JP2005521401A - ポリペプチド産生を増加させる方法 - Google Patents

ポリペプチド産生を増加させる方法 Download PDF

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Publication number
JP2005521401A
JP2005521401A JP2003580502A JP2003580502A JP2005521401A JP 2005521401 A JP2005521401 A JP 2005521401A JP 2003580502 A JP2003580502 A JP 2003580502A JP 2003580502 A JP2003580502 A JP 2003580502A JP 2005521401 A JP2005521401 A JP 2005521401A
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polypeptide
cell line
temperature
mmol
medium
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Pending
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Japanese (ja)
Inventor
バンネス，カーク・ピー
トレンタランジェ，マイケル・ティー
デル，ブラッドレー・ディー
マックグリュー，ジェフリー・ティー
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Immunex Corp
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Immunex Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28678222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2005521401(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of JP2005521401A publication Critical patent/JP2005521401A/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2003580502A 2002-03-27 2003-03-27 ポリペプチド産生を増加させる方法 Pending JP2005521401A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36824802P 2002-03-27 2002-03-27
US36824602P 2002-03-27 2002-03-27
PCT/US2003/009266 WO2003083066A2 (en) 2002-03-27 2003-03-27 Methods for increasing polypeptide production

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2008024395A Division JP4414466B2 (ja) 2002-03-27 2008-02-04 ポリペプチド産生を増加させる方法
JP2008301520A Division JP4414472B2 (ja) 2002-03-27 2008-11-26 ポリペプチド産生を増加させる方法

Publications (1)

Publication Number Publication Date
JP2005521401A true JP2005521401A (ja) 2005-07-21

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ID=28678222

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2003580502A Pending JP2005521401A (ja) 2002-03-27 2003-03-27 ポリペプチド産生を増加させる方法
JP2008024395A Expired - Lifetime JP4414466B2 (ja) 2002-03-27 2008-02-04 ポリペプチド産生を増加させる方法
JP2008301520A Expired - Lifetime JP4414472B2 (ja) 2002-03-27 2008-11-26 ポリペプチド産生を増加させる方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2008024395A Expired - Lifetime JP4414466B2 (ja) 2002-03-27 2008-02-04 ポリペプチド産生を増加させる方法
JP2008301520A Expired - Lifetime JP4414472B2 (ja) 2002-03-27 2008-11-26 ポリペプチド産生を増加させる方法

Country Status (9)

Country Link
US (2) US6872549B2 (enExample)
EP (1) EP1497444B1 (enExample)
JP (3) JP2005521401A (enExample)
AU (1) AU2003220529B2 (enExample)
CA (1) CA2480121C (enExample)
ES (1) ES2557741T3 (enExample)
MX (1) MXPA04009381A (enExample)
PL (1) PL376821A1 (enExample)
WO (1) WO2003083066A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007049567A1 (ja) * 2005-10-24 2007-05-03 Kyowa Hakko Kogyo Co., Ltd. 物質の製造方法
JP6001456B2 (ja) * 2010-12-28 2016-10-05 中外製薬株式会社 動物細胞の培養方法
JP2021500069A (ja) * 2017-10-23 2021-01-07 プロゲン・シーオー., エルティーディー.Progen Co., Ltd. 改変ｅｇｆタンパク質、その製造方法及びその使用

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007049567A1 (ja) * 2005-10-24 2007-05-03 Kyowa Hakko Kogyo Co., Ltd. 物質の製造方法
JP6001456B2 (ja) * 2010-12-28 2016-10-05 中外製薬株式会社 動物細胞の培養方法
JP2021500069A (ja) * 2017-10-23 2021-01-07 プロゲン・シーオー., エルティーディー.Progen Co., Ltd. 改変ｅｇｆタンパク質、その製造方法及びその使用

Also Published As

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US6872549B2 (en) 2005-03-29
EP1497444B1 (en) 2015-11-04
US7452695B2 (en) 2008-11-18
AU2003220529A1 (en) 2003-10-13
WO2003083066A3 (en) 2004-02-26
MXPA04009381A (es) 2005-01-25
JP4414466B2 (ja) 2010-02-10
WO2003083066A2 (en) 2003-10-09
JP2008167760A (ja) 2008-07-24
AU2003220529B2 (en) 2006-09-07
PL376821A1 (pl) 2006-01-09
CA2480121C (en) 2012-02-28
JP2009082138A (ja) 2009-04-23
ES2557741T3 (es) 2016-01-28
JP4414472B2 (ja) 2010-02-10
EP1497444A4 (en) 2006-08-30
CA2480121A1 (en) 2003-10-09
US20030211579A1 (en) 2003-11-13
EP1497444A2 (en) 2005-01-19
US20050233415A1 (en) 2005-10-20

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