JP2005536492A - Ｏ−誘導型ノカチアシン誘導体 - Google Patents

Ｏ−誘導型ノカチアシン誘導体 Download PDF

Info

Publication number
JP2005536492A
JP2005536492A JP2004519862A JP2004519862A JP2005536492A JP 2005536492 A JP2005536492 A JP 2005536492A JP 2004519862 A JP2004519862 A JP 2004519862A JP 2004519862 A JP2004519862 A JP 2004519862A JP 2005536492 A JP2005536492 A JP 2005536492A
Authority
JP
Japan
Prior art keywords
group
alkyl
mmol
compound
nocathiacin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2004519862A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005536492A5 (enExample
Inventor
トーマス・ダブリュー・ハディマ
ジェン・シャオファン
ビー・ナラシムル・ナイドゥ
マーガレット・イー・ソレンソン
アリシア・レゲイロ−レン
ティモシー・ピー・コノリー
ジョン・ディ・マティスケラ
オーク・ケイ・キム
ユンフイ・ジャン
デイン・エム・スプリンガー
ジェイソン・グッドリッチ
泰次 植田
ジョアン・ジェイ・ブロンソン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of JP2005536492A publication Critical patent/JP2005536492A/ja
Publication of JP2005536492A5 publication Critical patent/JP2005536492A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP2004519862A 2002-07-03 2003-07-02 Ｏ−誘導型ノカチアシン誘導体 Withdrawn JP2005536492A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/189,710 US7022667B2 (en) 2002-07-03 2002-07-03 O-derivatized nocathiacin derivatives
PCT/US2003/021012 WO2004004646A2 (en) 2002-07-03 2003-07-02 O-derivatized nocathiacin derivatives

Publications (2)

Publication Number Publication Date
JP2005536492A true JP2005536492A (ja) 2005-12-02
JP2005536492A5 JP2005536492A5 (enExample) 2006-04-06

Family

ID=30114034

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004519862A Withdrawn JP2005536492A (ja) 2002-07-03 2003-07-02 Ｏ−誘導型ノカチアシン誘導体

Country Status (9)

Country Link
US (1) US7022667B2 (enExample)
EP (1) EP1531854A4 (enExample)
JP (1) JP2005536492A (enExample)
CN (1) CN1678340A (enExample)
AU (1) AU2003247783A1 (enExample)
BR (1) BR0312550A (enExample)
CA (1) CA2491074A1 (enExample)
MX (1) MXPA05000140A (enExample)
WO (1) WO2004004646A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022149618A1 (ja) * 2021-01-06 2022-07-14 中外製薬株式会社 酸性官能基のアルキル化方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4036440B2 (ja) * 2002-03-29 2008-01-23 東洋合成工業株式会社 新規な感光性化合物及び感光性樹脂並びに感光性組成物
AU2007237861B2 (en) * 2006-04-18 2012-05-10 Council Of Scientific And Industrial Research Novel antibacterial compounds
GB0609617D0 (en) * 2006-05-16 2006-06-21 Astrazeneca Ab Process & intermediate
US20080242597A1 (en) * 2006-10-20 2008-10-02 Kun Liu Antibiotic compounds
US20080132500A1 (en) * 2006-10-20 2008-06-05 Kun Liu Antibiotic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1242052C (zh) 1998-07-16 2006-02-15 布里斯托尔-迈尔斯斯奎布公司 诺卡氏菌的生物纯培养物
WO2000014100A1 (en) 1998-09-04 2000-03-16 Bristol-Myers Squibb Company Nocathiacin antibiotic derivatives prepared by microbial biotransformation
US6287827B1 (en) 1999-05-05 2001-09-11 Bristol-Myers Squibb Company Halo- or hydroxy-substituted nocathiacin antibiotics
US20020055465A1 (en) 2000-08-14 2002-05-09 Wenying Li Nocathiacin antibiotics prepared by biotransformation or chemical methods
US20020065219A1 (en) * 2000-08-15 2002-05-30 Naidu B. Narasimhulu Water soluble thiazolyl peptide derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022149618A1 (ja) * 2021-01-06 2022-07-14 中外製薬株式会社 酸性官能基のアルキル化方法
JPWO2022149618A1 (enExample) * 2021-01-06 2022-07-14
JP7236598B2 (ja) 2021-01-06 2023-03-09 中外製薬株式会社 酸性官能基のアルキル化方法

Also Published As

Publication number Publication date
WO2004004646A3 (en) 2004-09-16
AU2003247783A1 (en) 2004-01-23
US7022667B2 (en) 2006-04-04
US20040018963A1 (en) 2004-01-29
WO2004004646A2 (en) 2004-01-15
BR0312550A (pt) 2005-04-26
CA2491074A1 (en) 2004-01-15
EP1531854A2 (en) 2005-05-25
CN1678340A (zh) 2005-10-05
EP1531854A4 (en) 2006-06-28
MXPA05000140A (es) 2005-04-11

Similar Documents

Publication Publication Date Title
US5344926A (en) Process for producing staurosporine derivatives
EP0786462B1 (en) DC107 derivatives
PL218196B1 (pl) Izomery syn pochodnych kwasów 3-(heteroaryloacetamido) -2-oksoazetydyno-1-sulfonowych jako środki przeciwbakteryjne
CS276964B6 (en) Process for preparing 6'-acylaminopenicillanoyl-oxymethyl esters of penicillanic acid 1,1-dioxide
EP0893446B1 (en) Cephem compounds and drugs containing the compounds
BG100639A (bg) Нова кристална форма на безводна 7-(/1 алфа,5 алфа,6 алфа/-6-амино- 3-азабицикло/3.1.0/хекс-3-ил)-6-флуоро-1-(2,4-дифлуорофенил)-1,4- дихидро-4-оксо-1,8-нафтиридин-3-карбоксилна киселина, метансулфоновокисела сол
US20020065219A1 (en) Water soluble thiazolyl peptide derivatives
EP3774781B1 (en) Novel albicidin derivatives, their use and synthesis
CN108137574B (zh) 羟烷基噻二唑衍生物
JP6654635B2 (ja) 新規なシストバクタミド
WO2017186110A1 (zh) 一类万古霉素衍生物、其制备方法、药物组合物和用途
JP2005536492A (ja) Ｏ−誘導型ノカチアシン誘導体
Kamachi et al. Synthesis and biological activity of a new cephalosporin, BMY-28232 and its prodrug-type esters for oral use
CN104803911A (zh) 一类截短侧耳素化合物、其药物组合物、合成方法与用途
EP0812838A1 (en) Pyridonecarboxylic acid derivative substituted by bicyclic amino group, ester thereof, salt thereof, and bicyclic amine as intermediate therefor
KR870000323B1 (ko) 6-(아미노메틸)페니실란 1,1-디옥사이드 에스테르의 제조방법
KR100274736B1 (ko) 6-엔-(엘-에이엘에이-엘-에이엘에이)-트로바플록사신 전구약물의 폴리모프
EP4249486A1 (en) Albicidin derivatives, their use and synthesis
EP4532474A1 (en) Novel albicidin derivatives, their use and synthesis
CA3056571C (en) N-phosphonoxymethyl prodrugs of hydroxyalkyl thiadiazole derivatives
CS199728B2 (en) Method of producing derivatives of 4"-sulphonyl amino oleandomycin
JP2020511457A5 (enExample)
JPH08504808A (ja) 抗菌活性を有するセフェム化合物
CS276966B6 (en) Process for preparing bis-esters of methane diol with 6'-acylaminopenicillanic acid and penicillanic acid 1,1-dioxide
JPS615089A (ja) 新規アミノグリコシド誘導体

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060214

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060214

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20060614