
DE
Germany
Prior art keywords
fibrinogen
fibrin
lmw
hmw
properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60322687T
Other languages
English (en)
Inventor
Maat Monica Petronella De
Pieter Koolwijk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Original Assignee
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Application granted granted Critical
Publication of DE60322687D1 publication Critical patent/DE60322687D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/046—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60322687T 2002-04-18 2003-04-07 Veränderung von eigenschaften einer fibrinmatrix in bezug auf das zellwachstum Expired - Lifetime DE60322687D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1020426A NL1020426C2 (nl) 2002-04-18 2002-04-18 Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen.
PCT/NL2003/000293 WO2003087160A1 (en) 2002-04-18 2003-04-07 Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells

Publications (1)

Publication Number Publication Date
DE60322687D1 true DE60322687D1 (de) 2008-09-18

Family

ID=29244993

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60322687T Expired - Lifetime DE60322687D1 (de) 2002-04-18 2003-04-07 Veränderung von eigenschaften einer fibrinmatrix in bezug auf das zellwachstum

Country Status (10)

Country Link
US (2) US7867519B2 (de)
EP (1) EP1495051B1 (de)
JP (3) JP5083928B2 (de)
AT (1) ATE403679T1 (de)
AU (1) AU2003230455A1 (de)
CA (1) CA2482893C (de)
DE (1) DE60322687D1 (de)
DK (1) DK1495051T3 (de)
NL (1) NL1020426C2 (de)
WO (1) WO2003087160A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004208038B2 (en) 2003-01-30 2007-09-06 Prochon Biotech Ltd. Freeze-dried fibrin matrices and methods for preparation thereof
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7335508B2 (en) 2004-07-22 2008-02-26 Prochon Biotech Ltd. Porous plasma protein matrices and methods for preparation thereof
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US8921109B2 (en) 2005-09-19 2014-12-30 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
WO2008081463A2 (en) 2007-01-04 2008-07-10 Hepacore Ltd. Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
KR20110040895A (ko) 2008-07-09 2011-04-20 프로피브릭스 비.브이. 재조합 섬유소원
US8846105B2 (en) * 2010-01-08 2014-09-30 Profibrix, B.V. Dry powder fibrin sealant
US20130011382A1 (en) * 2010-01-08 2013-01-10 Profibrix Bv Fibrinogen Preparations Enriched In Fibrinogen With An Extended Alpha Chain
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
US20130202656A1 (en) 2012-02-03 2013-08-08 Dynasil Biomedical Corporation Systems and kits for the fabrication of tissue patches
KR101567053B1 (ko) 2013-09-30 2015-11-09 한국원자력의학원 방사선 피폭에 의한 간 손상 예측용 바이오마커 및 그 예측방법
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CA2994959A1 (en) 2015-08-07 2017-02-16 Xcede Technologies, Inc. Adhesive compositions and related methods
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
US9540548B1 (en) 2015-08-07 2017-01-10 Xcede Technologies, Inc. Adhesive compositions and related methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2097063C (en) * 1990-11-27 2006-08-08 Howard P. Greisler Tissue sealant and growth factor containing compositions that promote accelerated wound healing
WO1995029686A1 (en) * 1994-05-02 1995-11-09 E.R. Squibb & Sons, Inc. Recombinant fibrin chains, fibrin and fibrin-homologs
EP0804257B1 (de) * 1995-01-16 2003-07-09 Baxter International Inc. Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
US6037457A (en) * 1997-01-31 2000-03-14 The University Of North Carolina At Chapel Hill Method for recombinant fibrinogen production
WO1998055140A1 (en) * 1997-06-05 1998-12-10 Omrix Biopharmaceuticals S.A. Fibrinogen concentrate from human plasma
US6946140B1 (en) * 1999-02-09 2005-09-20 The Research Foundation Of State University Of New York Methods and compositions for enhancing fibroblast migration
WO2000062833A1 (en) * 1999-04-15 2000-10-26 The Research Foundation Of State University Of New York Cellular matrix system and use thereof
CA2373704A1 (en) * 1999-06-01 2000-12-07 Bristol-Myers Squibb Company Prevention of post surgical adhesions using a fibrin monomer sealant

Also Published As

Publication number Publication date
CA2482893A1 (en) 2003-10-23
EP1495051B1 (de) 2008-08-06
JP2010195805A (ja) 2010-09-09
JP5248547B2 (ja) 2013-07-31
US7867519B2 (en) 2011-01-11
JP2010246543A (ja) 2010-11-04
EP1495051A1 (de) 2005-01-12
US20050181972A1 (en) 2005-08-18
DK1495051T3 (da) 2008-11-10
JP2005538045A (ja) 2005-12-15
ATE403679T1 (de) 2008-08-15
JP5083928B2 (ja) 2012-11-28
WO2003087160A1 (en) 2003-10-23
US20110071083A1 (en) 2011-03-24
JP5395726B2 (ja) 2014-01-22
NL1020426C2 (nl) 2003-10-21
CA2482893C (en) 2014-08-12
AU2003230455A1 (en) 2003-10-27

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