JP2005247873A5 - - Google Patents
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- Publication number
- JP2005247873A5 JP2005247873A5 JP2005159852A JP2005159852A JP2005247873A5 JP 2005247873 A5 JP2005247873 A5 JP 2005247873A5 JP 2005159852 A JP2005159852 A JP 2005159852A JP 2005159852 A JP2005159852 A JP 2005159852A JP 2005247873 A5 JP2005247873 A5 JP 2005247873A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- hydroxy
- diphosphonic acid
- bisphosphonate
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59713500A | 2000-06-20 | 2000-06-20 | |
| US09/597,135 | 2000-06-20 | ||
| US26768901P | 2001-02-09 | 2001-02-09 | |
| US60/267,689 | 2001-02-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002503265A Division JP4722375B2 (ja) | 2000-06-20 | 2001-06-18 | ビホスホネートの投与法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005247873A JP2005247873A (ja) | 2005-09-15 |
| JP2005247873A5 true JP2005247873A5 (https=) | 2008-07-17 |
| JP5005188B2 JP5005188B2 (ja) | 2012-08-22 |
Family
ID=26952565
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002503265A Expired - Lifetime JP4722375B2 (ja) | 2000-06-20 | 2001-06-18 | ビホスホネートの投与法 |
| JP2005159852A Expired - Lifetime JP5005188B2 (ja) | 2000-06-20 | 2005-05-31 | ビホスホネートの投与法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002503265A Expired - Lifetime JP4722375B2 (ja) | 2000-06-20 | 2001-06-18 | ビホスホネートの投与法 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8052987B2 (https=) |
| EP (1) | EP1296689B3 (https=) |
| JP (2) | JP4722375B2 (https=) |
| KR (1) | KR100864743B1 (https=) |
| CN (1) | CN1272013C (https=) |
| AT (1) | ATE304856T1 (https=) |
| AU (2) | AU7410901A (https=) |
| BR (1) | BR0111806A (https=) |
| CA (1) | CA2410201C (https=) |
| CY (2) | CY1113740T1 (https=) |
| CZ (1) | CZ301972B6 (https=) |
| DE (1) | DE60113537T3 (https=) |
| DK (1) | DK1296689T3 (https=) |
| ES (2) | ES2394211T3 (https=) |
| HU (1) | HU228400B1 (https=) |
| IL (2) | IL153229A0 (https=) |
| MX (1) | MXPA02012682A (https=) |
| NO (1) | NO330459B1 (https=) |
| NZ (1) | NZ523086A (https=) |
| PL (1) | PL203087B1 (https=) |
| PT (1) | PT1591122E (https=) |
| SK (1) | SK287278B6 (https=) |
| TW (1) | TWI289451B (https=) |
| WO (1) | WO2001097788A2 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8119159B2 (en) * | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
| US7658938B2 (en) * | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
| US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
| ES2394211T3 (es) | 2000-06-20 | 2013-01-23 | Novartis Ag | Procedimiento de administración de bifosfonatos |
| EP1192945A3 (en) * | 2000-09-21 | 2004-03-03 | Pfizer Products Inc. | Use of an estrogen agonist/antagonist for treating osteoarthritis |
| EP1383509A4 (en) * | 2001-04-03 | 2005-10-26 | Royal Alexandra Hosp Children | MEDICAMENT FOR USE IN BONE TRAINING |
| US20050070504A1 (en) * | 2001-12-21 | 2005-03-31 | The Procter & Gamble Co. | Risedronate compositions and their methods of use |
| GB0204756D0 (en) * | 2002-02-28 | 2002-04-17 | Novartis Ag | Organic compounds |
| KR20060058151A (ko) * | 2002-05-10 | 2006-05-29 | 에프. 호프만-라 로슈 아게 | 골다공증 치료 및 예방용 비스포스폰산 |
| AU2003270196A1 (en) * | 2002-09-16 | 2004-04-30 | Kenneth W. Lyles | Method for preventing or reducing secondary fractures after hip fracture |
| CN1705485A (zh) * | 2002-10-15 | 2005-12-07 | 诺瓦提斯公司 | 施用双膦酸类化合物的方法 |
| ES2291749T5 (es) | 2002-12-20 | 2011-07-21 | F. Hoffmann-La Roche Ag | Formulación de altas dosis de ibandronato. |
| JPWO2005072746A1 (ja) * | 2004-01-30 | 2007-10-11 | アステラス製薬株式会社 | P2x受容体阻害剤 |
| EP1713489B1 (en) * | 2004-08-23 | 2011-01-19 | Teva Pharmaceutical Industries Ltd | Crystalline form of ibandronate sodium and processes for preparation thereof |
| US7709508B2 (en) | 2004-12-09 | 2010-05-04 | Merck Sharp & Dohme | Estrogen receptor modulators |
| NZ555316A (en) * | 2004-12-09 | 2009-08-28 | Merck & Co Inc | Estrogen receptor modulators |
| US8071574B2 (en) * | 2005-02-22 | 2011-12-06 | John Dennis Bobyn | Implant improving local bone formation |
| US7473684B2 (en) * | 2005-09-16 | 2009-01-06 | Selamine Limited | Bisphosphonate formulation |
| KR101191322B1 (ko) * | 2006-04-07 | 2012-10-16 | 메리온 리서치 Ⅲ 리미티드 | 증진제를 함유하는 고형 경구용 투여 제형 |
| US20090075941A1 (en) * | 2006-04-21 | 2009-03-19 | The Uab Research Foundation | Treating neoplasms |
| US20080139514A1 (en) * | 2006-11-29 | 2008-06-12 | Subhash Pandurang Gore | Diphosphonic acid pharmaceutical compositions |
| US20100068211A1 (en) * | 2008-02-08 | 2010-03-18 | Bateman Ted A | Use of antiresorptive compounds to prevent ionizing radiation-induced activation of osteoclasts and resulting bone loss |
| CN107096012A (zh) * | 2008-05-07 | 2017-08-29 | 诺和诺德股份有限公司 | 肽的组合物及其制备方法 |
| US20100215743A1 (en) * | 2009-02-25 | 2010-08-26 | Leonard Thomas W | Composition and drug delivery of bisphosphonates |
| DK2459176T3 (en) | 2009-07-31 | 2017-12-04 | Gruenenthal Gmbh | Crystallization process and bioavailability |
| US9169279B2 (en) | 2009-07-31 | 2015-10-27 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| CN105920023A (zh) | 2009-09-01 | 2016-09-07 | 杜克大学 | 双膦酸类组合物及其治疗心力衰竭的方法 |
| US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
| WO2011120033A1 (en) * | 2010-03-26 | 2011-09-29 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor xa inhibitors for oral administration |
| US9340565B2 (en) | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
| EP2661273A4 (en) | 2011-01-07 | 2014-06-04 | Merrion Res Iii Ltd | IRON PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION |
| CN104010647A (zh) | 2011-11-16 | 2014-08-27 | 杜克大学 | 用于治疗和/或减轻心功能障碍的双膦酸盐组合物及方法 |
| CN103623465B (zh) * | 2013-11-21 | 2015-12-30 | 彭江 | 一种可局部调节成破骨活性的组织工程骨支架及制备方法 |
| US10265384B2 (en) | 2015-01-29 | 2019-04-23 | Novo Nordisk A/S | Tablets comprising GLP-1 agonist and enteric coating |
| US10195218B2 (en) | 2016-05-31 | 2019-02-05 | Grunenthal Gmbh | Crystallization method and bioavailability |
| KR20180115979A (ko) * | 2017-04-14 | 2018-10-24 | 연세대학교 산학협력단 | 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물 |
| GB201716716D0 (en) | 2017-10-12 | 2017-11-29 | Univ Of Hertfordshire Higher Education Corporation | Method for coating particles |
| JP2022536222A (ja) * | 2018-11-02 | 2022-08-15 | アンパサンド バイオファーマシューティカルズ インコーポレイテッド | 局所的に施用される緩衝液によるカチオン過負荷および電解質平衡異常のリスクの管理 |
| KR102049233B1 (ko) * | 2019-01-14 | 2019-11-28 | 연세대학교 산학협력단 | 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US594329A (en) * | 1897-11-23 | Socket or collet | ||
| DE3232959A1 (de) | 1982-09-04 | 1984-03-08 | Hoechst Ag, 6230 Frankfurt | Substituierte benzolsulfonsaeureester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3583887D1 (de) | 1984-04-30 | 1991-10-02 | Procter & Gamble | Ausruestung fuer die behandlung der osteoporose. |
| US4822609A (en) | 1984-12-21 | 1989-04-18 | The Procter & Gamble Company | Treatment of osteoporosis |
| US4812304A (en) | 1984-12-21 | 1989-03-14 | The Procter & Gamble Company | Treatment of osteoporosis |
| US4812311A (en) | 1984-12-21 | 1989-03-14 | The Procter & Gamble Company | Kit for use in the treatment of osteoporosis |
| US4761406A (en) | 1985-06-06 | 1988-08-02 | The Procter & Gamble Company | Regimen for treating osteoporosis |
| ES2038692T4 (es) | 1986-11-21 | 2012-02-10 | Novartis Ag | Procedimiento para la obtencion de acidos alcanodifosfonicos substituidos. |
| JPH07502507A (ja) | 1991-12-17 | 1995-03-16 | プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド | ビスホスホネート類及び副甲状腺ホルモンを用いた骨粗鬆症の治療方法 |
| DK0648120T3 (da) | 1992-06-30 | 1998-01-19 | Procter & Gamble Pharma | Anvendelse af phosphonater til behandling af osteoporose |
| AU670337B2 (en) | 1992-11-30 | 1996-07-11 | Novartis Ag | Use of certain methanebisphosphonic acid derivatives in fracture healing |
| EP0600834A1 (en) | 1992-11-30 | 1994-06-08 | Ciba-Geigy Ag | Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing |
| US5366965A (en) | 1993-01-29 | 1994-11-22 | Boehringer Mannheim Gmbh | Regimen for treatment or prophylaxis of osteoporosis |
| GB9408775D0 (en) | 1994-05-04 | 1994-06-22 | Ciba Geigy Ag | Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration |
| KR970705399A (ko) | 1994-09-09 | 1997-10-09 | 레이셔 야코버스 코넬리스 | 골다공증용 포스포네이트 및 부갑상성 호르몬(phosphonates and parathyroid hormone for osteoporosis) |
| WO1996007417A1 (en) | 1994-09-09 | 1996-03-14 | The Procter & Gamble Company | Methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone |
| ATE290871T1 (de) | 1995-09-29 | 2005-04-15 | Novartis Pharma Gmbh | Verfahren zur behandlung navikularer krankheiten bei pferden |
| US5735810A (en) | 1996-06-14 | 1998-04-07 | Becton Dickinson And Company | Device for the iontophoretic administration of bisphosphonates |
| US5730715A (en) | 1996-06-14 | 1998-03-24 | Becton Dickinson And Company | Method for the iontophoretic administration of bisphosphonates |
| SE9702401D0 (sv) | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
| US6432932B1 (en) | 1997-07-22 | 2002-08-13 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| US6015801A (en) * | 1997-07-22 | 2000-01-18 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| US5994329A (en) | 1997-07-22 | 1999-11-30 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| PT1175904E (pt) | 1997-07-22 | 2007-04-30 | Merck & Co Inc | Alendronato para utilização no tratamento da osteoporose |
| FI109088B (fi) | 1997-09-19 | 2002-05-31 | Leiras Oy | Tabletti ja menetelmä sen valmistamiseksi |
| SE9703691D0 (sv) * | 1997-10-10 | 1997-10-10 | Astra Ab | Pharmaceutical compositions |
| IT1296495B1 (it) | 1997-11-21 | 1999-06-25 | Prodotti Antibiotici Spa | Impiego di bisfosfonati nella preparazione di forme farmaceutiche per somministrazione intramuscolare |
| GB2336311A (en) | 1998-04-15 | 1999-10-20 | Merck & Co Inc | Bisphosphonate Dosing Regimen |
| CA2308532C (en) | 1999-05-12 | 2005-11-29 | Gador S.A. | Use of bisphosphonates for the treatment of osteogenesis imperfecta |
| PL351674A1 (en) * | 1999-05-21 | 2003-05-19 | Novartis Ag | Use of bisphosphonic acids for treating angiogenesis |
| AU2270101A (en) | 1999-12-20 | 2001-07-03 | Merck & Co., Inc. | Pharmaceutical kit |
| GB0012209D0 (en) | 2000-05-19 | 2000-07-12 | Novartis Ag | Organic compounds |
| ES2394211T3 (es) | 2000-06-20 | 2013-01-23 | Novartis Ag | Procedimiento de administración de bifosfonatos |
-
2001
- 2001-06-18 ES ES05012711T patent/ES2394211T3/es not_active Expired - Lifetime
- 2001-06-18 BR BR0111806-4A patent/BR0111806A/pt not_active Application Discontinuation
- 2001-06-18 AT AT01940580T patent/ATE304856T1/de active
- 2001-06-18 KR KR1020027017283A patent/KR100864743B1/ko not_active Expired - Lifetime
- 2001-06-18 AU AU7410901A patent/AU7410901A/xx active Pending
- 2001-06-18 US US10/311,942 patent/US8052987B2/en not_active Expired - Lifetime
- 2001-06-18 NZ NZ523086A patent/NZ523086A/en not_active IP Right Cessation
- 2001-06-18 SK SK1808-2002A patent/SK287278B6/sk not_active IP Right Cessation
- 2001-06-18 EP EP01940580A patent/EP1296689B3/en not_active Expired - Lifetime
- 2001-06-18 JP JP2002503265A patent/JP4722375B2/ja not_active Expired - Lifetime
- 2001-06-18 AU AU2001274109A patent/AU2001274109B2/en not_active Expired
- 2001-06-18 CA CA2410201A patent/CA2410201C/en not_active Expired - Lifetime
- 2001-06-18 DK DK01940580T patent/DK1296689T3/da active
- 2001-06-18 DE DE60113537T patent/DE60113537T3/de not_active Expired - Lifetime
- 2001-06-18 CZ CZ20024134A patent/CZ301972B6/cs not_active IP Right Cessation
- 2001-06-18 CN CNB018113680A patent/CN1272013C/zh not_active Ceased
- 2001-06-18 IL IL15322901A patent/IL153229A0/xx active IP Right Review Request
- 2001-06-18 PL PL358224A patent/PL203087B1/pl unknown
- 2001-06-18 MX MXPA02012682A patent/MXPA02012682A/es active IP Right Grant
- 2001-06-18 PT PT50127117T patent/PT1591122E/pt unknown
- 2001-06-18 ES ES01940580T patent/ES2247123T7/es active Active
- 2001-06-18 WO PCT/EP2001/006850 patent/WO2001097788A2/en not_active Ceased
- 2001-06-18 HU HU0301164A patent/HU228400B1/hu active Protection Beyond IP Right Term
- 2001-06-20 TW TW090114964A patent/TWI289451B/zh not_active IP Right Cessation
-
2002
- 2002-12-02 IL IL153229A patent/IL153229A/en active IP Right Grant
- 2002-12-19 NO NO20026117A patent/NO330459B1/no not_active IP Right Cessation
-
2005
- 2005-05-31 JP JP2005159852A patent/JP5005188B2/ja not_active Expired - Lifetime
-
2012
- 2012-12-14 CY CY20121101222T patent/CY1113740T1/el unknown
-
2013
- 2013-03-22 CY CY2013011C patent/CY2013011I2/el unknown
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