JP2007510403A5 - - Google Patents
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- Publication number
- JP2007510403A5 JP2007510403A5 JP2006534768A JP2006534768A JP2007510403A5 JP 2007510403 A5 JP2007510403 A5 JP 2007510403A5 JP 2006534768 A JP2006534768 A JP 2006534768A JP 2006534768 A JP2006534768 A JP 2006534768A JP 2007510403 A5 JP2007510403 A5 JP 2007510403A5
- Authority
- JP
- Japan
- Prior art keywords
- isoleucine
- seq
- use according
- polypeptide further
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 125000000741 isoleucyl group Chemical group [H]N([H])C(C(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)O* 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03078308 | 2003-10-16 | ||
| PCT/EP2004/052572 WO2005037305A1 (en) | 2003-10-16 | 2004-10-18 | Therapeutic uses of chemokine variants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007510403A JP2007510403A (ja) | 2007-04-26 |
| JP2007510403A5 true JP2007510403A5 (enExample) | 2007-12-06 |
Family
ID=34442986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534768A Pending JP2007510403A (ja) | 2003-10-16 | 2004-10-18 | ケモカイン変異体の治療への使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7740833B2 (enExample) |
| EP (1) | EP1673103A1 (enExample) |
| JP (1) | JP2007510403A (enExample) |
| KR (1) | KR20070008510A (enExample) |
| CN (1) | CN1867352A (enExample) |
| AR (1) | AR046594A1 (enExample) |
| AU (1) | AU2004281552B2 (enExample) |
| BR (1) | BRPI0415290A (enExample) |
| CA (1) | CA2536082A1 (enExample) |
| EA (1) | EA009414B1 (enExample) |
| IL (1) | IL175020A0 (enExample) |
| MX (1) | MXPA06003695A (enExample) |
| NO (1) | NO20062109L (enExample) |
| UA (1) | UA91820C2 (enExample) |
| WO (1) | WO2005037305A1 (enExample) |
| ZA (1) | ZA200601900B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101443357A (zh) | 2005-08-12 | 2009-05-27 | 先灵公司 | Mcp1融合物 |
| WO2007113285A2 (en) * | 2006-03-31 | 2007-10-11 | Biotherapix Molecular Medicines S.L.U. | Mono- and bifunctional molecules with ability to bind to g protein-coupled receptors |
| US20100166733A1 (en) * | 2006-06-21 | 2010-07-01 | Zurit Levin | Mcp-1 splice variants and methods of using same |
| ES2434039T3 (es) * | 2006-07-24 | 2013-12-13 | Yeda Research And Development Co. Ltd. | Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación |
| US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
| WO2010086426A1 (en) * | 2009-01-30 | 2010-08-05 | Protaffin Biotechnologie Ag | Glycosaminoglycan-antagonising mcp-i mutants and methods of using same |
| US8524217B2 (en) | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
| US9249204B2 (en) | 2011-06-01 | 2016-02-02 | Jyant Technologies, Inc. | Chemokine-immunoglobulin fusion polypeptides, compositions, method of making and use thereof |
| US8541564B2 (en) * | 2011-06-01 | 2013-09-24 | Morehouse School Of Medicine | Chemokine-immunoglobulin fusion polypeptides, compositions, method of making and use thereof |
| US8796422B2 (en) * | 2011-06-01 | 2014-08-05 | Morehouse School Of Medicine | Chemokine-immunoglobulin fusion polypeptides, compositions, method of making and use thereof |
| US9726666B2 (en) | 2011-06-13 | 2017-08-08 | Tla Targeted Immunotherapies Ab | Diagnosing and treating inflammatory diseases |
| DK2718311T3 (en) * | 2011-06-13 | 2018-04-16 | Tla Targeted Immunotherapies Ab | TREATMENT OF MULTIPLE SCLEROSIS |
| EP3613435A1 (en) | 2015-01-28 | 2020-02-26 | Universite De Bordeaux | Chemokine receptor cxcr4 inhibitors for treating and/or preventing chronic obstructive pulmonary disease |
| EP3253797A4 (en) * | 2015-02-03 | 2018-10-03 | Jyant Technologies, Inc. | Chemokine-immunoglobulin fusion polypeptides, compositions, method of making and use thereof |
| EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018112264A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| KR102066149B1 (ko) * | 2018-08-17 | 2020-01-14 | 고려대학교 산학협력단 | Ccl2를 유효성분으로 포함하는 임신촉진용 조성물 |
| AU2019383976B2 (en) | 2018-11-19 | 2025-07-03 | Bt Bidco, Inc. | Methods and devices for treating a disease with biotherapeutics |
| US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ273052A (en) * | 1993-09-14 | 1997-12-19 | Imperial College | Chemoattractant protein capable of attracting eosinophils and inducing accumulation thereof |
| US5459128A (en) * | 1993-11-12 | 1995-10-17 | Dana-Farber Cancer Institute | Human monocyte chemoattractant protein-1 (MCP-1) derivatives |
| US5739103A (en) * | 1993-11-12 | 1998-04-14 | Dana-Farber Cancer Institute | Chemokine N-terminal deletion mutations |
| WO1998031794A1 (fr) * | 1997-01-17 | 1998-07-23 | Toa Gosei Co., Ltd. | Polypeptide liant le facteur vegf |
| US6100387A (en) * | 1997-02-28 | 2000-08-08 | Genetics Institute, Inc. | Chimeric polypeptides containing chemokine domains |
| JP4793971B2 (ja) * | 1999-08-09 | 2011-10-12 | メルク パテント ゲーエムベーハー | 複合サイトカイン−抗体複合体 |
| US7332474B2 (en) * | 2001-10-11 | 2008-02-19 | Amgen Inc. | Peptides and related compounds having thrombopoietic activity |
| CA2463003A1 (en) * | 2001-10-19 | 2003-04-24 | Zymogenetics, Inc. | Dimerized growth factor and materials and methods for producing it |
| EP1497423A4 (en) | 2002-03-26 | 2006-05-24 | Centocor Inc | MUTANT MCP-1 PROTEINS, ANTIBODIES, COMPOSITIONS, PROCESSES AND USES |
| WO2003084993A1 (en) * | 2002-04-10 | 2003-10-16 | Applied Research Systems Ars Holding N.V. | Novel antagonists of mcp proteins |
| WO2007113285A2 (en) * | 2006-03-31 | 2007-10-11 | Biotherapix Molecular Medicines S.L.U. | Mono- and bifunctional molecules with ability to bind to g protein-coupled receptors |
-
2004
- 2004-10-15 AR ARP040103735A patent/AR046594A1/es not_active Application Discontinuation
- 2004-10-18 BR BRPI0415290-5A patent/BRPI0415290A/pt not_active IP Right Cessation
- 2004-10-18 JP JP2006534768A patent/JP2007510403A/ja active Pending
- 2004-10-18 EP EP04791250A patent/EP1673103A1/en not_active Withdrawn
- 2004-10-18 CN CNA2004800303865A patent/CN1867352A/zh active Pending
- 2004-10-18 CA CA002536082A patent/CA2536082A1/en not_active Abandoned
- 2004-10-18 ZA ZA200601900A patent/ZA200601900B/en unknown
- 2004-10-18 AU AU2004281552A patent/AU2004281552B2/en not_active Ceased
- 2004-10-18 KR KR1020067005198A patent/KR20070008510A/ko not_active Ceased
- 2004-10-18 UA UAA200604131A patent/UA91820C2/ru unknown
- 2004-10-18 MX MXPA06003695A patent/MXPA06003695A/es active IP Right Grant
- 2004-10-18 EA EA200600782A patent/EA009414B1/ru not_active IP Right Cessation
- 2004-10-18 WO PCT/EP2004/052572 patent/WO2005037305A1/en not_active Ceased
- 2004-10-18 US US10/573,625 patent/US7740833B2/en not_active Expired - Fee Related
-
2006
- 2006-04-20 IL IL175020A patent/IL175020A0/en unknown
- 2006-05-11 NO NO20062109A patent/NO20062109L/no not_active Application Discontinuation
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