JP2005102701A5 - - Google Patents
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- JP2005102701A5 JP2005102701A5 JP2004338711A JP2004338711A JP2005102701A5 JP 2005102701 A5 JP2005102701 A5 JP 2005102701A5 JP 2004338711 A JP2004338711 A JP 2004338711A JP 2004338711 A JP2004338711 A JP 2004338711A JP 2005102701 A5 JP2005102701 A5 JP 2005102701A5
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- Prior art keywords
- amino acid
- pharmaceutical composition
- antigenic
- acid residues
- ige
- Prior art date
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Claims (15)
- 配列番号:8又は配列番号:11のアミノ酸配列を含んでなる、又はそのフラグメントである、抗原性ペプチド。
- 異種担体タンパク質に連結された請求項1に記載の抗原性ペプチドを含んでなる、抗原性融合タンパク質。
- 医薬担体の一以上、及び免疫原的に有効な量の請求項1に記載の抗原性ペプチドの一以上を含む、医薬組成物。
- 医薬担体の一以上、及び請求項2に記載の抗原性融合タンパク質の一以上を含む、医薬組成物。
- 請求項3又は4に記載の医薬組成物であって、フラグメントが、少なくとも5アミノ酸残基長、少なくとも10アミノ酸残基長、少なくとも15アミノ酸残基長、少なくとも20アミノ酸残基長、少なくとも25アミノ酸残基長、又は少なくとも30アミノ酸残基長である、医薬組成物。
- さらにアジュバントを含む、請求項3〜5のいずれか1項に記載の医薬組成物。
- IgE介在性アレルギー障害の治療又は予防のための、請求項3〜6のいずれか1項に記載の医薬組成物。
- IgE介在性アレルギー障害の治療又は予防のための医薬の製造のための、請求項3〜6のいずれか1項に記載の医薬組成物の使用。
- IgE介在性アレルギー障害が、喘息、アレルギー性鼻炎、胃腸のアレルギー、食物アレルギー、好酸球増加症、結膜炎、糸球体腎炎及び移植片対宿主病からなる群より選択される、請求項7に記載の医薬組成物又は請求項8に記載の使用。
- 請求項1に記載の抗原性ペプチド又は請求項2に記載の抗原性融合タンパク質をコードする、ポリヌクレオチド。
- 請求項10に記載のポリヌクレオチドを含む発現ベクターを包含する、宿主細胞。
- 配列番号:22又は配列番号:25のポリヌクレオチド配列を含んでなる、ポリヌクレオチド。
- 請求項1に記載の抗原性ペプチド又は請求項2に記載の抗原性融合タンパク質を製造する方法であって、請求項11に記載の宿主細胞の培養物を好適な培地で増殖させ、そして培養物からペプチド又はタンパク質を精製する、製造方法。
- IgE介在性アレルギー障害の治療又は予防方法であって、そのような治療又は予防が所望される非ヒト動物へ、免疫原的に有効な量の請求項1に記載の抗原性ペプチド又は請求項2に記載の抗原性融合タンパク質を投与することを含む、方法。
- IgE介在性アレルギー障害の治療又は予防方法であって、そのような治療又は予防が所望される非ヒト動物へ、免疫原的に有効な量の請求項10に記載のポリヌクレオチドを投与することを含む、方法。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22898900P | 2000-08-30 | 2000-08-30 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001261760A Division JP2002281984A (ja) | 2000-08-30 | 2001-08-30 | 抗IgEワクチン |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012080895A Division JP2012161322A (ja) | 2000-08-30 | 2012-03-30 | 抗IgEワクチン |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005102701A JP2005102701A (ja) | 2005-04-21 |
JP2005102701A5 true JP2005102701A5 (ja) | 2011-04-21 |
Family
ID=22859366
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001261760A Pending JP2002281984A (ja) | 2000-08-30 | 2001-08-30 | 抗IgEワクチン |
JP2004244935A Pending JP2005043374A (ja) | 2000-08-30 | 2004-08-25 | 抗IgEワクチン |
JP2004338711A Pending JP2005102701A (ja) | 2000-08-30 | 2004-11-24 | 抗IgEワクチン |
JP2012080895A Pending JP2012161322A (ja) | 2000-08-30 | 2012-03-30 | 抗IgEワクチン |
JP2012232974A Pending JP2013056904A (ja) | 2000-08-30 | 2012-10-22 | 抗IgEワクチン |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001261760A Pending JP2002281984A (ja) | 2000-08-30 | 2001-08-30 | 抗IgEワクチン |
JP2004244935A Pending JP2005043374A (ja) | 2000-08-30 | 2004-08-25 | 抗IgEワクチン |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012080895A Pending JP2012161322A (ja) | 2000-08-30 | 2012-03-30 | 抗IgEワクチン |
JP2012232974A Pending JP2013056904A (ja) | 2000-08-30 | 2012-10-22 | 抗IgEワクチン |
Country Status (4)
Country | Link |
---|---|
US (5) | US6887472B2 (ja) |
EP (5) | EP2361635A3 (ja) |
JP (5) | JP2002281984A (ja) |
CA (5) | CA2674885C (ja) |
Families Citing this family (28)
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US6887472B2 (en) * | 2000-08-30 | 2005-05-03 | Pfizer Inc. | Anti-IgE vaccines |
EP2330187B1 (en) * | 2001-05-15 | 2016-07-27 | Janssen Pharmaceuticals, Inc. | CD8+ T cells specific for peptide WVDNKTFSV that are specifically cytotoxic for IgE-positive target cells and methods of production. |
JP2003047482A (ja) * | 2001-05-22 | 2003-02-18 | Pfizer Prod Inc | 非アナフィラキシー誘発性IgEワクチン |
ES2316780T3 (es) * | 2002-09-05 | 2009-04-16 | Resistentia Pharmaceuticals Ab | Vacunas contra alergia. |
US9320792B2 (en) | 2002-11-08 | 2016-04-26 | Ablynx N.V. | Pulmonary administration of immunoglobulin single variable domains and constructs thereof |
US20100003253A1 (en) * | 2002-11-08 | 2010-01-07 | Ablynx N.V. | Single domain antibodies directed against epidermal growth factor receptor and uses therefor |
US20060034845A1 (en) * | 2002-11-08 | 2006-02-16 | Karen Silence | Single domain antibodies directed against tumor necrosis factor alpha and uses therefor |
CA2505326A1 (en) * | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Camelidae antibodies against immunoglobulin e and use thereof for the treatment of allergic disorders |
PT2316852E (pt) * | 2002-11-08 | 2014-06-23 | Ablynx Nv | Anticorpos de domínio único estáveis |
KR101365375B1 (ko) | 2004-02-02 | 2014-02-19 | 타녹스 인코퍼레이티드 | 신규한 IgE 에피토프의 확인 |
JP4520923B2 (ja) * | 2005-09-28 | 2010-08-11 | 本田技研工業株式会社 | エンジン始動装置 |
JP2007172129A (ja) * | 2005-12-20 | 2007-07-05 | Sony Corp | 不揮発性メモリアクセス制御装置および不揮発性メモリ制御システム |
AU2013204233B2 (en) * | 2008-12-09 | 2015-06-25 | Pfizer Vaccines Llc | IgE CH3 peptide vaccine |
KR101644221B1 (ko) * | 2008-12-09 | 2016-07-29 | 화이자 백신스 엘엘씨 | IgE CH3 펩티드 백신 |
EP2401300B1 (en) * | 2009-02-25 | 2018-01-10 | Academia Sinica | ANTI-C[epsilon]mX ANTIBODIES CAPABLE OF BINDING TO HUMAN mIgE ON B LYMPHOCYTES |
WO2011154878A1 (en) | 2010-06-07 | 2011-12-15 | Pfizer Vaccines Llc | Ige ch3 peptide vaccine |
KR101163472B1 (ko) * | 2010-06-08 | 2012-07-18 | 기아자동차주식회사 | 자동차의 오프닝 웨더스트립 고정구조 |
US9187553B2 (en) * | 2012-01-25 | 2015-11-17 | Swey-Shen Chen | Displaying native human IgE neutralizing FcepsilonRIa-contacting IgE B-cell epitopes by constraining super beta(b)-strands and cystine knots on thermostable protein scaffold |
US9587034B2 (en) | 2012-04-20 | 2017-03-07 | Academia Sinica | Anti-mIgE antibodies that bind to the junction between CH4 and CεmX domains |
CN102660569B (zh) * | 2012-04-21 | 2013-11-06 | 大连理工大学 | 一种重组人IgE受体蛋白的制备方法及应用 |
JP5918851B2 (ja) * | 2012-06-18 | 2016-05-18 | 日本全薬工業株式会社 | IgEペプチドワクチン |
JP6739702B2 (ja) * | 2014-06-11 | 2020-08-12 | 国立研究開発法人理化学研究所 | 多重同種抗原ペプチド |
WO2016164920A1 (en) * | 2015-04-09 | 2016-10-13 | Cornell University | Gene therapy to prevent reactions to allergens |
AU2018360999A1 (en) | 2017-10-31 | 2020-05-14 | Oneness Biotech Co. Ltd. | Treating IgE-mediated allergic diseases |
US11857623B2 (en) * | 2020-08-07 | 2024-01-02 | King Abdulaziz University | Pan-antiallergy vaccine |
EP4431528A1 (en) * | 2021-10-29 | 2024-09-18 | Longbio Pharma (Suzhou) Co., Ltd. | Isolated antigen binding protein and use thereof |
CN115873867B (zh) * | 2022-09-28 | 2023-06-23 | 云南省农业科学院农业环境资源研究所 | 一种抗稻瘟病基因Pi69及其编码蛋白与应用 |
CN116143932A (zh) * | 2022-12-07 | 2023-05-23 | 南开大学 | 一种针对IgE的抗体或其抗原结合片段以及Fc变体 |
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US6887472B2 (en) | 2000-08-30 | 2005-05-03 | Pfizer Inc. | Anti-IgE vaccines |
JP2003047482A (ja) | 2001-05-22 | 2003-02-18 | Pfizer Prod Inc | 非アナフィラキシー誘発性IgEワクチン |
-
2001
- 2001-08-24 US US09/938,700 patent/US6887472B2/en not_active Expired - Fee Related
- 2001-08-24 EP EP10183753A patent/EP2361635A3/en not_active Withdrawn
- 2001-08-24 EP EP08156884A patent/EP1967205B1/en not_active Expired - Lifetime
- 2001-08-24 EP EP09154655A patent/EP2065052A3/en not_active Ceased
- 2001-08-24 EP EP08156885A patent/EP1967206B1/en not_active Expired - Lifetime
- 2001-08-24 EP EP01307247A patent/EP1195161A3/en not_active Withdrawn
- 2001-08-28 CA CA2674885A patent/CA2674885C/en not_active Expired - Fee Related
- 2001-08-28 CA CA2674838A patent/CA2674838C/en not_active Expired - Fee Related
- 2001-08-28 CA CA2674837A patent/CA2674837C/en not_active Expired - Fee Related
- 2001-08-28 CA CA002356124A patent/CA2356124A1/en not_active Abandoned
- 2001-08-28 CA CA002674888A patent/CA2674888A1/en not_active Abandoned
- 2001-08-30 JP JP2001261760A patent/JP2002281984A/ja active Pending
-
2004
- 2004-01-05 US US10/751,743 patent/US20040146504A1/en not_active Abandoned
- 2004-08-25 JP JP2004244935A patent/JP2005043374A/ja active Pending
- 2004-11-24 JP JP2004338711A patent/JP2005102701A/ja active Pending
-
2005
- 2005-08-04 US US11/196,897 patent/US7897151B2/en not_active Expired - Fee Related
-
2009
- 2009-11-24 US US12/624,566 patent/US8273356B2/en not_active Expired - Fee Related
-
2012
- 2012-03-30 JP JP2012080895A patent/JP2012161322A/ja active Pending
- 2012-08-22 US US13/591,288 patent/US20120321651A1/en not_active Abandoned
- 2012-10-22 JP JP2012232974A patent/JP2013056904A/ja active Pending
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