JP2005508893A5 - - Google Patents
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- Publication number
- JP2005508893A5 JP2005508893A5 JP2003522551A JP2003522551A JP2005508893A5 JP 2005508893 A5 JP2005508893 A5 JP 2005508893A5 JP 2003522551 A JP2003522551 A JP 2003522551A JP 2003522551 A JP2003522551 A JP 2003522551A JP 2005508893 A5 JP2005508893 A5 JP 2005508893A5
- Authority
- JP
- Japan
- Prior art keywords
- fucan
- pharmaceutical composition
- use according
- effective amount
- therapeutically effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 18
- 239000003814 drug Substances 0.000 claims 13
- 239000002552 dosage form Substances 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 8
- 206010003246 arthritis Diseases 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 239000000546 pharmaceutical excipient Substances 0.000 claims 5
- 229920000855 Fucoidan Polymers 0.000 claims 4
- 201000004681 Psoriasis Diseases 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 4
- 208000024891 symptom Diseases 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- 108091034117 Oligonucleotide Proteins 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000006072 paste Substances 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
- IAKHMKGGTNLKSZ-INIZCTEOSA-N (S)-colchicine Chemical compound C1([C@@H](NC(C)=O)CC2)=CC(=O)C(OC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC IAKHMKGGTNLKSZ-INIZCTEOSA-N 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 2
- 102000053642 Catalytic RNA Human genes 0.000 claims 2
- 108090000994 Catalytic RNA Proteins 0.000 claims 2
- 229920001661 Chitosan Polymers 0.000 claims 2
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 claims 2
- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 229940048053 acrylate Drugs 0.000 claims 2
- 229940072056 alginate Drugs 0.000 claims 2
- 229920000615 alginic acid Polymers 0.000 claims 2
- 235000010443 alginic acid Nutrition 0.000 claims 2
- 239000000074 antisense oligonucleotide Substances 0.000 claims 2
- 238000012230 antisense oligonucleotides Methods 0.000 claims 2
- QZPQTZZNNJUOLS-UHFFFAOYSA-N beta-lapachone Chemical compound C12=CC=CC=C2C(=O)C(=O)C2=C1OC(C)(C)CC2 QZPQTZZNNJUOLS-UHFFFAOYSA-N 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 229920002674 hyaluronan Polymers 0.000 claims 2
- 229960003160 hyaluronic acid Drugs 0.000 claims 2
- 239000007943 implant Substances 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- KQPYUDDGWXQXHS-UHFFFAOYSA-N juglone Chemical compound O=C1C=CC(=O)C2=C1C=CC=C2O KQPYUDDGWXQXHS-UHFFFAOYSA-N 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 239000004005 microsphere Substances 0.000 claims 2
- -1 plumbazine Chemical compound 0.000 claims 2
- 229920001983 poloxamer Polymers 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 108091092562 ribozyme Proteins 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 238000011200 topical administration Methods 0.000 claims 2
- 208000031295 Animal disease Diseases 0.000 claims 1
- 108020000948 Antisense Oligonucleotides Proteins 0.000 claims 1
- KLWPJMFMVPTNCC-UHFFFAOYSA-N Camptothecin Natural products CCC1(O)C(=O)OCC2=C1C=C3C4Nc5ccccc5C=C4CN3C2=O KLWPJMFMVPTNCC-UHFFFAOYSA-N 0.000 claims 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 1
- 108010036949 Cyclosporine Proteins 0.000 claims 1
- UETNIIAIRMUTSM-UHFFFAOYSA-N Jacareubin Natural products CC1(C)OC2=CC3Oc4c(O)c(O)ccc4C(=O)C3C(=C2C=C1)O UETNIIAIRMUTSM-UHFFFAOYSA-N 0.000 claims 1
- FBOZXECLQNJBKD-ZDUSSCGKSA-N L-methotrexate Chemical compound C=1N=C2N=C(N)N=C(N)C2=NC=1CN(C)C1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 FBOZXECLQNJBKD-ZDUSSCGKSA-N 0.000 claims 1
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 1
- 229930012538 Paclitaxel Natural products 0.000 claims 1
- VYTBDSUNRJYVHL-UHFFFAOYSA-N beta-Hydrojuglone Natural products O=C1CCC(=O)C2=C1C=CC=C2O VYTBDSUNRJYVHL-UHFFFAOYSA-N 0.000 claims 1
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical compound C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 claims 1
- 229940127093 camptothecin Drugs 0.000 claims 1
- 229960001265 ciclosporin Drugs 0.000 claims 1
- 229960001338 colchicine Drugs 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 229930182912 cyclosporin Natural products 0.000 claims 1
- VSJKWCGYPAHWDS-UHFFFAOYSA-N dl-camptothecin Natural products C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)C5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-UHFFFAOYSA-N 0.000 claims 1
- 229960003668 docetaxel Drugs 0.000 claims 1
- 229960004679 doxorubicin Drugs 0.000 claims 1
- VJJPUSNTGOMMGY-MRVIYFEKSA-N etoposide Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@H](C)OC[C@H]4O3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 VJJPUSNTGOMMGY-MRVIYFEKSA-N 0.000 claims 1
- 229960005420 etoposide Drugs 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 229960000485 methotrexate Drugs 0.000 claims 1
- 229960001156 mitoxantrone Drugs 0.000 claims 1
- KKZJGLLVHKMTCM-UHFFFAOYSA-N mitoxantrone Chemical compound O=C1C2=C(O)C=CC(O)=C2C(=O)C2=C1C(NCCNCCO)=CC=C2NCCNCCO KKZJGLLVHKMTCM-UHFFFAOYSA-N 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229960001592 paclitaxel Drugs 0.000 claims 1
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 1
- 150000004492 retinoid derivatives Chemical class 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 229960002930 sirolimus Drugs 0.000 claims 1
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- NCEXYHBECQHGNR-QZQOTICOSA-N sulfasalazine Chemical compound C1=C(O)C(C(=O)O)=CC(\N=N\C=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-QZQOTICOSA-N 0.000 claims 1
- 229960001940 sulfasalazine Drugs 0.000 claims 1
- NCEXYHBECQHGNR-UHFFFAOYSA-N sulfasalazine Natural products C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-UHFFFAOYSA-N 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
- 235000012711 vitamin K3 Nutrition 0.000 claims 1
- 239000011652 vitamin K3 Substances 0.000 claims 1
- 229940041603 vitamin k 3 Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31536201P | 2001-08-29 | 2001-08-29 | |
| US60/315,362 | 2001-08-29 | ||
| PCT/CA2002/001337 WO2003018033A1 (en) | 2001-08-29 | 2002-08-29 | Use of fucans in the treatment of adhesions, arthritis and psoriasis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009170270A Division JP2009280597A (ja) | 2001-08-29 | 2009-07-21 | 乾癬の治療へのフカン類の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005508893A JP2005508893A (ja) | 2005-04-07 |
| JP2005508893A5 true JP2005508893A5 (https=) | 2006-01-05 |
| JP4758063B2 JP4758063B2 (ja) | 2011-08-24 |
Family
ID=23224048
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003522551A Expired - Lifetime JP4758063B2 (ja) | 2001-08-29 | 2002-08-29 | 癒着、関節炎及び乾癬の治療へのフカン類の使用 |
| JP2009170270A Withdrawn JP2009280597A (ja) | 2001-08-29 | 2009-07-21 | 乾癬の治療へのフカン類の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009170270A Withdrawn JP2009280597A (ja) | 2001-08-29 | 2009-07-21 | 乾癬の治療へのフカン類の使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US6812220B2 (https=) |
| EP (1) | EP1420801B1 (https=) |
| JP (2) | JP4758063B2 (https=) |
| KR (2) | KR100910246B1 (https=) |
| CN (2) | CN1319540C (https=) |
| AT (1) | ATE376835T1 (https=) |
| AU (1) | AU2002325113B2 (https=) |
| CA (1) | CA2458853C (https=) |
| DE (1) | DE60223262T2 (https=) |
| DK (1) | DK1420801T3 (https=) |
| ES (1) | ES2295386T3 (https=) |
| MX (1) | MXPA04001876A (https=) |
| NZ (2) | NZ532015A (https=) |
| PT (1) | PT1420801E (https=) |
| WO (1) | WO2003018033A1 (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6632456B1 (en) * | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
| US7595378B2 (en) | 2001-06-13 | 2009-09-29 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (EGFR) |
| DK1539157T3 (da) | 2002-09-18 | 2013-10-07 | Univ Pennsylvania | Fremgangsmåde til hæmning af choroidal neovaskularisering |
| US8138265B2 (en) | 2003-01-10 | 2012-03-20 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| US8137688B2 (en) | 2003-01-10 | 2012-03-20 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| US6982298B2 (en) | 2003-01-10 | 2006-01-03 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| US7465766B2 (en) | 2004-01-08 | 2008-12-16 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| US8221758B2 (en) * | 2003-03-06 | 2012-07-17 | Cellmid Limited | Anti-midkine antibody for preventing post-laparotomy adhesions |
| BRPI0418384A (pt) * | 2003-05-30 | 2007-06-26 | Arc Pharmaceuticals Inc | composições farmacêuticas e métodos referentes à inibição de adesões fibrosas utilizando diversos agentes |
| KR20060085246A (ko) | 2003-09-18 | 2006-07-26 | 마커사이트, 인코포레이티드 | 경공막 전달 |
| JPWO2005089800A1 (ja) * | 2004-03-17 | 2008-01-31 | 株式会社ロコモジェン | ｈｓＨＲＤ３を含む医薬組成物 |
| CA2572804C (en) * | 2004-07-09 | 2013-04-02 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| CA2989941A1 (en) * | 2004-09-23 | 2006-03-30 | Arc Pharmaceuticals, Inc. | Pharmaceutical compostions and methods relating to inhibiting fibrous adhesions or inflammatory disease using low sulphate fucans |
| US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
| DK1848431T3 (en) | 2005-02-09 | 2016-04-18 | Santen Pharmaceutical Co Ltd | LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS |
| CN101119726B (zh) * | 2005-02-16 | 2011-02-02 | 麦仁斯有限公司 | 用于治疗或预防涉及肥胖、糖尿病、代谢综合症、神经变性疾病和线粒体功能障碍疾病的疾病的药物组合物 |
| US20060210692A1 (en) * | 2005-03-18 | 2006-09-21 | Mower Thomas E | Baby food composition |
| US7776365B2 (en) * | 2005-03-18 | 2010-08-17 | Sakura Properties, Llc | Article with skin protecting and moisturizing compound |
| US20060210514A1 (en) * | 2005-03-18 | 2006-09-21 | Mower Thomas E | Skin protection and moisturizing compositions and method of making the same |
| US20060210697A1 (en) * | 2005-03-18 | 2006-09-21 | Mower Thomas E | Infant formula composition |
| US20060210515A1 (en) * | 2005-03-18 | 2006-09-21 | Mower Thomas E | Hair growth formula |
| US20060210688A1 (en) * | 2005-03-18 | 2006-09-21 | Mower Thomas E | Dehydrated sports drink powder |
| US20060210496A1 (en) * | 2005-03-18 | 2006-09-21 | Mower Thomas E | Compositions for skin protection from ultraviolet damage |
| US20070020358A1 (en) * | 2005-03-18 | 2007-01-25 | Mower Thomas E | Sports drink concentrate |
| US7666448B2 (en) * | 2005-03-18 | 2010-02-23 | Sakura Properties, Llc | Skin cleansing article |
| US7749545B2 (en) * | 2005-03-18 | 2010-07-06 | Sakura Properties, Llc | Fucoidan compositions and methods for dietary and nutritional supplements |
| CA2603785C (en) | 2005-04-15 | 2014-07-22 | Roman Perez-Soler | Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy |
| US20070003669A1 (en) * | 2005-06-02 | 2007-01-04 | Troy Kearl | Fucoidan delivery system |
| WO2007028256A2 (en) * | 2005-09-09 | 2007-03-15 | Les Biotechnologies Oceanova Inc. | Polysaccharides compositions comprising fucans and galactans and their use to reduce extravasation and inflammation |
| KR20140093764A (ko) | 2006-02-09 | 2014-07-28 | 산텐 세이야꾸 가부시키가이샤 | 안정한 제제와 그 제조 및 사용 방법 |
| FR2897538B1 (fr) | 2006-02-23 | 2008-05-02 | Univ Paris Descartes | Utilisation de fucanes a des fins de greffe, d'ingenierie et de regeneration osseuses |
| ES2563288T3 (es) | 2006-03-23 | 2016-03-14 | Santen Pharmaceutical Co., Ltd | Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular |
| JP4814677B2 (ja) * | 2006-03-31 | 2011-11-16 | 株式会社荏原製作所 | 基板保持装置および研磨装置 |
| EP2043685B1 (en) | 2006-07-03 | 2015-12-23 | Genmab A/S | Prevention of rash in patients undergoing anti-egfr therapy |
| EP2249891B1 (en) | 2008-02-13 | 2016-05-25 | The Cleveland Clinic Foundation | Molecular enhancement of extracellular matrix and methods of use |
| US8815953B2 (en) | 2008-03-13 | 2014-08-26 | Spectrum Pharmaceuticals, Inc. | Formulations of vitamin K analogs for topical use |
| US8410180B2 (en) | 2008-04-30 | 2013-04-02 | The Cleveland Clinic Foundation | Methods to treat urinary incontinence |
| US20120071439A1 (en) * | 2009-03-25 | 2012-03-22 | Saburo Minami | Cartilage production promoter and prophylactic or therapeutic agent for diseases associated with cartilage damage |
| JO3676B1 (ar) * | 2009-07-27 | 2020-08-27 | Arc Medical Devices Inc | مركبات صيدلانية تضم فوكانات معدلة وطرق تتعلق بها |
| KR101528265B1 (ko) * | 2010-04-16 | 2015-06-11 | 코웨이 주식회사 | 베타-라파콘을 유효성분으로 포함하는 주름개선용 화장료 조성물 |
| EP2734213B1 (en) * | 2011-07-19 | 2018-06-06 | Baxalta GmbH | Resorption enhancers as additives to improve the oral formulation of non-anticoagulant sulfated polysaccharides |
| JP2018510905A (ja) * | 2015-02-16 | 2018-04-19 | エグザンシャル | 皮膚障害の予防又は治療のための組成物 |
| JP7160683B2 (ja) | 2016-04-29 | 2022-10-25 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 術後癒着の予防及び治療のための方法及び組成物 |
| US11446326B2 (en) * | 2018-07-27 | 2022-09-20 | ARC Medical Devices | Highly sulfated fucans for the treatment of fibrous adhesions |
| US12186334B2 (en) | 2018-07-27 | 2025-01-07 | ARC Medical Inc. | High-molecular-weight fucans for treating fibrous adhesions and other diseases and conditions |
| MX2021000866A (es) | 2019-03-05 | 2021-06-15 | Arc Medical Devices Inc | Sistemas y metodos para la filtracion de flujo tangencial de composiciones viscosas. |
| CN111617030B (zh) * | 2020-05-22 | 2021-09-07 | 广东药科大学 | 壳寡糖口服液及其在制备减肥药物中的应用 |
| WO2025166450A1 (en) * | 2024-02-05 | 2025-08-14 | ARC Medical Inc. | Compositions, devices, systems and methods relating to improvement of range of motion in joints |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3971848A (en) * | 1970-12-21 | 1976-07-27 | Kimitsu Chemical Laboratory Co. Ltd. | Lubricating composition for mucosa or epidermis |
| JPS58147064A (ja) | 1982-02-25 | 1983-09-01 | Fuji Electric Co Ltd | トランジスタ |
| EP0293826A3 (en) | 1987-06-02 | 1989-05-10 | Stichting REGA V.Z.W. | Therapeutic and prophylactic application of sulfated polysaccharides against aids |
| JPS6431707A (en) | 1987-07-28 | 1989-02-02 | Nikko Chemicals | Dermal agent for external use |
| JPH0714850B2 (ja) | 1987-09-29 | 1995-02-22 | 喜郎 板谷 | 化粧料 |
| JPH01313433A (ja) | 1988-06-13 | 1989-12-18 | Nippon Koutai Kenkyusho:Kk | 抗ｈｉｖ剤 |
| JP2853165B2 (ja) * | 1989-05-29 | 1999-02-03 | 味の素株式会社 | 体組織癒着防止膜 |
| FR2648463B1 (fr) * | 1989-06-14 | 1993-01-22 | Inst Fs Rech Expl Mer | Polysaccharides sulfates, agent anticoagulant et agent anticomplementaire obtenus a partir de fucanes d'algues brunes et leur procede d'obtention |
| US6096722A (en) * | 1990-08-14 | 2000-08-01 | Isis Pharmaceuticals Inc. | Antisense modulation of cell adhesion molecule expression and treatment of cell adhesion molecule-associated diseases |
| US5318890A (en) * | 1991-05-06 | 1994-06-07 | The Regents Of The University Of California | Assays for inhibitors of leukocyte adhesion |
| US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
| JP3403496B2 (ja) * | 1993-09-24 | 2003-05-06 | 株式会社ヤクルト本社 | 抗潰瘍剤およびヘリコバクター・ピロリの定着阻害剤 |
| JP3545789B2 (ja) * | 1993-09-30 | 2004-07-21 | 味の素ファルマ株式会社 | 腹腔内癒着防止剤 |
| FR2772618B1 (fr) * | 1997-12-18 | 2000-02-18 | Ifremer | Utilisation de fucane comme regulateur de la reconstruction des tissus conjonctifs |
| EP1117835A4 (en) * | 1998-10-02 | 2005-03-09 | Genzyme Corp | PREVENTION OF ADHERENCES |
| JP4267106B2 (ja) * | 1998-10-15 | 2009-05-27 | 株式会社クラレ | 癒着防止用材料 |
| JP2001052309A (ja) | 1999-08-06 | 2001-02-23 | Alps Electric Co Ltd | 薄膜磁気ヘッドおよびその製造方法 |
| SE0001631D0 (sv) * | 2000-05-04 | 2000-05-04 | Sahltech Ab | New use |
-
2002
- 2002-08-28 US US10/232,850 patent/US6812220B2/en not_active Expired - Lifetime
- 2002-08-29 PT PT02758008T patent/PT1420801E/pt unknown
- 2002-08-29 AU AU2002325113A patent/AU2002325113B2/en not_active Ceased
- 2002-08-29 DK DK02758008T patent/DK1420801T3/da active
- 2002-08-29 WO PCT/CA2002/001337 patent/WO2003018033A1/en not_active Ceased
- 2002-08-29 JP JP2003522551A patent/JP4758063B2/ja not_active Expired - Lifetime
- 2002-08-29 KR KR1020047003089A patent/KR100910246B1/ko not_active Expired - Fee Related
- 2002-08-29 CA CA2458853A patent/CA2458853C/en not_active Expired - Lifetime
- 2002-08-29 EP EP02758008A patent/EP1420801B1/en not_active Expired - Lifetime
- 2002-08-29 ES ES02758008T patent/ES2295386T3/es not_active Expired - Lifetime
- 2002-08-29 NZ NZ532015A patent/NZ532015A/en not_active IP Right Cessation
- 2002-08-29 KR KR1020097002751A patent/KR20090019926A/ko not_active Ceased
- 2002-08-29 NZ NZ547609A patent/NZ547609A/en not_active IP Right Cessation
- 2002-08-29 CN CNB028166930A patent/CN1319540C/zh not_active Expired - Fee Related
- 2002-08-29 CN CNA200710096370XA patent/CN101028283A/zh active Pending
- 2002-08-29 MX MXPA04001876A patent/MXPA04001876A/es active IP Right Grant
- 2002-08-29 DE DE60223262T patent/DE60223262T2/de not_active Expired - Lifetime
- 2002-08-29 AT AT02758008T patent/ATE376835T1/de active
-
2004
- 2004-09-13 US US10/940,413 patent/US20050074496A1/en not_active Abandoned
- 2004-10-05 US US10/958,759 patent/US7163930B2/en not_active Expired - Lifetime
-
2009
- 2009-07-21 JP JP2009170270A patent/JP2009280597A/ja not_active Withdrawn
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