DK1448772T3 - Fremgangsmåder til forögelse af ekspressionsniveauer af human TNF-receptor - Google Patents

Fremgangsmåder til forögelse af ekspressionsniveauer af human TNF-receptor

Info

Publication number
DK1448772T3
DK1448772T3 DK02777356T DK02777356T DK1448772T3 DK 1448772 T3 DK1448772 T3 DK 1448772T3 DK 02777356 T DK02777356 T DK 02777356T DK 02777356 T DK02777356 T DK 02777356T DK 1448772 T3 DK1448772 T3 DK 1448772T3
Authority
DK
Denmark
Prior art keywords
methods
amino acid
expression levels
proline
tnf receptor
Prior art date
Application number
DK02777356T
Other languages
English (en)
Inventor
William Brondyk
Xuliang Jiang
Rene Lynn Schweickhardt
Original Assignee
Serono Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Lab filed Critical Serono Lab
Application granted granted Critical
Publication of DK1448772T3 publication Critical patent/DK1448772T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/144—Tumor necrosis factor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK02777356T 2001-11-30 2002-11-21 Fremgangsmåder til forögelse af ekspressionsniveauer af human TNF-receptor DK1448772T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34064801P 2001-11-30 2001-11-30
PCT/EP2002/013059 WO2003046160A2 (en) 2001-11-30 2002-11-21 Methods of increasing protein expression levels

Publications (1)

Publication Number Publication Date
DK1448772T3 true DK1448772T3 (da) 2007-11-19

Family

ID=23334343

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02777356T DK1448772T3 (da) 2001-11-30 2002-11-21 Fremgangsmåder til forögelse af ekspressionsniveauer af human TNF-receptor

Country Status (12)

Country Link
US (2) US7258997B2 (da)
EP (1) EP1448772B1 (da)
JP (1) JP2005535281A (da)
AT (1) ATE367438T1 (da)
AU (1) AU2002338947B2 (da)
CA (1) CA2466298A1 (da)
DE (1) DE60221273D1 (da)
DK (1) DK1448772T3 (da)
ES (1) ES2290337T3 (da)
IL (1) IL162133A0 (da)
PT (1) PT1448772E (da)
WO (1) WO2003046160A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003046160A2 (en) * 2001-11-30 2003-06-05 Applied Research Systems Ars Holding N.V. Methods of increasing protein expression levels
EP1697414A2 (en) * 2003-12-23 2006-09-06 Applied Research Systems ARS Holding N.V. Process for the production of tumor necrosis factor-binding proteins
US8722348B2 (en) 2008-05-28 2014-05-13 Wayne State University Method and composition for a protein transduction technology and its applications
EP2705143B1 (en) 2011-05-02 2021-02-17 Wayne State University A protein-induced pluripotent cell technology uses thereof
PT3060237T (pt) 2013-10-25 2021-11-09 Univ Wayne State Proteína de reprogramação modificada para utilização no tratamento de um cancro
EP3987028A4 (en) * 2019-06-21 2023-07-19 Kernal Biologics, Inc. MODIFIED ONCOSELECTIVE PROTEIN EXPRESSION

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0393438B1 (de) * 1989-04-21 2005-02-16 Amgen Inc. TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs
JPH07501540A (ja) * 1991-11-25 1995-02-16 リチャードソン、ビックス、インコーポレーテッド 皮膚シワ及び／又は皮膚萎縮を調節するための組成物
IL107268A0 (en) * 1993-10-12 1994-01-25 Yeda Res & Dev Molecules influencing the shedding of the tnf receptor, their preparation and their use
EP1390497A2 (en) * 2001-05-25 2004-02-25 Genset Human cdnas and proteins and uses thereof
WO2003046160A2 (en) * 2001-11-30 2003-06-05 Applied Research Systems Ars Holding N.V. Methods of increasing protein expression levels

Also Published As

Publication number Publication date
CA2466298A1 (en) 2003-06-05
EP1448772A2 (en) 2004-08-25
ATE367438T1 (de) 2007-08-15
ES2290337T3 (es) 2008-02-16
IL162133A0 (en) 2005-11-20
EP1448772B1 (en) 2007-07-18
PT1448772E (pt) 2007-10-02
AU2002338947A1 (en) 2003-06-10
WO2003046160A2 (en) 2003-06-05
AU2002338947B2 (en) 2007-09-13
US20050074840A1 (en) 2005-04-07
DE60221273D1 (de) 2007-08-30
US20080014635A1 (en) 2008-01-17
JP2005535281A (ja) 2005-11-24
US7258997B2 (en) 2007-08-21
WO2003046160A3 (en) 2003-07-31

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