JP2005528894A5 - - Google Patents
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- Publication number
- JP2005528894A5 JP2005528894A5 JP2003584089A JP2003584089A JP2005528894A5 JP 2005528894 A5 JP2005528894 A5 JP 2005528894A5 JP 2003584089 A JP2003584089 A JP 2003584089A JP 2003584089 A JP2003584089 A JP 2003584089A JP 2005528894 A5 JP2005528894 A5 JP 2005528894A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- receptor
- sample
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 238000000034 method Methods 0.000 claims 14
- 229920001184 polypeptide Polymers 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 6
- 239000000556 agonist Substances 0.000 claims 6
- 239000005557 antagonist Substances 0.000 claims 6
- 229910052791 calcium Inorganic materials 0.000 claims 6
- 239000011575 calcium Substances 0.000 claims 6
- 239000003446 ligand Substances 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 102000005962 receptors Human genes 0.000 claims 6
- 108020003175 receptors Proteins 0.000 claims 6
- 230000000890 antigenic effect Effects 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 238000013508 migration Methods 0.000 claims 2
- 230000005012 migration Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims 1
- 230000027425 release of sequestered calcium ion into cytosol Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37264002P | 2002-04-12 | 2002-04-12 | |
| PCT/US2003/011159 WO2003087134A2 (en) | 2002-04-12 | 2003-04-10 | G-protein coupled receptor ligands and methods |
Related Child Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006103683A Division JP2006254916A (ja) | 2002-04-12 | 2006-04-04 | Ｇタンパク質共役レセプターリガンドおよび方法 |
| JP2010163440A Division JP2010252805A (ja) | 2002-04-12 | 2010-07-20 | Ｇタンパク質共役レセプターリガンドおよび方法 |
| JP2010163439A Division JP5284313B2 (ja) | 2002-04-12 | 2010-07-20 | Ｇタンパク質共役レセプターリガンドおよび方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005528894A JP2005528894A (ja) | 2005-09-29 |
| JP2005528894A5 true JP2005528894A5 (https=) | 2006-07-06 |
| JP4594623B2 JP4594623B2 (ja) | 2010-12-08 |
Family
ID=29250884
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003584089A Expired - Fee Related JP4594623B2 (ja) | 2002-04-12 | 2003-04-10 | Ｇタンパク質共役レセプターリガンドおよび方法 |
| JP2006103683A Pending JP2006254916A (ja) | 2002-04-12 | 2006-04-04 | Ｇタンパク質共役レセプターリガンドおよび方法 |
| JP2010163440A Withdrawn JP2010252805A (ja) | 2002-04-12 | 2010-07-20 | Ｇタンパク質共役レセプターリガンドおよび方法 |
| JP2010163439A Expired - Fee Related JP5284313B2 (ja) | 2002-04-12 | 2010-07-20 | Ｇタンパク質共役レセプターリガンドおよび方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006103683A Pending JP2006254916A (ja) | 2002-04-12 | 2006-04-04 | Ｇタンパク質共役レセプターリガンドおよび方法 |
| JP2010163440A Withdrawn JP2010252805A (ja) | 2002-04-12 | 2010-07-20 | Ｇタンパク質共役レセプターリガンドおよび方法 |
| JP2010163439A Expired - Fee Related JP5284313B2 (ja) | 2002-04-12 | 2010-07-20 | Ｇタンパク質共役レセプターリガンドおよび方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7338772B2 (https=) |
| EP (1) | EP1532446B1 (https=) |
| JP (4) | JP4594623B2 (https=) |
| CN (1) | CN1324047C (https=) |
| AT (1) | ATE545866T1 (https=) |
| AU (1) | AU2003221878A1 (https=) |
| CA (1) | CA2481508A1 (https=) |
| MX (1) | MXPA04009959A (https=) |
| WO (1) | WO2003087134A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04009959A (es) | 2002-04-12 | 2004-12-13 | Schering Corp | Ligandos del receptor acoplado a la proteina g y metodos. |
| WO2006039256A1 (en) * | 2004-09-29 | 2006-04-13 | Glaxo Group Limited | Use of gpr103 agonists for modulating feeding behaviour |
| WO2009043524A2 (en) * | 2007-09-11 | 2009-04-09 | Mondobiotech Laboratories Ag | Use of a peptide as therapeutic agent |
| JP5313068B2 (ja) * | 2009-03-09 | 2013-10-09 | 富士フイルム株式会社 | 側視内視鏡装置 |
| EP3207052B1 (en) * | 2014-10-14 | 2020-09-30 | Université de Montréal | Biosensor based on gbetagamma-interacting proteins to monitor g-protein activation |
| JP6405352B2 (ja) * | 2016-09-16 | 2018-10-17 | 株式会社Ｓｕｂａｒｕ | 直噴内燃機関のピストン |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4952496A (en) | 1984-03-30 | 1990-08-28 | Associated Universities, Inc. | Cloning and expression of the gene for bacteriophage T7 RNA polymerase |
| US5693489A (en) | 1984-03-30 | 1997-12-02 | Associated Universities, Inc. | Cloning and expression of the gene for bacteriophage T7 RNA polymerase |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US5011912A (en) * | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| CN1167490A (zh) * | 1994-11-10 | 1997-12-10 | 人体基因组科学有限公司 | 人司登尼亚钙蛋白-α |
| DE69733649T2 (de) | 1996-04-09 | 2006-05-18 | NPS Pharmaceuticals, Inc., Salt Lake City | Calcylitische verbindungen |
| SE9704836D0 (sv) | 1997-12-22 | 1997-12-22 | Astra Pharma Inc | Novel receptor |
| WO2000011015A1 (en) | 1998-08-24 | 2000-03-02 | Alphagene, Inc. | Secreted proteins and polynucleotides encoding them |
| KR20010080882A (ko) * | 1998-10-13 | 2001-08-25 | 리처드 피. 버군 쥬니어 | 구성적으로 활성화된 비내생성 인간 ｇ 단백질 결합형수용체 |
| US6852836B1 (en) | 1998-11-20 | 2005-02-08 | Chugai Sieyaku Kabushiki Kaisha | Gene encoding brain-specific membrane protein |
| DK1584683T3 (da) | 1998-11-20 | 2007-10-29 | Arena Pharm Inc | Human G-protein-koblet orphan receptor RUP3 |
| JP2002543147A (ja) | 1999-04-29 | 2002-12-17 | ノボ ノルディスク アクティーゼルスカブ | ブラジキニン放出の阻害におけるヘパリン結合アンタゴニストの使用 |
| WO2000078809A1 (en) * | 1999-06-21 | 2000-12-28 | Smithkline Beecham Corporation | Axor16, a g protein coupled receptor |
| CA2311201A1 (en) * | 1999-08-05 | 2001-02-05 | Genset S.A. | Ests and encoded human proteins |
| AU6727900A (en) * | 1999-08-27 | 2001-03-26 | Takeda Chemical Industries Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| WO2001025277A1 (en) * | 1999-10-07 | 2001-04-12 | Maxygen Aps | Single-chain antagonist polypeptides |
| WO2001048189A1 (fr) | 1999-12-28 | 2001-07-05 | Helix Research Institute | Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers |
| AU2001271838A1 (en) * | 2000-07-06 | 2002-01-21 | Bayer Corporation | Human neuropeptide y-like g protein-coupled receptor |
| EP1424392B1 (en) * | 2001-09-03 | 2012-10-24 | Takeda Pharmaceutical Company Limited | RF-peptide ligands of G-protein coupled receptor |
| MXPA04009959A (es) | 2002-04-12 | 2004-12-13 | Schering Corp | Ligandos del receptor acoplado a la proteina g y metodos. |
-
2003
- 2003-04-10 MX MXPA04009959A patent/MXPA04009959A/es active IP Right Grant
- 2003-04-10 WO PCT/US2003/011159 patent/WO2003087134A2/en not_active Ceased
- 2003-04-10 CN CNB038131234A patent/CN1324047C/zh not_active Expired - Fee Related
- 2003-04-10 AU AU2003221878A patent/AU2003221878A1/en not_active Abandoned
- 2003-04-10 JP JP2003584089A patent/JP4594623B2/ja not_active Expired - Fee Related
- 2003-04-10 EP EP03718335A patent/EP1532446B1/en not_active Expired - Lifetime
- 2003-04-10 CA CA002481508A patent/CA2481508A1/en not_active Abandoned
- 2003-04-10 US US10/411,545 patent/US7338772B2/en not_active Expired - Fee Related
- 2003-04-10 AT AT03718335T patent/ATE545866T1/de active
-
2006
- 2006-04-04 JP JP2006103683A patent/JP2006254916A/ja active Pending
-
2008
- 2008-01-07 US US11/970,276 patent/US7807390B2/en not_active Expired - Fee Related
-
2010
- 2010-07-20 JP JP2010163440A patent/JP2010252805A/ja not_active Withdrawn
- 2010-07-20 JP JP2010163439A patent/JP5284313B2/ja not_active Expired - Fee Related
- 2010-10-01 US US12/896,297 patent/US8133980B2/en not_active Expired - Fee Related
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