JP2005534308A5 - - Google Patents

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Publication number
JP2005534308A5
JP2005534308A5 JP2004524915A JP2004524915A JP2005534308A5 JP 2005534308 A5 JP2005534308 A5 JP 2005534308A5 JP 2004524915 A JP2004524915 A JP 2004524915A JP 2004524915 A JP2004524915 A JP 2004524915A JP 2005534308 A5 JP2005534308 A5 JP 2005534308A5
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JP
Japan
Prior art keywords
adamts4 protein
modified
protein
modified adamts4
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004524915A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005534308A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/023484 external-priority patent/WO2004011637A2/en
Publication of JP2005534308A publication Critical patent/JP2005534308A/ja
Publication of JP2005534308A5 publication Critical patent/JP2005534308A5/ja
Pending legal-status Critical Current

Links

JP2004524915A 2002-07-29 2003-07-29 修飾ａｄａｍｔｓ４分子およびその使用法 Pending JP2005534308A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39872102P 2002-07-29 2002-07-29
PCT/US2003/023484 WO2004011637A2 (en) 2002-07-29 2003-07-29 Modified adamts4 molecules and method of use thereof

Publications (2)

Publication Number Publication Date
JP2005534308A JP2005534308A (ja) 2005-11-17
JP2005534308A5 true JP2005534308A5 (enExample) 2006-09-14

Family

ID=31188463

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004524915A Pending JP2005534308A (ja) 2002-07-29 2003-07-29 修飾ａｄａｍｔｓ４分子およびその使用法

Country Status (10)

Country Link
US (2) US7118902B2 (enExample)
EP (1) EP1525307A2 (enExample)
JP (1) JP2005534308A (enExample)
CN (1) CN1681920A (enExample)
AU (1) AU2003261269A1 (enExample)
BR (1) BR0313083A (enExample)
CA (1) CA2492444A1 (enExample)
IL (1) IL166535A0 (enExample)
MX (1) MXPA05000959A (enExample)
WO (1) WO2004011637A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4252892B2 (ja) 2001-06-01 2009-04-08 三菱製紙株式会社 全熱交換素子用紙
JP2005516614A (ja) 2002-02-05 2005-06-09 ワイス 切断アグレカナーゼ分子
CN1681920A (zh) * 2002-07-29 2005-10-12 惠氏公司 修饰的admts4分子及其使用方法
US7696307B2 (en) * 2004-04-12 2010-04-13 The Trustees Of The University Of Pennsylvania Function and regulation of ADAMTS-1
JP2007535920A (ja) * 2004-04-16 2007-12-13 ワイス トランケート型ａｄａｍｔｓ分子
WO2007025248A2 (en) * 2005-08-25 2007-03-01 Wyeth Aggrecanase structure
US7625731B2 (en) 2005-08-25 2009-12-01 Wyeth Aggrecanase structure
GB0601976D0 (en) * 2006-02-01 2006-03-15 Merck Sharp & Dohme Proteins
US20100062431A1 (en) * 2006-05-18 2010-03-11 Sanofi-Aventis Use of adamts4 gene and protein polymorphisms
US8263072B2 (en) * 2007-06-22 2012-09-11 Genera Istrazivanja, d.o.o. ADAMTS4 as a blood biomarker and therapeutic target for chronic renal failure
JP5341756B2 (ja) * 2007-06-29 2013-11-13 国立大学法人名古屋大学 神経障害に基づく機能不全の改善剤およびＲｈｏキナーゼ活性化抑制剤
EP2420250A1 (en) 2010-08-13 2012-02-22 Universitätsklinikum Münster Anti-Syndecan-4 antibodies
CA2927525C (en) 2013-10-15 2023-01-31 Genefrontier Corporation Human antibody against aggrecanase-type adamts species for therapeutics of aggrecanase-related diseases

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3451575A (en) * 1967-09-15 1969-06-24 Geza Petro Jr Conveyor bucket with hydraulically-operated grille-like lid
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4522811A (en) * 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4588684A (en) 1983-04-26 1986-05-13 Chiron Corporation a-Factor and its processing signals
ES8701226A1 (es) 1984-07-06 1986-11-16 Sandoz Ag Procedimiento de obtencion de una proteina de factor estimu-lante de colonias (csf) en primates
EP0177343B1 (en) 1984-10-05 1992-07-22 Genentech, Inc. Dna, cell cultures and methods for the secretion of heterologous proteins and periplasmic protein recovery
US6069229A (en) * 1997-03-07 2000-05-30 Schering Corporation Mammalian proteinases; oxidoreductases; related reagents
AU8513198A (en) * 1997-07-25 1999-02-16 Du Pont Pharmaceuticals Company Aggrecan degrading metallo proteases
US6842704B2 (en) * 1998-02-04 2005-01-11 Immunex Corporation Crystalline TNF-α-converting enzyme and uses thereof
WO2000053774A2 (en) * 1999-03-08 2000-09-14 Neurocrine Biosciences, Inc. Metalloproteinases and methods of use therefor
US6391610B1 (en) * 1999-08-06 2002-05-21 The Cleveland Clinic Foundation Nucleic acids encoding zinc metalloproteases
EP1136547A3 (en) * 2000-03-22 2002-09-25 Pfizer Products Inc. Adamts polypeptides, nucleic acids encoding them, and uses thereof
US6458552B1 (en) * 2000-06-06 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. Metalloprotease peptide substrates and methods
US20020151702A1 (en) * 2000-10-18 2002-10-17 Genetics Institute, Inc. Aggrecanase molecules
SE0102298D0 (sv) * 2001-06-27 2001-06-27 Astrazeneca Ab Crystal structure of enzyme and uses thereof
US20030148306A1 (en) * 2001-07-05 2003-08-07 Agostino Michael J. Aggrecanase molecules
WO2003016492A2 (en) * 2001-08-16 2003-02-27 The Regents Of The University Of Michigan Adamts13 genes and proteins and variants, and uses thereof
US20030105313A1 (en) * 2001-10-16 2003-06-05 American Home Products Corporation Aggrecanase molecules
JP2005515779A (ja) * 2002-01-31 2005-06-02 ワイス アグレカナーゼ分子
JP2005516614A (ja) * 2002-02-05 2005-06-09 ワイス 切断アグレカナーゼ分子
CN1681920A (zh) * 2002-07-29 2005-10-12 惠氏公司 修饰的admts4分子及其使用方法

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