JP2005517037A5 - - Google Patents
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- Publication number
- JP2005517037A5 JP2005517037A5 JP2003567427A JP2003567427A JP2005517037A5 JP 2005517037 A5 JP2005517037 A5 JP 2005517037A5 JP 2003567427 A JP2003567427 A JP 2003567427A JP 2003567427 A JP2003567427 A JP 2003567427A JP 2005517037 A5 JP2005517037 A5 JP 2005517037A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- alginate
- sustained release
- bicarbonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 7
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 4
- 229940072056 alginate Drugs 0.000 claims 4
- 235000010443 alginic acid Nutrition 0.000 claims 4
- 229920000615 alginic acid Polymers 0.000 claims 4
- 238000013268 sustained release Methods 0.000 claims 4
- 239000012730 sustained-release form Substances 0.000 claims 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 3
- 208000007882 Gastritis Diseases 0.000 claims 3
- 208000008469 Peptic Ulcer Diseases 0.000 claims 3
- 201000006549 dyspepsia Diseases 0.000 claims 3
- 208000021302 gastroesophageal reflux disease Diseases 0.000 claims 3
- 208000000689 peptic esophagitis Diseases 0.000 claims 3
- 208000011906 peptic ulcer disease Diseases 0.000 claims 3
- 229920001515 polyalkylene glycol Polymers 0.000 claims 3
- 229920005862 polyol Polymers 0.000 claims 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical group [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical group [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 150000003077 polyols Chemical class 0.000 claims 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical group CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- -1 alkylene glycol Chemical compound 0.000 claims 1
- 229910000019 calcium carbonate Inorganic materials 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 235000010413 sodium alginate Nutrition 0.000 claims 1
- 229940005550 sodium alginate Drugs 0.000 claims 1
- 239000000661 sodium alginate Substances 0.000 claims 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 238000005550 wet granulation Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0203269A GB2384986B (en) | 2002-02-12 | 2002-02-12 | Compositions for the treatment of disorders of the upper gastrointestinal tract |
| GB0203269.6 | 2002-02-12 | ||
| PCT/GB2003/000593 WO2003068246A2 (en) | 2002-02-12 | 2003-02-07 | Improvements in or relating to compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005517037A JP2005517037A (ja) | 2005-06-09 |
| JP2005517037A5 true JP2005517037A5 (https=) | 2005-12-22 |
| JP4276545B2 JP4276545B2 (ja) | 2009-06-10 |
Family
ID=9930901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003567427A Expired - Fee Related JP4276545B2 (ja) | 2002-02-12 | 2003-02-07 | 改良組成物 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20050069583A1 (https=) |
| EP (1) | EP1474154B1 (https=) |
| JP (1) | JP4276545B2 (https=) |
| KR (1) | KR100976071B1 (https=) |
| CN (1) | CN1315483C (https=) |
| AT (1) | ATE297742T1 (https=) |
| AU (1) | AU2003205868B2 (https=) |
| CA (1) | CA2474520C (https=) |
| DE (1) | DE60300862T2 (https=) |
| ES (1) | ES2242939T3 (https=) |
| GB (1) | GB2384986B (https=) |
| MX (1) | MXPA04007779A (https=) |
| PL (1) | PL210931B1 (https=) |
| PT (1) | PT1474154E (https=) |
| RU (1) | RU2317087C2 (https=) |
| WO (1) | WO2003068246A2 (https=) |
| ZA (1) | ZA200405848B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005018613A1 (de) * | 2003-08-26 | 2005-03-03 | Mandapro Ag | Pellets für die orale applikation von pharmazeutischen wirkstoffen |
| JP2006342085A (ja) * | 2005-06-08 | 2006-12-21 | Kao Corp | Ｇｉｐ分泌抑制剤 |
| GB0515492D0 (en) * | 2005-07-28 | 2005-08-31 | Reckitt Benckiser Healthcare | Improvements in or relating to compositions,articles and methods |
| SE530184C2 (sv) * | 2005-12-23 | 2008-03-18 | Kjell Stenberg | Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater |
| EP1859786A1 (en) * | 2006-05-16 | 2007-11-28 | Frutarom Netherlands B.V. | A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (GERD) by specific polysaccharides |
| KR100919508B1 (ko) * | 2007-08-14 | 2009-09-28 | 강원대학교산학협력단 | 매트릭스에 칼슘 카보네이트를 함유한 알지네이트 입자 및그 제조방법 |
| GB0814376D0 (en) * | 2008-08-06 | 2008-09-10 | Reckitt Benckiser Healthcare | Formulation |
| WO2010092468A1 (en) * | 2009-02-13 | 2010-08-19 | Carlo Ghisalberti | Composition comprising alginates and d-limonene to treat gerd and dyspepsia |
| WO2010108494A1 (en) * | 2009-03-25 | 2010-09-30 | S-Biotek Holding Aps | Dayspepsia treatment with alginate |
| JP5909851B2 (ja) * | 2010-02-24 | 2016-04-27 | 大正製薬株式会社 | 易嚥下性錠剤 |
| EA024050B1 (ru) * | 2010-04-23 | 2016-08-31 | С-БИОТЕК ХОЛДИНГ АпС | Твердая фармацевтическая композиция для нейтрализации желудочной кислоты |
| KR101307293B1 (ko) * | 2011-05-24 | 2013-09-26 | 주식회사 인트로팜텍 | 알긴산 화합물을 포함하는 과립형 약학 조성물, 및 이의 제조방법 |
| EP2806880B2 (en) | 2012-01-27 | 2020-04-22 | Institute of Bioorganic Chemistry | Pharmaceutical composition as a substance for antireflux antacid drug |
| FR3068039B1 (fr) | 2017-06-22 | 2020-07-10 | Jellynov | Composition auto-moussante en milieu acide et procede de preparation |
| EP3655470B1 (en) | 2017-07-20 | 2023-09-20 | Solvay SA | Functionalized particulate bicarbonate as blowing agent, foamable polymer composition containing it, and its use in manufacturing a thermoplastic foamed polymer |
| IT201800002625A1 (it) * | 2018-02-13 | 2019-08-13 | Drugs Minerals And Generics Italia S R L In Forma Abbreviata D M G Italia S R L | Composizione in forma solida per uso nel trattamento dei sintomi extra-esofagei del reflusso gastrico |
| CA3092619A1 (en) * | 2018-03-02 | 2019-09-06 | Pharagen Llc | Formulations for treating acid reflux comprising sodium alginate |
| IL313305A (en) | 2021-12-22 | 2024-08-01 | Chemo Res S L | An antacid chewing gum product that is not ingestible, a process for its preparation and uses |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1524740A (en) * | 1976-11-09 | 1978-09-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions for use in the suppression of gastric reflux |
| US4613497A (en) * | 1984-02-29 | 1986-09-23 | Health Products Development, Inc. | Dry, water-foamable pharmaceutical compositions |
| US4740365A (en) * | 1984-04-09 | 1988-04-26 | Toyo Boseki Kabushiki Kaisha | Sustained-release preparation applicable to mucous membrane in oral cavity |
| US4818518A (en) * | 1984-11-16 | 1989-04-04 | Uop | Effervescent dentifrice |
| US4892739A (en) * | 1988-04-25 | 1990-01-09 | Ciba-Geigy Corporation | Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties |
| GB9010039D0 (en) * | 1990-05-03 | 1990-06-27 | Reckitt & Colmann Prod Ltd | Medicament preparation |
| US5817294A (en) * | 1990-11-02 | 1998-10-06 | Arnold; Michael J. | Plaque adsorbent oral composition and method |
| US5922351A (en) * | 1991-03-27 | 1999-07-13 | Bayer Corporation | Lubricants for use in tabletting |
| BR9205827A (pt) * | 1991-04-04 | 1994-06-28 | Procter & Gamble | Composições farmacêuticas ingeriveis para tratamento de distúrbios do trato gastrintestinal superior |
| WO1995011668A1 (en) * | 1993-10-29 | 1995-05-04 | Reckitt & Colman Products Limited | Gelatin capsule fill able to foam |
| GB9504599D0 (en) * | 1995-03-03 | 1995-04-26 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| US5705190A (en) * | 1995-12-19 | 1998-01-06 | Abbott Laboratories | Controlled release formulation for poorly soluble basic drugs |
| US5908636A (en) * | 1996-06-28 | 1999-06-01 | Mcneil-Ppc, Inc. | Fill material for soft gelatin pharmaceutical dosage form containing an antiflatulent |
| US6395307B1 (en) * | 1997-04-30 | 2002-05-28 | Reckitt Benckiser (Uk) Limited | Pourable alginate compositions |
| US6210699B1 (en) * | 1999-04-01 | 2001-04-03 | Watson Pharmaceuticals, Inc. | Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity |
| US20020119196A1 (en) * | 2000-12-21 | 2002-08-29 | Narendra Parikh | Texture masked particles containing an active ingredient |
-
2002
- 2002-02-12 GB GB0203269A patent/GB2384986B/en not_active Expired - Fee Related
-
2003
- 2003-02-07 PT PT03702746T patent/PT1474154E/pt unknown
- 2003-02-07 WO PCT/GB2003/000593 patent/WO2003068246A2/en not_active Ceased
- 2003-02-07 DE DE60300862T patent/DE60300862T2/de not_active Expired - Lifetime
- 2003-02-07 AU AU2003205868A patent/AU2003205868B2/en not_active Expired
- 2003-02-07 MX MXPA04007779A patent/MXPA04007779A/es active IP Right Grant
- 2003-02-07 AT AT03702746T patent/ATE297742T1/de not_active IP Right Cessation
- 2003-02-07 KR KR1020047012429A patent/KR100976071B1/ko not_active Expired - Fee Related
- 2003-02-07 EP EP03702746A patent/EP1474154B1/en not_active Expired - Lifetime
- 2003-02-07 PL PL370141A patent/PL210931B1/pl unknown
- 2003-02-07 CA CA2474520A patent/CA2474520C/en not_active Expired - Fee Related
- 2003-02-07 US US10/502,863 patent/US20050069583A1/en not_active Abandoned
- 2003-02-07 JP JP2003567427A patent/JP4276545B2/ja not_active Expired - Fee Related
- 2003-02-07 ES ES03702746T patent/ES2242939T3/es not_active Expired - Lifetime
- 2003-02-07 CN CNB038036762A patent/CN1315483C/zh not_active Expired - Lifetime
- 2003-02-07 RU RU2004127245/15A patent/RU2317087C2/ru active
-
2004
- 2004-07-22 ZA ZA200405848A patent/ZA200405848B/en unknown
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