JP2005522210A5 - - Google Patents
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- Publication number
- JP2005522210A5 JP2005522210A5 JP2003583334A JP2003583334A JP2005522210A5 JP 2005522210 A5 JP2005522210 A5 JP 2005522210A5 JP 2003583334 A JP2003583334 A JP 2003583334A JP 2003583334 A JP2003583334 A JP 2003583334A JP 2005522210 A5 JP2005522210 A5 JP 2005522210A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- fusion protein
- biological sample
- antigen
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 229920001184 polypeptide Polymers 0.000 claims 17
- 102000004196 processed proteins & peptides Human genes 0.000 claims 17
- 108090000765 processed proteins & peptides Proteins 0.000 claims 17
- 108020001507 fusion proteins Proteins 0.000 claims 9
- 102000037865 fusion proteins Human genes 0.000 claims 9
- 102000040430 polynucleotide Human genes 0.000 claims 8
- 108091033319 polynucleotide Proteins 0.000 claims 8
- 239000002157 polynucleotide Substances 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 108091007433 antigens Proteins 0.000 claims 6
- 239000012472 biological sample Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 230000004927 fusion Effects 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 208000009889 Herpes Simplex Diseases 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 238000009007 Diagnostic Kit Methods 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 229960001438 immunostimulant agent Drugs 0.000 claims 2
- 239000003022 immunostimulating agent Substances 0.000 claims 2
- 230000003308 immunostimulating effect Effects 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 125000006853 reporter group Chemical group 0.000 claims 2
- 210000003296 saliva Anatomy 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 210000002700 urine Anatomy 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004856 Lectins Human genes 0.000 claims 1
- 108090001090 Lectins Proteins 0.000 claims 1
- 101150047390 MCP gene Proteins 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 claims 1
- 101710120037 Toxin CcdB Proteins 0.000 claims 1
- 101150109748 UL19 gene Proteins 0.000 claims 1
- 125000004103 aminoalkyl group Chemical group 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 150000008271 glucosaminides Chemical class 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 239000002523 lectin Substances 0.000 claims 1
- 229940035032 monophosphoryl lipid a Drugs 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 229930182490 saponin Natural products 0.000 claims 1
- 150000007949 saponins Chemical class 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/121,988 US20030068327A1 (en) | 2000-06-29 | 2002-04-11 | Compositions and methods for the diagnosis and threatment of herpes simplex virus infection |
| US10/200,562 US20030165819A1 (en) | 2000-06-29 | 2002-07-19 | Compositions and methods for the diagnosis and treatment of herpes simplex virus infection |
| US10/237,551 US6821519B2 (en) | 2000-06-29 | 2002-09-06 | Compositions and methods for the diagnosis and treatment of herpes simplex virus infection |
| PCT/US2003/011231 WO2003086308A2 (en) | 2002-04-11 | 2003-04-09 | Compositions and methods for the diagnosis and treatment of herpes simplex virus infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005522210A JP2005522210A (ja) | 2005-07-28 |
| JP2005522210A5 true JP2005522210A5 (https=) | 2006-06-29 |
Family
ID=29255203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003583334A Withdrawn JP2005522210A (ja) | 2002-04-11 | 2003-04-09 | 単純ヘルペスウイルス感染の診断および処置に対する組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6821519B2 (https=) |
| EP (1) | EP1492563A4 (https=) |
| JP (1) | JP2005522210A (https=) |
| AU (1) | AU2003221897A1 (https=) |
| CA (1) | CA2481087A1 (https=) |
| WO (1) | WO2003086308A2 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2272859T3 (en) * | 1998-08-07 | 2015-01-19 | Univ Washington | Immunological herpes simplex virus antigens and methods for their use |
| US6507042B1 (en) * | 1998-12-25 | 2003-01-14 | Fujitsu Limited | Semiconductor device and method of manufacturing the same |
| US20040170642A1 (en) * | 2000-08-17 | 2004-09-02 | Jorg Fritiz | Vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide of a derivative thereof |
| JP4519461B2 (ja) * | 2001-07-31 | 2010-08-04 | ユニヴァーシティ オブ ワシントン | 免疫学的に重要な単純ヘルペスウイルス抗原およびそれを用いる方法 |
| DK1523582T3 (da) * | 2002-07-18 | 2009-03-02 | Univ Washington | Hurtig, effektiv rensning af HSV-specifikke T-lymfocytter samt HSV-antigener identificeret derved |
| US7267940B2 (en) * | 2003-03-04 | 2007-09-11 | Bio-Rad Laboratories, Inc. | HSV-2 type-specific immunoassays using glycoprotein G2 peptides |
| US20040203084A1 (en) * | 2003-04-10 | 2004-10-14 | Doug Levinson | Profiling conformational variants, antibody compositions and methods of using the same |
| CA2523016C (en) * | 2003-04-25 | 2018-05-15 | Becton, Dickinson And Company | Detection of herpes simplex virus types 1 and 2 by nucleic acid amplification |
| JP2007505147A (ja) * | 2003-09-12 | 2007-03-08 | アンティジェニクス インコーポレーテッド | 単純ヘルペスウイルス感染の治療および予防用ワクチン |
| US7638318B2 (en) * | 2003-09-26 | 2009-12-29 | Norvartis Ag | Seneca Valley virus based compositions and methods for treating disease |
| CN101023187A (zh) * | 2004-03-05 | 2007-08-22 | 伯乐实验室有限公司 | 使用糖蛋白g2肽的hsv－2型特异性免疫测试 |
| EP1913141A2 (en) * | 2005-06-03 | 2008-04-23 | The CBR Institute for Biomedical Research, Inc. | Sirna microbicides for preventing and treating viral diseases |
| US7763460B2 (en) | 2005-06-24 | 2010-07-27 | Focus Diagnostics, Inc. | Methods and compositions for detecting herpes simplex virus type 2 |
| EP2521786B1 (en) | 2006-07-20 | 2015-06-24 | Vical Incorporated | Compositions for vaccinating against hsv-2 |
| US8865185B2 (en) | 2006-09-08 | 2014-10-21 | The Trustees Of The University Of Pennsylvania | Methods of use for HSV-1 and HSV-2 vaccines |
| JP5639361B2 (ja) | 2006-09-08 | 2014-12-10 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Ｈｓｖ−１及びｈｓｖ−２ワクチン並びにその使用方法 |
| WO2008085486A1 (en) | 2006-12-28 | 2008-07-17 | The Trustees Of The University Of Pennsylvania | Herpes simplex virus combined subunit vaccines and methods of use thereof |
| US20130028925A1 (en) * | 2006-12-28 | 2013-01-31 | Harvey Friedman | Herpes simplex virus combined subunit vaccines and methods of use thereof |
| US10478490B2 (en) | 2006-12-28 | 2019-11-19 | The Trustees Of The University Of Pennsylvania | Herpes simplex virus combined subunit vaccines and methods of use thereof |
| US8460674B2 (en) | 2009-02-07 | 2013-06-11 | University Of Washington | HSV-1 epitopes and methods for using same |
| WO2010115172A2 (en) | 2009-04-03 | 2010-10-07 | University Of Washington | Antigenic peptide of hsv-2 and methods for using same |
| EP3756684A1 (en) * | 2009-05-22 | 2020-12-30 | Genocea Biosciences, Inc. | Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
| EP2643014A4 (en) * | 2010-11-24 | 2015-11-11 | Genocea Biosciences Inc | HERPES SIMPLEX TYPE 2 VIRUS VACCINES: COMPOSITIONS AND METHODS FOR STIMULATING AN IMMUNE RESPONSE |
| US9629906B2 (en) | 2011-10-05 | 2017-04-25 | Genvec, Inc. | Affenadenovirus (gorilla) or adenoviral vectors and methods of use |
| EP2764012B1 (en) | 2011-10-05 | 2022-02-23 | GenVec, Inc. | Adenoviral vectors and methods of use |
| WO2013052832A2 (en) | 2011-10-05 | 2013-04-11 | Genvec, Inc. | Adenoviral vectors and methods of use |
| EP2782597B1 (en) * | 2011-11-23 | 2022-04-13 | Genocea Biosciences, Inc. | Nucleic acid vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
| KR102136433B1 (ko) | 2012-05-16 | 2020-07-22 | 이뮨 디자인 코포레이션 | Hsv-2 백신 |
| EP2855511B1 (en) | 2012-05-29 | 2019-07-24 | GenVec, Inc. | Herpes simplex virus vaccine |
| JP2019537555A (ja) | 2016-09-28 | 2019-12-26 | ジェノセア バイオサイエンシーズ， インコーポレイテッド | ヘルペスを処置するための方法および組成物 |
| KR101962683B1 (ko) * | 2016-09-28 | 2019-03-27 | 주식회사 에스엘백시젠 | Hsv-2 감염 예방 및 치료용 dna 백신 |
| WO2018186755A1 (en) * | 2017-04-04 | 2018-10-11 | Beagley Kenneth | Novel vaccine for the prevention or treatment of an infection caused by a herpes virus. |
| CN109701008B (zh) * | 2019-02-18 | 2022-06-21 | 山东兴瑞生物科技有限公司 | 针对单纯疱疹病毒的治疗性dc复合疫苗及其制备方法 |
| EP3999093A4 (en) * | 2019-07-19 | 2023-11-22 | Merck Sharp & Dohme LLC | ANTIGENIC E GLYCOPROTEIN POLYPEPTIDES, COMPOSITIONS AND METHODS OF USE THEREOF |
| KR20220035457A (ko) * | 2019-07-21 | 2022-03-22 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 치료 바이러스 백신 |
| WO2025153100A1 (en) * | 2024-01-19 | 2025-07-24 | Sichuan Clover Biopharmaceuticals, Inc. | Herpes simplex virus recombinant antigen and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW232710B (https=) | 1991-09-13 | 1994-10-21 | American Cyanamid Co | |
| ATE157882T1 (de) * | 1993-03-23 | 1997-09-15 | Smithkline Beecham Biolog | 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen |
| US6197497B1 (en) * | 1995-04-21 | 2001-03-06 | University Of New Mexico | Immunoassay for herpes simplex virus |
| AT404838B (de) | 1995-11-24 | 1999-03-25 | Immuno Ag | Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen |
| CA2270282A1 (en) * | 1996-11-04 | 1998-05-14 | Smithkline Beecham Corporation | Novel coding sequences from herpes simplex virus type-2 |
| US6022847A (en) * | 1997-03-19 | 2000-02-08 | Zymogenetics, Inc. | Secreted salivary zsig32 polypeptides |
| CA2291010A1 (en) | 1997-06-02 | 1998-12-10 | Chiron Corporation | Herpes simplex virus vp22 vaccines and methods of use |
| WO1999064633A1 (en) | 1998-06-10 | 1999-12-16 | Smithkline Beecham Corporation | Herpes simplex virus origin binding protein n-terminal truncation (obp-nt) |
| DK2272859T3 (en) | 1998-08-07 | 2015-01-19 | Univ Washington | Immunological herpes simplex virus antigens and methods for their use |
| HK1044799A1 (zh) | 1999-09-30 | 2002-11-01 | University Of Washington | 免疫学上重要的单纯疱疹病毒抗原 |
-
2002
- 2002-09-06 US US10/237,551 patent/US6821519B2/en not_active Expired - Fee Related
-
2003
- 2003-04-09 EP EP03718356A patent/EP1492563A4/en not_active Withdrawn
- 2003-04-09 CA CA002481087A patent/CA2481087A1/en not_active Abandoned
- 2003-04-09 JP JP2003583334A patent/JP2005522210A/ja not_active Withdrawn
- 2003-04-09 AU AU2003221897A patent/AU2003221897A1/en not_active Abandoned
- 2003-04-09 WO PCT/US2003/011231 patent/WO2003086308A2/en not_active Ceased
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