RU2007127921A - Вакцины и их применение - Google Patents
Вакцины и их применение Download PDFInfo
- Publication number
- RU2007127921A RU2007127921A RU2007127921/13A RU2007127921A RU2007127921A RU 2007127921 A RU2007127921 A RU 2007127921A RU 2007127921/13 A RU2007127921/13 A RU 2007127921/13A RU 2007127921 A RU2007127921 A RU 2007127921A RU 2007127921 A RU2007127921 A RU 2007127921A
- Authority
- RU
- Russia
- Prior art keywords
- polypeptide
- polynucleotide
- polypeptide according
- polynucleotide according
- vaccine
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 229920001184 polypeptide Polymers 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 10
- 102000040430 polynucleotide Human genes 0.000 claims 7
- 108091033319 polynucleotide Proteins 0.000 claims 7
- 239000002157 polynucleotide Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 4
- 201000009906 Meningitis Diseases 0.000 claims 2
- 241000588653 Neisseria Species 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Claims (9)
1. Полипептид, содержащий аминокислотную последовательность, выбранную из SEQ ID №2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, или его фрагмент или вариант, или слитая конструкция такого фрагмента или варианта.
2. Полинуклеотид, кодирующий полипептид по п.1.
3. Полипептид по п.1 или полинуклеотид по п.2 для применения в медицине.
4. Полипептид по п.1 или полинуклеотид по п.2 для применения в вакцине.
5. Способ получения полипептида по п.1, где способ включает экспрессию полинуклеотида по п.2 в клетке хозяина и выделение упомянутого пептида.
6. Способ получения полипептида по п.1, включающий химически синтезированный указанный полипептид.
7. Способ вакцинации индивидуума против Neisseria meningitides, включающий введение индивидууму полипептида по п.1 или полинуклеотида по п.2.
8. Применение полипептида по п.1 или полинуклеотида по п.2 в производстве вакцины для вакцинации индивидуумов против Neisseria meningitides.
9. Фармацевтическая композиция, содержащая полипептид по п.1 или полинуклеотид по п.2 и фармацевтически приемлемый носитель.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2004/005441 WO2005060995A2 (en) | 2003-12-23 | 2004-12-23 | Identification of antigenically important neisseria antigens by screening insertional mutant libraries with antiserum |
| GBPCT/GB2004/005441 | 2004-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2007127921A true RU2007127921A (ru) | 2009-01-27 |
Family
ID=36282716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007127921/13A RU2007127921A (ru) | 2004-12-23 | 2005-12-23 | Вакцины и их применение |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1848457A2 (ru) |
| JP (1) | JP2008525008A (ru) |
| KR (1) | KR20070094762A (ru) |
| CN (2) | CN101115502A (ru) |
| AU (1) | AU2005317835A1 (ru) |
| CA (1) | CA2592156A1 (ru) |
| MX (1) | MX2007007886A (ru) |
| NO (1) | NO20073256L (ru) |
| RU (1) | RU2007127921A (ru) |
| WO (1) | WO2006067518A2 (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090226479A1 (en) * | 2005-12-23 | 2009-09-10 | Imperial Innovations Limited | Vaccines and their use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9814902D0 (en) * | 1998-07-10 | 1998-09-09 | Univ Nottingham | Screening of neisserial vaccine candidates against pathogenic neisseria |
-
2005
- 2005-12-23 CA CA002592156A patent/CA2592156A1/en not_active Abandoned
- 2005-12-23 KR KR1020077015481A patent/KR20070094762A/ko not_active Application Discontinuation
- 2005-12-23 RU RU2007127921/13A patent/RU2007127921A/ru not_active Application Discontinuation
- 2005-12-23 MX MX2007007886A patent/MX2007007886A/es unknown
- 2005-12-23 WO PCT/GB2005/005113 patent/WO2006067518A2/en active Application Filing
- 2005-12-23 AU AU2005317835A patent/AU2005317835A1/en not_active Abandoned
- 2005-12-23 CN CNA2005800479621A patent/CN101115502A/zh active Pending
- 2005-12-23 JP JP2007547670A patent/JP2008525008A/ja active Pending
- 2005-12-23 EP EP05823115A patent/EP1848457A2/en not_active Withdrawn
-
2006
- 2006-12-21 CN CNA2006800516894A patent/CN101370514A/zh active Pending
-
2007
- 2007-06-25 NO NO20073256A patent/NO20073256L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101370514A (zh) | 2009-02-18 |
| JP2008525008A (ja) | 2008-07-17 |
| CN101115502A (zh) | 2008-01-30 |
| MX2007007886A (es) | 2008-01-16 |
| AU2005317835A1 (en) | 2006-06-29 |
| WO2006067518A3 (en) | 2006-11-23 |
| EP1848457A2 (en) | 2007-10-31 |
| CA2592156A1 (en) | 2006-06-29 |
| NO20073256L (no) | 2007-09-17 |
| WO2006067518A2 (en) | 2006-06-29 |
| KR20070094762A (ko) | 2007-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20090121 |