JP2005519873A - カテーテル注入可能なデポー組成物およびそれらの使用 - Google Patents
カテーテル注入可能なデポー組成物およびそれらの使用 Download PDFInfo
- Publication number
- JP2005519873A JP2005519873A JP2003543644A JP2003543644A JP2005519873A JP 2005519873 A JP2005519873 A JP 2005519873A JP 2003543644 A JP2003543644 A JP 2003543644A JP 2003543644 A JP2003543644 A JP 2003543644A JP 2005519873 A JP2005519873 A JP 2005519873A
- Authority
- JP
- Japan
- Prior art keywords
- injectable depot
- polymer
- weight
- catheter
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33630701P | 2001-11-14 | 2001-11-14 | |
| US39988202P | 2002-07-31 | 2002-07-31 | |
| PCT/US2002/036716 WO2003041757A2 (en) | 2001-11-14 | 2002-11-14 | Catheter injectable depot compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005519873A true JP2005519873A (ja) | 2005-07-07 |
| JP2005519873A5 JP2005519873A5 (enExample) | 2006-03-09 |
Family
ID=26990149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003543644A Pending JP2005519873A (ja) | 2001-11-14 | 2002-11-14 | カテーテル注入可能なデポー組成物およびそれらの使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7829109B2 (enExample) |
| EP (1) | EP1446101B1 (enExample) |
| JP (1) | JP2005519873A (enExample) |
| KR (1) | KR20040058101A (enExample) |
| AT (1) | ATE502621T1 (enExample) |
| AU (1) | AU2002359407B2 (enExample) |
| BR (1) | BR0206987A (enExample) |
| CA (1) | CA2467239A1 (enExample) |
| DE (1) | DE60239556D1 (enExample) |
| IL (1) | IL162001A0 (enExample) |
| MX (1) | MXPA04004665A (enExample) |
| NO (1) | NO20033178L (enExample) |
| NZ (1) | NZ533436A (enExample) |
| WO (1) | WO2003041757A2 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005533081A (ja) * | 2002-06-25 | 2005-11-04 | アルザ・コーポレーシヨン | 短期間デポ調剤 |
| JP2007511524A (ja) * | 2003-11-14 | 2007-05-10 | アルザ・コーポレーシヨン | 薬品送達ビヒクル中の賦形剤 |
| JP2013517015A (ja) * | 2010-01-13 | 2013-05-16 | ビショフ、ゲオルグ | 腸を一時的に閉塞するための組成物 |
| US10201496B2 (en) | 2002-06-25 | 2019-02-12 | Durect Corporation | Short duration depot formulations |
| US11400019B2 (en) | 2020-01-13 | 2022-08-02 | Durect Corporation | Sustained release drug delivery systems with reduced impurities and related methods |
| US12433877B2 (en) | 2021-01-12 | 2025-10-07 | Durect Corporation | Sustained release drug delivery systems and related methods |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1372729T3 (da) | 2001-02-23 | 2009-06-22 | Genentech Inc | Nedbrydelige polymere til injektion |
| US7829109B2 (en) | 2001-11-14 | 2010-11-09 | Durect Corporation | Catheter injectable depot compositions and uses thereof |
| WO2003041685A1 (en) * | 2001-11-14 | 2003-05-22 | Alza Corporation | Injectable depot composition |
| AU2003256849A1 (en) * | 2002-07-31 | 2004-02-16 | Alza Corporation | Injectable multimodal polymer depot compositions and uses thereof |
| AU2002359397B2 (en) * | 2002-07-31 | 2009-01-29 | Durect Corporation | Injectable depot compositions and uses thereof |
| US7368126B2 (en) * | 2002-11-06 | 2008-05-06 | Guohua Chen | Controlled release depot formulations |
| US9107751B2 (en) | 2002-12-12 | 2015-08-18 | Warsaw Orthopedic, Inc. | Injectable and moldable bone substitute materials |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
| EP1442753B1 (en) * | 2003-02-03 | 2007-02-21 | Polaschegg, Hans-Dietrich, Dr.techn. | Composition for the prevention of indwelling device related infection |
| BRPI0408925A (pt) * | 2003-03-31 | 2006-04-04 | Alza Corp | veìculos de fase simples não-aquosos e formulações utilizando tais veìculos |
| KR20050120767A (ko) * | 2003-03-31 | 2005-12-23 | 알자 코포레이션 | 삼투성 전달 시스템 및 삼투성 전달 시스템의 기동 시간감소 방법 |
| TW200507893A (en) * | 2003-03-31 | 2005-03-01 | Alza Corp | Osmotic pump with means for dissipating internal pressure |
| WO2005046747A2 (en) * | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Intravascular devices and fibrosis-inducing agents |
| CN1886152A (zh) | 2003-11-14 | 2006-12-27 | 阿尔萨公司 | 在药物辐射赋形剂制剂中药物氧化的最小化 |
| US20050281879A1 (en) * | 2003-11-14 | 2005-12-22 | Guohua Chen | Excipients in drug delivery vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| JP2008528698A (ja) * | 2005-02-03 | 2008-07-31 | インターシア セラピューティクス,インコーポレイティド | 埋め込み可能なインターフェロン含有デバイス |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US20060216242A1 (en) * | 2005-02-03 | 2006-09-28 | Rohloff Catherine M | Suspending vehicles and pharmaceutical suspensions for drug dosage forms |
| US20070021411A1 (en) * | 2005-05-11 | 2007-01-25 | Cloyd James C | Supersaturated benzodiazepine solutions and their delivery |
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| US20070048288A1 (en) * | 2005-08-30 | 2007-03-01 | Lyu Suping | Shear thinning polymer cell delivery compositions |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| ATE481963T1 (de) | 2006-05-30 | 2010-10-15 | Intarcia Therapeutics Inc | Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem |
| AU2007284759B2 (en) | 2006-08-09 | 2010-10-28 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
| MX2009011123A (es) | 2007-04-23 | 2009-11-02 | Intarcia Therapeutics Inc | Formulaciones de suspensiones de peptidos insulinotropicos y sus usos. |
| WO2008143992A2 (en) | 2007-05-18 | 2008-11-27 | Durect Corporation | Improved depot formulations |
| MX354603B (es) | 2007-05-25 | 2018-03-13 | Indivior Uk Ltd | Formulaciones de transferencia sostenida de compuestos de risperidona. |
| US8153112B2 (en) * | 2007-08-03 | 2012-04-10 | Warsaw Orthopedic, Inc. | Compositions and methods for treating cavity conditions |
| US8946208B2 (en) * | 2007-08-31 | 2015-02-03 | Archimedes Development Limited | Non-aqueous pharmaceutical composition |
| EP2030610A1 (en) * | 2007-08-31 | 2009-03-04 | Archimedes Development Limited | Non-aqueous pharmaceutical compositions |
| US20090181068A1 (en) * | 2008-01-14 | 2009-07-16 | Dunn Richard L | Low Viscosity Liquid Polymeric Delivery System |
| DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
| US20100280595A1 (en) * | 2009-04-30 | 2010-11-04 | Medtronic Vascular, Inc. | Method and Device for Localized Administration of Calcium Chelating Agent |
| KR102093612B1 (ko) | 2009-09-28 | 2020-03-26 | 인타르시아 세라퓨틱스 인코포레이티드 | 실질 항정상태 약물 전달의 신속 확립 및/또는 종결 |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US20150032088A1 (en) | 2012-01-24 | 2015-01-29 | The Methodist Hospital Research Institute | Sustained drug delivery from solid state compositions with nanochannel membranes |
| CN102716470B (zh) * | 2012-06-28 | 2015-02-04 | 中国人民解放军第三军医大学第三附属医院 | 一种治疗周围神经损伤的药物组合物 |
| US9827321B2 (en) | 2012-08-14 | 2017-11-28 | The Trustees Of The University Of Pennsylvania | Stabilizing shear-thinning hydrogels |
| US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
| CN115804749A (zh) | 2013-03-11 | 2023-03-17 | 度瑞公司 | 包含高粘度液体载体的可注射控制释放组合物 |
| US20160303242A1 (en) | 2013-12-09 | 2016-10-20 | Durect Corporation | Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| KR102650751B1 (ko) | 2015-06-03 | 2024-03-22 | 인타르시아 세라퓨틱스 인코포레이티드 | 임플란트 배치 및 제거 시스템들 |
| CA3024479A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| MX2019008006A (es) | 2017-01-03 | 2019-08-29 | Intarcia Therapeutics Inc | Metodos que comprenden la administracion continua de un agonista del receptor de glp-1 y la co-administracion de un farmaco. |
| US10799289B2 (en) | 2018-10-15 | 2020-10-13 | Avent, Inc. | Compositions, systems, kits, and methods for neural ablation |
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- 2002-11-14 MX MXPA04004665A patent/MXPA04004665A/es not_active Application Discontinuation
- 2002-11-14 AT AT02793942T patent/ATE502621T1/de not_active IP Right Cessation
- 2002-11-14 WO PCT/US2002/036716 patent/WO2003041757A2/en not_active Ceased
- 2002-11-14 AU AU2002359407A patent/AU2002359407B2/en not_active Ceased
- 2002-11-14 KR KR10-2003-7009401A patent/KR20040058101A/ko not_active Ceased
- 2002-11-14 BR BR0206987-3A patent/BR0206987A/pt not_active IP Right Cessation
- 2002-11-14 IL IL16200102A patent/IL162001A0/xx unknown
- 2002-11-14 CA CA002467239A patent/CA2467239A1/en not_active Abandoned
- 2002-11-14 NZ NZ533436A patent/NZ533436A/en unknown
- 2002-11-14 EP EP02793942A patent/EP1446101B1/en not_active Expired - Lifetime
- 2002-11-14 DE DE60239556T patent/DE60239556D1/de not_active Expired - Lifetime
- 2002-11-14 JP JP2003543644A patent/JP2005519873A/ja active Pending
-
2003
- 2003-07-11 NO NO20033178A patent/NO20033178L/no not_active Application Discontinuation
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2010
- 2010-10-18 US US12/925,408 patent/US20110046606A1/en not_active Abandoned
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| JP4916887B2 (ja) * | 2003-11-14 | 2012-04-18 | アルザ・コーポレーシヨン | 薬品送達ビヒクル中の賦形剤 |
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Also Published As
| Publication number | Publication date |
|---|---|
| US20110046606A1 (en) | 2011-02-24 |
| ATE502621T1 (de) | 2011-04-15 |
| NO20033178L (no) | 2003-09-04 |
| IL162001A0 (en) | 2005-11-20 |
| US7829109B2 (en) | 2010-11-09 |
| EP1446101B1 (en) | 2011-03-23 |
| US20030180364A1 (en) | 2003-09-25 |
| KR20040058101A (ko) | 2004-07-03 |
| AU2002359407B2 (en) | 2008-02-28 |
| EP1446101A2 (en) | 2004-08-18 |
| WO2003041757A2 (en) | 2003-05-22 |
| NZ533436A (en) | 2007-10-26 |
| CA2467239A1 (en) | 2003-05-22 |
| DE60239556D1 (de) | 2011-05-05 |
| NO20033178D0 (no) | 2003-07-11 |
| BR0206987A (pt) | 2004-02-10 |
| MXPA04004665A (es) | 2004-09-10 |
| WO2003041757A3 (en) | 2003-09-12 |
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