IL162133A0 - Method of increasing protein expression, proteins and polynucleotides - Google Patents
Method of increasing protein expression, proteins and polynucleotidesInfo
- Publication number
- IL162133A0 IL162133A0 IL16213302A IL16213302A IL162133A0 IL 162133 A0 IL162133 A0 IL 162133A0 IL 16213302 A IL16213302 A IL 16213302A IL 16213302 A IL16213302 A IL 16213302A IL 162133 A0 IL162133 A0 IL 162133A0
- Authority
- IL
- Israel
- Prior art keywords
- amino acid
- polynucleotides
- proline
- protein expression
- proteins
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 7
- 235000001014 amino acid Nutrition 0.000 abstract 6
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 4
- 108020004705 Codon Proteins 0.000 abstract 3
- 238000006467 substitution reaction Methods 0.000 abstract 3
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
- Y10S930/144—Tumor necrosis factor
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34064801P | 2001-11-30 | 2001-11-30 | |
| PCT/EP2002/013059 WO2003046160A2 (en) | 2001-11-30 | 2002-11-21 | Methods of increasing protein expression levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL162133A0 true IL162133A0 (en) | 2005-11-20 |
Family
ID=23334343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16213302A IL162133A0 (en) | 2001-11-30 | 2002-11-21 | Method of increasing protein expression, proteins and polynucleotides |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7258997B2 (enExample) |
| EP (1) | EP1448772B1 (enExample) |
| JP (1) | JP2005535281A (enExample) |
| AT (1) | ATE367438T1 (enExample) |
| AU (1) | AU2002338947B2 (enExample) |
| CA (1) | CA2466298A1 (enExample) |
| DE (1) | DE60221273D1 (enExample) |
| DK (1) | DK1448772T3 (enExample) |
| ES (1) | ES2290337T3 (enExample) |
| IL (1) | IL162133A0 (enExample) |
| PT (1) | PT1448772E (enExample) |
| WO (1) | WO2003046160A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1448772B1 (en) * | 2001-11-30 | 2007-07-18 | Applied Research Systems ARS Holding N.V. | Methods of increasing expression levels of human tnf receptor |
| AU2004309114A1 (en) * | 2003-12-23 | 2005-07-14 | Laboratoires Serono Sa | Process for the production of tumor necrosis factor-binding proteins |
| US8722348B2 (en) | 2008-05-28 | 2014-05-13 | Wayne State University | Method and composition for a protein transduction technology and its applications |
| EP2705143B1 (en) | 2011-05-02 | 2021-02-17 | Wayne State University | A protein-induced pluripotent cell technology uses thereof |
| JP6415582B2 (ja) | 2013-10-25 | 2018-10-31 | ウェイン ステート ユニバーシティー | タンパク質誘導生体内細胞リプログラミングによる細胞転換に関する方法、システム、及び組成物 |
| JP2022537052A (ja) * | 2019-06-21 | 2022-08-23 | カーナル バイオロジクス， インコーポレイテッド | 操作された腫瘍選択的タンパク質発現 |
| EP4100038A4 (en) * | 2020-02-03 | 2024-02-28 | Premas Biotech Private Limited | RECOMBINANT EXPRESSION PLATFORM, CONSTRUCTS AND METHODS FOR EXPRESSING HARD-TO-EXPRESS PROTEINS (DTE-PS) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0393438T3 (da) * | 1989-04-21 | 2005-05-30 | Amgen Inc | TNF-receptor, TNF-bindende proteiner og DNAér, der koder herfor |
| AU3073692A (en) * | 1991-11-25 | 1993-06-28 | Richardson-Vicks Inc. | Compositions for regulating skin wrinkles and/or skin atrophy |
| IL107268A0 (en) * | 1993-10-12 | 1994-01-25 | Yeda Res & Dev | Molecules influencing the shedding of the tnf receptor, their preparation and their use |
| AU2001286171B2 (en) * | 2001-05-25 | 2008-01-10 | Serono Genetics Institute S.A. | Human CDNAs and proteins and uses thereof |
| EP1448772B1 (en) * | 2001-11-30 | 2007-07-18 | Applied Research Systems ARS Holding N.V. | Methods of increasing expression levels of human tnf receptor |
-
2002
- 2002-11-21 EP EP02777356A patent/EP1448772B1/en not_active Expired - Lifetime
- 2002-11-21 JP JP2003547592A patent/JP2005535281A/ja active Pending
- 2002-11-21 PT PT02777356T patent/PT1448772E/pt unknown
- 2002-11-21 AT AT02777356T patent/ATE367438T1/de not_active IP Right Cessation
- 2002-11-21 DE DE60221273T patent/DE60221273D1/de not_active Expired - Lifetime
- 2002-11-21 WO PCT/EP2002/013059 patent/WO2003046160A2/en not_active Ceased
- 2002-11-21 IL IL16213302A patent/IL162133A0/xx unknown
- 2002-11-21 CA CA002466298A patent/CA2466298A1/en not_active Abandoned
- 2002-11-21 AU AU2002338947A patent/AU2002338947B2/en not_active Ceased
- 2002-11-21 ES ES02777356T patent/ES2290337T3/es not_active Expired - Lifetime
- 2002-11-21 US US10/496,218 patent/US7258997B2/en not_active Expired - Fee Related
- 2002-11-21 DK DK02777356T patent/DK1448772T3/da active
-
2007
- 2007-07-16 US US11/778,593 patent/US20080014635A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7258997B2 (en) | 2007-08-21 |
| ES2290337T3 (es) | 2008-02-16 |
| EP1448772A2 (en) | 2004-08-25 |
| CA2466298A1 (en) | 2003-06-05 |
| PT1448772E (pt) | 2007-10-02 |
| WO2003046160A2 (en) | 2003-06-05 |
| ATE367438T1 (de) | 2007-08-15 |
| JP2005535281A (ja) | 2005-11-24 |
| US20080014635A1 (en) | 2008-01-17 |
| AU2002338947B2 (en) | 2007-09-13 |
| AU2002338947A1 (en) | 2003-06-10 |
| EP1448772B1 (en) | 2007-07-18 |
| WO2003046160A3 (en) | 2003-07-31 |
| US20050074840A1 (en) | 2005-04-07 |
| DK1448772T3 (da) | 2007-11-19 |
| DE60221273D1 (de) | 2007-08-30 |
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