JP2005527512A - アルツハイマー病の治療および認知増強のための方法 - Google Patents

アルツハイマー病の治療および認知増強のための方法 Download PDF

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JP2005527512A
JP2005527512A JP2003574126A JP2003574126A JP2005527512A JP 2005527512 A JP2005527512 A JP 2005527512A JP 2003574126 A JP2003574126 A JP 2003574126A JP 2003574126 A JP2003574126 A JP 2003574126A JP 2005527512 A JP2005527512 A JP 2005527512A
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bryostatin
disease
pkc
alzheimer
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エッチェベッリガレイ、レネ
アルコン、ダニエル・エル
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ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート
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    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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JP2003574126A 2002-03-07 2003-03-07 アルツハイマー病の治療および認知増強のための方法 Withdrawn JP2005527512A (ja)

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US36208002P 2002-03-07 2002-03-07
US10/167,491 US6825229B2 (en) 2002-03-07 2002-06-13 Methods for Alzheimer's Disease treatment and cognitive enhancement
PCT/US2003/007101 WO2003075850A2 (en) 2002-03-07 2003-03-07 Methods for alzheimer's disease treatment and cognitive enhancement

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JP2005527512A5 JP2005527512A5 (https=) 2006-06-15

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US (4) US6825229B2 (https=)
EP (2) EP1490050B1 (https=)
JP (1) JP2005527512A (https=)
AU (1) AU2003220096A1 (https=)
CA (1) CA2477973A1 (https=)
ES (1) ES2639578T3 (https=)
WO (1) WO2003075850A2 (https=)

Cited By (6)

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WO2008016107A1 (en) * 2006-08-04 2008-02-07 Toyama Chemical Co., Ltd. Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof
JP2010521124A (ja) * 2007-03-09 2010-06-17 クゥアルコム・インコーポレイテッド 不偏トレーニングシーケンスを使用した直交不平衡緩和
JP2013100308A (ja) * 2004-09-10 2013-05-23 Blanchette Rockefeller Neurosciences Inst アルツハイマー病の治療および認知の向上のための方法
JP2016516201A (ja) * 2013-03-15 2016-06-02 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート 神経保護性pkc活性化因子を特定する方法
JP2016101163A (ja) * 2010-02-22 2016-06-02 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート プロテインキナーゼcイプシロン(pkc−イプシロン)タンパク質レベルの、アルツハイマー病に特異的な変化
JP2018521113A (ja) * 2015-05-11 2018-08-02 アルコン、ダニエル・エル. ApoE4対立遺伝子の存在を決定した後のPKC活性化因子を使用した神経変性状態の治療

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US20080004332A1 (en) * 2002-03-07 2008-01-03 Alkon Daniel L Methods for alzheimer's disease treatment and cognitive enhancement
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US20070037871A1 (en) * 2002-07-02 2007-02-15 Blanchette Rockefeller Neurosciences Instiute Pkc activation as a means for enhancing sappalpha secretion and improving cognition using bryostatin type compounds
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TW201206425A (en) 2004-05-18 2012-02-16 Brni Neurosciences Inst Treatment of depressive disorders
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US20070054890A1 (en) * 2005-07-29 2007-03-08 Alkon Daniel L Protein synthesis required for long-term memory is induced by PKC activation on days preceding associative learning
WO2007044094A1 (en) * 2005-10-11 2007-04-19 Blanchette Rockefeller Neurosciences Institute Alzheimer's disease-specific alterations of the erk1/erk2 phosphorylation ratio as alzheimer's disease-specific molecular biomarkers (adsmb)
CN103961347A (zh) * 2006-07-28 2014-08-06 布朗歇特洛克菲勒神经科学研究所 刺激细胞生长、突触重塑和巩固长期记忆的方法
US20170319541A9 (en) * 2006-07-28 2017-11-09 Blanchette Rockefeller Neuroscience Institute Methods of stimulating cellular growth, synaptic remodeling and consolidation of long-term memory
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US20110023152A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genome editing of cognition related genes in animals
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JP6422778B2 (ja) 2011-11-13 2018-11-14 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート Pkcアクチベーターおよびその組合せ
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