JP2005097255A5 - - Google Patents
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- Publication number
- JP2005097255A5 JP2005097255A5 JP2004212054A JP2004212054A JP2005097255A5 JP 2005097255 A5 JP2005097255 A5 JP 2005097255A5 JP 2004212054 A JP2004212054 A JP 2004212054A JP 2004212054 A JP2004212054 A JP 2004212054A JP 2005097255 A5 JP2005097255 A5 JP 2005097255A5
- Authority
- JP
- Japan
- Prior art keywords
- dunaliella
- preparation
- use according
- effective amount
- fibrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000195634 Dunaliella Species 0.000 claims 12
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 102000023984 PPAR alpha Human genes 0.000 claims 6
- YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 claims 6
- 108020005497 Nuclear hormone receptor Proteins 0.000 claims 5
- 239000012190 activator Substances 0.000 claims 5
- 102000006255 nuclear receptors Human genes 0.000 claims 5
- 108020004017 nuclear receptors Proteins 0.000 claims 5
- 108091008725 peroxisome proliferator-activated receptors alpha Proteins 0.000 claims 5
- ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 claims 4
- 102000000536 PPAR gamma Human genes 0.000 claims 4
- 108010016731 PPAR gamma Proteins 0.000 claims 4
- 229940123464 Thiazolidinedione Drugs 0.000 claims 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 229940125753 fibrate Drugs 0.000 claims 4
- HYAFETHFCAUJAY-UHFFFAOYSA-N pioglitazone Chemical compound N1=CC(CC)=CC=C1CCOC(C=C1)=CC=C1CC1C(=O)NC(=O)S1 HYAFETHFCAUJAY-UHFFFAOYSA-N 0.000 claims 4
- 239000000843 powder Substances 0.000 claims 4
- 241000195493 Cryptophyta Species 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- AFSHNJLKCYAWRX-UHFFFAOYSA-N 4-[(5-chloronaphthalen-2-yl)methyl]-5h-1,2,3,5-oxathiadiazole 2-oxide Chemical compound C=1C=C2C(Cl)=CC=CC2=CC=1CC1=NS(=O)ON1 AFSHNJLKCYAWRX-UHFFFAOYSA-N 0.000 claims 2
- MVDXXGIBARMXSA-PYUWXLGESA-N 5-[[(2r)-2-benzyl-3,4-dihydro-2h-chromen-6-yl]methyl]-1,3-thiazolidine-2,4-dione Chemical compound S1C(=O)NC(=O)C1CC1=CC=C(O[C@@H](CC=2C=CC=CC=2)CC2)C2=C1 MVDXXGIBARMXSA-PYUWXLGESA-N 0.000 claims 2
- YVQKIDLSVHRBGZ-UHFFFAOYSA-N 5-[[4-[2-hydroxy-2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione Chemical compound CC=1OC(C=2C=CC=CC=2)=NC=1C(O)COC(C=C1)=CC=C1CC1SC(=O)NC1=O YVQKIDLSVHRBGZ-UHFFFAOYSA-N 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- KPSRODZRAIWAKH-JTQLQIEISA-N Ciprofibrate Natural products C1=CC(OC(C)(C)C(O)=O)=CC=C1[C@H]1C(Cl)(Cl)C1 KPSRODZRAIWAKH-JTQLQIEISA-N 0.000 claims 2
- HEMJJKBWTPKOJG-UHFFFAOYSA-N Gemfibrozil Chemical compound CC1=CC=C(C)C(OCCCC(C)(C)C(O)=O)=C1 HEMJJKBWTPKOJG-UHFFFAOYSA-N 0.000 claims 2
- 229940080774 Peroxisome proliferator-activated receptor gamma agonist Drugs 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 229940062310 avandia Drugs 0.000 claims 2
- 229960000516 bezafibrate Drugs 0.000 claims 2
- IIBYAHWJQTYFKB-UHFFFAOYSA-N bezafibrate Chemical compound C1=CC(OC(C)(C)C(O)=O)=CC=C1CCNC(=O)C1=CC=C(Cl)C=C1 IIBYAHWJQTYFKB-UHFFFAOYSA-N 0.000 claims 2
- YZFWTZACSRHJQD-UHFFFAOYSA-N ciglitazone Chemical compound C=1C=C(CC2C(NC(=O)S2)=O)C=CC=1OCC1(C)CCCCC1 YZFWTZACSRHJQD-UHFFFAOYSA-N 0.000 claims 2
- 229950009226 ciglitazone Drugs 0.000 claims 2
- 229960002174 ciprofibrate Drugs 0.000 claims 2
- KPSRODZRAIWAKH-UHFFFAOYSA-N ciprofibrate Chemical compound C1=CC(OC(C)(C)C(O)=O)=CC=C1C1C(Cl)(Cl)C1 KPSRODZRAIWAKH-UHFFFAOYSA-N 0.000 claims 2
- 229960001214 clofibrate Drugs 0.000 claims 2
- KNHUKKLJHYUCFP-UHFFFAOYSA-N clofibrate Chemical group CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 KNHUKKLJHYUCFP-UHFFFAOYSA-N 0.000 claims 2
- QQKNSPHAFATFNQ-UHFFFAOYSA-N darglitazone Chemical compound CC=1OC(C=2C=CC=CC=2)=NC=1CCC(=O)C(C=C1)=CC=C1CC1SC(=O)NC1=O QQKNSPHAFATFNQ-UHFFFAOYSA-N 0.000 claims 2
- 229950006689 darglitazone Drugs 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 229950002375 englitazone Drugs 0.000 claims 2
- 229960002297 fenofibrate Drugs 0.000 claims 2
- YMTINGFKWWXKFG-UHFFFAOYSA-N fenofibrate Chemical compound C1=CC(OC(C)(C)C(=O)OC(C)C)=CC=C1C(=O)C1=CC=C(Cl)C=C1 YMTINGFKWWXKFG-UHFFFAOYSA-N 0.000 claims 2
- 229960003627 gemfibrozil Drugs 0.000 claims 2
- 229960005095 pioglitazone Drugs 0.000 claims 2
- 229960004586 rosiglitazone Drugs 0.000 claims 2
- SUFUKZSWUHZXAV-BTJKTKAUSA-N rosiglitazone maleate Chemical group [H+].[H+].[O-]C(=O)\C=C/C([O-])=O.C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O SUFUKZSWUHZXAV-BTJKTKAUSA-N 0.000 claims 2
- GXPHKUHSUJUWKP-UHFFFAOYSA-N troglitazone Chemical compound C1CC=2C(C)=C(O)C(C)=C(C)C=2OC1(C)COC(C=C1)=CC=C1CC1SC(=O)NC1=O GXPHKUHSUJUWKP-UHFFFAOYSA-N 0.000 claims 2
- 229960001641 troglitazone Drugs 0.000 claims 2
- GXPHKUHSUJUWKP-NTKDMRAZSA-N troglitazone Natural products C([C@@]1(OC=2C(C)=C(C(=C(C)C=2CC1)O)C)C)OC(C=C1)=CC=C1C[C@H]1SC(=O)NC1=O GXPHKUHSUJUWKP-NTKDMRAZSA-N 0.000 claims 2
- 241000195633 Dunaliella salina Species 0.000 claims 1
- 108010028924 PPAR alpha Proteins 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/668,601 US7264813B2 (en) | 2003-09-24 | 2003-09-24 | Therapeutic uses of Dunaliella powder |
| US10/668601 | 2003-09-24 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009187809A Division JP5356946B2 (ja) | 2003-09-24 | 2009-08-13 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005097255A JP2005097255A (ja) | 2005-04-14 |
| JP2005097255A5 true JP2005097255A5 (OSRAM) | 2005-09-29 |
| JP5020463B2 JP5020463B2 (ja) | 2012-09-05 |
Family
ID=34313520
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004212054A Expired - Fee Related JP5020463B2 (ja) | 2003-09-24 | 2004-07-20 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2009187809A Expired - Lifetime JP5356946B2 (ja) | 2003-09-24 | 2009-08-13 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2013126599A Withdrawn JP2013177457A (ja) | 2003-09-24 | 2013-06-17 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2016104166A Expired - Fee Related JP6321074B2 (ja) | 2003-09-24 | 2016-05-25 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2017235555A Expired - Lifetime JP6490782B2 (ja) | 2003-09-24 | 2017-12-07 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009187809A Expired - Lifetime JP5356946B2 (ja) | 2003-09-24 | 2009-08-13 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2013126599A Withdrawn JP2013177457A (ja) | 2003-09-24 | 2013-06-17 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2016104166A Expired - Fee Related JP6321074B2 (ja) | 2003-09-24 | 2016-05-25 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2017235555A Expired - Lifetime JP6490782B2 (ja) | 2003-09-24 | 2017-12-07 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US7264813B2 (OSRAM) |
| EP (2) | EP1522310B1 (OSRAM) |
| JP (5) | JP5020463B2 (OSRAM) |
| AT (1) | ATE548046T1 (OSRAM) |
| IL (1) | IL162987A (OSRAM) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007210917A (ja) * | 2006-02-08 | 2007-08-23 | Kochi Univ | 脂肪細胞縮小化剤、医薬品及び飲食品 |
| US20090169586A1 (en) * | 2006-03-24 | 2009-07-02 | Ian Simon Tracton | Stable packaged dosage form and process therefor |
| JP2008222555A (ja) * | 2007-03-08 | 2008-09-25 | Nagasakiken Koritsu Daigaku Hojin | アディポネクチン受容体発現増加剤 |
| WO2009105048A2 (fr) * | 2008-02-19 | 2009-08-27 | Rached Smida | Nouvelles applications du hdl reconstitué |
| WO2009133552A2 (en) * | 2008-04-29 | 2009-11-05 | Nikken Sohonsha Corporation | Methods of treating ophthalmic disorders |
| US20100303989A1 (en) | 2008-10-14 | 2010-12-02 | Solazyme, Inc. | Microalgal Flour |
| JP5733592B2 (ja) * | 2008-10-20 | 2015-06-10 | 株式会社日健総本社 | 脂質異常治療薬の副作用防止物質 |
| US8747834B2 (en) | 2009-03-03 | 2014-06-10 | Solazyme, Inc. | Methods of treating impaired glucose metabolism via administration of algal biomass |
| WO2011070568A1 (en) * | 2009-12-10 | 2011-06-16 | Nikken Sohonsha Corporation | Method for treating psoriasis |
| US9577089B2 (en) | 2010-03-02 | 2017-02-21 | Vishay-Siliconix | Structures and methods of fabricating dual gate devices |
| US10098371B2 (en) | 2013-01-28 | 2018-10-16 | Solazyme Roquette Nutritionals, LLC | Microalgal flour |
| FR3009619B1 (fr) | 2013-08-07 | 2017-12-29 | Roquette Freres | Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee |
| GB201718822D0 (en) | 2017-11-14 | 2017-12-27 | Univ Greenwich | Production of dunaliella |
| JP6947665B2 (ja) * | 2018-03-13 | 2021-10-13 | アイカ工業株式会社 | 光硬化性粘着樹脂組成物 |
| WO2020202152A1 (en) * | 2019-04-01 | 2020-10-08 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Dunaliella alga preparation for prevention and/or treatment of a neurodegenerative disease, a disorder associated with protein misfolding and cognitive decline |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4199895A (en) | 1977-05-25 | 1980-04-29 | Yeda Research And Development Co. Ltd. | Production of glycerol, carotenes and algae meal |
| USPP4511P (en) | 1978-06-26 | 1980-03-18 | Yeda Research & Development Co. Ltd. | Alga strain |
| DE3729209A1 (de) * | 1987-09-01 | 1989-03-09 | Boehringer Mannheim Gmbh | Verwendung von bezafibrat zur behandlung von diabetes |
| US4915965A (en) * | 1988-02-25 | 1990-04-10 | Yoshio Tanaka | Process for production of encapsulated foodstuff containing dunaliella algae |
| US5190970A (en) * | 1990-10-19 | 1993-03-02 | E. R. Squibb & Sons, Inc. | Method for preventing onset of or treating Type II diabetes employing a cholesterol lowering drug alone or in combination with an ace inhibitor |
| US5219888A (en) | 1992-03-31 | 1993-06-15 | American Cyanamid Company | Use of retinoids for the treatment of coronary artery disease |
| EP0643692B1 (en) | 1992-06-04 | 1999-11-24 | Betatene Pty. Ltd. | High cis beta-carotene composition |
| US6262109B1 (en) * | 1995-12-22 | 2001-07-17 | Henkel Corporation | Methods of preventing and/or treating high serum levels of cholesterol and/or lipids |
| DK0859608T3 (da) | 1995-09-18 | 2004-06-14 | Ligand Pharm Inc | Behandling af NIDDM med RXR-agonister |
| WO1997010813A1 (en) * | 1995-09-18 | 1997-03-27 | Ligand Pharmaceuticals Incorporated | Ppar gamma antagonists for treating obesity |
| IL119224A (en) | 1996-09-09 | 2002-11-10 | Hadasit Med Res Service | Medicament for protection from effects of irradiation |
| JP3037628B2 (ja) * | 1997-03-06 | 2000-04-24 | マイクロアルジェコーポレーション株式会社 | 健康補助食品用軟カプセルの製法 |
| GB9712866D0 (en) * | 1997-06-18 | 1997-08-20 | Smithkline Beecham Plc | Novel method of treatment |
| US6083497A (en) * | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| JP2002516983A (ja) | 1998-03-30 | 2002-06-11 | ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア | 核受容体活性を調節するための方法及び化合物 |
| JP2000080047A (ja) * | 1998-06-30 | 2000-03-21 | Takeda Chem Ind Ltd | 医 薬 |
| KR20010043455A (ko) | 1998-06-30 | 2001-05-25 | 다케다 야쿠힌 고교 가부시키가이샤 | 당뇨병 치료용 약학적 조성물 |
| IL126447A (en) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| EP1140186B1 (en) * | 1998-12-23 | 2003-06-04 | G.D. Searle LLC. | Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications |
| US6914073B2 (en) * | 1999-03-18 | 2005-07-05 | Bristol Myers Squibb Company | Vitamin formulation for cardiovascular health |
| FR2795961B1 (fr) | 1999-07-09 | 2004-05-28 | Ethypharm Lab Prod Ethiques | Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation |
| WO2001019770A2 (en) | 1999-09-14 | 2001-03-22 | Ligand Pharmaceuticals Incorporated | Rxr modulators with improved pharmacologic profile |
| US6680387B2 (en) * | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| GB0019226D0 (en) * | 2000-08-04 | 2000-09-27 | Smithkline Beecham Plc | Novel pharmaceutical |
| AU2002333655A1 (en) | 2001-09-25 | 2003-04-07 | Smithkline Beecham Corporation | Bicyclic heterocycles as rxr ligands |
| IN189624B (OSRAM) * | 2001-10-23 | 2003-03-29 | Ajanta Pharma Ltd | |
| JP3978582B2 (ja) * | 2001-12-19 | 2007-09-19 | 株式会社日健総本社 | カロチノイドの製造方法 |
| US20030212138A1 (en) * | 2002-01-14 | 2003-11-13 | Pharmacia Corporation | Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor |
-
2003
- 2003-09-24 US US10/668,601 patent/US7264813B2/en not_active Expired - Lifetime
-
2004
- 2004-07-13 IL IL162987A patent/IL162987A/en active IP Right Grant
- 2004-07-20 JP JP2004212054A patent/JP5020463B2/ja not_active Expired - Fee Related
- 2004-08-12 AT AT04019206T patent/ATE548046T1/de active
- 2004-08-12 EP EP04019206A patent/EP1522310B1/en not_active Expired - Lifetime
- 2004-08-12 EP EP10010882A patent/EP2269620A1/en not_active Withdrawn
-
2007
- 2007-07-10 US US11/822,786 patent/US7763255B2/en not_active Expired - Lifetime
-
2009
- 2009-08-13 JP JP2009187809A patent/JP5356946B2/ja not_active Expired - Lifetime
-
2010
- 2010-05-11 US US12/777,757 patent/US8343549B2/en not_active Expired - Fee Related
-
2013
- 2013-06-17 JP JP2013126599A patent/JP2013177457A/ja not_active Withdrawn
-
2016
- 2016-05-25 JP JP2016104166A patent/JP6321074B2/ja not_active Expired - Fee Related
-
2017
- 2017-12-07 JP JP2017235555A patent/JP6490782B2/ja not_active Expired - Lifetime
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