JP2005521671A5 - - Google Patents
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- Publication number
- JP2005521671A5 JP2005521671A5 JP2003564046A JP2003564046A JP2005521671A5 JP 2005521671 A5 JP2005521671 A5 JP 2005521671A5 JP 2003564046 A JP2003564046 A JP 2003564046A JP 2003564046 A JP2003564046 A JP 2003564046A JP 2005521671 A5 JP2005521671 A5 JP 2005521671A5
- Authority
- JP
- Japan
- Prior art keywords
- disorder
- diabetes
- compound according
- triaza
- fluorene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0202015.4A GB0202015D0 (en) | 2002-01-29 | 2002-01-29 | Piperazine Derivatives |
| PCT/EP2003/000459 WO2003064423A1 (en) | 2002-01-29 | 2003-01-17 | Aza-arylpiperazines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005521671A JP2005521671A (ja) | 2005-07-21 |
| JP2005521671A5 true JP2005521671A5 (https=) | 2005-12-22 |
| JP4213042B2 JP4213042B2 (ja) | 2009-01-21 |
Family
ID=9929954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003564046A Expired - Fee Related JP4213042B2 (ja) | 2002-01-29 | 2003-01-17 | アザ−アリールピペラジン |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US7098337B2 (https=) |
| EP (1) | EP1472255B1 (https=) |
| JP (1) | JP4213042B2 (https=) |
| KR (1) | KR100644004B1 (https=) |
| CN (1) | CN1290847C (https=) |
| AR (1) | AR038237A1 (https=) |
| AT (1) | ATE318817T1 (https=) |
| AU (1) | AU2003205622B2 (https=) |
| BR (1) | BR0307291A (https=) |
| CA (1) | CA2472954C (https=) |
| DE (1) | DE60303791T2 (https=) |
| DK (1) | DK1472255T3 (https=) |
| EA (1) | EA200400881A1 (https=) |
| EC (1) | ECSP045208A (https=) |
| ES (1) | ES2259757T3 (https=) |
| GB (1) | GB0202015D0 (https=) |
| GT (1) | GT200300015A (https=) |
| HR (1) | HRP20040653A2 (https=) |
| IL (1) | IL162727A0 (https=) |
| MA (1) | MA27097A1 (https=) |
| MX (1) | MXPA04007147A (https=) |
| NO (1) | NO20043547L (https=) |
| PA (1) | PA8564001A1 (https=) |
| PE (1) | PE20030847A1 (https=) |
| PL (1) | PL371922A1 (https=) |
| PT (1) | PT1472255E (https=) |
| RS (1) | RS65704A (https=) |
| SI (1) | SI1472255T1 (https=) |
| TN (1) | TNSN04136A1 (https=) |
| TW (1) | TW200307683A (https=) |
| UY (1) | UY27627A1 (https=) |
| WO (1) | WO2003064423A1 (https=) |
| ZA (1) | ZA200405458B (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05012547A (es) * | 2003-05-21 | 2006-05-25 | Prosidion Ltd | Inhibidores de amida de acido pirrolopiridina-2-carboxilico de fosforilasa de glucogeno. |
| US7405210B2 (en) | 2003-05-21 | 2008-07-29 | Osi Pharmaceuticals, Inc. | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase |
| GB0314967D0 (en) * | 2003-06-26 | 2003-07-30 | Hoffmann La Roche | Piperazine derivatives |
| TW200528102A (en) * | 2003-10-24 | 2005-09-01 | Solvay Pharm Gmbh | Novel medical combination treatment of obesity involving 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity |
| WO2005039579A1 (en) * | 2003-10-24 | 2005-05-06 | Solvay Pharmaceuticals Gmbh | Combination treatment of obesity involving selective cb1-antagonists and lipase inhibitors |
| EP2248524A3 (en) | 2004-08-25 | 2011-03-09 | Takeda Pharmaceutical Company Limited | Preventives/remedies for stress urinary incontinence and method of screening the same |
| AU2005298692A1 (en) | 2004-10-25 | 2006-05-04 | Solvay Pharmaceuticals Gmbh | Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of diabetes mellitus type I, obesity and related conditions |
| ATE514698T1 (de) | 2005-05-03 | 2011-07-15 | Hoffmann La Roche | Tetracyclische azapyrazinoindoline als 5-ht2- liganden |
| WO2006125179A1 (en) * | 2005-05-19 | 2006-11-23 | Xenon Pharmaceuticals Inc. | Tricyclic compounds and their uses as therapeutic agents |
| ES2351940T3 (es) * | 2005-11-18 | 2011-02-14 | F. Hoffmann-La Roche Ag | Derivados de azaindol-2-carboxamida. |
| JP2009518351A (ja) | 2005-12-09 | 2009-05-07 | エフ．ホフマン−ラ ロシュ アーゲー | 肥満症の処置に有用な三環性アミド誘導体 |
| BRPI0619985A2 (pt) | 2005-12-16 | 2011-10-25 | Hoffmann La Roche | compostos, processo para a sua manufatura, composições farmacêuticas, métodos para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, de obesidade e de diabetes do tipo ii em um ser humano ou animal e usos dos compostos |
| EP2742936A1 (en) | 2006-05-16 | 2014-06-18 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound and use thereof |
| JP2010500300A (ja) | 2006-08-08 | 2010-01-07 | サノフィ−アベンティス | アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用 |
| EP2789338A3 (en) | 2007-11-15 | 2015-01-14 | Takeda Pharmaceutical Company Limited | Condensed pyridine derivate and use thereof |
| WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| MX2012001729A (es) | 2009-08-26 | 2012-06-13 | Sanofi Sa | Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo. |
| JPWO2011071136A1 (ja) | 2009-12-11 | 2013-04-22 | アステラス製薬株式会社 | 線維筋痛症治療剤 |
| FR2960876B1 (fr) * | 2010-06-03 | 2012-07-27 | Sanofi Aventis | Derives de 3,4-dihydropyrrolo[1,2-a]pyrazine-2,8(1h)-dicarboxamide leur preparation et leur application en therapeutique. |
| EP2683702B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683701B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| EP2683698B1 (de) | 2011-03-08 | 2017-10-04 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8895547B2 (en) | 2011-03-08 | 2014-11-25 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| EP2841417A1 (en) * | 2012-04-26 | 2015-03-04 | Francis Xavier Tavares | Synthesis of lactams |
| CN104540829B (zh) * | 2012-08-06 | 2017-04-26 | 霍夫曼-拉罗奇有限公司 | 哌嗪并[1,2‑a]吲哚‑1‑酮和[1,4]二氮杂*并[1,2‑a]吲哚‑1‑酮 |
| WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
| WO2018035477A1 (en) * | 2016-08-19 | 2018-02-22 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
| EP3733204A4 (en) | 2017-12-27 | 2021-09-15 | Takeda Pharmaceutical Company Limited | THERAPEUTIC AGENT FOR URINARY INCONTINENCE OF STRESS AND FECAL INCONTINENCE |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1247547A (en) * | 1983-06-22 | 1988-12-28 | Paul Hadvary | Leucine derivatives |
| CA1328881C (en) | 1984-12-21 | 1994-04-26 | Pierre Barbier | Process for the manufacture of oxetanones |
| CA1270837A (en) * | 1984-12-21 | 1990-06-26 | Hoffmann-La Roche Limited | Oxetanones |
| CA2035972C (en) | 1990-02-23 | 2006-07-11 | Martin Karpf | Process for the preparation of oxetanones |
| US5274143A (en) | 1991-07-23 | 1993-12-28 | Hoffmann-La Roche Inc. | Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione |
| US6004996A (en) * | 1997-02-05 | 1999-12-21 | Hoffman-La Roche Inc. | Tetrahydrolipstatin containing compositions |
| US6267952B1 (en) | 1998-01-09 | 2001-07-31 | Geltex Pharmaceuticals, Inc. | Lipase inhibiting polymers |
| PT1105123E (pt) | 1998-08-14 | 2004-08-31 | Hoffmann La Roche | Composicoes farmaceuticas contendo inibidores da lipase e quitosano |
| TR200100471T2 (tr) | 1998-08-14 | 2001-07-23 | F.Hoffmann-La Roche Ag | Lipaz inhibitörleri içeren farmasötik bileşimler |
| GB9902047D0 (en) * | 1999-01-29 | 1999-03-17 | Cerebrus Ltd | Chemical compounds XI |
| FR2799757B1 (fr) * | 1999-10-15 | 2001-12-14 | Adir | Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2002
- 2002-01-29 GB GBGB0202015.4A patent/GB0202015D0/en not_active Ceased
-
2003
- 2003-01-17 PL PL03371922A patent/PL371922A1/xx not_active Application Discontinuation
- 2003-01-17 CN CNB03802943XA patent/CN1290847C/zh not_active Expired - Fee Related
- 2003-01-17 AT AT03702462T patent/ATE318817T1/de active
- 2003-01-17 HR HR20040653A patent/HRP20040653A2/hr not_active Application Discontinuation
- 2003-01-17 PT PT03702462T patent/PT1472255E/pt unknown
- 2003-01-17 IL IL16272703A patent/IL162727A0/xx unknown
- 2003-01-17 BR BR0307291-6A patent/BR0307291A/pt not_active IP Right Cessation
- 2003-01-17 MX MXPA04007147A patent/MXPA04007147A/es unknown
- 2003-01-17 KR KR1020047011619A patent/KR100644004B1/ko not_active Expired - Fee Related
- 2003-01-17 EP EP03702462A patent/EP1472255B1/en not_active Expired - Lifetime
- 2003-01-17 ES ES03702462T patent/ES2259757T3/es not_active Expired - Lifetime
- 2003-01-17 DE DE60303791T patent/DE60303791T2/de not_active Expired - Lifetime
- 2003-01-17 JP JP2003564046A patent/JP4213042B2/ja not_active Expired - Fee Related
- 2003-01-17 WO PCT/EP2003/000459 patent/WO2003064423A1/en not_active Ceased
- 2003-01-17 AU AU2003205622A patent/AU2003205622B2/en not_active Ceased
- 2003-01-17 CA CA002472954A patent/CA2472954C/en not_active Expired - Fee Related
- 2003-01-17 DK DK03702462T patent/DK1472255T3/da active
- 2003-01-17 SI SI200330231T patent/SI1472255T1/sl unknown
- 2003-01-17 RS YU65704A patent/RS65704A/sr unknown
- 2003-01-17 EA EA200400881A patent/EA200400881A1/ru unknown
- 2003-01-24 PE PE2003000073A patent/PE20030847A1/es not_active Application Discontinuation
- 2003-01-24 US US10/350,616 patent/US7098337B2/en not_active Expired - Fee Related
- 2003-01-27 GT GT200300015A patent/GT200300015A/es unknown
- 2003-01-27 AR ARP030100229A patent/AR038237A1/es unknown
- 2003-01-28 PA PA20038564001A patent/PA8564001A1/es unknown
- 2003-01-28 TW TW092101825A patent/TW200307683A/zh unknown
- 2003-01-28 UY UY27627A patent/UY27627A1/es not_active Application Discontinuation
-
2004
- 2004-06-30 MA MA27756A patent/MA27097A1/fr unknown
- 2004-07-08 ZA ZA200405458A patent/ZA200405458B/en unknown
- 2004-07-22 TN TNP2004000136A patent/TNSN04136A1/en unknown
- 2004-07-27 EC EC2004005208A patent/ECSP045208A/es unknown
- 2004-08-25 NO NO20043547A patent/NO20043547L/no unknown