JP2005525173A - 電場応答性ポリマを用いた人工括約筋及び人工筋肉パッチ - Google Patents
電場応答性ポリマを用いた人工括約筋及び人工筋肉パッチ Download PDFInfo
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- JP2005525173A JP2005525173A JP2004502890A JP2004502890A JP2005525173A JP 2005525173 A JP2005525173 A JP 2005525173A JP 2004502890 A JP2004502890 A JP 2004502890A JP 2004502890 A JP2004502890 A JP 2004502890A JP 2005525173 A JP2005525173 A JP 2005525173A
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- artificial
- artificial sphincter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0004—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse
- A61F2/0031—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse for constricting the lumen; Support slings for the urethra
- A61F2/0036—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse for constricting the lumen; Support slings for the urethra implantable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
- A61B2017/00871—Material properties shape memory effect polymeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2002/0894—Muscles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0058—Catheters; Hollow probes characterised by structural features having an electroactive polymer material, e.g. for steering purposes, for control of flexibility, for locking, for opening or closing
Abstract
Description
Claims (44)
- 生体内腔の周囲に配設されるよう構成され、1つ以上の電場応答性ポリマアクチュエータを有するカフと、
上記1つ以上の電場応答性ポリマアクチュエータを電気的に制御して、上記カフを拡張又は収縮させる制御ユニットと
を備えることを特徴とする人工括約筋。 - 上記1つ以上の電場応答性ポリマアクチュエータは、(a)1つ以上のアクティブ部材と、(b)対電極と、(c)上記アクティブ部材及び上記対電極の間に配置された電解質とを含むことを特徴とする請求項1記載の人工括約筋。
- 上記1つ以上のアクティブ部材は、少なくとも1つの基板層上に設けられていることを特徴とする請求項2記載の人工括約筋。
- 少なくとも1つのバリア層を更に備えることを特徴とする請求項3記載の人工括約筋。
- 外側のメッシュ層を更に備えることを特徴とする請求項4記載の人工括約筋。
- 上記1つ以上のアクティブ部材は、非線形の形状に構成されていることを特徴とする請求項3記載の人工括約筋。
- 上記基板層は、少なくとも2つ設けられていることを特徴とする請求項3記載の人工括約筋。
- 上記基板層は、絶縁層であることを特徴とする請求項3記載の人工括約筋。
- 上記基板層上には、上記1つ以上のアクティブ部材と上記電源との間を電気的に接続する導電配線が配設されていることを特徴とする請求項8記載の人工括約筋。
- 上記基板層は、導電層であることを特徴とする請求項3記載の人工括約筋。
- 上記カフの両端には、上記生体内腔の周囲に該カフを固定するためのファスナが設けられていることを特徴とする請求項1記載の人工括約筋。
- 上記制御ユニットは、電源と、スイッチとを備えることを特徴とする請求項1記載の人工括約筋。
- 上記カフは、尿道の周囲に取り付けられることを特徴とする請求項1記載の人工括約筋。
- 上記カフは、肛門管の周囲に取り付けられることを特徴とする請求項1記載の人工括約筋。
- 上記カフは、下部食道の周囲に取り付けられることを特徴とする請求項1記載の人工括約筋。
- 食物又は飲料が上記下部食道に流入したことを検出するためのセンサを更に備えることを特徴とする請求項15記載の人工括約筋。
- 胃が内容物を吐き戻そうとしていることを検出するためのセンサを更に備えることを特徴とする請求項15記載の人工括約筋。
- 上記電場応答性ポリマアクチュエータは、ポリアニリン、ポリピロール及びポリアセチレンからなるグループから選択される電場応答性ポリマを含むことを特徴とする請求項1記載の人工括約筋。
- 上記電場応答性ポリマは、ポリピロールであることを特徴とする請求項18記載の人工括約筋。
- 上記カフは、該カフを拡張状態又は収縮状態に戻す復元力を有することを特徴とする請求項1記載の人工括約筋。
- 上記復元力を提供する少なくとも1つの弾性の構造的要素を更に備えることを特徴とする請求項20記載の人工括約筋。
- 上記少なくとも1つの構造的要素は、断面直径が減少すると長さが増加する弾性を有する環状の管であることを特徴とする請求項21記載の人工括約筋。
- 上記電場応答性ポリマアクチュエータの収縮の程度を検知するセンサを更に備えることを特徴とする請求項1記載の人工括約筋。
- 上記センサは、複数の歪みゲージを含むことを特徴とする請求項23記載の人工括約筋。
- 請求項14記載の人工括約筋を患者に移植するステップを有することを特徴とする便失禁の治療方法。
- 請求項13記載の人工括約筋を患者に移植するステップを有することを特徴とする尿失禁の治療方法。
- 請求項15記載の人工括約筋を患者に移植するステップを有することを特徴とする胃食道逆流性疾患の治療方法。
- 上記制御ユニットは、電源とコンピュータとを備えることを特徴とする請求項1記載の人工括約筋。
- 1つ以上の電場応答性ポリマアクチュエータと、
上記人工筋肉パッチを拡張又は収縮させるように上記1つ以上の電場応答性ポリマアクチュエータを電気的に制御する制御ユニットとを備え、
患者の心臓に接するように移植されることを特徴とする人工筋肉パッチ。 - 上記1つ以上の電場応答性ポリマアクチュエータは、(a)1つ以上のアクティブ部材と、(b)対電極と、(c)上記アクティブ部材及び上記対電極の間に配置された電解質とを含むことを特徴とする請求項29記載の人工筋肉パッチ。
- 上記1つ以上のアクティブ部材は、少なくとも1つの基板層上に設けられていることを特徴とする請求項30記載の人工筋肉パッチ。
- 少なくとも1つのバリア層を更に備えることを特徴とする請求項31記載の人工筋肉パッチ。
- 外側のメッシュ層を更に備えることを特徴とする請求項32記載の人工筋肉パッチ。
- 上記1つ以上のアクティブ部材は、非線形の形状に構成されていることを特徴とする請求項31記載の人工筋肉パッチ。
- 上記基板層は、少なくとも2つ設けられていることを特徴とする請求項31記載の人工筋肉パッチ。
- 上記基板層は、絶縁層であることを特徴とする請求項31記載の人工筋肉パッチ。
- 上記基板層上には、上記1つ以上のアクティブ部材と上記電源との間を電気的に接続する導電配線が配設されていることを特徴とする請求項36記載の人工筋肉パッチ。
- 上記基板層は、導電層であることを特徴とする請求項31記載の人工筋肉パッチ。
- 上記制御ユニットは、電源と、スイッチとを備えることを特徴とする請求項29記載の人工筋肉パッチ。
- 上記制御ユニットは、電源とコンピュータとを備えることを特徴とする請求項29記載の人工筋肉パッチ。
- 患者の鼓動を検出するセンサを更に備え、
上記制御ユニットは、上記鼓動に応じて上記電場応答性ポリマアクチュエータの収縮及び拡張をペーシングすることを特徴とする請求項29記載の人工筋肉パッチ。 - 上記制御ユニットは、上記電場応答性ポリマアクチュエータの収縮及び拡張に加えて、心臓をペーシングすることを特徴とする請求項29記載の人工筋肉パッチ。
- 上記電場応答性ポリマは、ポリピロールであることを特徴とする請求項29記載の人工筋肉パッチ。
- 請求項29記載の人工筋肉パッチを患者の心臓に接するように移植するステップを有することを特徴とする鬱血性心不全の治療方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/142,861 US6749556B2 (en) | 2002-05-10 | 2002-05-10 | Electroactive polymer based artificial sphincters and artificial muscle patches |
PCT/US2003/014624 WO2003094800A2 (en) | 2002-05-10 | 2003-05-09 | Electroactive polymer based artificial sphincters and artificial muscle patches |
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JP2005525173A true JP2005525173A (ja) | 2005-08-25 |
JP4467426B2 JP4467426B2 (ja) | 2010-05-26 |
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US (5) | US6749556B2 (ja) |
EP (1) | EP1503703A2 (ja) |
JP (1) | JP4467426B2 (ja) |
AU (1) | AU2003228965A1 (ja) |
CA (1) | CA2490772A1 (ja) |
WO (1) | WO2003094800A2 (ja) |
Cited By (7)
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JP2009527287A (ja) * | 2006-02-16 | 2009-07-30 | パヴァド メディカル インコーポレイテッド | 自動充電気道インプラントならびにこれを作製および使用する方法 |
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JP2007125246A (ja) * | 2005-11-04 | 2007-05-24 | Terumo Corp | 血圧測定装置及びそれに用いるカフ |
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KR101322887B1 (ko) * | 2006-03-15 | 2013-10-29 | 코어 와이어리스 라이센싱 에스.에이.알.엘. | 모바일 카메라를 위한 구경 구조 |
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Also Published As
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US20050004425A1 (en) | 2005-01-06 |
JP4467426B2 (ja) | 2010-05-26 |
US20030212306A1 (en) | 2003-11-13 |
WO2003094800A3 (en) | 2004-04-01 |
US6921360B2 (en) | 2005-07-26 |
US7566297B2 (en) | 2009-07-28 |
WO2003094800A2 (en) | 2003-11-20 |
US20070043256A1 (en) | 2007-02-22 |
AU2003228965A1 (en) | 2003-11-11 |
CA2490772A1 (en) | 2003-11-20 |
US6749556B2 (en) | 2004-06-15 |
US20090259315A1 (en) | 2009-10-15 |
US7128707B2 (en) | 2006-10-31 |
US8100819B2 (en) | 2012-01-24 |
EP1503703A2 (en) | 2005-02-09 |
US20050256367A1 (en) | 2005-11-17 |
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