JP2005516114A5 - - Google Patents
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- Publication number
- JP2005516114A5 JP2005516114A5 JP2003564190A JP2003564190A JP2005516114A5 JP 2005516114 A5 JP2005516114 A5 JP 2005516114A5 JP 2003564190 A JP2003564190 A JP 2003564190A JP 2003564190 A JP2003564190 A JP 2003564190A JP 2005516114 A5 JP2005516114 A5 JP 2005516114A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- photoreactive
- moiety
- polymeric material
- functional moiety
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920000642 polymer Polymers 0.000 claims 51
- 239000000178 monomer Substances 0.000 claims 34
- 239000000463 material Substances 0.000 claims 33
- 125000003118 aryl group Chemical group 0.000 claims 18
- 238000000034 method Methods 0.000 claims 15
- 125000001424 substituent group Chemical group 0.000 claims 12
- 239000012491 analyte Substances 0.000 claims 10
- 239000000758 substrate Substances 0.000 claims 9
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 6
- 229920006037 cross link polymer Polymers 0.000 claims 6
- 125000004404 heteroalkyl group Chemical group 0.000 claims 6
- 238000003795 desorption Methods 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 229920001577 copolymer Polymers 0.000 claims 4
- 229920005684 linear copolymer Polymers 0.000 claims 4
- 239000002861 polymer material Substances 0.000 claims 4
- 239000002243 precursor Substances 0.000 claims 4
- XUEQYOOPNQCUKG-UHFFFAOYSA-N 2-cyano-3-[4-(2-methylprop-2-enoyloxy)phenyl]prop-2-enoic acid Chemical compound CC(=C)C(=O)OC1=CC=C(C=C(C#N)C(O)=O)C=C1 XUEQYOOPNQCUKG-UHFFFAOYSA-N 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 230000002209 hydrophobic effect Effects 0.000 claims 3
- 125000006850 spacer group Chemical group 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- SVMANJSNQHAWNU-UHFFFAOYSA-N 2,5-bis(2-methylprop-2-enoyloxy)benzoic acid Chemical compound CC(=C)C(=O)OC1=CC=C(OC(=O)C(C)=C)C(C(O)=O)=C1 SVMANJSNQHAWNU-UHFFFAOYSA-N 0.000 claims 2
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 claims 2
- PFKFTWBEEFSNDU-UHFFFAOYSA-N carbonyldiimidazole Chemical group C1=CN=CN1C(=O)N1C=CN=C1 PFKFTWBEEFSNDU-UHFFFAOYSA-N 0.000 claims 2
- 239000007789 gas Substances 0.000 claims 2
- 238000001616 ion spectroscopy Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- HMZGPNHSPWNGEP-UHFFFAOYSA-N octadecyl 2-methylprop-2-enoate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)C(C)=C HMZGPNHSPWNGEP-UHFFFAOYSA-N 0.000 claims 2
- 229920002959 polymer blend Polymers 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M acrylate group Chemical group C(C=C)(=O)[O-] NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 1
- 150000002118 epoxides Chemical class 0.000 claims 1
- 125000003700 epoxy group Chemical group 0.000 claims 1
- 229920001519 homopolymer Polymers 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M methacrylate group Chemical group C(C(=C)C)(=O)[O-] CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 1
- XJDOEOHKUPXLLC-UHFFFAOYSA-N phenacyl prop-2-enoate Chemical compound C=CC(=O)OCC(=O)C1=CC=CC=C1 XJDOEOHKUPXLLC-UHFFFAOYSA-N 0.000 claims 1
- 239000003505 polymerization initiator Substances 0.000 claims 1
- 238000006116 polymerization reaction Methods 0.000 claims 1
- 230000000379 polymerizing effect Effects 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 0 C*C(C(C)CNC)=O Chemical compound C*C(C(C)CNC)=O 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35197102P | 2002-01-25 | 2002-01-25 | |
| US40825502P | 2002-09-04 | 2002-09-04 | |
| US10/327,511 US20030207462A1 (en) | 2002-01-25 | 2002-12-19 | Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes |
| US10/326,219 US7276381B2 (en) | 2002-01-25 | 2002-12-20 | Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes |
| PCT/US2002/041197 WO2003064594A2 (en) | 2002-01-25 | 2002-12-20 | Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005516114A JP2005516114A (ja) | 2005-06-02 |
| JP2005516114A5 true JP2005516114A5 (enExample) | 2006-01-05 |
Family
ID=27671072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003564190A Pending JP2005516114A (ja) | 2002-01-25 | 2002-12-20 | 被分析物の脱離/イオン化に有用なエネルギー吸収部分を有するモノマーおよびポリマー |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7276381B2 (enExample) |
| EP (1) | EP1481244A4 (enExample) |
| JP (1) | JP2005516114A (enExample) |
| WO (1) | WO2003064594A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1578527A1 (en) | 2002-09-13 | 2005-09-28 | Ciphergen Biosystems, Inc. | Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays |
| US7045366B2 (en) | 2003-09-12 | 2006-05-16 | Ciphergen Biosystems, Inc. | Photocrosslinked hydrogel blend surface coatings |
| US6977370B1 (en) | 2003-04-07 | 2005-12-20 | Ciphergen Biosystems, Inc. | Off-resonance mid-IR laser desorption ionization |
| US7341838B2 (en) | 2003-04-17 | 2008-03-11 | Biosite Incorporated | Polypeptides related to natriuretic peptides and methods of their identification and use |
| CA2525938C (en) * | 2003-05-19 | 2015-06-30 | Toray Industries, Inc. | Low-autofluorescence resin support for immobilizing a selective binding substance |
| EP1694816B1 (en) | 2003-11-07 | 2013-08-28 | Ciphergen Biosystems, Inc. | Biomarkers for alzheimer's disease |
| WO2005073711A2 (en) | 2004-01-20 | 2005-08-11 | Pall Corporation | Chromatographic material for the absorption of proteins at physiological ionic strength |
| CA2560758A1 (en) * | 2004-04-21 | 2005-11-03 | Toray Industries, Inc. | Lab-on-chip substrate |
| WO2006039077A2 (en) * | 2004-09-29 | 2006-04-13 | Ciphergen Biosystems, Inc. | Host-guest enery-absorbing complex |
| DE102004053458A1 (de) * | 2004-11-05 | 2006-05-11 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Strukturierte polymere Träger für die Massenspektrometrie und Verfahren zu deren Herstellung |
| US20060254916A1 (en) * | 2005-05-16 | 2006-11-16 | Hernandez Juan J | Methods of forming microfluidic devices and uses thereof |
| US20060261267A1 (en) * | 2005-05-20 | 2006-11-23 | Agency For Science, Technology And Research | Composite MALDI matrix material and methods of using it and kits thereof in MALDI |
| EP2993474B1 (en) | 2005-06-24 | 2019-06-12 | Vermillion, Inc. | Biomarkers for ovarian cancer: beta-2 microglobulin |
| JP2007171003A (ja) | 2005-12-22 | 2007-07-05 | Fujifilm Corp | 質量分析用基板並びに分析方法および装置 |
| JP5357746B2 (ja) | 2006-03-11 | 2013-12-04 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 末梢性の動脈疾患のためのバイオマーカーとしてのβ−2ミクログロブリン |
| EP2087504A2 (en) * | 2006-11-23 | 2009-08-12 | Philips Intellectual Property & Standards GmbH | Device for separation and maldi analysis of an analyte in a sample |
| US7999221B2 (en) * | 2008-06-02 | 2011-08-16 | Bio-Rad Laboratories, Inc. | Mass spectrometric detection of material transferred to a surface |
| JP2010216945A (ja) * | 2009-03-16 | 2010-09-30 | Sumitomo Electric Ind Ltd | 分析法 |
| WO2011004308A1 (en) * | 2009-07-09 | 2011-01-13 | Koninklijke Philips Electronics N.V. | Surface coating for laser desorption ionization mass spectrometry of molecules |
| JP5411771B2 (ja) * | 2010-03-29 | 2014-02-12 | 富士フイルム株式会社 | 化合物、重合性組成物、高分子、及びフィルム |
| EP2805167B1 (en) | 2012-01-20 | 2020-04-22 | Adelaide Research & Innovation Pty Ltd | Biomarkers for gastric cancer and uses thereof |
| AU2013202668B2 (en) | 2012-12-24 | 2014-12-18 | Adelaide Research & Innovation Pty Ltd | Inhibition of cancer growth and metastasis |
| US10262850B2 (en) * | 2016-12-19 | 2019-04-16 | Perkinelmer Health Sciences Canada, Inc. | Inorganic and organic mass spectrometry systems and methods of using them |
| WO2019078145A1 (ja) * | 2017-10-20 | 2019-04-25 | Jsr株式会社 | 質量分析用試料を調製するための材料 |
| US11866779B2 (en) | 2018-02-28 | 2024-01-09 | Northeastern University | Jettison-MS for nucleic acid species |
| EP4185301A4 (en) | 2020-07-24 | 2025-05-07 | The Regents Of The University Of Michigan | Compositions and methods for detecting and treating high grade subtypes of uterine cancer |
| WO2022150659A1 (en) * | 2021-01-08 | 2022-07-14 | Cellanome, Inc. | Devices and methods for analyzing biological samples |
| JP2024502618A (ja) | 2021-01-08 | 2024-01-22 | セラノーム, インコーポレイテッド | 生体試料を分析するためのデバイスおよび方法 |
| JP7421170B2 (ja) * | 2021-03-16 | 2024-01-24 | 株式会社豊田中央研究所 | 有機シリカ基板、及びそれを用いたレーザー脱離/イオン化質量分析方法 |
| CN113325064A (zh) * | 2021-05-28 | 2021-08-31 | 华南农业大学 | 一种大气压化学电离质谱鉴定魅力峰乳化剂组成成分的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3070442A (en) * | 1958-07-18 | 1962-12-25 | Du Pont | Process for producing colored polymeric relief images and elements therefor |
| US3748133A (en) * | 1972-03-24 | 1973-07-24 | Eastman Kodak Co | Photopolymerizable compositions and elements and uses thereof |
| GB1425423A (en) * | 1972-04-26 | 1976-02-18 | Eastman Kodak Co | Photopolymerisable compositions |
| US5002582A (en) * | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
| US5512329A (en) * | 1982-09-29 | 1996-04-30 | Bsi Corporation | Substrate surface preparation |
| JPS5968731A (ja) * | 1982-10-12 | 1984-04-18 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
| JPH0471896A (ja) | 1990-07-12 | 1992-03-06 | Fuji Photo Film Co Ltd | 感熱記録材料 |
| DE69432791T2 (de) | 1993-05-28 | 2004-06-03 | Baylor College Of Medicine, Houston | Verfahren und massenspektrometer zur desorption und ionisierung von analyten |
| CA2205040C (en) * | 1993-11-12 | 2006-10-17 | Joseph A. Jarrell | Enhanced resolution maldi tof-ms sample surface |
| NO952329D0 (no) | 1995-06-13 | 1995-06-13 | Jotun As | Polymerer for grohemmende maling og fremgangsmåte for fremstilling derav |
| DE19628178C1 (de) * | 1996-07-12 | 1997-09-18 | Bruker Franzen Analytik Gmbh | Verfahren zum Beladen von Probenträgern für Massenspektrometer |
| JPH11165052A (ja) | 1997-12-04 | 1999-06-22 | Toray Ind Inc | 半透膜およびその製造方法 |
-
2002
- 2002-12-20 WO PCT/US2002/041197 patent/WO2003064594A2/en not_active Ceased
- 2002-12-20 US US10/326,219 patent/US7276381B2/en not_active Expired - Lifetime
- 2002-12-20 EP EP02806705A patent/EP1481244A4/en not_active Withdrawn
- 2002-12-20 JP JP2003564190A patent/JP2005516114A/ja active Pending
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