JP2005508613A - 潜伏中に発現されるマイコバクテリア抗原 - Google Patents

潜伏中に発現されるマイコバクテリア抗原 Download PDF

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Publication number
JP2005508613A
JP2005508613A JP2003510686A JP2003510686A JP2005508613A JP 2005508613 A JP2005508613 A JP 2005508613A JP 2003510686 A JP2003510686 A JP 2003510686A JP 2003510686 A JP2003510686 A JP 2003510686A JP 2005508613 A JP2005508613 A JP 2005508613A
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JP
Japan
Prior art keywords
mycobacteria
tuberculosis
gene
peptide
nutrient
Prior art date
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Pending
Application number
JP2003510686A
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English (en)
Japanese (ja)
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JP2005508613A5 (enExample
Inventor
ウィリアム ジェイムズ，ブライアン
マーシュ，フィリップ
ハンプシャー，トバイアス
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Public Health England
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Health Protection Agency
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Filing date
Publication date
Priority claimed from GB0116385A external-priority patent/GB0116385D0/en
Priority claimed from GB0123993A external-priority patent/GB0123993D0/en
Application filed by Health Protection Agency filed Critical Health Protection Agency
Publication of JP2005508613A publication Critical patent/JP2005508613A/ja
Publication of JP2005508613A5 publication Critical patent/JP2005508613A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003510686A 2001-07-04 2002-07-04 潜伏中に発現されるマイコバクテリア抗原 Pending JP2005508613A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0116385A GB0116385D0 (en) 2001-07-04 2001-07-04 Mycobacterial antigens expressed during latency
GB0123993A GB0123993D0 (en) 2001-10-05 2001-10-05 Mycobacterial antigens expressed during latency
PCT/GB2002/003052 WO2003004520A2 (en) 2001-07-04 2002-07-04 Mycobacterial antigens expressed during latency

Publications (2)

Publication Number Publication Date
JP2005508613A true JP2005508613A (ja) 2005-04-07
JP2005508613A5 JP2005508613A5 (enExample) 2005-12-22

Family

ID=26246282

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003510686A Pending JP2005508613A (ja) 2001-07-04 2002-07-04 潜伏中に発現されるマイコバクテリア抗原

Country Status (6)

Country Link
US (3) US7393540B2 (enExample)
EP (2) EP2196473A1 (enExample)
JP (1) JP2005508613A (enExample)
AU (2) AU2002314358C1 (enExample)
CA (1) CA2453173C (enExample)
WO (1) WO2003004520A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543890A (ja) * 2005-06-23 2008-12-04 ステイテンス・セラム・インスティテュート 改良された結核ワクチン
JP2014531896A (ja) * 2011-08-30 2014-12-04 ザ ユーエービー リサーチ ファンデーション ヒト型結核菌ポリンおよび毒素ならびに関連方法
JP2017526742A (ja) * 2014-08-15 2017-09-14 オックスフォード イミュノテック リミテッド 結核菌（Ｍｙｃｏｂａｃｔｅｒｉｕｍ ｔｕｂｅｒｃｕｌｏｓｉｓ）タンパク質
US12234464B2 (en) 2018-11-09 2025-02-25 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides

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GB9806093D0 (en) * 1998-03-20 1998-05-20 Taylor John Hermon Diagnostics and vaccines for mycobacterial infections of animals and humans
US7393539B2 (en) 2001-06-22 2008-07-01 Health Protection Agency Mycobacterial antigens expressed under low oxygen tension
EP2196473A1 (en) 2001-07-04 2010-06-16 Health Protection Agency Mycobacterial antigens expressed during latency
GB0125535D0 (en) * 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency
EP1523331B1 (en) * 2002-07-13 2013-02-27 Statens Serum Institut Therapeutic tb vaccine
WO2004067718A2 (en) * 2003-01-24 2004-08-12 Emory University Necrosis-deficient mutants of tuberculosis bacteria
ES2231037B1 (es) 2003-10-31 2005-12-16 Archivel Technologies, Sl Agente inmunoterapico util para el tratamiento combinado de la tuberculosis en asociacion con otros farmacos.
WO2006104389A1 (en) * 2005-03-31 2006-10-05 Leiden University Medical Center Methods and means for diagnostics, prevention and treatment of mycobacterium infections and tuberculosis disease
CA2606962A1 (en) * 2005-04-29 2006-11-09 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
EP1910410B1 (en) 2005-07-01 2011-10-26 Forsyth Dental Infirmary for Children Tuberculosis antigen detection assays and vaccines
EP1913020B1 (en) * 2005-08-09 2010-05-05 HAV Vaccines Limited Immunogenic constructs
US7601357B2 (en) * 2005-12-07 2009-10-13 University Of Central Florida Research Foundation, Inc. Targeting of long chain triacylglycerol hydrolase gene for tuberculosis treatment
CN101374964B (zh) * 2005-12-09 2013-07-17 贝勒研究院 外周血液白细胞转录模式的模块水平分析
NZ597557A (en) * 2006-03-02 2013-10-25 Uab Research Foundation Mycobacterial disease detection, treatment, and drug discovery
ES2307402B1 (es) 2006-10-30 2009-09-30 Archivel Farma, S.L. Vacuna profilactica contra la tuberculosis.
MX2010014556A (es) * 2008-06-25 2011-07-28 Baylor Res Inst Firma transcripcional de sangre por infeccion de mycobacterium tuberculosis.
US20110129817A1 (en) * 2009-11-30 2011-06-02 Baylor Research Institute Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection
US20100015171A1 (en) 2008-07-15 2010-01-21 Statens Serum Institute Vaccines comprising tb 10.4
ES2335177B1 (es) 2008-09-19 2011-02-28 Archivel Farma, S.L. Agente inmunoterapeutico apropiado para la profilaxis primaria de la tuberculosis.
CN102713629B (zh) 2009-11-20 2016-02-24 俄勒冈健康科学大学 用于检测结核分枝杆菌感染的方法
GB201008512D0 (en) * 2010-05-21 2010-07-07 Health Prot Agency Mycobacterial antigen composition
ITRM20100411A1 (it) * 2010-07-23 2012-01-24 Massimo Amicosante Uso di sequenze amminoacidiche da mycobacterium tuberculosis o dei loro corrispondenti acidi nucleici per la diagnosi e la prevenzione di infezione tubercolare, relativo kit diagnostico e vaccino.
PL2661253T3 (pl) 2011-01-04 2017-08-31 Archivel Farma, Sl Preparat liposomowy odpowiedni do leczenia lub zapobiegania gruźlicy
EP2471511A1 (en) 2011-01-04 2012-07-04 Archivel Farma, SL Liposome formulation suitable for treating or preventing tuberculosis
WO2012138754A2 (en) * 2011-04-04 2012-10-11 Beth Israel Deaconess Medical Center, Inc. Mycobacterial vaccine vectors and methods of using the same
US10703784B2 (en) * 2011-09-30 2020-07-07 La Jolla Institute For Allergy And Immunology Antigens and epitopes derived from Mycobacterium tuberculosis
US20140349320A1 (en) * 2011-12-15 2014-11-27 The Trustees Of The University Of Pennsylvania Using Adaptive Immunity to Detect Drug Resistance
US10357555B2 (en) 2012-07-10 2019-07-23 Transgene Sa Mycobacterial antigen vaccine
US10197560B2 (en) 2013-06-27 2019-02-05 The Brigham And Women's Hospital, Inc. Methods and systems for determining M. tuberculosis infection
RU2695462C2 (ru) 2014-01-09 2019-07-23 Трансген Са Гибридизация гетероолигомерных микобактериальных антигенов
GB201400819D0 (en) * 2014-01-17 2014-03-05 Sec Dep For Health The Mycobacterial antigen composition
CN108267588B (zh) * 2016-12-30 2020-10-23 首都医科大学附属北京胸科医院 结核分枝杆菌蛋白在制备诊断结核潜伏感染者和/或活动性肺结核产品中的用途
CN110129465B (zh) * 2019-05-22 2023-08-22 杭州优思达生物技术股份有限公司 一种海分枝杆菌核酸的快速检测方法及其试剂盒

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US6892139B2 (en) * 1999-01-29 2005-05-10 The Regents Of The University Of California Determining the functions and interactions of proteins by comparative analysis
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US7393539B2 (en) * 2001-06-22 2008-07-01 Health Protection Agency Mycobacterial antigens expressed under low oxygen tension
EP2196473A1 (en) * 2001-07-04 2010-06-16 Health Protection Agency Mycobacterial antigens expressed during latency
GB0125535D0 (en) 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543890A (ja) * 2005-06-23 2008-12-04 ステイテンス・セラム・インスティテュート 改良された結核ワクチン
JP2013121959A (ja) * 2005-06-23 2013-06-20 Statens Serum Inst 改良された結核ワクチン
JP2014531896A (ja) * 2011-08-30 2014-12-04 ザ ユーエービー リサーチ ファンデーション ヒト型結核菌ポリンおよび毒素ならびに関連方法
JP2017526742A (ja) * 2014-08-15 2017-09-14 オックスフォード イミュノテック リミテッド 結核菌（Ｍｙｃｏｂａｃｔｅｒｉｕｍ ｔｕｂｅｒｃｕｌｏｓｉｓ）タンパク質
JP2020198886A (ja) * 2014-08-15 2020-12-17 オックスフォード イミュノテック リミテッド 結核菌（Ｍｙｃｏｂａｃｔｅｒｉｕｍ ｔｕｂｅｒｃｕｌｏｓｉｓ）タンパク質
US12234464B2 (en) 2018-11-09 2025-02-25 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides

Also Published As

Publication number Publication date
US20090082296A1 (en) 2009-03-26
AU2002314358B2 (en) 2008-08-14
US7393540B2 (en) 2008-07-01
CA2453173C (en) 2013-12-10
US20040241826A1 (en) 2004-12-02
EP2196473A1 (en) 2010-06-16
AU2002314358C1 (en) 2009-03-26
AU2008243118A1 (en) 2008-11-27
EP1404706A2 (en) 2004-04-07
WO2003004520A3 (en) 2003-10-16
US8003776B2 (en) 2011-08-23
WO2003004520A2 (en) 2003-01-16
US20120034689A1 (en) 2012-02-09
US8399650B2 (en) 2013-03-19
CA2453173A1 (en) 2003-01-16

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