JP2005532254A5 - - Google Patents

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Publication number
JP2005532254A5
JP2005532254A5 JP2003541765A JP2003541765A JP2005532254A5 JP 2005532254 A5 JP2005532254 A5 JP 2005532254A5 JP 2003541765 A JP2003541765 A JP 2003541765A JP 2003541765 A JP2003541765 A JP 2003541765A JP 2005532254 A5 JP2005532254 A5 JP 2005532254A5
Authority
JP
Japan
Prior art keywords
uridine
tetraphosphate
triphosphate
alkyl
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003541765A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005532254A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/035775 external-priority patent/WO2003039473A2/en
Publication of JP2005532254A publication Critical patent/JP2005532254A/ja
Publication of JP2005532254A5 publication Critical patent/JP2005532254A5/ja
Pending legal-status Critical Current

Links

JP2003541765A 2001-11-06 2002-11-06 炎症性疾患を治療又は予防する方法 Pending JP2005532254A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33782801P 2001-11-06 2001-11-06
PCT/US2002/035775 WO2003039473A2 (en) 2001-11-06 2002-11-06 Method for treating or preventing inflammatory diseases

Publications (2)

Publication Number Publication Date
JP2005532254A JP2005532254A (ja) 2005-10-27
JP2005532254A5 true JP2005532254A5 (enExample) 2006-01-05

Family

ID=23322192

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003541765A Pending JP2005532254A (ja) 2001-11-06 2002-11-06 炎症性疾患を治療又は予防する方法

Country Status (11)

Country Link
US (1) US7256183B2 (enExample)
EP (1) EP1450820A4 (enExample)
JP (1) JP2005532254A (enExample)
KR (1) KR20050043761A (enExample)
CN (1) CN1612739A (enExample)
AR (1) AR037263A1 (enExample)
BR (1) BR0213897A (enExample)
CA (1) CA2465894A1 (enExample)
MX (1) MXPA04004215A (enExample)
TW (1) TW200300692A (enExample)
WO (1) WO2003039473A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003028712A2 (en) * 2001-09-28 2003-04-10 Universite Libre De Bruxelles Purinergic and pyrimidinergic receptor agonists for the treatment of activated cd4+ t lymphocyte-mediated immune diseases
US20060177517A1 (en) * 2003-02-26 2006-08-10 Toshikazu Shiba Antiinflammtory agent and antiinflammatory medical material
GB0417886D0 (en) * 2004-08-11 2004-09-15 Univ Cardiff Method and means for enhanced pulmonary delivery
SE529064C2 (sv) * 2005-01-03 2007-04-24 Selectica Pharmaceuticals Ab Topiska kompositioner
GB0502250D0 (en) * 2005-02-03 2005-03-09 Ic Vec Ltd Use
WO2007041495A2 (en) * 2005-09-29 2007-04-12 University Of California, San Diego Dampening humoral and innate immunity by inhibition of ppgalnact-1
US8618074B2 (en) * 2007-03-15 2013-12-31 Board Of Regents Of The University Of Texas System GPCR enhanced neuroprotection to treat brain injury
US8168597B2 (en) * 2008-10-22 2012-05-01 Inspire Pharmaceuticals, Inc. Method for treating cystic fibrosis
GB201209244D0 (en) * 2012-05-25 2012-07-04 Globalacorn Ltd Compositions
US10111904B2 (en) * 2013-01-09 2018-10-30 Berlock Aps Micron-sized gold, kit comprising said gold and its use as a non-toxic immune suppressor
US20150031712A1 (en) * 2013-03-12 2015-01-29 Moshe Rogosnitzky Therapeutic Compositions Containing Dipyridamole and Treatment Packs Including Such Compositions and Methods for Producing Same
GB201320962D0 (en) * 2013-11-27 2014-01-08 Globalacorn Ltd Compositions
GB201320959D0 (en) * 2013-11-27 2014-01-08 Globalacorn Ltd Compositions

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292498A (en) 1991-06-19 1994-03-08 The University Of North Carolina At Chapel Hill Method of treating lung disease with uridine triphosphates
US6255059B1 (en) 1993-03-31 2001-07-03 Cadus Pharmaceutical Corporation Methods for identifying G protein coupled receptor effectors
US5656256A (en) 1994-12-14 1997-08-12 The University Of North Carolina At Chapel Hill Methods of treating lung disease by an aerosol containing benzamil or phenamil
US6147056A (en) * 1995-06-06 2000-11-14 Trustees Of Boston University Use of locally applied DNA fragments
US5635160A (en) 1995-06-07 1997-06-03 The University Of North Carolina At Chapel Hill Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
US5628984A (en) 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
US6423694B1 (en) 1996-02-21 2002-07-23 Inspire Pharmaceuticals, Inc. Method of treating otitis media with uridine triphosphates and related compounds
US5900407A (en) 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
AU727314B2 (en) 1996-03-27 2000-12-07 Inspire Pharmaceuticals, Inc. Method of treating ciliary dyskinesia with uridine triphosphates and related compounds
US5837861A (en) 1997-02-10 1998-11-17 Inspire Pharmaceuticals, Inc. Dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency
US5789391A (en) 1996-07-03 1998-08-04 Inspire Pharmaceuticals, Inc. Method of treating sinusitis with uridine triphosphates and related compounds
US5968913A (en) 1996-07-03 1999-10-19 Inspire Pharmaceuticals, Inc. Pharmaceutical compositions of uridine triphosphate
US5763447C1 (en) 1996-07-23 2002-05-07 Inspire Pharmaceuticals Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds
WO1998015835A1 (en) 1996-10-08 1998-04-16 Inspire Pharmaceuticals, Inc. Method of early lung cancer detection via sputum induction and analysis of sputum to detect cancer associated substances
EP0929218A4 (en) * 1996-10-30 2001-05-16 Univ North Carolina P2Y RECEPTOR ANTAGONISTS
US6159952A (en) 1996-11-07 2000-12-12 Inspire Pharmaceuticals, Inc. Method of treating bronchitis with uridine triphosphate and related compounds
ES2264197T3 (es) * 1997-02-06 2006-12-16 Inspire Pharmaceuticals, Inc. Dinucleotidos y sus usos.
US6372724B1 (en) * 1997-03-25 2002-04-16 Duska Scientific Co. Modulation of human mast cell activation
US6462028B2 (en) 1997-07-25 2002-10-08 Inspire Pharmaceuticals, Inc. Method of promoting cervical and vaginal secretions
US6143279A (en) * 1997-08-29 2000-11-07 The University Of North Carolina At Chapel Hill Uridine 5'-diphosphate and analogs useful for treating lung diseases
JP4633927B2 (ja) * 1998-05-22 2011-02-16 インスパイアー ファーマシューティカルズ,インコーポレイティド 治療用ジヌクレオチドおよび誘導体
US6264975B1 (en) * 1998-10-20 2001-07-24 The University Of North Carolina At Chapel Hill Methods of hydrating mucosal surfaces
WO2000050024A2 (en) * 1999-02-26 2000-08-31 Inspire Pharmaceuticals, Inc. Method of promoting mucosal hydration with certain uridine, adenine and cytidine diphosphates and analogs thereof
CN1413113A (zh) * 1999-12-22 2003-04-23 印斯拜尔药品股份有限公司 使用嘌呤能受体激动剂治疗胃肠道疾病的方法
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline
EP1432426A2 (en) * 2001-09-05 2004-06-30 ACTIAL Farmaceutica Lda. USE OF UNMETHYLATED CpG

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