JP2005529340A - 湿った環境中の走査型電子顕微鏡のための低圧チャンバー - Google Patents
湿った環境中の走査型電子顕微鏡のための低圧チャンバー Download PDFInfo
- Publication number
- JP2005529340A JP2005529340A JP2004511866A JP2004511866A JP2005529340A JP 2005529340 A JP2005529340 A JP 2005529340A JP 2004511866 A JP2004511866 A JP 2004511866A JP 2004511866 A JP2004511866 A JP 2004511866A JP 2005529340 A JP2005529340 A JP 2005529340A
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- JP
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- Prior art keywords
- specimen
- enclosure
- assembly
- pressure
- volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012530 fluid Substances 0.000 claims abstract description 111
- 239000007788 liquid Substances 0.000 claims abstract description 74
- 238000010894 electron beam technology Methods 0.000 claims abstract description 28
- 239000000523 sample Substances 0.000 description 42
- 239000000853 adhesive Substances 0.000 description 12
- 230000001070 adhesive effect Effects 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 8
- 239000004926 polymethyl methacrylate Substances 0.000 description 8
- 238000000386 microscopy Methods 0.000 description 6
- 238000001704 evaporation Methods 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 238000004113 cell culture Methods 0.000 description 4
- 229920001721 polyimide Polymers 0.000 description 4
- 239000004642 Polyimide Substances 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
Images
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J37/00—Discharge tubes with provision for introducing objects or material to be exposed to the discharge, e.g. for the purpose of examination or processing thereof
- H01J37/02—Details
- H01J37/20—Means for supporting or positioning the object or the material; Means for adjusting diaphragms or lenses associated with the support
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J2237/00—Discharge tubes exposing object to beam, e.g. for analysis treatment, etching, imaging
- H01J2237/20—Positioning, supporting, modifying or maintaining the physical state of objects being observed or treated
- H01J2237/2002—Controlling environment of sample
- H01J2237/2003—Environmental cells
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J2237/00—Discharge tubes exposing object to beam, e.g. for analysis treatment, etching, imaging
- H01J2237/26—Electron or ion microscopes
- H01J2237/2602—Details
- H01J2237/2605—Details operating at elevated pressures, e.g. atmosphere
- H01J2237/2608—Details operating at elevated pressures, e.g. atmosphere with environmental specimen chamber
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Sampling And Sample Adjustment (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL15005602A IL150056A0 (en) | 2002-06-05 | 2002-06-05 | Low-pressure chamber for scanning electron microscopy in a wet environment |
| PCT/IL2003/000455 WO2003104847A2 (en) | 2002-06-05 | 2003-06-01 | Low-pressure chamber for scanning electron microscopy in a wet environment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005529340A true JP2005529340A (ja) | 2005-09-29 |
| JP2005529340A5 JP2005529340A5 (https=) | 2006-07-20 |
Family
ID=28053348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004511866A Pending JP2005529340A (ja) | 2002-06-05 | 2003-06-01 | 湿った環境中の走査型電子顕微鏡のための低圧チャンバー |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7304313B2 (https=) |
| EP (1) | EP1509941A4 (https=) |
| JP (1) | JP2005529340A (https=) |
| AU (1) | AU2003228091A1 (https=) |
| IL (1) | IL150056A0 (https=) |
| WO (1) | WO2003104847A2 (https=) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007292702A (ja) * | 2006-04-27 | 2007-11-08 | Jeol Ltd | 試料検査装置及び試料検査方法並びに試料検査システム |
| JP2008016249A (ja) * | 2006-07-04 | 2008-01-24 | Jeol Ltd | 試料保持体、試料検査方法及び試料検査装置並びに試料検査システム |
| JP2008032531A (ja) * | 2006-07-28 | 2008-02-14 | Kao Corp | 細菌の共凝集能の評価方法 |
| WO2009133842A1 (ja) | 2008-04-28 | 2009-11-05 | 株式会社日立ハイテクノロジーズ | 透過型電子顕微鏡、及び試料観察方法 |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003104846A2 (en) * | 2002-06-05 | 2003-12-18 | Quantomix Ltd. | A sample enclosure for a scanning electron microscope and methods of use thereof |
| WO2006021961A2 (en) * | 2004-08-26 | 2006-03-02 | Quantomix Ltd. | Sample enclosure for inspection and methods of use thereof |
| TWI275118B (en) * | 2005-12-09 | 2007-03-01 | Li Bing Huan | Sample box of electron microscope for observing a general sample/live cell |
| GR1005943B (el) * | 2006-05-15 | 2008-06-19 | Γ. Παπανικολαου & Σια Ε.Ε. | Τρυβλιο μικροσκοπιου με στερεωμενη αντικειμενοφορο πλακα και με στεγανοποιητικο καλυμμα καθως και διαταξη για τη στερεωση βασης συστοιχιας σωληναριωνμικροβιολογικων εξετασεων. |
| EP1953793B1 (en) * | 2007-01-31 | 2012-05-16 | JEOL Ltd. | Specimen holder, specimen inspection apparatus, specimen inspection method, and method of fabricating specimen holder |
| US8059271B2 (en) | 2009-02-04 | 2011-11-15 | The United States Of America As Represented By The Secretary Of The Army | Reusable sample holding device permitting ready loading of very small wet samples |
| US8698098B2 (en) | 2010-07-30 | 2014-04-15 | E.A. Fischione Instruments, Inc. | In situ holder assembly |
| US8178851B2 (en) | 2010-07-30 | 2012-05-15 | E.A. Fischione Instruments, Inc. | In situ holder assembly |
| WO2012018827A2 (en) * | 2010-08-02 | 2012-02-09 | Protochips, Inc. | Electron microscope sample holder for forming a gas or liquid cell with two semiconductor devices |
| US9437393B2 (en) | 2012-11-16 | 2016-09-06 | Protochips, Inc. | Method for forming an electrical connection to an sample support in an electron microscope holder |
| JP6364167B2 (ja) * | 2013-09-30 | 2018-07-25 | 株式会社日立ハイテクノロジーズ | 環境制御型荷電粒子観察システム |
| GB2537579A (en) * | 2014-11-07 | 2016-10-26 | Linkam Scient Instr Ltd | Microscopic sample preparation |
| WO2017006408A1 (ja) * | 2015-07-06 | 2017-01-12 | 株式会社 日立ハイテクノロジーズ | 荷電粒子線装置 |
| CN209591971U (zh) * | 2018-03-22 | 2019-11-05 | 邑流微测股份有限公司 | 显微镜 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1345670A (fr) | 1962-10-25 | 1963-12-13 | Radiologie Cie Gle | Perfectionnements aux porte-échantillons liquides pour spectromètres à rayons chious vide |
| US3657596A (en) | 1965-05-20 | 1972-04-18 | Westinghouse Electric Corp | Electron image device having target comprising porous region adjacent conductive layer and outer, denser region |
| US3378684A (en) | 1965-06-16 | 1968-04-16 | Gen Electric | Fluid sample cell with means to keep constant pressure on the sample fluid |
| HU168264B (https=) * | 1974-03-28 | 1976-03-28 | ||
| US4071766A (en) * | 1974-03-28 | 1978-01-31 | Mta Kozponti Kemiai Kutato Intezet | Micro-chamber for electron optical examinations particularly for the electron microscopic examination of biological objects |
| JPS5168585U (https=) | 1974-11-26 | 1976-05-31 | ||
| US4115689A (en) | 1977-07-06 | 1978-09-19 | Won Vann Y | Leveling device for forming X-ray specimen |
| DE2921151C2 (de) | 1979-05-25 | 1982-12-02 | Ernst Leitz Wetzlar Gmbh, 6330 Wetzlar | Vorrichtung zum Nachweis von in einem Abtast-Elektronenstrahlmikroskop von einer Probe ausgehenden Rückstreuelektronen |
| AU534811B2 (en) | 1979-07-03 | 1984-02-16 | Unisearch Limited | Atmospheric scanning electron microscope |
| US4448311A (en) | 1983-01-24 | 1984-05-15 | Tech Ref, Inc. | Sample cell |
| JPS59168652A (ja) | 1983-03-16 | 1984-09-22 | Hitachi Ltd | 素子修正方法及びその装置 |
| US4618938A (en) | 1984-02-22 | 1986-10-21 | Kla Instruments Corporation | Method and apparatus for automatic wafer inspection |
| US4587666A (en) | 1984-05-03 | 1986-05-06 | Angelo M. Torrisi | System and a method for mounting film to a sample holder for X-ray spectroscopic fluorescence analysis |
| US4720622A (en) | 1985-03-11 | 1988-01-19 | Sanyo Electric Co., Ltd | Wall-mounted type cooking apparatus |
| US4705949A (en) * | 1985-11-25 | 1987-11-10 | The United States Of America As Represented By The Secretary Of Commerce | Method and apparatus relating to specimen cells for scanning electron microscopes |
| US4720633A (en) | 1986-01-17 | 1988-01-19 | Electro-Scan Corporation | Scanning electron microscope for visualization of wet samples |
| WO1988001099A1 (en) | 1986-08-01 | 1988-02-11 | Electro-Scan Corporation | Multipurpose gaseous detector device for electron microscopes |
| US4880976A (en) | 1987-05-21 | 1989-11-14 | Electroscan Corporation | Secondary electron detector for use in a gaseous atmosphere |
| US5250808A (en) | 1987-05-21 | 1993-10-05 | Electroscan Corporation | Integrated electron optical/differential pumping/imaging signal system for an environmental scanning electron microscope |
| US4929041A (en) | 1989-01-09 | 1990-05-29 | Johnston Pump/General Valve, Inc. | Cathodoluminescence system for use in a scanning electron microscope including means for controlling optical fiber aperture |
| US5103102A (en) | 1989-02-24 | 1992-04-07 | Micrion Corporation | Localized vacuum apparatus and method |
| JP2794471B2 (ja) * | 1989-11-24 | 1998-09-03 | 日本電子テクニクス株式会社 | 電子顕微鏡 |
| US5866904A (en) | 1990-10-12 | 1999-02-02 | Hitachi, Ltd. | Scanning electron microscope and method for dimension measuring by using the same |
| JP3148353B2 (ja) | 1991-05-30 | 2001-03-19 | ケーエルエー・インストルメンツ・コーポレーション | 電子ビーム検査方法とそのシステム |
| US5122663A (en) | 1991-07-24 | 1992-06-16 | International Business Machine Corporation | Compact, integrated electron beam imaging system |
| US5323441A (en) | 1992-12-15 | 1994-06-21 | Angelo M. Torrisi | Sample holder for spectroscopic analysis and method for mounting film to sample holder |
| JP2781320B2 (ja) * | 1993-01-18 | 1998-07-30 | 株式会社蛋白工学研究所 | 電子顕微鏡等の試料ホルダ |
| US5326971A (en) | 1993-05-17 | 1994-07-05 | Motorola, Inc. | Transmission electron microscope environmental specimen holder |
| US5412211A (en) | 1993-07-30 | 1995-05-02 | Electroscan Corporation | Environmental scanning electron microscope |
| US5362964A (en) | 1993-07-30 | 1994-11-08 | Electroscan Corporation | Environmental scanning electron microscope |
| US5466940A (en) | 1994-06-20 | 1995-11-14 | Opal Technologies Ltd. | Electron detector with high backscattered electron acceptance for particle beam apparatus |
| US5644132A (en) | 1994-06-20 | 1997-07-01 | Opan Technologies Ltd. | System for high resolution imaging and measurement of topographic and material features on a specimen |
| US6025592A (en) | 1995-08-11 | 2000-02-15 | Philips Electronics North America | High temperature specimen stage and detector for an environmental scanning electron microscope |
| US5898261A (en) * | 1996-01-31 | 1999-04-27 | The United States Of America As Represented By The Secretary Of The Air Force | Fluid-cooled particle-beam transmission window |
| US5667791A (en) | 1996-05-31 | 1997-09-16 | Thione International, Inc. | X-ray induced skin damage protective composition |
| JPH1064467A (ja) | 1996-08-23 | 1998-03-06 | Toshiba Corp | 電子顕微鏡 |
| GB9623768D0 (en) | 1996-11-15 | 1997-01-08 | Leo Electron Microscopy Limite | Scanning electron microscope |
| JP3500264B2 (ja) | 1997-01-29 | 2004-02-23 | 株式会社日立製作所 | 試料分析装置 |
| US5859699A (en) | 1997-02-07 | 1999-01-12 | Arcturus Engineering, Inc. | Laser capture microdissection analysis vessel |
| JPH10241620A (ja) * | 1997-02-27 | 1998-09-11 | Nikon Corp | 環境制御型走査型電子顕微鏡 |
| US5789748A (en) | 1997-05-29 | 1998-08-04 | Stanford University | Low voltage electron beam system |
| JPH1167133A (ja) * | 1997-08-20 | 1999-03-09 | Nikon Corp | 環境制御型走査型電子顕微鏡 |
| US5945672A (en) | 1998-01-29 | 1999-08-31 | Fei Company | Gaseous backscattered electron detector for an environmental scanning electron microscope |
| JP3688202B2 (ja) * | 1998-05-22 | 2005-08-24 | ユーロ−セルティーク エス.エイ. | 環境走査電子顕微鏡の溶解ステージ |
| US6452177B1 (en) | 1998-09-04 | 2002-09-17 | California Institute Of Technology | Atmospheric electron x-ray spectrometer |
| AU2001280075A1 (en) | 2000-08-17 | 2002-02-25 | El-Mul Technologies Ltd. | Method of identification and quantification of biological molecules and apparatus therefore |
| AU2002221019B2 (en) | 2000-12-01 | 2007-02-08 | El-Mul Technologies Ltd. | Device and method for the examination of samples in a non-vacuum environment using a scanning electron microscope |
| WO2003104846A2 (en) * | 2002-06-05 | 2003-12-18 | Quantomix Ltd. | A sample enclosure for a scanning electron microscope and methods of use thereof |
| EP1595265A1 (en) | 2003-02-20 | 2005-11-16 | Quantomix Ltd. | A sample enclosure for a scanning electron microscope and methods of use thereof |
-
2002
- 2002-06-05 IL IL15005602A patent/IL150056A0/xx unknown
-
2003
- 2003-06-01 JP JP2004511866A patent/JP2005529340A/ja active Pending
- 2003-06-01 WO PCT/IL2003/000455 patent/WO2003104847A2/en not_active Ceased
- 2003-06-01 EP EP03725573A patent/EP1509941A4/en not_active Withdrawn
- 2003-06-01 US US10/516,407 patent/US7304313B2/en not_active Expired - Fee Related
- 2003-06-01 AU AU2003228091A patent/AU2003228091A1/en not_active Abandoned
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007292702A (ja) * | 2006-04-27 | 2007-11-08 | Jeol Ltd | 試料検査装置及び試料検査方法並びに試料検査システム |
| JP2008016249A (ja) * | 2006-07-04 | 2008-01-24 | Jeol Ltd | 試料保持体、試料検査方法及び試料検査装置並びに試料検査システム |
| JP2008032531A (ja) * | 2006-07-28 | 2008-02-14 | Kao Corp | 細菌の共凝集能の評価方法 |
| WO2009133842A1 (ja) | 2008-04-28 | 2009-11-05 | 株式会社日立ハイテクノロジーズ | 透過型電子顕微鏡、及び試料観察方法 |
| US8785883B2 (en) | 2008-04-28 | 2014-07-22 | Hitachi High-Technologies Corporation | Transmission electron microscope, and method of observing specimen |
| EP2801998A2 (en) | 2008-04-28 | 2014-11-12 | Hitachi High-Technologies Corporation | Transmission electron microscope, and method of observing specimen |
| US9129772B2 (en) | 2008-04-28 | 2015-09-08 | Hitachi High-Technologies Corporation | Transmission electron microscope, and method of observing specimen |
Also Published As
| Publication number | Publication date |
|---|---|
| US20050279938A1 (en) | 2005-12-22 |
| EP1509941A2 (en) | 2005-03-02 |
| WO2003104847A2 (en) | 2003-12-18 |
| IL150056A0 (en) | 2002-12-01 |
| US7304313B2 (en) | 2007-12-04 |
| WO2003104847A3 (en) | 2004-04-15 |
| AU2003228091A1 (en) | 2003-12-22 |
| AU2003228091A8 (en) | 2003-12-22 |
| EP1509941A4 (en) | 2007-12-12 |
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