GB2384986B - Compositions for the treatment of disorders of the upper gastrointestinal tract - Google Patents
Compositions for the treatment of disorders of the upper gastrointestinal tractInfo
- Publication number
- GB2384986B GB2384986B GB0203269A GB0203269A GB2384986B GB 2384986 B GB2384986 B GB 2384986B GB 0203269 A GB0203269 A GB 0203269A GB 0203269 A GB0203269 A GB 0203269A GB 2384986 B GB2384986 B GB 2384986B
- Authority
- GB
- United Kingdom
- Prior art keywords
- disorders
- compositions
- treatment
- gastrointestinal tract
- upper gastrointestinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 title 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 229940072056 alginate Drugs 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- -1 alkylene glycol Chemical compound 0.000 abstract 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/734—Alginic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dental Preparations (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0203269A GB2384986B (en) | 2002-02-12 | 2002-02-12 | Compositions for the treatment of disorders of the upper gastrointestinal tract |
| CNB038036762A CN1315483C (zh) | 2002-02-12 | 2003-02-07 | 组合物内在或相关的改进 |
| PT03702746T PT1474154E (pt) | 2002-02-12 | 2003-02-07 | Melhorias em composicoes ou relacionadas com elas |
| DE60300862T DE60300862T2 (de) | 2002-02-12 | 2003-02-07 | Verbesserungen an oder in bezug auf arzneizusammensetzungen |
| AT03702746T ATE297742T1 (de) | 2002-02-12 | 2003-02-07 | Verbesserungen an oder in bezug auf arzneizusammensetzungen |
| US10/502,863 US20050069583A1 (en) | 2002-02-12 | 2003-02-07 | Compositions |
| PCT/GB2003/000593 WO2003068246A2 (en) | 2002-02-12 | 2003-02-07 | Improvements in or relating to compositions |
| AU2003205868A AU2003205868B2 (en) | 2002-02-12 | 2003-02-07 | Improvements in or relating to compositions |
| ES03702746T ES2242939T3 (es) | 2002-02-12 | 2003-02-07 | Mejoras a composiciones o relacionadas con las mismas. |
| EP03702746A EP1474154B1 (en) | 2002-02-12 | 2003-02-07 | Improvements in or relating to compositions |
| JP2003567427A JP4276545B2 (ja) | 2002-02-12 | 2003-02-07 | 改良組成物 |
| KR1020047012429A KR100976071B1 (ko) | 2002-02-12 | 2003-02-07 | 조성물 내에서의 또는 조성물에 관련된 개선책 |
| RU2004127245/15A RU2317087C2 (ru) | 2002-02-12 | 2003-02-07 | Улучшенные композиции и улучшения, связанные с композициями |
| PL370141A PL210931B1 (pl) | 2002-02-12 | 2003-02-07 | Kompozycja w postaci stałej nadająca się do połykania zawierająca alginian, wodorowęglan i/lub węglan, jej zastosowanie oraz sposób wytwarzania |
| CA2474520A CA2474520C (en) | 2002-02-12 | 2003-02-07 | Solid alginate compositions for use in treating gastric disorders |
| MXPA04007779A MXPA04007779A (es) | 2002-02-12 | 2003-02-07 | Mejoramiento en o relacionado a composiciones. |
| ZA200405848A ZA200405848B (en) | 2002-02-12 | 2004-07-22 | Improvements in or relating to compositions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0203269A GB2384986B (en) | 2002-02-12 | 2002-02-12 | Compositions for the treatment of disorders of the upper gastrointestinal tract |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB0203269D0 GB0203269D0 (en) | 2002-03-27 |
| GB2384986A GB2384986A (en) | 2003-08-13 |
| GB2384986B true GB2384986B (en) | 2004-01-07 |
Family
ID=9930901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0203269A Expired - Fee Related GB2384986B (en) | 2002-02-12 | 2002-02-12 | Compositions for the treatment of disorders of the upper gastrointestinal tract |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20050069583A1 (https=) |
| EP (1) | EP1474154B1 (https=) |
| JP (1) | JP4276545B2 (https=) |
| KR (1) | KR100976071B1 (https=) |
| CN (1) | CN1315483C (https=) |
| AT (1) | ATE297742T1 (https=) |
| AU (1) | AU2003205868B2 (https=) |
| CA (1) | CA2474520C (https=) |
| DE (1) | DE60300862T2 (https=) |
| ES (1) | ES2242939T3 (https=) |
| GB (1) | GB2384986B (https=) |
| MX (1) | MXPA04007779A (https=) |
| PL (1) | PL210931B1 (https=) |
| PT (1) | PT1474154E (https=) |
| RU (1) | RU2317087C2 (https=) |
| WO (1) | WO2003068246A2 (https=) |
| ZA (1) | ZA200405848B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005018613A1 (de) * | 2003-08-26 | 2005-03-03 | Mandapro Ag | Pellets für die orale applikation von pharmazeutischen wirkstoffen |
| JP2006342085A (ja) * | 2005-06-08 | 2006-12-21 | Kao Corp | Gip分泌抑制剤 |
| GB0515492D0 (en) * | 2005-07-28 | 2005-08-31 | Reckitt Benckiser Healthcare | Improvements in or relating to compositions,articles and methods |
| SE530184C2 (sv) * | 2005-12-23 | 2008-03-18 | Kjell Stenberg | Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater |
| EP1859786A1 (en) * | 2006-05-16 | 2007-11-28 | Frutarom Netherlands B.V. | A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (GERD) by specific polysaccharides |
| KR100919508B1 (ko) * | 2007-08-14 | 2009-09-28 | 강원대학교산학협력단 | 매트릭스에 칼슘 카보네이트를 함유한 알지네이트 입자 및그 제조방법 |
| GB0814376D0 (en) * | 2008-08-06 | 2008-09-10 | Reckitt Benckiser Healthcare | Formulation |
| WO2010092468A1 (en) * | 2009-02-13 | 2010-08-19 | Carlo Ghisalberti | Composition comprising alginates and d-limonene to treat gerd and dyspepsia |
| WO2010108494A1 (en) * | 2009-03-25 | 2010-09-30 | S-Biotek Holding Aps | Dayspepsia treatment with alginate |
| JP5909851B2 (ja) * | 2010-02-24 | 2016-04-27 | 大正製薬株式会社 | 易嚥下性錠剤 |
| KR20130091250A (ko) * | 2010-04-23 | 2013-08-16 | 에스-바이오텍 홀딩 에이피에스 | 위산 중화용 고체 약학 조성물 |
| KR101307293B1 (ko) * | 2011-05-24 | 2013-09-26 | 주식회사 인트로팜텍 | 알긴산 화합물을 포함하는 과립형 약학 조성물, 및 이의 제조방법 |
| LT2806880T (lt) | 2012-01-27 | 2017-08-25 | Institute Of Bioorganic Chemistry | Farmacinė kompozicija, kaip substancija antacidiniam vaistui nuo refliukso |
| FR3068039B1 (fr) | 2017-06-22 | 2020-07-10 | Jellynov | Composition auto-moussante en milieu acide et procede de preparation |
| CN110945063B (zh) | 2017-07-20 | 2022-08-16 | 索尔维公司 | 作为发泡剂的官能化的微粒碳酸氢盐、含有其的可发泡聚合物组合物及其在制造热塑性发泡聚合物中的用途 |
| IT201800002625A1 (it) * | 2018-02-13 | 2019-08-13 | Drugs Minerals And Generics Italia S R L In Forma Abbreviata D M G Italia S R L | Composizione in forma solida per uso nel trattamento dei sintomi extra-esofagei del reflusso gastrico |
| IL312094A (en) * | 2018-03-02 | 2024-06-01 | Pharagen Llc | Formulations treating acid reflux comprising sodium alginate |
| MX2024007707A (es) | 2021-12-22 | 2024-07-01 | Chemo Res S L | Producto de goma de mascar antiacida que no se traga, procedimiento para su preparacion y usos del mismo. |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4613497A (en) * | 1984-02-29 | 1986-09-23 | Health Products Development, Inc. | Dry, water-foamable pharmaceutical compositions |
| WO1995011668A1 (en) * | 1993-10-29 | 1995-05-04 | Reckitt & Colman Products Limited | Gelatin capsule fill able to foam |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1524740A (en) * | 1976-11-09 | 1978-09-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions for use in the suppression of gastric reflux |
| DE3580384D1 (de) * | 1984-04-09 | 1990-12-13 | Toyo Boseki | Praeparat mit verzoegerter freigabe zum aufbringen auf die schleimhaeute der mundhoehle. |
| US4818518A (en) * | 1984-11-16 | 1989-04-04 | Uop | Effervescent dentifrice |
| US4892739A (en) * | 1988-04-25 | 1990-01-09 | Ciba-Geigy Corporation | Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties |
| GB9010039D0 (en) * | 1990-05-03 | 1990-06-27 | Reckitt & Colmann Prod Ltd | Medicament preparation |
| US5817294A (en) * | 1990-11-02 | 1998-10-06 | Arnold; Michael J. | Plaque adsorbent oral composition and method |
| US5922351A (en) * | 1991-03-27 | 1999-07-13 | Bayer Corporation | Lubricants for use in tabletting |
| HU213203B (en) * | 1991-04-04 | 1997-03-28 | Procter & Gamble | Process for producing of ingestible pharmaceutical compositions comprising 3-(i-menthoxy)-propane-1,2-diol for treating upper gastrointestinal tract symptoms |
| GB9504599D0 (en) * | 1995-03-03 | 1995-04-26 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| US5705190A (en) * | 1995-12-19 | 1998-01-06 | Abbott Laboratories | Controlled release formulation for poorly soluble basic drugs |
| US5908636A (en) * | 1996-06-28 | 1999-06-01 | Mcneil-Ppc, Inc. | Fill material for soft gelatin pharmaceutical dosage form containing an antiflatulent |
| US6395307B1 (en) * | 1997-04-30 | 2002-05-28 | Reckitt Benckiser (Uk) Limited | Pourable alginate compositions |
| US6210699B1 (en) * | 1999-04-01 | 2001-04-03 | Watson Pharmaceuticals, Inc. | Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity |
| US20020119196A1 (en) * | 2000-12-21 | 2002-08-29 | Narendra Parikh | Texture masked particles containing an active ingredient |
-
2002
- 2002-02-12 GB GB0203269A patent/GB2384986B/en not_active Expired - Fee Related
-
2003
- 2003-02-07 AT AT03702746T patent/ATE297742T1/de not_active IP Right Cessation
- 2003-02-07 AU AU2003205868A patent/AU2003205868B2/en not_active Expired
- 2003-02-07 KR KR1020047012429A patent/KR100976071B1/ko not_active Expired - Fee Related
- 2003-02-07 MX MXPA04007779A patent/MXPA04007779A/es active IP Right Grant
- 2003-02-07 PL PL370141A patent/PL210931B1/pl unknown
- 2003-02-07 DE DE60300862T patent/DE60300862T2/de not_active Expired - Lifetime
- 2003-02-07 JP JP2003567427A patent/JP4276545B2/ja not_active Expired - Fee Related
- 2003-02-07 CN CNB038036762A patent/CN1315483C/zh not_active Expired - Lifetime
- 2003-02-07 WO PCT/GB2003/000593 patent/WO2003068246A2/en not_active Ceased
- 2003-02-07 PT PT03702746T patent/PT1474154E/pt unknown
- 2003-02-07 ES ES03702746T patent/ES2242939T3/es not_active Expired - Lifetime
- 2003-02-07 US US10/502,863 patent/US20050069583A1/en not_active Abandoned
- 2003-02-07 EP EP03702746A patent/EP1474154B1/en not_active Expired - Lifetime
- 2003-02-07 CA CA2474520A patent/CA2474520C/en not_active Expired - Fee Related
- 2003-02-07 RU RU2004127245/15A patent/RU2317087C2/ru active
-
2004
- 2004-07-22 ZA ZA200405848A patent/ZA200405848B/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4613497A (en) * | 1984-02-29 | 1986-09-23 | Health Products Development, Inc. | Dry, water-foamable pharmaceutical compositions |
| WO1995011668A1 (en) * | 1993-10-29 | 1995-05-04 | Reckitt & Colman Products Limited | Gelatin capsule fill able to foam |
Non-Patent Citations (1)
| Title |
|---|
| EPODOC Abstract of BG 103124 A (BALKANFARMA DUPNITSA AD) see abstract. * |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2384986A (en) | 2003-08-13 |
| DE60300862D1 (de) | 2005-07-21 |
| MXPA04007779A (es) | 2004-10-15 |
| GB0203269D0 (en) | 2002-03-27 |
| WO2003068246A2 (en) | 2003-08-21 |
| JP2005517037A (ja) | 2005-06-09 |
| PT1474154E (pt) | 2005-10-31 |
| DE60300862T2 (de) | 2006-05-11 |
| JP4276545B2 (ja) | 2009-06-10 |
| CN1630523A (zh) | 2005-06-22 |
| AU2003205868A1 (en) | 2003-09-04 |
| RU2004127245A (ru) | 2005-04-10 |
| ES2242939T3 (es) | 2005-11-16 |
| KR100976071B1 (ko) | 2010-08-17 |
| AU2003205868B2 (en) | 2007-05-17 |
| EP1474154B1 (en) | 2005-06-15 |
| PL210931B1 (pl) | 2012-03-30 |
| WO2003068246A3 (en) | 2003-12-18 |
| CA2474520C (en) | 2012-04-10 |
| PL370141A1 (en) | 2005-05-16 |
| RU2317087C2 (ru) | 2008-02-20 |
| EP1474154A2 (en) | 2004-11-10 |
| CA2474520A1 (en) | 2003-08-21 |
| US20050069583A1 (en) | 2005-03-31 |
| CN1315483C (zh) | 2007-05-16 |
| KR20040086364A (ko) | 2004-10-08 |
| ATE297742T1 (de) | 2005-07-15 |
| ZA200405848B (en) | 2006-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20080212 |