MXPA05000959A - Moleculas adamts4 modificadas y metodo de uso de las mismas. - Google Patents
Moleculas adamts4 modificadas y metodo de uso de las mismas.Info
- Publication number
- MXPA05000959A MXPA05000959A MXPA05000959A MXPA05000959A MXPA05000959A MX PA05000959 A MXPA05000959 A MX PA05000959A MX PA05000959 A MXPA05000959 A MX PA05000959A MX PA05000959 A MXPA05000959 A MX PA05000959A MX PA05000959 A MXPA05000959 A MX PA05000959A
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- adamts4
- modified
- aggrecanase
- mts4
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39872102P | 2002-07-29 | 2002-07-29 | |
| PCT/US2003/023484 WO2004011637A2 (en) | 2002-07-29 | 2003-07-29 | Modified adamts4 molecules and method of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05000959A true MXPA05000959A (es) | 2005-05-16 |
Family
ID=31188463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05000959A MXPA05000959A (es) | 2002-07-29 | 2003-07-29 | Moleculas adamts4 modificadas y metodo de uso de las mismas. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7118902B2 (enExample) |
| EP (1) | EP1525307A2 (enExample) |
| JP (1) | JP2005534308A (enExample) |
| CN (1) | CN1681920A (enExample) |
| AU (1) | AU2003261269A1 (enExample) |
| BR (1) | BR0313083A (enExample) |
| CA (1) | CA2492444A1 (enExample) |
| IL (1) | IL166535A0 (enExample) |
| MX (1) | MXPA05000959A (enExample) |
| WO (1) | WO2004011637A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR100520722B1 (ko) | 2001-06-01 | 2005-10-11 | 미쓰비시 세이시 가부시키가이샤 | 전(全)열교환 소자용지 |
| WO2003066822A2 (en) | 2002-02-05 | 2003-08-14 | Wyeth | Truncated aggrecanase molecules |
| AU2003261269A1 (en) * | 2002-07-29 | 2004-02-16 | Wyeth | Modified adamts4 molecules and method of use thereof |
| US7696307B2 (en) * | 2004-04-12 | 2010-04-13 | The Trustees Of The University Of Pennsylvania | Function and regulation of ADAMTS-1 |
| JP2007535920A (ja) * | 2004-04-16 | 2007-12-13 | ワイス | トランケート型adamts分子 |
| CN101300345A (zh) | 2005-08-25 | 2008-11-05 | 惠氏公司 | 聚集蛋白聚糖酶结构 |
| WO2007025248A2 (en) * | 2005-08-25 | 2007-03-01 | Wyeth | Aggrecanase structure |
| GB0601976D0 (en) * | 2006-02-01 | 2006-03-15 | Merck Sharp & Dohme | Proteins |
| EP2027284A2 (en) * | 2006-05-18 | 2009-02-25 | Sanofi-Aventis | Use of adamts4 gene and protein polymorphisms |
| EP2455755A3 (en) * | 2007-06-22 | 2012-08-15 | GENERA ISTRAZIVANJA d.o.o. | Proteaoglycan-4 as marker for chronic renal failure |
| WO2009005033A1 (ja) * | 2007-06-29 | 2009-01-08 | National University Corporation Nagoya University | 神経障害に基づく機能不全の改善剤およびRhoキナーゼ活性化抑制剤 |
| EP2420250A1 (en) | 2010-08-13 | 2012-02-22 | Universitätsklinikum Münster | Anti-Syndecan-4 antibodies |
| WO2015056808A1 (en) | 2013-10-15 | 2015-04-23 | Genefrontier Corporation | Human antibody against aggrecanase-type adamts species for therapeutics of aggrecanase-related diseases |
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| US3451575A (en) * | 1967-09-15 | 1969-06-24 | Geza Petro Jr | Conveyor bucket with hydraulically-operated grille-like lid |
| US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4588684A (en) | 1983-04-26 | 1986-05-13 | Chiron Corporation | a-Factor and its processing signals |
| IE930961L (en) | 1984-07-06 | 1986-01-06 | Sandoz Ag | Lymphokine production and purification |
| ATE78515T1 (de) | 1984-10-05 | 1992-08-15 | Genentech Inc | Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung. |
| US6069229A (en) * | 1997-03-07 | 2000-05-30 | Schering Corporation | Mammalian proteinases; oxidoreductases; related reagents |
| AU8513198A (en) * | 1997-07-25 | 1999-02-16 | Du Pont Pharmaceuticals Company | Aggrecan degrading metallo proteases |
| US6842704B2 (en) * | 1998-02-04 | 2005-01-11 | Immunex Corporation | Crystalline TNF-α-converting enzyme and uses thereof |
| WO2000053774A2 (en) * | 1999-03-08 | 2000-09-14 | Neurocrine Biosciences, Inc. | Metalloproteinases and methods of use therefor |
| US6391610B1 (en) * | 1999-08-06 | 2002-05-21 | The Cleveland Clinic Foundation | Nucleic acids encoding zinc metalloproteases |
| EP1136547A3 (en) * | 2000-03-22 | 2002-09-25 | Pfizer Products Inc. | Adamts polypeptides, nucleic acids encoding them, and uses thereof |
| US6458552B1 (en) * | 2000-06-06 | 2002-10-01 | Ortho-Mcneil Pharmaceutical, Inc. | Metalloprotease peptide substrates and methods |
| US20020151702A1 (en) * | 2000-10-18 | 2002-10-17 | Genetics Institute, Inc. | Aggrecanase molecules |
| SE0102298D0 (sv) * | 2001-06-27 | 2001-06-27 | Astrazeneca Ab | Crystal structure of enzyme and uses thereof |
| PL367675A1 (en) * | 2001-07-05 | 2005-03-07 | Wyeth | Aggrecanase molecules |
| US7037658B2 (en) | 2001-08-16 | 2006-05-02 | Regents Of University Of Michigan | Methods and compositions for detecting variant ADAMTS13 genes |
| US20030105313A1 (en) * | 2001-10-16 | 2003-06-05 | American Home Products Corporation | Aggrecanase molecules |
| KR20040077928A (ko) * | 2002-01-31 | 2004-09-07 | 와이어쓰 | 아그레카나제 분자 |
| WO2003066822A2 (en) * | 2002-02-05 | 2003-08-14 | Wyeth | Truncated aggrecanase molecules |
| AU2003261269A1 (en) * | 2002-07-29 | 2004-02-16 | Wyeth | Modified adamts4 molecules and method of use thereof |
-
2003
- 2003-07-29 AU AU2003261269A patent/AU2003261269A1/en not_active Withdrawn
- 2003-07-29 EP EP03771941A patent/EP1525307A2/en not_active Withdrawn
- 2003-07-29 JP JP2004524915A patent/JP2005534308A/ja active Pending
- 2003-07-29 MX MXPA05000959A patent/MXPA05000959A/es unknown
- 2003-07-29 WO PCT/US2003/023484 patent/WO2004011637A2/en not_active Ceased
- 2003-07-29 CA CA002492444A patent/CA2492444A1/en not_active Withdrawn
- 2003-07-29 BR BRPI0313083-5A patent/BR0313083A/pt not_active IP Right Cessation
- 2003-07-29 US US10/628,432 patent/US7118902B2/en not_active Expired - Fee Related
- 2003-07-29 CN CNA038184230A patent/CN1681920A/zh not_active Withdrawn
-
2005
- 2005-01-27 IL IL16653505A patent/IL166535A0/xx unknown
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2006
- 2006-06-12 US US11/451,006 patent/US20060228354A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003261269A1 (en) | 2004-02-16 |
| US7118902B2 (en) | 2006-10-10 |
| WO2004011637A3 (en) | 2004-04-08 |
| IL166535A0 (en) | 2006-01-15 |
| WO2004011637A2 (en) | 2004-02-05 |
| CN1681920A (zh) | 2005-10-12 |
| US20060228354A1 (en) | 2006-10-12 |
| US20040142863A1 (en) | 2004-07-22 |
| BR0313083A (pt) | 2007-07-17 |
| EP1525307A2 (en) | 2005-04-27 |
| CA2492444A1 (en) | 2004-02-05 |
| JP2005534308A (ja) | 2005-11-17 |
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