JP2005502319A5 - - Google Patents
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- Publication number
- JP2005502319A5 JP2005502319A5 JP2002579898A JP2002579898A JP2005502319A5 JP 2005502319 A5 JP2005502319 A5 JP 2005502319A5 JP 2002579898 A JP2002579898 A JP 2002579898A JP 2002579898 A JP2002579898 A JP 2002579898A JP 2005502319 A5 JP2005502319 A5 JP 2005502319A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- polypeptide
- dna
- fragment
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 claims 5
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 230000002207 retinal effect Effects 0.000 claims 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000003223 protective agent Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000032578 Inherited retinal disease Diseases 0.000 claims 1
- 208000032430 Retinal dystrophy Diseases 0.000 claims 1
- 201000006321 fundus dystrophy Diseases 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 208000017532 inherited retinal dystrophy Diseases 0.000 claims 1
- 230000004083 survival effect Effects 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
Images
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0104712A FR2823221B1 (fr) | 2001-04-06 | 2001-04-06 | Sequences associees a la degenerescence retinienne et applications |
| PCT/EP2002/003810 WO2002081513A2 (en) | 2001-04-06 | 2002-04-05 | Disease-associated protein |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009050689A Division JP4571695B2 (ja) | 2001-04-06 | 2009-03-04 | 疾患関連タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005502319A JP2005502319A (ja) | 2005-01-27 |
| JP2005502319A5 true JP2005502319A5 (enExample) | 2009-06-18 |
| JP4370428B2 JP4370428B2 (ja) | 2009-11-25 |
Family
ID=8862037
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002579898A Expired - Lifetime JP4370428B2 (ja) | 2001-04-06 | 2002-04-05 | 疾患関連タンパク質 |
| JP2009050689A Expired - Lifetime JP4571695B2 (ja) | 2001-04-06 | 2009-03-04 | 疾患関連タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009050689A Expired - Lifetime JP4571695B2 (ja) | 2001-04-06 | 2009-03-04 | 疾患関連タンパク質 |
Country Status (22)
| Country | Link |
|---|---|
| US (6) | US7795387B2 (enExample) |
| EP (1) | EP1379657B1 (enExample) |
| JP (2) | JP4370428B2 (enExample) |
| KR (1) | KR100913258B1 (enExample) |
| CN (1) | CN1529753B (enExample) |
| AU (1) | AU2002312794B8 (enExample) |
| BR (1) | BRPI0208870B8 (enExample) |
| CA (1) | CA2443345C (enExample) |
| CZ (1) | CZ305800B6 (enExample) |
| EC (1) | ECSP024345A (enExample) |
| ES (1) | ES2597835T3 (enExample) |
| FR (1) | FR2823221B1 (enExample) |
| HU (1) | HU226307B1 (enExample) |
| IL (3) | IL158013A0 (enExample) |
| MX (1) | MXPA03009114A (enExample) |
| NO (1) | NO331277B1 (enExample) |
| NZ (1) | NZ528376A (enExample) |
| PL (1) | PL213658B1 (enExample) |
| RU (1) | RU2384586C2 (enExample) |
| SK (1) | SK288465B6 (enExample) |
| WO (1) | WO2002081513A2 (enExample) |
| ZA (1) | ZA200307403B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2823221B1 (fr) | 2001-04-06 | 2004-04-02 | Univ Pasteur | Sequences associees a la degenerescence retinienne et applications |
| PT1625210E (pt) | 2003-05-21 | 2011-03-15 | Genzyme Corp | Métodos para produzir preparações de vírions de aav recombinantes substancialmente livres de capsídeos vazios |
| FR2870241B1 (fr) * | 2004-05-13 | 2015-02-27 | Novartis Ag | Facteur de viabilite des cones derive des batonnets ou rdcvf et applications |
| EP2027889A1 (en) * | 2007-06-05 | 2009-02-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | New neuronal viability factor and use thereof |
| WO2009146183A1 (en) * | 2008-04-15 | 2009-12-03 | Genzyme Corporation | Methods to produce rod-derived cone viability factor (rdcvf) |
| WO2010029130A1 (en) * | 2008-09-10 | 2010-03-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Neuronal viability factor and use thereof |
| EP2383286A1 (en) | 2010-04-30 | 2011-11-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treatment of retinal degenerative diseases |
| DK2797613T3 (da) | 2011-10-27 | 2020-03-02 | Wellstat Ophthalmics Corp | Vektorer, der koder for rod-derived cone viability-faktor |
| US20150038557A1 (en) | 2012-02-24 | 2015-02-05 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treatment of retinal degenerative diseases |
| WO2014060517A1 (en) * | 2012-10-17 | 2014-04-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of age-related macular degeneration (amd) |
| PL3412684T3 (pl) | 2013-07-31 | 2022-08-08 | Novartis Ag | Nowe wektory selekcyjne i sposoby selekcji eukariotycznych komórek gospodarzy |
| JP6684343B2 (ja) | 2015-05-21 | 2020-04-22 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | ニューロン生存因子の相乗組み合わせ及びその使用 |
| WO2017120294A1 (en) | 2016-01-05 | 2017-07-13 | The Trustees Of The University Of Pennsylvania | Methods and compositions for treatment of ocular disorders and blinding diseases |
| GB201603987D0 (en) | 2016-03-08 | 2016-04-20 | Immatics Biotechnologies Gmbh | Uterine cancer treatments |
| US10946063B2 (en) | 2016-10-11 | 2021-03-16 | Welltat Ophthalmics Corporation | Fusion protein between short form rod-derived cone viability factor and a hydrophilic peptide |
| JP7495756B2 (ja) * | 2019-12-09 | 2024-06-05 | 北京中因科技有限公司 | 医薬の製造におけるＣＹＰ４Ｖ２およびＲｄＣＶＦの使用 |
| CN111733174B (zh) * | 2020-08-07 | 2021-02-09 | 北京大学第三医院（北京大学第三临床医学院） | 一种分离的核酸分子及其用途 |
| US20250276088A1 (en) * | 2021-07-07 | 2025-09-04 | Institut National de la Santé et de la Recherche Médicale | Synergistic combination of rdcfv2 and rdcvf2l for the treatment of tauopathies |
| CN113774019B (zh) * | 2021-08-11 | 2024-02-13 | 东南大学 | 一种脐带血间充质干细胞无血清培养基、培养方法及其应用 |
| WO2024206928A1 (en) | 2023-03-30 | 2024-10-03 | Pharma Cinq, Llc | VECTOR ENCODING ROD-DERIVED CONE VIABILITY FACTOR AND HUMAN IgK SIGNAL SEQUENCE |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4771036A (en) * | 1986-02-10 | 1988-09-13 | Trustees Of Columbia University In The City Of New York | Method and ophthalmic composition for the prevention and reversal of cataracts |
| GB9701710D0 (en) | 1997-01-28 | 1997-03-19 | Karobio Ab | Mammalian protein |
| US6106825A (en) * | 1997-05-07 | 2000-08-22 | University Of Florida | Entomopoxvirus-vertebrate gene delivery vector and method |
| FR2784030B1 (fr) * | 1998-10-02 | 2002-12-20 | Inst Nat Sante Rech Med | Utilisation de bloqueurs des canaux calciques et/ou cgmp-dependants pour le traitement de pathologies de la retine |
| FR2784898A1 (fr) * | 1998-10-26 | 2000-04-28 | Univ Pasteur | Utilisation du gdnf pour le traitement de la degenerescence retinienne |
| EP1033405A3 (en) * | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
| WO2001053312A1 (en) * | 1999-12-23 | 2001-07-26 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| FR2823221B1 (fr) | 2001-04-06 | 2004-04-02 | Univ Pasteur | Sequences associees a la degenerescence retinienne et applications |
| US20060275794A1 (en) | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
| WO2010029130A1 (en) | 2008-09-10 | 2010-03-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Neuronal viability factor and use thereof |
-
2001
- 2001-04-06 FR FR0104712A patent/FR2823221B1/fr not_active Expired - Lifetime
-
2002
- 2002-04-05 WO PCT/EP2002/003810 patent/WO2002081513A2/en not_active Ceased
- 2002-04-05 JP JP2002579898A patent/JP4370428B2/ja not_active Expired - Lifetime
- 2002-04-05 KR KR1020037012934A patent/KR100913258B1/ko not_active Expired - Lifetime
- 2002-04-05 HU HU0303730A patent/HU226307B1/hu unknown
- 2002-04-05 US US10/473,008 patent/US7795387B2/en not_active Expired - Lifetime
- 2002-04-05 CA CA2443345A patent/CA2443345C/en not_active Expired - Lifetime
- 2002-04-05 AU AU2002312794A patent/AU2002312794B8/en not_active Expired
- 2002-04-05 NZ NZ528376A patent/NZ528376A/en not_active IP Right Cessation
- 2002-04-05 CZ CZ2003-2706A patent/CZ305800B6/cs not_active IP Right Cessation
- 2002-04-05 MX MXPA03009114A patent/MXPA03009114A/es active IP Right Grant
- 2002-04-05 RU RU2003130638/13A patent/RU2384586C2/ru active
- 2002-04-05 ES ES02737923.9T patent/ES2597835T3/es not_active Expired - Lifetime
- 2002-04-05 IL IL15801302A patent/IL158013A0/xx unknown
- 2002-04-05 EP EP02737923.9A patent/EP1379657B1/en not_active Expired - Lifetime
- 2002-04-05 PL PL364681A patent/PL213658B1/pl unknown
- 2002-04-05 CN CN028094700A patent/CN1529753B/zh not_active Expired - Lifetime
- 2002-04-05 BR BRPI0208870A patent/BRPI0208870B8/pt not_active IP Right Cessation
- 2002-04-05 SK SK1223-2003A patent/SK288465B6/sk unknown
- 2002-11-19 EC EC2002004345A patent/ECSP024345A/es unknown
-
2003
- 2003-09-18 IL IL158013A patent/IL158013A/en unknown
- 2003-09-23 ZA ZA200307403A patent/ZA200307403B/en unknown
- 2003-10-03 NO NO20034452A patent/NO331277B1/no not_active IP Right Cessation
-
2007
- 2007-04-25 US US11/739,734 patent/US8071745B2/en not_active Expired - Fee Related
- 2007-04-25 US US11/739,739 patent/US8114849B2/en not_active Expired - Fee Related
-
2009
- 2009-03-04 JP JP2009050689A patent/JP4571695B2/ja not_active Expired - Lifetime
- 2009-06-11 IL IL199316A patent/IL199316A/en active IP Right Grant
-
2012
- 2012-01-11 US US13/348,435 patent/US8518695B2/en not_active Expired - Fee Related
- 2012-01-11 US US13/348,383 patent/US8394756B2/en not_active Expired - Fee Related
-
2013
- 2013-06-04 US US13/909,764 patent/US8957043B2/en not_active Expired - Fee Related
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