JP2005528095A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005528095A5 JP2005528095A5 JP2003582284A JP2003582284A JP2005528095A5 JP 2005528095 A5 JP2005528095 A5 JP 2005528095A5 JP 2003582284 A JP2003582284 A JP 2003582284A JP 2003582284 A JP2003582284 A JP 2003582284A JP 2005528095 A5 JP2005528095 A5 JP 2005528095A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- donor
- nucleus
- mammalian
- oocyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 34
- 238000000034 method Methods 0.000 claims 30
- 210000003855 cell nucleus Anatomy 0.000 claims 19
- 210000000287 oocyte Anatomy 0.000 claims 16
- 210000004962 mammalian cell Anatomy 0.000 claims 13
- 210000004940 nucleus Anatomy 0.000 claims 12
- 210000001161 mammalian embryo Anatomy 0.000 claims 11
- 241000894007 species Species 0.000 claims 9
- 241000124008 Mammalia Species 0.000 claims 8
- 230000009261 transgenic effect Effects 0.000 claims 8
- 238000010367 cloning Methods 0.000 claims 7
- 230000004927 fusion Effects 0.000 claims 6
- 230000004913 activation Effects 0.000 claims 5
- 210000003754 fetus Anatomy 0.000 claims 4
- 210000000056 organ Anatomy 0.000 claims 4
- 210000001082 somatic cell Anatomy 0.000 claims 4
- 210000002257 embryonic structure Anatomy 0.000 claims 3
- 210000004291 uterus Anatomy 0.000 claims 3
- GBOGMAARMMDZGR-UHFFFAOYSA-N UNPD149280 Natural products N1C(=O)C23OC(=O)C=CC(O)CCCC(C)CC=CC3C(O)C(=C)C(C)C2C1CC1=CC=CC=C1 GBOGMAARMMDZGR-UHFFFAOYSA-N 0.000 claims 2
- 230000003213 activating effect Effects 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- GBOGMAARMMDZGR-JREHFAHYSA-N cytochalasin B Natural products C[C@H]1CCC[C@@H](O)C=CC(=O)O[C@@]23[C@H](C=CC1)[C@H](O)C(=C)[C@@H](C)[C@@H]2[C@H](Cc4ccccc4)NC3=O GBOGMAARMMDZGR-JREHFAHYSA-N 0.000 claims 2
- GBOGMAARMMDZGR-TYHYBEHESA-N cytochalasin B Chemical compound C([C@H]1[C@@H]2[C@@H](C([C@@H](O)[C@@H]3/C=C/C[C@H](C)CCC[C@@H](O)/C=C/C(=O)O[C@@]23C(=O)N1)=C)C)C1=CC=CC=C1 GBOGMAARMMDZGR-TYHYBEHESA-N 0.000 claims 2
- 210000002950 fibroblast Anatomy 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 230000000284 resting effect Effects 0.000 claims 2
- 241000283690 Bos taurus Species 0.000 claims 1
- 241000283707 Capra Species 0.000 claims 1
- 241000283086 Equidae Species 0.000 claims 1
- 241001494479 Pecora Species 0.000 claims 1
- 241000283984 Rodentia Species 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 210000001612 chondrocyte Anatomy 0.000 claims 1
- 210000003981 ectoderm Anatomy 0.000 claims 1
- 210000001900 endoderm Anatomy 0.000 claims 1
- 230000007159 enucleation Effects 0.000 claims 1
- 210000002615 epidermis Anatomy 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 230000001605 fetal effect Effects 0.000 claims 1
- 210000002216 heart Anatomy 0.000 claims 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 210000002510 keratinocyte Anatomy 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 210000002540 macrophage Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000035800 maturation Effects 0.000 claims 1
- 210000002752 melanocyte Anatomy 0.000 claims 1
- 210000003716 mesoderm Anatomy 0.000 claims 1
- 210000001616 monocyte Anatomy 0.000 claims 1
- 210000000107 myocyte Anatomy 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 230000001850 reproductive effect Effects 0.000 claims 1
- 210000003491 skin Anatomy 0.000 claims 1
- 230000000392 somatic effect Effects 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
- 210000003932 urinary bladder Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36900902P | 2002-04-01 | 2002-04-01 | |
| PCT/US2003/009054 WO2003085105A1 (en) | 2002-04-01 | 2003-03-25 | A method for selecting cell lines to be used for nuclear transfer in mammalian species |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005528095A JP2005528095A (ja) | 2005-09-22 |
| JP2005528095A5 true JP2005528095A5 (enExample) | 2006-05-25 |
Family
ID=28791917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003582284A Pending JP2005528095A (ja) | 2002-04-01 | 2003-03-25 | 哺乳類種における核移植に使用するための細胞株を選択する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20030204860A1 (enExample) |
| EP (1) | EP1490487A4 (enExample) |
| JP (1) | JP2005528095A (enExample) |
| CN (1) | CN1650003A (enExample) |
| AU (1) | AU2003230725A1 (enExample) |
| CA (1) | CA2480802A1 (enExample) |
| NZ (1) | NZ535367A (enExample) |
| WO (1) | WO2003085105A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2874751B2 (ja) | 1986-04-09 | 1999-03-24 | ジェンザイム・コーポレーション | 希望する蛋白質をミルク中へ分泌する遺伝子移植動物 |
| WO2004012499A2 (en) * | 2002-08-01 | 2004-02-12 | Gtc Biotherapeutics, Inc. | Method of selecting cells for somatic cell nuclear transfer |
| PH12013501365A1 (en) | 2010-12-30 | 2013-09-16 | Laboratoire Francais Du Fractionnment Et Des Biotechnologies | Glycols as pathogen inactivating agents |
| BR112015019341A2 (pt) | 2013-02-13 | 2017-08-22 | Lab Francais Du Fractionnement | Anticorpo anti-tnf-alfa, composição que compreende o anticorpo, método para produzir uma população de anticorpos, células epiteliais da glândula mamária, mamífero não humano transgênico, e, composição de anticorpo anti-tnf monoclonal |
| EP2956003A2 (en) | 2013-02-13 | 2015-12-23 | Laboratoire Français du Fractionnement et des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| JP2016532100A (ja) | 2013-07-05 | 2016-10-13 | ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーLaboratoire Francais Du Fractionnement Et Des Biotechnologies | アフィニティークロマトグラフィーマトリックス |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994384A (en) * | 1986-12-31 | 1991-02-19 | W. R. Grace & Co.-Conn. | Multiplying bovine embryos |
| US5496720A (en) * | 1993-02-10 | 1996-03-05 | Susko-Parrish; Joan L. | Parthenogenic oocyte activation |
| GB9517780D0 (en) * | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| GB9517779D0 (en) * | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| IL133786A0 (en) * | 1997-07-03 | 2001-04-30 | Univ Massachusetts | Cloning using donor nuclei from non-serum starved, differentiated cells |
| WO1999045100A1 (en) * | 1998-03-02 | 1999-09-10 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Embryonic or stem-like cell lines produced by cross-species nuclear transplantation |
| GB2365445A (en) * | 1998-10-12 | 2002-02-20 | Geron Bio Med Ltd | Porcine occcytes with improved developmental competence |
| WO2001032854A1 (en) * | 1999-10-29 | 2001-05-10 | Nexia Biotechnologies Inc. | Production of transgenic animals using nuclear transfer and oocytes recovered by lopu |
| KR100417566B1 (ko) * | 1999-11-19 | 2004-02-05 | 한국생명공학연구원 | 체세포 핵치환 복제수정란의 대량생산방법 |
| CA2470195A1 (en) * | 2002-01-11 | 2003-08-07 | Gtc Biotherapeutics, Inc. | Method and system for fusion and activation following nuclear transfer in reconstructed embryos |
-
2003
- 2003-03-25 AU AU2003230725A patent/AU2003230725A1/en not_active Abandoned
- 2003-03-25 US US10/396,890 patent/US20030204860A1/en not_active Abandoned
- 2003-03-25 JP JP2003582284A patent/JP2005528095A/ja active Pending
- 2003-03-25 CA CA002480802A patent/CA2480802A1/en not_active Abandoned
- 2003-03-25 CN CN03809092.9A patent/CN1650003A/zh active Pending
- 2003-03-25 NZ NZ535367A patent/NZ535367A/en not_active IP Right Cessation
- 2003-03-25 EP EP03723815A patent/EP1490487A4/en not_active Withdrawn
- 2003-03-25 WO PCT/US2003/009054 patent/WO2003085105A1/en not_active Ceased
-
2006
- 2006-03-28 US US11/391,148 patent/US20060174359A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1248288B (zh) | 用分化胎儿和成年供体细胞进行的核转移 | |
| US5994619A (en) | Production of chimeric bovine or porcine animals using cultured inner cell mass cells | |
| Westhusin et al. | Cloning to reproduce desired genotypes | |
| Mueller et al. | Chimeric pigs following blastocyst injection of transgenic porcine primordial germ cells | |
| JP2001509362A5 (enExample) | ||
| JP2001509361A (ja) | 分化した無血清飢餓細胞からの供与核を用いるクローニング | |
| AU2211499A (en) | Cloning using donor nuclei from differentiated fetal and adult cells | |
| US7598082B1 (en) | Process of mammalian cell reprogramming through production of a heterokaryon | |
| US20050074439A1 (en) | Cloned ungulate embryos and animals, use of cells, tissues and organs thereof for transplantation therapies including Parkinson's disease | |
| JP5058166B2 (ja) | 細胞核移入 | |
| JP2004500066A (ja) | 異種間核移植により生成する胚あるいは幹様細胞 | |
| JP2005528095A5 (enExample) | ||
| JP2008538898A (ja) | 哺乳動物胚から幹細胞または幹細胞様細胞を作製するための方法 | |
| JP2006508676A (ja) | 追加の核移植のための細胞ドナーとして体細胞核移植胚を利用する方法および系 | |
| JP2003509031A5 (enExample) | ||
| Mrowiec et al. | Technical, biological and molecular aspects of somatic cell nuclear transfer–a review | |
| CA2336437A1 (en) | A process of cell reprogramming through production of a heterokaryon | |
| JP2005528095A (ja) | 哺乳類種における核移植に使用するための細胞株を選択する方法 | |
| JP2008501795A (ja) | ハイブリッド幹細胞の治療的再プログラミングおよび成熟 | |
| JP2003525031A (ja) | 交雑種核移植によって産生された胚細胞または幹様細胞系及びドナー細胞の遺伝子改変または組織培養条件によって胚発達を増強する方法 | |
| US20060021070A1 (en) | Production of chimeric bovine or porcine animals using cultured inner cell mass | |
| Fu | A novel possible approach to the creation of genetically personalized human embryonic stem-like cell lines | |
| JP2009159878A (ja) | 非ヒトes動物の新規作成方法 | |
| EP1282685A2 (en) | Pluripotent cells comprising allogenic nucleus and mitochondria | |
| Revel | Research on animal cloning technologies and their implications in medical ethics: an update |