JP2005529610A5 - - Google Patents

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Publication number
JP2005529610A5
JP2005529610A5 JP2004513497A JP2004513497A JP2005529610A5 JP 2005529610 A5 JP2005529610 A5 JP 2005529610A5 JP 2004513497 A JP2004513497 A JP 2004513497A JP 2004513497 A JP2004513497 A JP 2004513497A JP 2005529610 A5 JP2005529610 A5 JP 2005529610A5
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JP
Japan
Prior art keywords
polypeptide
polypeptide expression
interest
functional
sequence
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JP2004513497A
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English (en)
Japanese (ja)
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JP4647309B2 (ja
JP2005529610A (ja
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Priority claimed from PCT/NL2003/000432 external-priority patent/WO2003106684A2/en
Publication of JP2005529610A publication Critical patent/JP2005529610A/ja
Publication of JP2005529610A5 publication Critical patent/JP2005529610A5/ja
Application granted granted Critical
Publication of JP4647309B2 publication Critical patent/JP4647309B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004513497A 2002-06-14 2003-06-13 複数のタンパク質の同時生産のための方法；そこで使用するためのベクター及び細胞 Expired - Fee Related JP4647309B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02077350 2002-06-14
PCT/NL2003/000432 WO2003106684A2 (en) 2002-06-14 2003-06-13 A method for simultaneous production of multiple proteins; vectors and cells for use therein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009184727A Division JP5095690B2 (ja) 2002-06-14 2009-08-07 複数のタンパク質の同時生産のための方法；そこで使用するためのベクター及び細胞

Publications (3)

Publication Number Publication Date
JP2005529610A JP2005529610A (ja) 2005-10-06
JP2005529610A5 true JP2005529610A5 (https=) 2006-08-03
JP4647309B2 JP4647309B2 (ja) 2011-03-09

Family

ID=29724494

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2004513497A Expired - Fee Related JP4647309B2 (ja) 2002-06-14 2003-06-13 複数のタンパク質の同時生産のための方法；そこで使用するためのベクター及び細胞
JP2009184727A Expired - Fee Related JP5095690B2 (ja) 2002-06-14 2009-08-07 複数のタンパク質の同時生産のための方法；そこで使用するためのベクター及び細胞
JP2009203428A Expired - Fee Related JP5095693B2 (ja) 2002-06-14 2009-09-03 複数のタンパク質の同時生産のための方法；そこで使用するためのベクター及び細胞

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009184727A Expired - Fee Related JP5095690B2 (ja) 2002-06-14 2009-08-07 複数のタンパク質の同時生産のための方法；そこで使用するためのベクター及び細胞
JP2009203428A Expired - Fee Related JP5095693B2 (ja) 2002-06-14 2009-09-03 複数のタンパク質の同時生産のための方法；そこで使用するためのベクター及び細胞

Country Status (11)

Country Link
US (3) US7364878B2 (https=)
EP (1) EP1513937B1 (https=)
JP (3) JP4647309B2 (https=)
AT (1) ATE500331T1 (https=)
AU (1) AU2003238719B2 (https=)
CA (3) CA2489475C (https=)
DE (1) DE60336228D1 (https=)
DK (1) DK1513937T3 (https=)
ES (1) ES2362273T3 (https=)
NZ (1) NZ537073A (https=)
WO (1) WO2003106684A2 (https=)

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WO2004106375A1 (en) 2003-05-30 2004-12-09 Merus Biopharmaceuticals B.V. I.O. Fab library for the preparation of anti vegf and anti rabies virus fabs
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
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KR101271884B1 (ko) * 2004-11-08 2013-06-05 크로마제닉스 비.브이. 고수준으로 단백질을 발현하는 숙주세포의 선택
US8999667B2 (en) 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
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US20100136616A1 (en) * 2004-11-08 2010-06-03 Chromagenics B.V. Selection of Host Cells Expressing Protein at High Levels
ES2384391T3 (es) 2004-11-08 2012-07-04 Chromagenics B.V. Selección de células hospedantes que expresan proteína a altos niveles
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EP2443239B1 (en) 2009-06-15 2015-11-25 Cellagenics B.V. Novel stringent selectable markers
US8497105B2 (en) 2009-06-26 2013-07-30 Cobalt Technologies, Inc. Integrated system and process for bioproduct production
WO2011159157A1 (en) 2010-06-15 2011-12-22 Cellagenics B.V. Novel intergenic elements for enhancing gene expression
DK2611915T3 (da) 2010-09-01 2015-06-22 Cellagenics B V Nukleinsyrefragmenter fra en ribosomal proteinpromoter til forstærkning af genekspression
US9617329B2 (en) 2010-10-01 2017-04-11 Csl Limited Method of cloning nucleic acid
WO2013078433A1 (en) 2011-11-23 2013-05-30 University Of Hawaii Auto-processing domains for polypeptide expression
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WO2003106674A2 (en) * 2002-06-14 2003-12-24 Chromagenics B.V. Means and methods for regulating gene expression
ATE524559T1 (de) 2002-12-18 2011-09-15 Chromagenics Bv Methode zur verbesserung der proteinproduktion
ATE354645T1 (de) 2002-12-20 2007-03-15 Chromagenics Bv Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können
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