JP2005511491A5 - - Google Patents
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- Publication number
- JP2005511491A5 JP2005511491A5 JP2003511855A JP2003511855A JP2005511491A5 JP 2005511491 A5 JP2005511491 A5 JP 2005511491A5 JP 2003511855 A JP2003511855 A JP 2003511855A JP 2003511855 A JP2003511855 A JP 2003511855A JP 2005511491 A5 JP2005511491 A5 JP 2005511491A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- concentration
- composition
- kit according
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 7
- 239000000243 solution Substances 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 201000009273 Endometriosis Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000004403 Prostatic Hyperplasia Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- 229940011871 estrogen Drugs 0.000 claims 2
- 239000000262 estrogen Substances 0.000 claims 2
- 230000004720 fertilization Effects 0.000 claims 2
- 239000002474 gonadorelin antagonist Substances 0.000 claims 2
- 229940121381 gonadotrophin releasing hormone (gnrh) antagonists Drugs 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 230000002028 premature Effects 0.000 claims 2
- 230000001568 sexual effect Effects 0.000 claims 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 239000003433 contraceptive agent Substances 0.000 claims 1
- 230000002254 contraceptive effect Effects 0.000 claims 1
- 230000002611 ovarian Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0117057.0A GB0117057D0 (en) | 2001-07-12 | 2001-07-12 | Pharmaceutical composition |
| GB0117057.0 | 2001-07-12 | ||
| PCT/GB2002/003116 WO2003006049A1 (en) | 2001-07-12 | 2002-07-08 | Gonadotropin releasing hormone antagonists in gel-forming concentrations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005511491A JP2005511491A (ja) | 2005-04-28 |
| JP2005511491A5 true JP2005511491A5 (enExample) | 2007-05-24 |
| JP4845166B2 JP4845166B2 (ja) | 2011-12-28 |
Family
ID=9918396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003511855A Expired - Lifetime JP4845166B2 (ja) | 2001-07-12 | 2002-07-08 | ゲルを形成する濃度の性腺刺激ホルモン放出ホルモン拮抗物質 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20050245455A1 (enExample) |
| EP (1) | EP1404357B1 (enExample) |
| JP (1) | JP4845166B2 (enExample) |
| AR (1) | AR036337A1 (enExample) |
| AT (1) | ATE452648T1 (enExample) |
| DE (1) | DE60234831D1 (enExample) |
| DK (1) | DK1404357T3 (enExample) |
| ES (1) | ES2338217T3 (enExample) |
| GB (1) | GB0117057D0 (enExample) |
| MY (1) | MY139203A (enExample) |
| PT (1) | PT1404357E (enExample) |
| UY (1) | UY27378A1 (enExample) |
| WO (1) | WO2003006049A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| MXPA05003318A (es) | 2002-09-27 | 2005-09-12 | Zentaris Gmbh | Forma de administracion para peptidos farmaceuticamente activos con liberacion sostenida y metodo para la produccion de los mismos. |
| ES2555681T3 (es) | 2003-10-03 | 2016-01-07 | Thorn Bioscience, Llc | Procedimiento para la sincronización de la ovulación para la fecundación programada sin detección del celo |
| GB0511269D0 (en) | 2005-06-02 | 2005-07-13 | Creative Peptides Sweden Ab | Sustained release preparation of pro-insulin C-peptide |
| WO2008082563A2 (en) * | 2006-12-21 | 2008-07-10 | Stryker Corporation | Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents |
| TWI539959B (zh) | 2008-02-11 | 2016-07-01 | 菲瑞茵國際中心股份有限公司 | 治療轉移階段攝護腺癌的方法 |
| DK2421545T3 (en) | 2009-04-23 | 2018-03-12 | Jbs United Animal Health Ii Llc | PROCEDURE AND COMPOSITION TO SYNCHRONIZE THE TIME OF INSEMINATION. |
| JO3550B1 (ar) * | 2009-05-01 | 2020-07-05 | Ferring Int Center Sa | مركب لمعالجة سرطان البروستاتا |
| BRPI1010874A8 (pt) * | 2009-05-01 | 2018-01-02 | Ferring Bv | composição para o tratamento de câncer de próstata |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| WO2012055903A1 (en) | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| WO2013104745A1 (en) * | 2012-01-13 | 2013-07-18 | Ferring Bv | Pharmaceutical composition |
| NZ727679A (en) | 2012-06-01 | 2018-05-25 | Ferring Bv | Manufacture of degarelix |
| ITMI20121638A1 (it) * | 2012-10-02 | 2014-04-03 | Marco Sbracia | Utilizzo di degarelix nel trattamento dell'endometriosi e di patologie ad essa correlate |
| WO2014085674A1 (en) | 2012-11-28 | 2014-06-05 | Jbs United Animal Health Ii Llc | Method for synchronizing time of insemination in gilts |
| US10681261B2 (en) * | 2012-11-30 | 2020-06-09 | 3I Avi, Llc | Inspection system |
| TW201625218A (zh) * | 2014-04-18 | 2016-07-16 | Ｊｂｓ聯合動物保健有限責任公司 | 製造含ｇｎｒｈ凝膠之方法 |
| CN110248679A (zh) * | 2017-01-30 | 2019-09-17 | 安迪威有限公司 | 包含至少一种GnRH拮抗剂的组合物 |
| WO2019110688A1 (en) | 2017-12-05 | 2019-06-13 | Ferring B.V. | A composition comprising degarelix for use in the treatment of breast cancer |
| EP3560555A1 (en) * | 2018-04-26 | 2019-10-30 | LifeArc | A composition for treating one or more estrogen related diseases |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US200486A (en) * | 1878-02-19 | Improvement in apparatus for attaching harness to the shafts | ||
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| ATE144538T1 (de) * | 1991-04-25 | 1996-11-15 | Romano Deghenghi | Lhrh-antagonisten |
| SI9300468A (en) * | 1992-10-14 | 1994-06-30 | Hoffmann La Roche | Injectable composition for the sustained release of biologically active compounds |
| US5506207A (en) * | 1994-03-18 | 1996-04-09 | The Salk Institute For Biological Studies | GNRH antagonists XIII |
| US5595760A (en) * | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| US5860957A (en) * | 1997-02-07 | 1999-01-19 | Sarcos, Inc. | Multipathway electronically-controlled drug delivery system |
| US5925730A (en) * | 1997-04-11 | 1999-07-20 | Ferring Bv | GnRH antagonists |
| US5821230A (en) * | 1997-04-11 | 1998-10-13 | Ferring Bv | GnRH antagonist decapeptides |
| FR2776520B1 (fr) * | 1998-03-25 | 2000-05-05 | Sod Conseils Rech Applic | Nouvelles compositions pharmaceutiques destinees a la liberation prolongee de peptides et leur procede de preparation |
| US20020103131A1 (en) * | 2001-01-26 | 2002-08-01 | Jacobson Jill D. | Prevention of diabetes by administration of GnRH antagonists |
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
| EP1674082A1 (de) * | 2004-12-22 | 2006-06-28 | Zentaris GmbH | Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel |
| EP1891964A1 (en) * | 2006-08-08 | 2008-02-27 | AEterna Zentaris GmbH | Application of initial doses of LHRH analogues and maintenance doses of LHRH antagonists for the treatment of hormone-dependent cancers and corresponding pharmaceutical kits |
| US8105292B2 (en) * | 2008-02-11 | 2012-01-31 | Safety Syringes, Inc. | Reconstitution means for safety device |
| TWI539959B (zh) * | 2008-02-11 | 2016-07-01 | 菲瑞茵國際中心股份有限公司 | 治療轉移階段攝護腺癌的方法 |
| BRPI1010874A8 (pt) * | 2009-05-01 | 2018-01-02 | Ferring Bv | composição para o tratamento de câncer de próstata |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| WO2012055903A1 (en) * | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| EP2447276A1 (en) * | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) * | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| CN103841970A (zh) * | 2011-07-15 | 2014-06-04 | 辉凌公司 | 其中施用匹可硫酸盐组合物的结肠镜检查定时方法 |
-
2001
- 2001-07-12 GB GBGB0117057.0A patent/GB0117057D0/en not_active Ceased
-
2002
- 2002-07-03 MY MYPI20022511A patent/MY139203A/en unknown
- 2002-07-08 WO PCT/GB2002/003116 patent/WO2003006049A1/en not_active Ceased
- 2002-07-08 AT AT02749000T patent/ATE452648T1/de active
- 2002-07-08 US US10/483,325 patent/US20050245455A1/en not_active Abandoned
- 2002-07-08 EP EP02749000A patent/EP1404357B1/en not_active Expired - Lifetime
- 2002-07-08 ES ES02749000T patent/ES2338217T3/es not_active Expired - Lifetime
- 2002-07-08 JP JP2003511855A patent/JP4845166B2/ja not_active Expired - Lifetime
- 2002-07-08 DE DE60234831T patent/DE60234831D1/de not_active Expired - Lifetime
- 2002-07-08 DK DK02749000.2T patent/DK1404357T3/da active
- 2002-07-08 US US10/380,623 patent/US20040038903A1/en not_active Abandoned
- 2002-07-08 PT PT02749000T patent/PT1404357E/pt unknown
- 2002-07-11 AR ARP020102599A patent/AR036337A1/es not_active Application Discontinuation
- 2002-07-11 UY UY27378A patent/UY27378A1/es not_active Application Discontinuation
-
2008
- 2008-06-11 US US12/155,897 patent/US20090018085A1/en not_active Abandoned
-
2010
- 2010-10-08 US US12/901,270 patent/US20110053846A1/en not_active Abandoned
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