JP2005518336A - Vegf受容体に結合する二重特異性抗体 - Google Patents
Vegf受容体に結合する二重特異性抗体 Download PDFInfo
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- JP2005518336A JP2005518336A JP2003508383A JP2003508383A JP2005518336A JP 2005518336 A JP2005518336 A JP 2005518336A JP 2003508383 A JP2003508383 A JP 2003508383A JP 2003508383 A JP2003508383 A JP 2003508383A JP 2005518336 A JP2005518336 A JP 2005518336A
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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| US30129901P | 2001-06-26 | 2001-06-26 | |
| PCT/US2002/020332 WO2003002144A1 (en) | 2001-06-26 | 2002-06-26 | Bispecific antibodies that bind to vegf receptors |
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| JP2005518336A true JP2005518336A (ja) | 2005-06-23 |
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| JP2003508383A Pending JP2005518336A (ja) | 2001-06-26 | 2002-06-26 | Vegf受容体に結合する二重特異性抗体 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005526482A (ja) * | 2001-08-10 | 2005-09-08 | イムクローン システムズ インコーポレイティド | Vegfr−1を発現する幹細胞の単離および動員 |
| JP2013506419A (ja) * | 2009-10-01 | 2013-02-28 | アメリカ合衆国 | 抗血管内皮増殖因子受容体−2キメラ抗原受容体及び癌の治療のためのその使用 |
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| ATE510561T1 (de) | 2002-03-04 | 2011-06-15 | Imclone Llc | Kdr-spezifische menschliche antikörper und ihre verwendung |
| GB0305702D0 (en) * | 2003-03-12 | 2003-04-16 | Univ Birmingham | Bispecific antibodies |
| EP1682584B1 (en) | 2003-11-13 | 2013-04-17 | Hanmi Science Co., Ltd. | A pharmaceutical composition comprising an immunoglobulin fc region as a carrier |
| WO2005077065A2 (en) * | 2004-02-09 | 2005-08-25 | The Regents Of The University Of California | Selective high-affinity polydentate ligands and methods of making such |
| US20050282233A1 (en) * | 2004-03-05 | 2005-12-22 | Ludwig Institute For Cancer Research | Multivalent antibody materials and methods for VEGF/PDGF family of growth factors |
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| EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
| GB0512225D0 (en) * | 2005-06-16 | 2005-07-27 | Univ Sheffield | Immunoglobulin molecules |
| US20080019979A1 (en) * | 2006-05-22 | 2008-01-24 | Feng Wang-Johanning | HERV-K Antigens, Antibodies, and Methods |
| US20090297530A1 (en) | 2006-05-22 | 2009-12-03 | Feng Wang-Johanning | Herv-k antigens, antibodies, and methods |
| CA2694396A1 (en) * | 2007-07-25 | 2009-01-29 | Astrazeneca Ab | Targeted binding agents directed to kdr and uses thereof - 035 |
| CA2721980C (en) | 2008-04-21 | 2017-01-03 | The Regents Of The University Of California | Selective high-affinity poly dentate ligands and methods of making such |
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- 2002-06-26 US US10/482,630 patent/US20040242851A1/en not_active Abandoned
- 2002-06-26 JP JP2003508383A patent/JP2005518336A/ja active Pending
- 2002-06-26 WO PCT/US2002/020332 patent/WO2003002144A1/en not_active Ceased
- 2002-06-26 EP EP02744670A patent/EP1411983A4/en not_active Withdrawn
- 2002-06-26 CA CA002452058A patent/CA2452058A1/en not_active Abandoned
- 2002-12-24 US US10/520,026 patent/US20090028859A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000021560A1 (en) * | 1998-10-09 | 2000-04-20 | Ludwig Institute For Cancer Research | Flt4 (VEGFR-3) AS A TARGET FOR TUMOR IMAGING AND ANTI-TUMOR THERAPY |
| WO2000044777A1 (en) * | 1999-01-29 | 2000-08-03 | Imclone Systems Incorporated | Antibodies specific to kdr and uses thereof |
| JP2004511430A (ja) * | 2000-05-24 | 2004-04-15 | イムクローン システムズ インコーポレイティド | 二重特異性免疫グロブリン様抗原結合蛋白および製造方法 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005526482A (ja) * | 2001-08-10 | 2005-09-08 | イムクローン システムズ インコーポレイティド | Vegfr−1を発現する幹細胞の単離および動員 |
| JP2013506419A (ja) * | 2009-10-01 | 2013-02-28 | アメリカ合衆国 | 抗血管内皮増殖因子受容体−2キメラ抗原受容体及び癌の治療のためのその使用 |
| US9522955B2 (en) | 2009-10-01 | 2016-12-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1411983A1 (en) | 2004-04-28 |
| EP1411983A4 (en) | 2006-06-21 |
| US20090028859A1 (en) | 2009-01-29 |
| WO2003002144A1 (en) | 2003-01-09 |
| CA2452058A1 (en) | 2003-01-09 |
| US20040242851A1 (en) | 2004-12-02 |
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