JP2005508846A5 - - Google Patents
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- Publication number
- JP2005508846A5 JP2005508846A5 JP2002578964A JP2002578964A JP2005508846A5 JP 2005508846 A5 JP2005508846 A5 JP 2005508846A5 JP 2002578964 A JP2002578964 A JP 2002578964A JP 2002578964 A JP2002578964 A JP 2002578964A JP 2005508846 A5 JP2005508846 A5 JP 2005508846A5
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- free
- formula
- compound
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- -1 4-pyrazinyl Chemical group 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 9
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 6
- 125000004432 carbon atom Chemical group C* 0.000 claims 5
- 125000001931 aliphatic group Chemical group 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 125000004043 oxo group Chemical group O=* 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 125000005277 alkyl imino group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000001589 carboacyl group Chemical group 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000001841 imino group Chemical group [H]N=* 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 125000002757 morpholinyl group Chemical class 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 125000003386 piperidinyl group Chemical class 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 125000004076 pyridyl group Chemical class 0.000 claims 2
- 125000000719 pyrrolidinyl group Chemical class 0.000 claims 2
- 125000000446 sulfanediyl group Chemical group *S* 0.000 claims 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 2
- 150000004046 2-(N-anilino)pyrimidines Chemical class 0.000 claims 1
- 208000028185 Angioedema Diseases 0.000 claims 1
- 206010006473 Bronchopulmonary aspergillosis Diseases 0.000 claims 1
- 241000282465 Canis Species 0.000 claims 1
- 241000282472 Canis lupus familiaris Species 0.000 claims 1
- 206010012434 Dermatitis allergic Diseases 0.000 claims 1
- 206010013700 Drug hypersensitivity Diseases 0.000 claims 1
- 208000004262 Food Hypersensitivity Diseases 0.000 claims 1
- 206010016946 Food allergy Diseases 0.000 claims 1
- 208000004430 Pulmonary Aspergillosis Diseases 0.000 claims 1
- 206010039085 Rhinitis allergic Diseases 0.000 claims 1
- 208000034972 Sudden Infant Death Diseases 0.000 claims 1
- 206010042440 Sudden infant death syndrome Diseases 0.000 claims 1
- 208000024780 Urticaria Diseases 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 201000010105 allergic rhinitis Diseases 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 201000005311 drug allergy Diseases 0.000 claims 1
- 235000020932 food allergy Nutrition 0.000 claims 1
- 125000002883 imidazolyl group Chemical group 0.000 claims 1
- 125000001041 indolyl group Chemical group 0.000 claims 1
- 201000006512 mast cell neoplasm Diseases 0.000 claims 1
- 208000008585 mastocytosis Diseases 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2002/010742 WO2002080925A1 (en) | 2001-04-05 | 2002-04-05 | Use of n-phenyl-2-pyrimidineamine derivativea against mast cell-based diseases like allergic disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005508846A JP2005508846A (ja) | 2005-04-07 |
| JP2005508846A5 true JP2005508846A5 (enExample) | 2005-12-22 |
Family
ID=34465034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002578964A Pending JP2005508846A (ja) | 2002-04-05 | 2002-04-05 | アレルギー性疾患のような肥満細胞系疾患に対するｎ−フェニル−２−ピリミジンアミン誘導体の使用 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2005508846A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5129123B2 (ja) * | 2005-05-02 | 2013-01-23 | ノバルティス アーゲー | 全身性肥満細胞症の処置のためのピリミジルアミノベンズアミド誘導体の使用 |
-
2002
- 2002-04-05 JP JP2002578964A patent/JP2005508846A/ja active Pending
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