WO2006067518A3 - Vaccines against neisseria meningitidis - Google Patents

Vaccines against neisseria meningitidis Download PDF

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Publication number
WO2006067518A3
WO2006067518A3 PCT/GB2005/005113 GB2005005113W WO2006067518A3 WO 2006067518 A3 WO2006067518 A3 WO 2006067518A3 GB 2005005113 W GB2005005113 W GB 2005005113W WO 2006067518 A3 WO2006067518 A3 WO 2006067518A3
Authority
WO
WIPO (PCT)
Prior art keywords
neisseria meningitidis
vaccines against
against neisseria
fragment
variant
Prior art date
Application number
PCT/GB2005/005113
Other languages
French (fr)
Other versions
WO2006067518A2 (en
Inventor
Christoph Marcel Tang
Yanwen Li
Original Assignee
Imp Innovations Ltd
Christoph Marcel Tang
Yanwen Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2004/005441 external-priority patent/WO2005060995A2/en
Application filed by Imp Innovations Ltd, Christoph Marcel Tang, Yanwen Li filed Critical Imp Innovations Ltd
Priority to JP2007547670A priority Critical patent/JP2008525008A/en
Priority to US11/722,690 priority patent/US20080138357A1/en
Priority to AU2005317835A priority patent/AU2005317835A1/en
Priority to MX2007007886A priority patent/MX2007007886A/en
Priority to EP05823115A priority patent/EP1848457A2/en
Priority to CA002592156A priority patent/CA2592156A1/en
Publication of WO2006067518A2 publication Critical patent/WO2006067518A2/en
Publication of WO2006067518A3 publication Critical patent/WO2006067518A3/en
Priority to JP2008546628A priority patent/JP2009520491A/en
Priority to EP06831443A priority patent/EP1976556A2/en
Priority to PCT/GB2006/004877 priority patent/WO2007072032A2/en
Priority to US12/158,919 priority patent/US20090226479A1/en
Priority to RU2008130395/13A priority patent/RU2008130395A/en
Priority to CA002634911A priority patent/CA2634911A1/en
Priority to KR1020087017965A priority patent/KR20080090447A/en
Priority to AU2006328153A priority patent/AU2006328153A1/en
Priority to NO20073256A priority patent/NO20073256L/en
Priority to NO20082810A priority patent/NO20082810L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Various polypeptides, or a variant or fragment thereof or a fusion of these are described which are useful in a vaccine. The polypeptide may be a polypeptide comprising the amino acid sequence selected from any one of SEQ ID Nos (2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68); or a fragment or variant thereof or a fusion of such fragment or variant, and is useful in a vaccine against Neisseira meningitidis.
PCT/GB2005/005113 2004-12-23 2005-12-23 Vaccines against neisseria meningitidis WO2006067518A2 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP2007547670A JP2008525008A (en) 2004-12-23 2005-12-23 Vaccine against Neisseria meningitidis
US11/722,690 US20080138357A1 (en) 2005-12-23 2005-12-23 Vaccines Against Neisseria Meningitidis
AU2005317835A AU2005317835A1 (en) 2004-12-23 2005-12-23 Vaccines against Neisseria meningitidis
MX2007007886A MX2007007886A (en) 2004-12-23 2005-12-23 Vaccines and their use.
EP05823115A EP1848457A2 (en) 2004-12-23 2005-12-23 Vaccines against neisseria meningitidis
CA002592156A CA2592156A1 (en) 2004-12-23 2005-12-23 Vaccines against neisseria meningitidis
AU2006328153A AU2006328153A1 (en) 2005-12-23 2006-12-21 Neisseria meningitidis vaccines and their use
KR1020087017965A KR20080090447A (en) 2005-12-23 2006-12-21 Neisseria meningitidis vaccines and their use
CA002634911A CA2634911A1 (en) 2005-12-23 2006-12-21 Neisseria meningitidis vaccines and their use
JP2008546628A JP2009520491A (en) 2005-12-23 2006-12-21 Vaccine against Neisseria meningitidis
EP06831443A EP1976556A2 (en) 2005-12-23 2006-12-21 Neisseria meningitidis vaccines and their use
PCT/GB2006/004877 WO2007072032A2 (en) 2005-12-23 2006-12-21 Neisseria meningitidis vaccines and their use
US12/158,919 US20090226479A1 (en) 2005-12-23 2006-12-21 Vaccines and their use
RU2008130395/13A RU2008130395A (en) 2005-12-23 2006-12-21 VACCINES AND THEIR APPLICATION
NO20073256A NO20073256L (en) 2004-12-23 2007-06-25 Vaccines against meningococcus
NO20082810A NO20082810L (en) 2005-12-23 2008-06-23 Vaccine, and use of the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBPCT/GB2004/005441 2004-12-23
PCT/GB2004/005441 WO2005060995A2 (en) 2003-12-23 2004-12-23 Identification of antigenically important neisseria antigens by screening insertional mutant libraries with antiserum

Publications (2)

Publication Number Publication Date
WO2006067518A2 WO2006067518A2 (en) 2006-06-29
WO2006067518A3 true WO2006067518A3 (en) 2006-11-23

Family

ID=36282716

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/005113 WO2006067518A2 (en) 2004-12-23 2005-12-23 Vaccines against neisseria meningitidis

Country Status (10)

Country Link
EP (1) EP1848457A2 (en)
JP (1) JP2008525008A (en)
KR (1) KR20070094762A (en)
CN (2) CN101115502A (en)
AU (1) AU2005317835A1 (en)
CA (1) CA2592156A1 (en)
MX (1) MX2007007886A (en)
NO (1) NO20073256L (en)
RU (1) RU2007127921A (en)
WO (1) WO2006067518A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007072032A2 (en) * 2005-12-23 2007-06-28 Imperial Innovations Limited Neisseria meningitidis vaccines and their use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000003003A2 (en) * 1998-07-10 2000-01-20 The University Of Nottingham Screening of neisserial vaccine candidates and vaccines against pathogenic neisseria

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000003003A2 (en) * 1998-07-10 2000-01-20 The University Of Nottingham Screening of neisserial vaccine candidates and vaccines against pathogenic neisseria

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KIZIL G ET AL: "IDENTIFICATION AND CHARACTERIZATION OF TSPA, A MAJOR CD4+ T-CELL- AND B-CELL-STIMULATING NEISSERIA-SPECIFIC ANTIGEN", INFECTION AND IMMUNITY, AMERICAN SOCIETY OF MICROBIOLOGY, WASHINGTON, DC, US, vol. 67, no. 7, July 1999 (1999-07-01), pages 3533 - 3541, XP000885437, ISSN: 0019-9567 *
TETTELIN H ET AL: "COMPLETE GENOME SEQUENCE OF NEISSERIA MENINGTIDIS SEROGROUP B STRAIN MC58", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 287, 10 March 2000 (2000-03-10), pages 1809 - 1815, XP001019215, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
AU2005317835A1 (en) 2006-06-29
NO20073256L (en) 2007-09-17
JP2008525008A (en) 2008-07-17
WO2006067518A2 (en) 2006-06-29
RU2007127921A (en) 2009-01-27
MX2007007886A (en) 2008-01-16
KR20070094762A (en) 2007-09-21
EP1848457A2 (en) 2007-10-31
CN101370514A (en) 2009-02-18
CN101115502A (en) 2008-01-30
CA2592156A1 (en) 2006-06-29

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