JP2010534664A5 - - Google Patents

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Publication number
JP2010534664A5
JP2010534664A5 JP2010518314A JP2010518314A JP2010534664A5 JP 2010534664 A5 JP2010534664 A5 JP 2010534664A5 JP 2010518314 A JP2010518314 A JP 2010518314A JP 2010518314 A JP2010518314 A JP 2010518314A JP 2010534664 A5 JP2010534664 A5 JP 2010534664A5
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JP
Japan
Prior art keywords
fibrosis
pharmaceutical formulation
drug
protein
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010518314A
Other languages
English (en)
Japanese (ja)
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JP2010534664A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/070588 external-priority patent/WO2009015063A2/en
Publication of JP2010534664A publication Critical patent/JP2010534664A/ja
Publication of JP2010534664A5 publication Critical patent/JP2010534664A5/ja
Pending legal-status Critical Current

Links

JP2010518314A 2007-07-23 2008-07-21 Il−17拮抗薬を用いた線維症関連疾患治療の方法及び組成物 Pending JP2010534664A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95127007P 2007-07-23 2007-07-23
US95541407P 2007-08-13 2007-08-13
PCT/US2008/070588 WO2009015063A2 (en) 2007-07-23 2008-07-21 Methods and compositions for treating fibrosis related disorders using il-17 antagonists

Publications (2)

Publication Number Publication Date
JP2010534664A JP2010534664A (ja) 2010-11-11
JP2010534664A5 true JP2010534664A5 (https=) 2011-08-11

Family

ID=40282097

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010518314A Pending JP2010534664A (ja) 2007-07-23 2008-07-21 Il−17拮抗薬を用いた線維症関連疾患治療の方法及び組成物

Country Status (5)

Country Link
US (1) US20110091378A1 (https=)
EP (1) EP2182943B1 (https=)
JP (1) JP2010534664A (https=)
ES (1) ES2614735T3 (https=)
WO (1) WO2009015063A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201608871XA (en) 2008-05-05 2016-12-29 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
TWI474833B (zh) * 2009-04-01 2015-03-01 Genentech Inc 胰島素阻抗性疾病之治療
CA2759848C (en) 2009-05-05 2018-12-04 Novimmune S.A. Anti-il-17f antibodies and methods of use thereof
JP2011032170A (ja) * 2009-07-29 2011-02-17 Morinaga Milk Ind Co Ltd ヒト細胞il−17産生抑制剤
WO2011044563A2 (en) * 2009-10-10 2011-04-14 The Board Of Trustees Of The Leland Stanford Junior University Il-17 family cytokine compositions and uses
CA2823549A1 (en) * 2011-01-04 2012-07-12 Robert Nussenblatt Methods of treating age-related macular degeneration
EP3318571B1 (en) * 2011-03-16 2021-02-17 F. Hoffmann-La Roche AG Ion exchange chromatography with improved selectivity for the separation of polypeptide monomers, aggregates and fragments by modulation of the mobile phase
US9284283B2 (en) 2012-02-02 2016-03-15 Ensemble Therapeutics Corporation Macrocyclic compounds for modulating IL-17
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
CN109796534B (zh) * 2017-11-16 2021-08-10 北京比洋生物技术有限公司 抗il-17抗体/tnfr ecd融合蛋白及其用途

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5618920A (en) 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5576195A (en) 1985-11-01 1996-11-19 Xoma Corporation Vectors with pectate lyase signal sequence
DE122007000007I1 (de) 1986-04-09 2007-05-16 Genzyme Corp Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern
US4704692A (en) 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4873316A (en) 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
US4939666A (en) 1987-09-02 1990-07-03 Genex Corporation Incremental macromolecule construction methods
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DK0494955T3 (da) 1989-10-05 1998-10-26 Optein Inc Cellefri syntese og isolering af hidtil ukendte gener og polypeptider
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
AU8081491A (en) 1990-06-01 1991-12-31 Cetus Corporation Compositions and methods for identifying biologically active molecules
US5723286A (en) 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
US5580734A (en) 1990-07-13 1996-12-03 Transkaryotic Therapies, Inc. Method of producing a physical map contigous DNA sequences
WO1992005258A1 (en) 1990-09-20 1992-04-02 La Trobe University Gene encoding barley enzyme
CA2405246A1 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with alterred binding properties
CA2104698A1 (en) 1991-02-21 1992-08-22 John J. Toole Aptamers specific for biomolecules and methods of making
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5733761A (en) 1991-11-05 1998-03-31 Transkaryotic Therapies, Inc. Protein production and protein delivery
ES2341666T3 (es) 1991-12-02 2010-06-24 Medimmune Limited Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
US5763733A (en) 1994-10-13 1998-06-09 Enzon, Inc. Antigen-binding fusion proteins
US5549551A (en) 1994-12-22 1996-08-27 Advanced Cardiovascular Systems, Inc. Adjustable length balloon catheter
NZ306653A (en) * 1995-03-23 1999-03-29 Immunex Corp Isolated dna il-17 receptors
US5656730A (en) 1995-04-07 1997-08-12 Enzon, Inc. Stabilized monomeric protein compositions
PT1538206E (pt) 1997-09-16 2010-04-12 Centocor Ortho Biotech Inc Método para a síntese química e construção completa de genes e genomas
US6670127B2 (en) 1997-09-16 2003-12-30 Egea Biosciences, Inc. Method for assembly of a polynucleotide encoding a target polypeptide
US20070160576A1 (en) * 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US20070053877A1 (en) * 2003-08-21 2007-03-08 Intermune, Inc. Methods of treating idiopathic pulmonary fibrosis
JP2008500338A (ja) * 2004-05-25 2008-01-10 イコス・コーポレイション 造血細胞の異常増殖を治療及び/又は予防する方法
MXPA06014465A (es) * 2004-06-10 2007-05-16 Zymogenetics Inc Zcytor14 soluble, anticuerpos anti-zcytor14 y moleculas de union y metodos de uso en inflamacion.
GB0417487D0 (en) * 2004-08-05 2004-09-08 Novartis Ag Organic compound
CA2596509A1 (en) * 2005-02-14 2006-08-24 Wyeth Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor
GT200600148A (es) * 2005-04-14 2006-11-22 Metodos para el tratamiento y la prevencion de fibrosis
CA2660463C (en) * 2006-08-11 2013-07-16 Schering Corporation Antibodies to il-17a

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