JP2005517037A5 - - Google Patents
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- Publication number
- JP2005517037A5 JP2005517037A5 JP2003567427A JP2003567427A JP2005517037A5 JP 2005517037 A5 JP2005517037 A5 JP 2005517037A5 JP 2003567427 A JP2003567427 A JP 2003567427A JP 2003567427 A JP2003567427 A JP 2003567427A JP 2005517037 A5 JP2005517037 A5 JP 2005517037A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- alginate
- sustained release
- bicarbonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 7
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 4
- 229940072056 alginate Drugs 0.000 claims 4
- 235000010443 alginic acid Nutrition 0.000 claims 4
- 229920000615 alginic acid Polymers 0.000 claims 4
- 238000013268 sustained release Methods 0.000 claims 4
- 239000012730 sustained-release form Substances 0.000 claims 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 3
- 208000007882 Gastritis Diseases 0.000 claims 3
- 208000008469 Peptic Ulcer Diseases 0.000 claims 3
- 201000006549 dyspepsia Diseases 0.000 claims 3
- 208000021302 gastroesophageal reflux disease Diseases 0.000 claims 3
- 208000000689 peptic esophagitis Diseases 0.000 claims 3
- 208000011906 peptic ulcer disease Diseases 0.000 claims 3
- 229920001515 polyalkylene glycol Polymers 0.000 claims 3
- 229920005862 polyol Polymers 0.000 claims 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical group [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical group [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 150000003077 polyols Chemical class 0.000 claims 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical group CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- -1 alkylene glycol Chemical compound 0.000 claims 1
- 229910000019 calcium carbonate Inorganic materials 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 235000010413 sodium alginate Nutrition 0.000 claims 1
- 229940005550 sodium alginate Drugs 0.000 claims 1
- 239000000661 sodium alginate Substances 0.000 claims 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 238000005550 wet granulation Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0203269A GB2384986B (en) | 2002-02-12 | 2002-02-12 | Compositions for the treatment of disorders of the upper gastrointestinal tract |
| GB0203269.6 | 2002-02-12 | ||
| PCT/GB2003/000593 WO2003068246A2 (en) | 2002-02-12 | 2003-02-07 | Improvements in or relating to compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005517037A JP2005517037A (ja) | 2005-06-09 |
| JP2005517037A5 true JP2005517037A5 (https=) | 2005-12-22 |
| JP4276545B2 JP4276545B2 (ja) | 2009-06-10 |
Family
ID=9930901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003567427A Expired - Fee Related JP4276545B2 (ja) | 2002-02-12 | 2003-02-07 | 改良組成物 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20050069583A1 (https=) |
| EP (1) | EP1474154B1 (https=) |
| JP (1) | JP4276545B2 (https=) |
| KR (1) | KR100976071B1 (https=) |
| CN (1) | CN1315483C (https=) |
| AT (1) | ATE297742T1 (https=) |
| AU (1) | AU2003205868B2 (https=) |
| CA (1) | CA2474520C (https=) |
| DE (1) | DE60300862T2 (https=) |
| ES (1) | ES2242939T3 (https=) |
| GB (1) | GB2384986B (https=) |
| MX (1) | MXPA04007779A (https=) |
| PL (1) | PL210931B1 (https=) |
| PT (1) | PT1474154E (https=) |
| RU (1) | RU2317087C2 (https=) |
| WO (1) | WO2003068246A2 (https=) |
| ZA (1) | ZA200405848B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005018613A1 (de) * | 2003-08-26 | 2005-03-03 | Mandapro Ag | Pellets für die orale applikation von pharmazeutischen wirkstoffen |
| JP2006342085A (ja) * | 2005-06-08 | 2006-12-21 | Kao Corp | Ｇｉｐ分泌抑制剤 |
| GB0515492D0 (en) * | 2005-07-28 | 2005-08-31 | Reckitt Benckiser Healthcare | Improvements in or relating to compositions,articles and methods |
| SE530184C2 (sv) * | 2005-12-23 | 2008-03-18 | Kjell Stenberg | Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater |
| EP1859786A1 (en) * | 2006-05-16 | 2007-11-28 | Frutarom Netherlands B.V. | A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (GERD) by specific polysaccharides |
| KR100919508B1 (ko) * | 2007-08-14 | 2009-09-28 | 강원대학교산학협력단 | 매트릭스에 칼슘 카보네이트를 함유한 알지네이트 입자 및그 제조방법 |
| GB0814376D0 (en) * | 2008-08-06 | 2008-09-10 | Reckitt Benckiser Healthcare | Formulation |
| WO2010092468A1 (en) * | 2009-02-13 | 2010-08-19 | Carlo Ghisalberti | Composition comprising alginates and d-limonene to treat gerd and dyspepsia |
| WO2010108494A1 (en) * | 2009-03-25 | 2010-09-30 | S-Biotek Holding Aps | Dayspepsia treatment with alginate |
| JP5909851B2 (ja) * | 2010-02-24 | 2016-04-27 | 大正製薬株式会社 | 易嚥下性錠剤 |
| KR20130091250A (ko) * | 2010-04-23 | 2013-08-16 | 에스-바이오텍 홀딩 에이피에스 | 위산 중화용 고체 약학 조성물 |
| KR101307293B1 (ko) * | 2011-05-24 | 2013-09-26 | 주식회사 인트로팜텍 | 알긴산 화합물을 포함하는 과립형 약학 조성물, 및 이의 제조방법 |
| LT2806880T (lt) | 2012-01-27 | 2017-08-25 | Institute Of Bioorganic Chemistry | Farmacinė kompozicija, kaip substancija antacidiniam vaistui nuo refliukso |
| FR3068039B1 (fr) | 2017-06-22 | 2020-07-10 | Jellynov | Composition auto-moussante en milieu acide et procede de preparation |
| CN110945063B (zh) | 2017-07-20 | 2022-08-16 | 索尔维公司 | 作为发泡剂的官能化的微粒碳酸氢盐、含有其的可发泡聚合物组合物及其在制造热塑性发泡聚合物中的用途 |
| IT201800002625A1 (it) * | 2018-02-13 | 2019-08-13 | Drugs Minerals And Generics Italia S R L In Forma Abbreviata D M G Italia S R L | Composizione in forma solida per uso nel trattamento dei sintomi extra-esofagei del reflusso gastrico |
| IL312094A (en) * | 2018-03-02 | 2024-06-01 | Pharagen Llc | Formulations treating acid reflux comprising sodium alginate |
| MX2024007707A (es) | 2021-12-22 | 2024-07-01 | Chemo Res S L | Producto de goma de mascar antiacida que no se traga, procedimiento para su preparacion y usos del mismo. |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1524740A (en) * | 1976-11-09 | 1978-09-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions for use in the suppression of gastric reflux |
| US4613497A (en) * | 1984-02-29 | 1986-09-23 | Health Products Development, Inc. | Dry, water-foamable pharmaceutical compositions |
| DE3580384D1 (de) * | 1984-04-09 | 1990-12-13 | Toyo Boseki | Praeparat mit verzoegerter freigabe zum aufbringen auf die schleimhaeute der mundhoehle. |
| US4818518A (en) * | 1984-11-16 | 1989-04-04 | Uop | Effervescent dentifrice |
| US4892739A (en) * | 1988-04-25 | 1990-01-09 | Ciba-Geigy Corporation | Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties |
| GB9010039D0 (en) * | 1990-05-03 | 1990-06-27 | Reckitt & Colmann Prod Ltd | Medicament preparation |
| US5817294A (en) * | 1990-11-02 | 1998-10-06 | Arnold; Michael J. | Plaque adsorbent oral composition and method |
| US5922351A (en) * | 1991-03-27 | 1999-07-13 | Bayer Corporation | Lubricants for use in tabletting |
| HU213203B (en) * | 1991-04-04 | 1997-03-28 | Procter & Gamble | Process for producing of ingestible pharmaceutical compositions comprising 3-(i-menthoxy)-propane-1,2-diol for treating upper gastrointestinal tract symptoms |
| JPH09504286A (ja) * | 1993-10-29 | 1997-04-28 | レキット アンド コールマン プロダクツ リミテッド | 発泡しうるゼラチンカプセル充填物 |
| GB9504599D0 (en) * | 1995-03-03 | 1995-04-26 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| US5705190A (en) * | 1995-12-19 | 1998-01-06 | Abbott Laboratories | Controlled release formulation for poorly soluble basic drugs |
| US5908636A (en) * | 1996-06-28 | 1999-06-01 | Mcneil-Ppc, Inc. | Fill material for soft gelatin pharmaceutical dosage form containing an antiflatulent |
| US6395307B1 (en) * | 1997-04-30 | 2002-05-28 | Reckitt Benckiser (Uk) Limited | Pourable alginate compositions |
| US6210699B1 (en) * | 1999-04-01 | 2001-04-03 | Watson Pharmaceuticals, Inc. | Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity |
| US20020119196A1 (en) * | 2000-12-21 | 2002-08-29 | Narendra Parikh | Texture masked particles containing an active ingredient |
-
2002
- 2002-02-12 GB GB0203269A patent/GB2384986B/en not_active Expired - Fee Related
-
2003
- 2003-02-07 AT AT03702746T patent/ATE297742T1/de not_active IP Right Cessation
- 2003-02-07 AU AU2003205868A patent/AU2003205868B2/en not_active Expired
- 2003-02-07 KR KR1020047012429A patent/KR100976071B1/ko not_active Expired - Fee Related
- 2003-02-07 MX MXPA04007779A patent/MXPA04007779A/es active IP Right Grant
- 2003-02-07 PL PL370141A patent/PL210931B1/pl unknown
- 2003-02-07 DE DE60300862T patent/DE60300862T2/de not_active Expired - Lifetime
- 2003-02-07 JP JP2003567427A patent/JP4276545B2/ja not_active Expired - Fee Related
- 2003-02-07 CN CNB038036762A patent/CN1315483C/zh not_active Expired - Lifetime
- 2003-02-07 WO PCT/GB2003/000593 patent/WO2003068246A2/en not_active Ceased
- 2003-02-07 PT PT03702746T patent/PT1474154E/pt unknown
- 2003-02-07 ES ES03702746T patent/ES2242939T3/es not_active Expired - Lifetime
- 2003-02-07 US US10/502,863 patent/US20050069583A1/en not_active Abandoned
- 2003-02-07 EP EP03702746A patent/EP1474154B1/en not_active Expired - Lifetime
- 2003-02-07 CA CA2474520A patent/CA2474520C/en not_active Expired - Fee Related
- 2003-02-07 RU RU2004127245/15A patent/RU2317087C2/ru active
-
2004
- 2004-07-22 ZA ZA200405848A patent/ZA200405848B/en unknown
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