JP2005535281A5 - - Google Patents
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- Publication number
- JP2005535281A5 JP2005535281A5 JP2003547592A JP2003547592A JP2005535281A5 JP 2005535281 A5 JP2005535281 A5 JP 2005535281A5 JP 2003547592 A JP2003547592 A JP 2003547592A JP 2003547592 A JP2003547592 A JP 2003547592A JP 2005535281 A5 JP2005535281 A5 JP 2005535281A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- nucleic acid
- substituted
- proline
- codon encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001413 amino acids Chemical class 0.000 claims 4
- 108020004705 Codon Proteins 0.000 claims 3
- 235000001014 amino acid Nutrition 0.000 claims 3
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 235000018417 cysteine Nutrition 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34064801P | 2001-11-30 | 2001-11-30 | |
| PCT/EP2002/013059 WO2003046160A2 (en) | 2001-11-30 | 2002-11-21 | Methods of increasing protein expression levels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005535281A JP2005535281A (ja) | 2005-11-24 |
| JP2005535281A5 true JP2005535281A5 (enExample) | 2006-01-12 |
Family
ID=23334343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003547592A Pending JP2005535281A (ja) | 2001-11-30 | 2002-11-21 | タンパク質の発現レベルを増大させるための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7258997B2 (enExample) |
| EP (1) | EP1448772B1 (enExample) |
| JP (1) | JP2005535281A (enExample) |
| AT (1) | ATE367438T1 (enExample) |
| AU (1) | AU2002338947B2 (enExample) |
| CA (1) | CA2466298A1 (enExample) |
| DE (1) | DE60221273D1 (enExample) |
| DK (1) | DK1448772T3 (enExample) |
| ES (1) | ES2290337T3 (enExample) |
| IL (1) | IL162133A0 (enExample) |
| PT (1) | PT1448772E (enExample) |
| WO (1) | WO2003046160A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1448772B1 (en) * | 2001-11-30 | 2007-07-18 | Applied Research Systems ARS Holding N.V. | Methods of increasing expression levels of human tnf receptor |
| JP2008504009A (ja) * | 2003-12-23 | 2008-02-14 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 腫瘍壊死因子結合蛋白質を生産する方法 |
| US8722348B2 (en) | 2008-05-28 | 2014-05-13 | Wayne State University | Method and composition for a protein transduction technology and its applications |
| CN103826459B (zh) | 2011-05-02 | 2017-05-10 | 韦恩州立大学 | 蛋白质诱导的多能细胞技术及其用途 |
| PT3060237T (pt) | 2013-10-25 | 2021-11-09 | Univ Wayne State | Proteína de reprogramação modificada para utilização no tratamento de um cancro |
| US20240218357A1 (en) * | 2019-06-21 | 2024-07-04 | Kernal Biologics, Inc. | Engineered oncoselective protein expression |
| JP2023522534A (ja) * | 2020-02-03 | 2023-05-31 | プレマス バイオテック プライベート リミテッド | 発現が困難なタンパク質を発現させるための、組換え発現プラットフォーム、構築物、および方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2238070T3 (es) * | 1989-04-21 | 2005-08-16 | Amgen Inc. | Receptor del tnf, proteina ligante del tnf y adn codante para estos. |
| EP0614353A1 (en) * | 1991-11-25 | 1994-09-14 | Richardson-Vicks, Inc. | Compositions for regulating skin wrinkles and/or skin atrophy |
| IL107268A0 (en) * | 1993-10-12 | 1994-01-25 | Yeda Res & Dev | Molecules influencing the shedding of the tnf receptor, their preparation and their use |
| US7074901B2 (en) * | 2001-05-25 | 2006-07-11 | Serono Genetics Institute S.A. | Isolated human vCOL16A1 polypeptide and fragments thereof |
| EP1448772B1 (en) * | 2001-11-30 | 2007-07-18 | Applied Research Systems ARS Holding N.V. | Methods of increasing expression levels of human tnf receptor |
-
2002
- 2002-11-21 EP EP02777356A patent/EP1448772B1/en not_active Expired - Lifetime
- 2002-11-21 AU AU2002338947A patent/AU2002338947B2/en not_active Ceased
- 2002-11-21 JP JP2003547592A patent/JP2005535281A/ja active Pending
- 2002-11-21 CA CA002466298A patent/CA2466298A1/en not_active Abandoned
- 2002-11-21 PT PT02777356T patent/PT1448772E/pt unknown
- 2002-11-21 DK DK02777356T patent/DK1448772T3/da active
- 2002-11-21 US US10/496,218 patent/US7258997B2/en not_active Expired - Fee Related
- 2002-11-21 AT AT02777356T patent/ATE367438T1/de not_active IP Right Cessation
- 2002-11-21 WO PCT/EP2002/013059 patent/WO2003046160A2/en not_active Ceased
- 2002-11-21 DE DE60221273T patent/DE60221273D1/de not_active Expired - Lifetime
- 2002-11-21 ES ES02777356T patent/ES2290337T3/es not_active Expired - Lifetime
- 2002-11-21 IL IL16213302A patent/IL162133A0/xx unknown
-
2007
- 2007-07-16 US US11/778,593 patent/US20080014635A1/en not_active Abandoned
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