JP2005534330A - アルブミン融合繊毛様神経栄養因子 - Google Patents

アルブミン融合繊毛様神経栄養因子 Download PDF

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Publication number
JP2005534330A
JP2005534330A JP2004526896A JP2004526896A JP2005534330A JP 2005534330 A JP2005534330 A JP 2005534330A JP 2004526896 A JP2004526896 A JP 2004526896A JP 2004526896 A JP2004526896 A JP 2004526896A JP 2005534330 A JP2005534330 A JP 2005534330A
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Prior art keywords
protein
albumin
biologically active
active peptide
cntf
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Pending
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JP2004526896A
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English (en)
Japanese (ja)
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JP2005534330A5 (ko
Inventor
マティアス、ユルス
トマス、バイメル
ハンス‐ペーター、ハウザー
ダレル、スリープ
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Albumedix Ltd
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Delta Biotechnology Ltd
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Publication date
Application filed by Delta Biotechnology Ltd filed Critical Delta Biotechnology Ltd
Publication of JP2005534330A publication Critical patent/JP2005534330A/ja
Publication of JP2005534330A5 publication Critical patent/JP2005534330A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2004526896A 2002-08-07 2003-08-06 アルブミン融合繊毛様神経栄養因子 Pending JP2005534330A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40183302P 2002-08-07 2002-08-07
PCT/EP2003/008710 WO2004015113A2 (en) 2002-08-07 2003-08-06 Albumin-fused ciliary neurotrophic factor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010089560A Division JP2010213707A (ja) 2002-08-07 2010-04-08 アルブミン融合繊毛様神経栄養因子

Publications (2)

Publication Number Publication Date
JP2005534330A true JP2005534330A (ja) 2005-11-17
JP2005534330A5 JP2005534330A5 (ko) 2006-08-24

Family

ID=31715745

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004526896A Pending JP2005534330A (ja) 2002-08-07 2003-08-06 アルブミン融合繊毛様神経栄養因子
JP2010089560A Withdrawn JP2010213707A (ja) 2002-08-07 2010-04-08 アルブミン融合繊毛様神経栄養因子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010089560A Withdrawn JP2010213707A (ja) 2002-08-07 2010-04-08 アルブミン融合繊毛様神経栄養因子

Country Status (6)

Country Link
EP (1) EP1529108A2 (ko)
JP (2) JP2005534330A (ko)
KR (1) KR20050065519A (ko)
AU (1) AU2003271043A1 (ko)
CA (1) CA2496002A1 (ko)
WO (1) WO2004015113A2 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
GB0329681D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
JP5631533B2 (ja) 2004-12-23 2014-11-26 ノボザイムス バイオファーマ デーコー アクティーゼルスカブ 遺伝子発現技術
CN102462662A (zh) * 2010-08-16 2012-05-23 重庆富进生物医药有限公司 脂质体包裹重组人睫状神经营养因子

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000502901A (ja) * 1995-12-30 2000-03-14 デルタ、バイオテクノロジー、リミテッド 成長ホルモンおよび血清アルブミンに対する組換え融合タンパク質

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2719593B1 (fr) * 1994-05-06 1996-05-31 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur préparation et composition pharmaceutique les contenant.
CA2405701A1 (en) * 2000-04-12 2001-10-25 Human Genome Sciences, Inc. Albumin fusion proteins
WO2002002627A2 (en) * 2000-06-30 2002-01-10 Zymogenetics, Inc. Interferon-like protein zcyto21

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000502901A (ja) * 1995-12-30 2000-03-14 デルタ、バイオテクノロジー、リミテッド 成長ホルモンおよび血清アルブミンに対する組換え融合タンパク質

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
EUR. J. BIOCHEM., vol. 231, JPN6009021147, 1995, pages 563 - 569, ISSN: 0001313675 *
INT. J. OBES., vol. 24, no. 1, JPN6009021142, 2000, pages 102 - 328, ISSN: 0001313677 *
INT. J. OBES., vol. 25, no. 2, JPN6009021149, 2001, pages 111 - 291, ISSN: 0001313674 *
PROC. NATL. ACAD. SCI. USA., vol. 89, JPN6009021145, 1992, pages 1904 - 1908, ISSN: 0001313676 *
PROC. NATL. ACAD. SCI. USA., vol. 98, no. 8, JPN6009021143, 2001, pages 4652 - 4657, ISSN: 0001313678 *

Also Published As

Publication number Publication date
AU2003271043A1 (en) 2004-02-25
WO2004015113A2 (en) 2004-02-19
KR20050065519A (ko) 2005-06-29
CA2496002A1 (en) 2004-02-19
WO2004015113A3 (en) 2004-05-06
JP2010213707A (ja) 2010-09-30
EP1529108A2 (en) 2005-05-11

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