JP2004538305A5 - - Google Patents
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- Publication number
- JP2004538305A5 JP2004538305A5 JP2003516519A JP2003516519A JP2004538305A5 JP 2004538305 A5 JP2004538305 A5 JP 2004538305A5 JP 2003516519 A JP2003516519 A JP 2003516519A JP 2003516519 A JP2003516519 A JP 2003516519A JP 2004538305 A5 JP2004538305 A5 JP 2004538305A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- alkyl
- phenyl
- composition
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 16
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 13
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 10
- 229910052739 hydrogen Inorganic materials 0.000 claims 9
- 239000001257 hydrogen Substances 0.000 claims 9
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 8
- 125000001475 halogen functional group Chemical group 0.000 claims 6
- 125000001544 thienyl group Chemical group 0.000 claims 6
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 6
- 208000002193 Pain Diseases 0.000 claims 5
- 125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 claims 4
- 208000000094 Chronic Pain Diseases 0.000 claims 4
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 3
- 125000002541 furyl group Chemical group 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 125000004076 pyridyl group Chemical group 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 125000000335 thiazolyl group Chemical group 0.000 claims 3
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 125000001624 naphthyl group Chemical group 0.000 claims 2
- 208000004296 neuralgia Diseases 0.000 claims 2
- 125000003261 o-tolyl group Chemical group [H]C1=C([H])C(*)=C(C([H])=C1[H])C([H])([H])[H] 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30908401P | 2001-07-31 | 2001-07-31 | |
| PCT/US2002/021301 WO2003011289A1 (en) | 2001-07-31 | 2002-07-29 | Treatment of chronic pain with 3-heterocyclyl- and 3-cycloalkyl-3-aryloxypropanamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004538305A JP2004538305A (ja) | 2004-12-24 |
| JP2004538305A5 true JP2004538305A5 (enExample) | 2005-10-06 |
Family
ID=23196615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003516519A Withdrawn JP2004538305A (ja) | 2001-07-31 | 2002-07-29 | 3−ヘテロシクリル−及び3−シクロアルキル−3−アリールオキシプロパンアミンによる慢性疼痛の治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20030087938A1 (enExample) |
| EP (1) | EP1411934A1 (enExample) |
| JP (1) | JP2004538305A (enExample) |
| BR (1) | BR0211533A (enExample) |
| CA (1) | CA2451288A1 (enExample) |
| MX (1) | MXPA04000418A (enExample) |
| WO (1) | WO2003011289A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006063048A2 (en) * | 2004-12-06 | 2006-06-15 | Avigen, Inc. | Ibudilast for treating neuropathic pain and associated syndromes |
| GB0523550D0 (en) | 2005-11-18 | 2005-12-28 | Hunter Fleming Ltd | Therapeutic uses of steroidal compounds |
| US20080181876A1 (en) * | 2007-01-30 | 2008-07-31 | Johnson Kirk W | Methods for treating acute and subchronic pain |
| US20080287402A1 (en) * | 2007-05-03 | 2008-11-20 | Johnson Kirk W | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035511A (en) * | 1976-05-06 | 1977-07-12 | Massachusetts Institute Of Technology | Process for promoting analgesia |
| US4596807A (en) * | 1985-03-26 | 1986-06-24 | Serotonin Industries Of Charleston | Method and compositions for controlling pain, depression and sedation |
| US4956388A (en) * | 1986-12-22 | 1990-09-11 | Eli Lilly And Company | 3-aryloxy-3-substituted propanamines |
| US5250572A (en) * | 1990-03-29 | 1993-10-05 | Eli Lilly And Company | (R)-norfluoxetine in method for occupying serotonin IC receptors |
| US5104899A (en) * | 1990-08-13 | 1992-04-14 | Sepracor, Inc. | Methods and compositions for treating depression using optically pure fluoxetine |
| US5589511A (en) * | 1990-08-13 | 1996-12-31 | Sepracor Inc. | Method for treating migraine headaches using optically pure S(+) fluoxetine |
| ZA958725B (en) * | 1994-10-20 | 1997-04-16 | Lilly Co Eli | Treatment of disorders with duloxetine |
| US5942530A (en) * | 1997-08-28 | 1999-08-24 | Eli Lilly And Company | Method for treating pain |
| PT1113797E (pt) * | 1998-09-15 | 2009-12-21 | Lilly Co Eli | Utilização da duloxetina para o tratamento da fibromialgia |
| GB0004153D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel use |
-
2002
- 2002-07-29 EP EP02748080A patent/EP1411934A1/en not_active Withdrawn
- 2002-07-29 MX MXPA04000418A patent/MXPA04000418A/es not_active Application Discontinuation
- 2002-07-29 CA CA002451288A patent/CA2451288A1/en not_active Abandoned
- 2002-07-29 US US10/207,511 patent/US20030087938A1/en not_active Abandoned
- 2002-07-29 BR BR0211533-6A patent/BR0211533A/pt not_active Application Discontinuation
- 2002-07-29 JP JP2003516519A patent/JP2004538305A/ja not_active Withdrawn
- 2002-07-29 WO PCT/US2002/021301 patent/WO2003011289A1/en not_active Ceased
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