JP2005512522A5 - - Google Patents

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Publication number
JP2005512522A5
JP2005512522A5 JP2003538348A JP2003538348A JP2005512522A5 JP 2005512522 A5 JP2005512522 A5 JP 2005512522A5 JP 2003538348 A JP2003538348 A JP 2003538348A JP 2003538348 A JP2003538348 A JP 2003538348A JP 2005512522 A5 JP2005512522 A5 JP 2005512522A5
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JP
Japan
Prior art keywords
mut
polypeptide
nucleic acid
drugs
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003538348A
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English (en)
Japanese (ja)
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JP2005512522A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/034381 external-priority patent/WO2003035847A2/en
Publication of JP2005512522A publication Critical patent/JP2005512522A/ja
Publication of JP2005512522A5 publication Critical patent/JP2005512522A5/ja
Pending legal-status Critical Current

Links

JP2003538348A 2001-10-26 2002-10-25 Il−13ムテインタンパク質、抗体、組成物、方法および使用 Pending JP2005512522A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34371701P 2001-10-26 2001-10-26
PCT/US2002/034381 WO2003035847A2 (en) 2001-10-26 2002-10-25 Il-13 mutein proteins, antibodies, compositions, methods and uses

Publications (2)

Publication Number Publication Date
JP2005512522A JP2005512522A (ja) 2005-05-12
JP2005512522A5 true JP2005512522A5 (https=) 2006-01-05

Family

ID=23347323

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003538348A Pending JP2005512522A (ja) 2001-10-26 2002-10-25 Il−13ムテインタンパク質、抗体、組成物、方法および使用

Country Status (5)

Country Link
US (1) US20040023337A1 (https=)
EP (1) EP1578912A4 (https=)
JP (1) JP2005512522A (https=)
CA (1) CA2464695A1 (https=)
WO (1) WO2003035847A2 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040234499A1 (en) * 2001-10-26 2004-11-25 David Shealy Asthma-related anti-IL-13 immunoglobulin derived proteins, compositions, methods and uses
HK1079882B (en) 2002-06-14 2011-11-25 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of treating and preventing colitis involving il-13 and nk-t cells
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
EP1444989A1 (en) * 2003-02-07 2004-08-11 Giorgio Dr. Stassi Sensitizing cells for apoptosis by selectively blocking cytokines
KR101073590B1 (ko) * 2003-07-15 2011-10-14 메디뮨 리미티드 Il-13에 대한 인간 항체 분자
GB0407315D0 (en) 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
SG10201404273QA (en) 2003-12-23 2014-10-30 Genentech Inc Novel anti-il 13 antibodies and uses thereof
WO2005091853A2 (en) * 2004-02-27 2005-10-06 Centocor, Inc. Methods and compositions for treating il-13 related pathologies
AR049390A1 (es) * 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
US20070048785A1 (en) * 2004-06-09 2007-03-01 Lin Laura L Anti-IL-13 antibodies and complexes
JP2008520684A (ja) * 2004-11-17 2008-06-19 アブジェニックス・インコーポレーテッド Il−13に対する完全ヒトモノクローナル抗体
AU2006296399B2 (en) * 2005-09-30 2011-01-20 Medimmune Limited Interleukin-13 antibody composition
RU2421464C2 (ru) 2005-10-21 2011-06-20 Новартис Аг Человеческие антитела к il-13 и их терапевтическое применение
CA2656379A1 (en) * 2006-06-21 2007-12-27 Apogenix Gmbh Differential cytokine expression in human cancer
AU2007271349A1 (en) * 2006-07-06 2008-01-10 Apogenix Gmbh Human IL-4 muteins in combination with chemotherapeutics or pro-apoptotic agents in cancer therapy
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
US8399630B2 (en) * 2008-08-20 2013-03-19 Centocor Ortho Biotech Inc. Engineered anti-IL-13 antibodies, compositions, methods and uses
US9296785B2 (en) 2009-04-17 2016-03-29 Wake Forest University Health Sciences IL-13 receptor binding peptides
JP2012526840A (ja) * 2009-05-13 2012-11-01 プロテイン デリヴァリー ソリューションズ エルエルシー 膜貫通送達のための製剤系
TWI732259B (zh) 2010-12-16 2021-07-01 美商建南德克公司 關於th2抑制作用之診斷及治療
US20130344074A1 (en) 2011-03-16 2013-12-26 Sanofi Uses of a dual v region antibody-like protein
TWI679019B (zh) 2013-04-29 2019-12-11 法商賽諾菲公司 抗il-4/抗il-13之雙特異性抗體調配物
EP4331605A3 (en) 2013-09-13 2024-05-22 F. Hoffmann-La Roche AG Methods and compositions comprising purified recombinant polypeptides
ES2915378T3 (es) 2013-09-13 2022-06-22 Hoffmann La Roche Procedimientos para detectar y cuantificar una proteína de célula huésped en líneas celulares
EP3129497B1 (en) 2014-04-11 2021-09-08 Novartis AG Methods of selectively treating asthma using il-13 antagonists
TW201628647A (zh) 2014-06-27 2016-08-16 賽諾菲公司 抗-il4-il13雙特異性抗體
CN113101364B (zh) 2018-05-29 2023-12-01 康诺亚生物医药科技(成都)有限公司 一种自免疫抑制剂的开发和应用
WO2020242989A1 (en) 2019-05-24 2020-12-03 Sanofi Methods for treating systemic sclerosis
WO2021097327A1 (en) * 2019-11-13 2021-05-20 University Of Virginia Patent Foundation Treatment of clostridium difficile infections
WO2022122654A1 (en) 2020-12-07 2022-06-16 UCB Biopharma SRL Multi-specific antibodies and antibody combinations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000044407A2 (en) * 1999-02-01 2000-08-03 Amgen Canada Materials and methods to inhibit hodgkin and reed sternberg cell growth
US20040219149A1 (en) * 2001-06-08 2004-11-04 Yuhong Zhou Methods for the modulation of il-13
WO2001008660A2 (en) * 1999-08-02 2001-02-08 The Regents Of The University Of Michigan Targeted fiberless radiative effectors

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