JP2005514366A - ３−置換オキシインドールβ３アゴニスト - Google Patents

３−置換オキシインドールβ３アゴニスト Download PDF

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Publication number
JP2005514366A
JP2005514366A JP2003545653A JP2003545653A JP2005514366A JP 2005514366 A JP2005514366 A JP 2005514366A JP 2003545653 A JP2003545653 A JP 2003545653A JP 2003545653 A JP2003545653 A JP 2003545653A JP 2005514366 A JP2005514366 A JP 2005514366A
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JP
Japan
Prior art keywords
mmol
alkyl
methyl
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003545653A
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English (en)
Japanese (ja)
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JP2005514366A5 (cg-RX-API-DMAC7.html
Inventor
ジョリー・アン・バスティアン
ゲルト・リューター
ダニエル・ジョン・ソール
テオ・ショッテン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JP2005514366A publication Critical patent/JP2005514366A/ja
Publication of JP2005514366A5 publication Critical patent/JP2005514366A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2003545653A 2001-11-20 2002-11-12 ３−置換オキシインドールβ３アゴニスト Pending JP2005514366A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33403401P 2001-11-20 2001-11-20
PCT/US2002/033624 WO2003044016A1 (en) 2001-11-20 2002-11-12 3-SUBSTITUTED OXINDOLE β3 AGONISTS

Publications (2)

Publication Number Publication Date
JP2005514366A true JP2005514366A (ja) 2005-05-19
JP2005514366A5 JP2005514366A5 (cg-RX-API-DMAC7.html) 2006-01-05

Family

ID=23305290

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003545653A Pending JP2005514366A (ja) 2001-11-20 2002-11-12 ３−置換オキシインドールβ３アゴニスト

Country Status (8)

Country Link
US (1) US7205407B2 (cg-RX-API-DMAC7.html)
EP (1) EP1448560B1 (cg-RX-API-DMAC7.html)
JP (1) JP2005514366A (cg-RX-API-DMAC7.html)
AT (1) ATE297925T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002347982A1 (cg-RX-API-DMAC7.html)
DE (1) DE60204718T2 (cg-RX-API-DMAC7.html)
ES (1) ES2242890T3 (cg-RX-API-DMAC7.html)
WO (1) WO2003044016A1 (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
AU2002347982A1 (en) 2003-06-10
US7205407B2 (en) 2007-04-17
DE60204718T2 (de) 2006-05-18
ES2242890T3 (es) 2005-11-16
EP1448560B1 (en) 2005-06-15
DE60204718D1 (de) 2005-07-21
EP1448560A1 (en) 2004-08-25
US20050020617A1 (en) 2005-01-27
WO2003044016A1 (en) 2003-05-30
ATE297925T1 (de) 2005-07-15

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