JP2005503113A5 - - Google Patents
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- Publication number
- JP2005503113A5 JP2005503113A5 JP2002562749A JP2002562749A JP2005503113A5 JP 2005503113 A5 JP2005503113 A5 JP 2005503113A5 JP 2002562749 A JP2002562749 A JP 2002562749A JP 2002562749 A JP2002562749 A JP 2002562749A JP 2005503113 A5 JP2005503113 A5 JP 2005503113A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- pollen
- protein
- antibody
- allergen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 108090000623 proteins and genes Proteins 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 12
- 239000013573 pollen allergen Substances 0.000 claims 10
- 239000013566 allergen Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
- 230000001225 therapeutic effect Effects 0.000 claims 5
- 239000009342 ragweed pollen Substances 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000008346 aqueous phase Substances 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 238000004587 chromatography analysis Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 239000000284 extract Substances 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000002244 precipitate Substances 0.000 claims 2
- 238000002331 protein detection Methods 0.000 claims 2
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 claims 2
- 239000006228 supernatant Substances 0.000 claims 2
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 claims 1
- 244000036975 Ambrosia artemisiifolia Species 0.000 claims 1
- 235000003129 Ambrosia artemisiifolia var elatior Nutrition 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 206010048908 Seasonal allergy Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 238000001042 affinity chromatography Methods 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 235000003484 annual ragweed Nutrition 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 235000006263 bur ragweed Nutrition 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 235000003488 common ragweed Nutrition 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000001962 electrophoresis Methods 0.000 claims 1
- 238000001641 gel filtration chromatography Methods 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000012074 organic phase Substances 0.000 claims 1
- 239000003208 petroleum Substances 0.000 claims 1
- 201000004338 pollen allergy Diseases 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- 230000006920 protein precipitation Effects 0.000 claims 1
- 235000009736 ragweed Nutrition 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26668601P | 2001-02-05 | 2001-02-05 | |
| PCT/US2002/003346 WO2002063012A2 (en) | 2001-02-05 | 2002-02-04 | Ragweed allergens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005503113A JP2005503113A (ja) | 2005-02-03 |
| JP2005503113A5 true JP2005503113A5 (enExample) | 2005-12-22 |
Family
ID=23015588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002562749A Withdrawn JP2005503113A (ja) | 2001-02-05 | 2002-02-04 | ブタクサアレルゲン |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20030180225A1 (enExample) |
| EP (1) | EP1360297A2 (enExample) |
| JP (1) | JP2005503113A (enExample) |
| CA (1) | CA2437484A1 (enExample) |
| WO (1) | WO2002063012A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030180225A1 (en) * | 2001-02-05 | 2003-09-25 | Buchanan Bob B. | Walnut and ryegrass allergens |
| CN101988925B (zh) * | 2009-08-06 | 2013-05-08 | 中国医学科学院北京协和医院 | 用于检测Hum j 3特异性IgE抗体的ELISA试剂盒 |
| EP2533808B1 (en) * | 2010-02-12 | 2014-08-20 | Laboratorios LETI, S.L. | Process for producing an allergen extract |
| JP6411034B2 (ja) * | 2013-06-06 | 2018-10-24 | 三栄源エフ・エフ・アイ株式会社 | 天然酸性色素中のタンパク質の分析方法 |
| CN109939227B (zh) * | 2018-03-23 | 2023-04-28 | 中国医学科学院北京协和医院 | 一种豚草花粉变应原浸提物、其浸液及其制备方法 |
| CN113599514B (zh) * | 2021-06-25 | 2023-03-17 | 广州医科大学附属第一医院（广州呼吸中心） | 一种用于比格犬哮喘模型造模的组合物和哮喘模型造模方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3148122A (en) * | 1960-01-27 | 1964-09-08 | Miles Lab | Water-insoluble whole pollen complex and method of making same |
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| NL8900652A (nl) * | 1989-03-16 | 1990-10-16 | Leti Lab | Primair-toxische stoffen of allergenen, isoleerbaar uit plantaardig materiaal, alsmede werkwijzen ter bereiding ervan en de toepassing ervan. |
| US5776761A (en) * | 1989-03-17 | 1998-07-07 | Immulogic Pharmaceutical Corporation | Nucleic acids encoding allergenic proteins from ragweed |
| DE4023945A1 (de) * | 1990-07-27 | 1992-01-30 | Progen Biotechnik Gmbh | Verfahren zur reinigung von cytokeratin 20 und dessen verwendung zur erzeugung von antikoerpern |
| US6555116B1 (en) * | 1991-10-12 | 2003-04-29 | Regents Of The University Of California | Alleviation of the allergenic potential of airborne and contact allergens by thioredoxin |
| US5480972A (en) * | 1992-10-30 | 1996-01-02 | The University Of Melbourne | Allergenic proteins from Johnson grass pollen |
| US20040092446A1 (en) * | 1997-07-23 | 2004-05-13 | Goulmy Elsa A.J.M. | HA-1 epitopes and uses thereof |
| US20030180225A1 (en) * | 2001-02-05 | 2003-09-25 | Buchanan Bob B. | Walnut and ryegrass allergens |
-
2002
- 2002-02-04 US US10/067,620 patent/US20030180225A1/en not_active Abandoned
- 2002-02-04 EP EP02717392A patent/EP1360297A2/en not_active Withdrawn
- 2002-02-04 WO PCT/US2002/003346 patent/WO2002063012A2/en not_active Ceased
- 2002-02-04 JP JP2002562749A patent/JP2005503113A/ja not_active Withdrawn
- 2002-02-04 CA CA002437484A patent/CA2437484A1/en not_active Abandoned
- 2002-02-04 US US10/067,484 patent/US20030170763A1/en not_active Abandoned
-
2005
- 2005-09-26 US US11/236,012 patent/US20060099215A1/en not_active Abandoned
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